Pieris rapae (cabbage white): 110999146
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Entry
110999146 CDS
T05162
Name
(RefSeq) E3 ubiquitin-protein ligase UBR4 isoform X2
KO
K10691
E3 ubiquitin-protein ligase UBR4 [EC:
2.3.2.27
]
Organism
prap
Pieris rapae (cabbage white)
Brite
KEGG Orthology (KO) [BR:
prap00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
prap04121
]
110999146
Enzymes [BR:
prap01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
110999146
Ubiquitin system [BR:
prap04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
UBR box proteins
110999146
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E3_UbLigase_R4
E3_UBR4_N
zf-UBR
Flu_PB2_1st
Motif
Other DBs
NCBI-GeneID:
110999146
NCBI-ProteinID:
XP_022123761
LinkDB
All DBs
Position
2:complement(11819772..11849790)
Genome browser
AA seq
5202 aa
AA seq
DB search
MITQFLTVFSKMAASGGSIEWSTNVKPILTALYGPFFDKNDAVEIIQAIIKSENEFQKHE
EAYDLFYTCFACLSAHFISINANNIPPDQLSTAQDAFRIILQQILKKLSEAGQSQEDTSN
TLSPNVSVKQLLLPIVALCGIDSNGYPPSDLVILLALLKTAKLPPHGNTNENQTTKSAIS
SPITSLASNTSTSEKQPPTNAQRRSDALLERLTMPLRSQVSNVLPPAPSAIGVMSPASKD
SIECAKDGNAQLSSIDIKKWVASTCASLLMELRAGSTILAICSTLPCLQRYLNRWQTAKE
SDSAPSFHSDAALLYFLVNEVEVCRLALSLPCLEPFSPERIVTLSDVSASWLLCATAQAT
LHQKDEEGEAQTATIVETALNLYSTVGDIFKQSTRAGGYVYQNHLMIGAWVLVCGLHHAL
GGAPGPTPPGKSPAKTPLRPYNLTKMQQSLGVVWVALGGRCLSWLGDLLSDARLEALSSS
SDGPASTPASLHISTHHSAHQRELRLALAAPLHQLLVTLGVVCYRKATNLKRAVVPKDRD
AEADRSEGAAFFRDMRLCSEDSETDDDDSEPLFGLWFESTLVAPDADDDGLTRLGAAAVA
SAAPDSAERGIVPDKAEPYSYISLATDVFTLLTDGIVGGGFERLGRYALQLHEAHHALLA
ALARDLDRESARTDTGTISPCFGARLGALYSSFSSALVRYLHALSGSPTFAALRPSLQQQ
LASAERPNTVPLQVGPRVVKLLGGMVLSKPASERENSILVMWHNLINTLQEYALQPLPSQ
DHDYEDLNVEHAQLMVYLFHSLTLMQKKSVLLSTANAIIKVVETLGINERQRATTLAPHR
LTLSTRLMLLLEYLMKHLYDAPQTLLQQIEWNLVVATGLARPSAETSLGEVGTGSDAGPP
KTRIYCEVPFVEQTYRRLSQDETSMRPKFYALTDTKVNNQENPKFDGLACNFVLGTPHKL
KYPVLVDALLALLNCACVCDGRSNRTSVAARAAAHYCFQTAWRLVTSMPPATPHMDKLQA
GTAADLPSPLPLYALVWAPRADAKKAFNPWLKDALVKQGMYTQYAENLLAGVSSSCDNIK
YSAWLASETVKHLKENLRDGLPALLDVMSCDAALMRLKMCLVETSSPPEAHPFVPHLLRL
LETVLACRRSCASPEGGGSAGPATEVVLSVCGGVPSAGAASPPRLGPALKALLPSDVAAL
LDSRSVDPASSVAPSESAVLELVSAHCELMSDRLEYGIGTSLTMLARSAARLLEIGAAEI
ADSLELTRKTLALIVPALTDGRLEFLAEPLTATLNSIVPQAVKAEEIIHEHILRTTYPAL
CDYSPSAEGMLEHIVRYWEKILDRQAGRAAYEAVFVEGDGEFVLGRILLSAPSTSNPFTD
RVVKLFTKIFASCESEDVSQSLCVGVCKFIGVADRQTLFDLLGHICIYGPSLATAGTANG
SPTETELPTPTCSAPEGHPASLALRNAIRCVLFRTDGEVAPRPDARNERDLPVFDNPVAA
TPAPGAQSETNAQQSGNSETCSWSDCSKDSAGATGGGAAASRVEASSPVGEGAHAALLTA
