Podarcis raffonei (Aeolian wall lizard): 128422286
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Entry
128422286 CDS
T09310
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
praf
Podarcis raffonei (Aeolian wall lizard)
Brite
KEGG Orthology (KO) [BR:
praf00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
praf01001
]
128422286 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
praf04131
]
128422286 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
praf04147
]
128422286 (LRRK2)
Enzymes [BR:
praf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
128422286 (LRRK2)
Protein kinases [BR:
praf01001
]
Serine/threonine kinases: TKL group
LRRK family
128422286 (LRRK2)
Membrane trafficking [BR:
praf04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
128422286 (LRRK2)
Exosome [BR:
praf04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
128422286 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_4
LRR_8
COR
Ras
LRR_1
Arf
WD40_2
LRR_13
LRR_9
Ank_2
WDR55
WD40_CDC20-Fz
Gtr1_RagA
MMR_HSR1
T2SSE
WD40_Prp19
AAA_16
Beta-prop_HPS5
Arm
Kdo
NACHT
AAA_22
PduV-EutP
AAA_7
Beta-prop_RSE1_2nd
G-alpha
cobW
nSTAND3
ABC_tran
TniB
Septin
AAA_29
TrwB_AAD_bind
AAA_15
MobB
FtsK_SpoIIIE
LRR_NXF1-5
Beta-prop_BBS7
Beta-prop_EML_2
GTP_EFTU
UNC45-central
AAA_23
Motif
Other DBs
NCBI-GeneID:
128422286
NCBI-ProteinID:
XP_053262087
LinkDB
All DBs
Position
10:complement(10424172..10510125)
Genome browser
AA seq
2681 aa
AA seq
DB search
MRSPFSPYAALRRAACFCAGQGHFAAPIPSPRVNPAISLRKNPFPRSLAFVFGACASSRF
PPLDEARESEAARPAQLISRLFSPPRLEPGGANGRNESAIYGHGARTAGSFRRRHPSSSS
SVAAERAGGSLLWGCGVCEGGSLRGEGKLVSAEGDMSGGRRGSSRSCRGDEEEREAALQK
LIVRLKNVQEGKQIETLVQILRDLLAFASSPSGPPLLVGKNVHVPLLLVLASYMRVASVQ
QVGWSLLCKLIEVCPDTLHNLAAPQGVGKDWEVLGVHQHILKMLKNHNVNIHLSTVGLKA
LNMLLSSDVITLLLLEEGTDVFLLIFDAMDTFSDNEEIQKYGCKALHVLLEKVPEEQLIE
FVEDRDHMIILNVLKKFPKKENLVLLALLSLHSLAGPPSNAEILMSGNVRCYNVIVEMMK
DFPDNEAIQEVSCCLLHKLALENFFNILVLNDVHQFIVTAVGKYPASAKLQAAGLSCLAL
LTETIFLSRDLEEEEVEEEEKELCWLEACYKALKLHRKNIDVQEAACWALNNLLMYQRNL
HEKIGDGDKKFPAHREMMLSMLMHNSSKELFQAAANALATLLEQSVNIRTVLLAKGIHMN
VLEIMKKHSNSPEVAESACKLLNRAFEGSFPPLDIMTEVASRVVKAMRKHKSSPSVQLEA
LRVILHFMTSGVLKKQPNNSDLGNTELALMLKVIKNQCLLQGAHSLVLDALNTFIGNPGI
QKCGFQVLSSVVECSGALEMLTQQGMTDTVLHTLQMYPDDQEIQCLGLSLLGSLITRKIL
CIAIIQVLAAILVSTLRRFKEVVEIQAHGFNVIIKILDLSPCFAKLLIQESFDTAIFYQM
SMCFTEQRDQQFQSLCCKCFAKIADNDDLKNLMLEKACAEYNTIMVECLLLLGADVNKET
KKNSLIYQICEKGSNPKLVELLLNGGAREQDVRSALTISIKKGDSQVISLLLKKLSLDLA
NSSICLGGFCIGRIEPSWLSPLFPSKQGSFKKQNAGSALARMVLRYQKKSSYEDQSSSSF
EENTDENIKEQLDDWELLPDHLVDSVFCLSDGIDSEGSENSIIVKKKSNSVAVADVHKDR
ALQMCSQTLKRNSKSVGPGSHHEPFKNPRRGQMSSEESHNTPNRLDSSSSSIPDREFIKS
LDLSSNELENIDSISQSSCLTTHLEHLEKLELHQNALPCISEQLCESLKCLTYLDLHSNR
FKSFPPYLWKMPHIAHLDISRNEIGPSLILDSKIVCPSLKLLNLSYNQLSCIPEFLSNVA
QNLEHLILEGNKLSSVCSPLCLKELKVLNISKNAVSFLAENFLKDCLKLETLNAGMNSLE
ATPDLPPNITTLKLSQNNFSSVPEAILLLPHLRSVDLSNNKITTLPGPLHWKTSNLRELL
FNHNQISTLDLNTKAFLWSRLEKLHLSHNNLKEIPPQIGFLENLTSFDVSYNPELRSFPD
EMGKLSRIWDLPLEGLNLNFDFKYVGWKARDIIRFLQQRLKKAVPYNRMKLMIVGNTGSG
KTTLLQQLMKCKRQDMEIPNATVGIDVIDWRVTVKSKTKKELELSVWDFGGQEEFYSAHP
HFMTQRALYLTVYDLSKGEAEVDAMKPWLFNIKARASSSPVILIGTHLDISNDKQRRACV
NKITKELMNQRGFPAIRDYHFVNATEESDAMMKLRKTIIKESLNFKIGDQPVVGQLIPDS
YLELQKRILEECKNVPAEFPVIDHKRLLELVQENQLQLDENELPHAVHFLNESGVLLHFQ
DPALQLSDLYFVDPKWLCKIMAQILTVKVEGFPKYPKGIIKRTDVENFLLKKSKFPKVYM
CKYFRLLEKFQIALPLGEDQLLVPSSLSDNRPVIELPHCENSEIIIRLYEMPYFPMGFWS
RLINRLLEVSPFILSGRERALRPNRMYWRQGIYLNWSPEAYCLVESAVFENNPNSFLKIT
VPSCRKGCILLGQVVDHIDSLMEEWFPGLLEVDVCGEGETLLKKWALYSFEDGEEHQQIL
LDDLLKKAEEGDLLVNPDQPKCTIAIARIAPDLILADLPRNIMLKNEELVFCQTPEFLLG
DGGFGSVYRASYSGNEAAVKIFNKHTSLRLLRQELAVLCHLHHPSLVLLLAAAVRPRMLV
MELAPKGSLDRLLQQDNASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLY
PNSAVIAKIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADVYSFGLLLYDI
LTAGGRILEGMKFPNEFDDLAIHGKLPDPVKEYSCTPWPEVEDLIKKCLKENPQERPTSA
QVYDILNSAELVCLMRYISVPSPFGADCMVAANPSCKKTGIWIGSGNLEAAQISFIDLNS
DGHGCQEIADNRVLCMALVTLSAEKENWIVAGTHSGCLWVFHAEEEKPRHQLQKMSDSVT
CLYCYSYAKQNKQNYFCAGTADGQLAVFKDTAVKCKDAAPLKILQLGTRSTPLMCLRESV
YSCEKNTIWGGCGTKIISFSNDFCVQKIIETKTSQILCHRAHSDANIISIAVDKSIYLAK
KNSYFVEVWDKKAEKLCELIDCMHFLKEEVPNLNKESKQEVAILGRVKSICLQKNTALWI
GTGGGHILLLDLSTRRPIRIIRDFCDSVRFMMTAQLGSLKNVVLVLGYCHKGENKDSEYT
TGIQSCLTIWDINLPHEVQNLRKHIELRQELAEKMKSISLD
NT seq
8046 nt
NT seq
+upstream
nt +downstream
nt
atgaggtcgccattttccccgtatgccgccctcagaagagccgcctgtttttgcgcgggc
caggggcacttcgccgcccccatcccctcaccccgagttaacccagccatctccctccgt
aaaaatccctttccccgctccctcgctttcgttttcggcgcctgcgcctcctcccgcttc
cctccccttgacgaggctcgggaaagcgaagccgccaggccggcccagctcatttcccgc
ctcttttctcctccccgcctcgagcccggcggggcaaacggccgcaacgaaagcgccatc
tacgggcatggggcgcgcactgccggctcctttcgccgccgccacccctcctcctcctcc
tccgtcgcggccgagcgggcaggagggagcctgctgtggggctgcggggtttgtgagggg
ggatccctccgaggtgagggaaagttggtgtccgccgagggagacatgagcggcggccgg
agggggagcagcaggagctgccggggcgacgaggaggagagggaagcggctctccagaag
ctcatcgtccgcctgaagaatgtccaggaagggaagcagatcgagaccctcgtccagatc
ctgagggatctcctcgccttcgcctcgtcgcccagcggtcctcccttgctcgtcggcaag
aacgtccacgtgcctctgttgttggtgctggcctcgtacatgagggtggcgagcgtgcag