LCKHVVLHCEEEASERLLVTLIEVSGEGCPPPLLREMCRLADSHSGTLHELLFPAALAWL
SSCVESLGSPEVLEKLEEGTIDNDKTTQQIESACTLLSYLGDALHAIGAPPSHAWRSVSP
TWESPSDLGFDLDYADEQQDDDDTSADDSDEDAVLTNKLCTFTITQREFMNQHWYHCHTC
KMVDGVGVCTVCARVCHRGHDISYAKFGNFFCDCGAKPDFSCQALVKREKSSGGGRTAEE
APPAPSLRRRPSSPTPAALLSPPRRPVLAHNIQGCRSFLASYGKWEWCLERVRTLLCALA
GPVRAACERTAAVGAHGRAQRALAQLHLGEKKFSHTDSLMLPTLGSQEGAFENVRMSYTG
ENGQTIRQLISAHKLRRVAMCCLASPQGRRQHLAVSHEKGKITVLQLSALLKQADSSKHR
LTLTRLSSAPIPFTVLSLSGNAANEDLLAVCGLKECHVLTFNSGGAVADHLVLTTDLEAN
NYIIKAIWLPGSQTQLALVTSNFVKIFDLSKDLDSPTHYFLVPSGKVRDVTFVNQEGVMN
MLCMSSAGHIYWQPLSEESLATLGTFYVTNTLEVLHPEIQDVAGLVGGGGVSIYYSHTLK
MLFFSYAQGKSFLAPLNSVEESVKGTAMITVYGGGGGPKEGGRGKGGAQSLLQWAEVPGH
PGLLTALMQASNNPVVLMLTPSGIHVQEIKVVPAKAKITDMVAVRHWCGAGEQKSTLILL
CEDGSLRMYAADPARTGFWLSGAVQPVHAPRRRARPARPSHAHAVPRKQHQPTPKTSDGA
PQFPIDFFEHCHEMRDAEFGGNDLLQVYNTAQIKHRLNTTGLYVVSTKMSGFTMEVTNSD
PNSVICGIRVLLGSQDVARTPTYVEIYGRAVPTMVVRNRWFDVPLSREESLQSDKKLCIV
FGPSQDPDGVTMVDSVKIYGKNKEQFGWPEENEDPAACQSSGRVPQEAEGATGGGDGPGA
VERLACSALEALELSAGAAVRSGAAAGADAAADAAESLLCVPASPTLHARAQCLLRAVYQ
GDYHQRKDRAVLRYVCASLRELRDATDARNVDPEAYFRLVLLARSVAVARPHNLVRFTPP
TPGKPADGDWSALWKADGSGDEPHACALLVSVLWKLAACRSQARGPPGILSYGLRHTEHT
LHALADIIHAFQLNSDPECVEFGNQIYLSLLLAEDQNISFGAKAALVRVLRPRVKRRRVY
IPSPPNTPGAGSSTNAGRASGSASEVAASEPELGARREPRYVDVDDSLEPMVLLAPDGGL
EALLDIPADADDETMVELAIALSLQEQEQPRRQQPHTPTAPPPPAPGFSDANASPNGSDD
EGSTAATDGSTLRTSPAEAAGSAGEESGGSGADSIGGVSGRSSVYAGPSTSSSQPVASSS
RGLEAESETRKLHALRLSLLSAALDALPSLRNLPGVRAIPFVQVVLMLAGDLDSSVEGDR
ALLDLLLEVLIGELDIQSEEPSVEDRDARRDFQLAIARLETLVSEPDTADESTPPVYERT
NRRELQLVIMRLLSVLMSRWKTCGSREHALSTSCAAHVSRLAAAAFVRAGAPGHCYGVLA
ALLPYWRQKSNSNAAATTPTRQLLKPQPPQPLPDMQPFFVKEYVKSHVLDVFDNYPQLLM
EMAVRLPYQIHKHCDPSHFDSRWRTLLCEYMMNPQTPLRKQVRKLLLLLCDTRERYRQIR
DVHALDTHLNAARALLATDPAYDKLVRLMEHLKACVEIVTPRTGNWQHACRSERRETLPW
LLGAARRLHPHVAPTVLQLLQAALCPPGAQPAAQPTQAGAKDAKAQPEWPKRERSADSDG
YVSDASKFQEQRVPDLVAQIHKQVSQEELKLFVKAFLLETNSTAVRWQAHALLLAIYNNS
SPNKQASLVALLWSLWPTLPQYGRKAAQFVDLLGYFTLKTSKVDSSEYIGSAVDLLRNQN
RLLTSHGNSALYASLGAYVELEGYYLESEPCLVCNNPEVPMATIKLPTIKIDSKFTTTTQ
IVKLVSSHTISRISLRVGDIKRSKMVRGINFYYNNRTVQAVQELKNKPGMWHKAKRVQLQ
SGQTEVRVDFPLPIVACNLMMEYADFYENQQATGESLQCPRCSQSVPANPGVCANCGENV
FQCHKCRAINYDEKDPFLCHACGFCKYAKFDYTLIARPCCVVDSIENDEERKKTVQTIGT
LLDKADRVYRQLIANKPQLESLVHKISEHRVDGRPDENSNTATAALGGGQVNRVIQALAH
KYCVESKGHFEDLSKIIQKVLACRKELVAYDKAQSERQNGEASPAYSVLAQNYDGDLAKE
SGGSCYGCSLCTAEHCLTLLRALASQPDKRAALCGAGLVHELVHHNLHRGTPQSQEEVRA