caggtgggatggtcgcttctttgcaaacttatcgaagtttgcccagacacgcttcataac
ttagcagcccctcaaggtgttgggaaggattgggaagtgcttggtgttcaccagcacatt
cttaagatgcttaaaaaccacaatgtgaacatacacctttctacagttggcctcaaagca
ttaaatatgcttctctcttcagatgtaataacacttcttctcttggaggaaggaacagac
gtatttttactgatatttgatgccatggacacattttctgataatgaggagatccagaaa
tatggatgtaaagctttgcacgtgcttcttgaaaaagttccagaggagcagctgattgaa
tttgttgaggacagagatcacatgatcatactgaatgtgctcaaaaaattccccaaaaaa
gaaaacttagtacttcttgccctgttgtctttacattcattggcaggaccacctagcaat
gcagaaattcttatgtctggaaatgtgaggtgttacaatgtcatcgttgaaatgatgaaa
gatttccccgacaatgaagcaattcaggaagtgagctgctgcttgttgcacaaacttgca
ttggaaaactttttcaatatcctggtattgaatgatgtacatcaattcattgtaacagct
gttggaaaataccctgctagtgcaaagctgcaggctgcaggcctcagttgcttggctctt
ctcacggaaacaatatttttaagcagagacttggaagaggaggaggtggaggaggaagaa
aaagaattgtgttggctggaagcctgttataaagcattaaaattgcatcggaagaatata
gatgtacaggaggctgcatgttgggctttgaacaatctgcttatgtaccaacgtaatctt
catgagaagattggagatggagacaaaaaattcccagcccacagagaaatgatgctatcc
atgttgatgcataattcttcaaaagaattgtttcaagctgctgcaaatgccttggcaact
ctactggagcaaagcgtaaatattagaacagttctgctggcaaaaggaatacacatgaat
gtgctggagattatgaagaaacactccaactccccggaagttgcagaaagtgcttgcaag
ctgctgaaccgtgcttttgaaggaagtttcccccctctggatataatgacagaagtggca
tcgagagttgtgaaggccatgagaaagcataaatcatccccaagtgtacagctggaggca
ctaagagttattttacattttatgacttcaggcgtactgaaaaagcaaccaaataattct
gacttgggcaatactgagttggcgctaatgctgaaagtgataaaaaaccaatgtttgttg
caaggtgctcactcattagtccttgatgctctcaacacgtttattggaaatcctggtatt
cagaaatgtggatttcaggtactttcttctgttgtggaatgttcaggtgcgctagaaatg
ttgacacagcaaggaatgacagataccgtactccatacgctacagatgtatcctgatgat
caagaaatacagtgcttaggcttaagtcttctgggatccttgattacaagaaagatattg
tgcattgcaattatacaagttctggcggcaatcttggtttctactttacggcgctttaag
gaggttgttgaaatacaggcacatggatttaatgtgattataaaaatacttgacctgtca
ccttgttttgcaaagctgttaatacaggagtcatttgatacagccattttttatcagatg
tccatgtgtttcactgagcaaagagaccagcagtttcagagtctttgttgtaaatgcttt
gctaaaatagctgacaacgatgatttaaaaaacctgatgttggagaaagcctgtgctgag
tataataccattatggttgaatgcttactcttgctgggagctgatgtgaataaggagaca
aagaaaaactctttaatctatcaaatttgtgagaaagggagcaatcctaagttggtagaa
ctgctattaaacggcggtgctcgagagcaggatgtccggagtgctctcacaatcagcatc
aagaagggagatagccaggtcattagcttgctcttaaaaaagcttagtctggatttggcc
aacagcagcatatgtcttggcggtttctgcattggtagaattgaaccttcctggctgagc
cccttgtttccaagtaaacaaggatccttcaagaaacaaaatgcaggctctgcgctggcc
agaatggtgcttagataccaaaagaaaagcagctatgaggaccagtcaagttctagtttt
gaagaaaatactgatgaaaatataaaggagcagcttgatgactgggaacttctccctgac
catttagtcgacagtgttttctgcttgagtgatggtatagatagtgaagggagtgaaaac
tcaattatcgtgaagaagaaatccaactccgtggctgttgcagacgtccacaaagacagg
gccttgcagatgtgttctcagaccctgaaaaggaattccaagtctgtgggacctgggtca
catcacgaaccatttaagaatccaagaagagggcaaatgtcttctgaagaatcgcacaac
accccaaatcgattggacagttcctcttcgtcaatccctgacagggaatttattaagtca
cttgatctttcatcaaatgagctggagaatatagatagcatcagtcaaagctcttgctta
actactcatttggaacatcttgagaagttagagcttcatcaaaatgcccttccatgcatt
tctgaacaattgtgtgagagcttgaagtgtttaacttatctggatctgcacagtaaccgt
tttaaatcgtttcctccatacctgtggaaaatgcctcatatagcacatcttgatatctcc
cgcaatgagattggtccttccttaatcttggattcaaagattgtctgtccatctctaaag
ctactgaatttatcatacaatcaattgtcatgcattcccgaatttctctccaatgttgca
caaaacctggagcaccttatattagaaggtaacaagctttcaagtgtgtgctcaccgtta
tgtttgaaggaactgaaagtgttaaacattagtaagaatgctgtatccttcttggctgag
aattttctaaaagactgtttgaagctggagacactcaatgctgggatgaattcactcgag
gccacacctgatttgccgcctaacataactacattgaaattatctcagaataatttttct
agtgttccagaagcaattcttcttctcccacatctgagatcagtggatttaagcaacaat
aaaatcacaactctgcctgggccacttcattggaaaacgtctaatttaagggagttgctg
tttaatcataatcaaataagcaccctggatctgaatacaaaagctttcttgtggtctcgg
ctcgaaaagcttcacctctcccacaacaacttaaaagagattcctcctcaaattgggttc
cttgaaaacttaacatctttcgatgtaagttacaatccagaattaagaagctttcctgat
gaaatgggaaagttatccagaatatgggatcttcccttggaagggttaaatcttaacttt
gacttcaagtatgtgggatggaaagccagggacattataaggtttcttcaacagcgttta
aagaaagctgtcccttataaccggatgaagctcatgatagttggaaatacaggcagcggt
aaaactacactgttacaacaattaatgaaatgcaagcgacaagacatggaaattcccaat
gcgacagttggcattgatgtgattgactggagggttacagtgaagagtaaaacaaagaaa
gaacttgaattaagtgtctgggattttggaggccaggaggaattctacagtgctcacccc
cactttatgacccagagagctctgtaccttactgtttatgaccttagcaaaggagaggct
gaagtggatgctatgaagccgtggctgtttaatatcaaggcccgagcttcatcttcacct
gtgattctcattggtactcatttagacatctctaatgacaaacagcgtagagcttgtgtc
aacaaaattaccaaggaactgatgaatcagaggggatttccagcaatccgagattaccat
tttgtgaatgctactgaagagtccgatgctatgatgaaacttagaaaaactataataaag
gagagtctgaatttcaaaatcggagaccagcccgttgttggacagctaatcccagacagc
tacctggaacttcagaagagaattttagaggaatgcaaaaatgttccagctgaatttcct
gtgattgaccacaagcggttgttagaattggtgcaagaaaaccagttgcagttggatgaa
aatgaactcccacatgctgttcactttctgaatgaatcaggtgttttgctccattttcaa
gatccagcacttcagctaagcgacttgtattttgtggaccctaaatggctatgtaaaatc
atggcacagatcttgacagtgaaggttgaaggctttcctaagtacccaaagggaatcata
aagcgtactgatgtagagaacttcctgctaaagaaaagcaaatttcctaaggtttacatg
tgtaaatacttcaggcttctggagaagttccagatagcactgccactaggagaagatcag
ctccttgttccaagcagcttgtcagataataggcctgtgatagagttaccacactgtgaa
aactctgaaattatcataaggctgtatgaaatgccctattttcccatgggattctggtcc
aggctaatcaacaggttgcttgaagtgtcgccgtttattctttcaggaagagaacgagct
cttcgtcctaacaggatgtactggaggcaaggcatatatctgaactggtcgcctgaagcc
tattgcctggtggaatcggcagtttttgaaaacaacccaaacagtttcctcaaaattact
gtgccttcctgcagaaaaggttgcatcctcttggggcaagttgttgatcacattgattct
cttatggaagaatggtttccgggcttgctagaagtggatgtttgtggtgaaggagaaaca
ctcttgaaaaaatgggctttgtatagctttgaggatggtgaggagcaccagcaaatatta
cttgatgaccttctgaaaaaagcagaagaaggtgacctcttggtgaatccagatcagcca
aaatgcactattgcaattgcccgaattgctccagacctgatactggccgatttacctaga
aatataatgttgaaaaatgaggaactagtattttgccaaacaccagaatttcttctaggt
gatggtggatttggatctgtataccgtgcttcttacagtggaaatgaggcagctgtaaag
atttttaataagcacacatctcttagacttctaagacaagaacttgcagtgctttgccat
cttcatcaccctagtttagtgctcttgctggctgcagcagtgcgtccccgaatgcttgtc
atggaattggcaccaaaagggtctctagatcgattgctgcaacaagacaatgccagtcta
accagaacactccagcacaggatagctctacatgtagccgatggcttaaggtatcttcat
tcagcaatgataatctaccgcgatctaaagccccacaatgtgcttctctttacactgtat
cccaattcagcggtcattgcaaagattgccgattatggtatcgcccagtattgctgtaga
atggggataaaaacatctgagggcacaccaggcttcagagcaccagaagttgcaagagga
aatgttatttacaatcagcaagctgatgtttattcatttggcttgctcctgtatgacatt
ttaacagctggtgggagaatattagaaggcatgaaatttcctaatgaatttgatgactta
gctatccatggaaaattgccagatcctgtcaaagaatatagctgcaccccctggccagaa
gttgaagatttaattaagaaatgtttgaaagaaaatcctcaggaaagacctacatctgct
caggtttatgatattttgaattcggcagaacttgtctgcttgatgagatacatctcagta
ccctctccttttggagcagattgcatggttgctgcaaatccaagttgtaagaagacagga
atctggataggtagcggaaacttagaagcagcacagatctcatttattgatttaaattca
gatggacacgggtgtcaggaaattgcagataacagagtattgtgtatggccttggtaact
ctttcagcagagaaggagaactggattgtagcaggaactcattctggttgtttgtgggtc
tttcatgcagaagaggagaagcccaggcaccaacttcagaagatgtcggattctgtcaca
tgtctttactgctactcttatgcaaagcaaaacaaacagaactatttttgtgctggtaca
gctgatgggcagctagcggtttttaaagacacagcagtaaagtgcaaagatgctgcacct
ttgaagattttacaacttggaacccgcagcaccccacttatgtgcttaagagaatctgtt
tattcatgtgaaaaaaatacaatctggggaggctgtggaacaaagattatatcattttct
aatgacttctgcgtccaaaaaatcattgagacaaaaacaagccaaatattatgccacagg
gctcacagtgatgccaatatcatttccatagcagtagacaaatccatctacttggcaaag
aaaaacagctattttgtggaagtttgggataaaaaggcagagaagctttgtgaactaatc
gactgcatgcattttctaaaggaggaggtgccaaacctgaataaagaatcaaaacaagaa
gttgctattttgggaagagtgaagagcatctgcctgcagaagaatacagccctttggatt
ggcacagggggaggacatatcttactgcttgacctctcaactcgtcggcccataagaata
ataagggatttctgtgattctgttagattcatgatgacagcccagttagggagcctgaag
aacgtagttctggtgttgggctactgccataaaggtgaaaacaaagacagcgaatacacc
acaggaatacagtcatgtttaactatatgggacattaatctgccacatgaagtgcaaaac
ctgagaaaacatattgagctgagacaagagttagcagaaaaaatgaagagcatttctttg
gattaa
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integrated database retrieval system