LICLVTRDNLAATERLCTLLTQRITLSLVGHAASQDHNNSVRPLVLLLGSLVKVQDSIEC
WEVRLRCVVKLWVWCCPKVSEVAGIPPAAHYILKDEALADMPGINTCSPNSHQFALQQVA
LPCLRYMQELMAPLVATPSPAPSALSAAATATTATDDLVEEVKEGDEPHNRTGDLVVDLA
AWLAGRVSQKEWRSLAAPEAAPPADCELPPRDLRLARESVGRWRRRVLLGRGMRRVSLSD
GGWLRPVMFDPSSRIARDTACRVVASLCDSYERTKAVLILLTSFLPEVGAAGEASEQFLQ
LYQRLAAKSPWKQFLALRGVLQQIADLMTDEIEQLHRLEETTLTSDLAQGYALQRLTELL
AMFLEEPGARRAYKGRLVGAVLGGYLSLRRLVVQRTRLTDDTQEKLLELLEEMTTGTEAE
TAEFMAVCIETVQKYPLHDYRTPVFIFERLCSIIYPEENDVGEFFLTLEKDPQQEDFLQG
RMLGNPYSSAEPGMGPLMRDVKNKICTDCELVALLEDDNGMELLVCNKIMSLDLPVKDVF
KKVWCTLGESLEAMRVVYRMRGLLGDATEEFVETLSQTNAEAVDDEQTYRMANVLADCGG
LEAMLRRLAAIQRVGGARALVSTLLRLLSLCVRVRRCVRVLTSTETRALPVLLHALTLAA
AEEKDMPRAELVHQLLEIMERILTVAASESLESFLQFSLTFGGPEHVQALLNCTELTAIR
NNSVSLGHLMRVLAALVYGNDLKMAMLVEHFKPALEFERLDAEQWGEREFRIELFCALCA
NIERNSVGGTLKDYLISLGVVRDALDYIVRHAPCVKPTLVCTDSDELKEFISRPALKFIL
RFLTGLASDHEPTQMLVCEKAIPIVHRLEQVSSGEHVGSLAENLLEALRSQPQCADRVRQ
VREFTRQEKKRLAMAVRERQLGALGMRSNERGQVTAQCSLTQQVADLAEEAGAVCCICRE
GYKYQPTKVLGVYTYTKRCPVEEAEARARKTLGFTTVSHYNIVHVECHMAAVRLQRARDE
WESAALQNASTRCNGLLPLWGPNVPESAFASCLARHTTYLQECTGHRDIGYQCTVHDLKL
LAWRFARGRTFHDDTGGGGPLSNMQLLPALLHMALYVMNTTRMAAREANAVEEFLSWAPV
KRLESAHEAEGALYYATLALLVCPPAEWRRRRVEFLRRLLITGQARSVSGGVQLHALSPE
WRVPRPWADLKAFAVFAALVDRLYGVMFKNVSAATAEQWPVKLAEYIRVSDEANAKAAER
IVATLTDELLPCTSFAEFCDAAGLLEDIPDPDAFLSTLFDEL
NT seq
15609 nt
NT seq
+upstream
nt +downstream
nt
atgattactcagtttctcactgtattctcgaaaatggccgcctctggtggatctatagaa
tggtctactaatgttaaacctattttaacagcactttatggaccctttttcgacaaaaac
gatgcagtagaaataatacaagctattataaaaagtgaaaatgaatttcagaagcatgaa
gaagcatacgacttgttttacacatgttttgcttgcctctcagctcattttatcagcatt
aatgccaataacatacctccagatcagttaagcacagctcaagatgcttttcggattatc
cttcaacaaatcctcaagaaattgtctgaagctgggcagagccaggaagatacttctaat
acgcttagccccaatgtgtctgtcaagcagctgctattgccaattgtggccttatgtggt
attgacagcaacggttatcccccttcggatcttgttattttgcttgcacttcttaagacg
gctaagctaccacctcatggaaacacaaatgaaaatcaaacaacaaagtctgcaatatca
agtcccataacatctctcgcatcaaacacatctacatctgagaagcaaccgccaacaaat
gctcaaaggcgatctgatgcactgctggaacggctgactatgccacttcgcagtcaagta
tcaaatgtattgcctccagctccatctgccatcggagtcatgtcaccggcaagcaaagac
agtattgagtgtgctaaggatggaaatgctcaactgtcttccattgacataaaaaagtgg
gtggcatctacgtgcgcttcgcttctgatggagctgcgagcgggatccacaatattggcc
atctgttcaacgctaccttgcctgcagcgatacttgaaccgctggcaaactgccaaggaa
tccgattcggcaccgtcgttccattcggatgccgcgctgctgtacttcctggtgaacgag
gtggaggtgtgtcgcctggcgctgtccctgccttgtctggagcccttcagtccggagcga
atcgtcactctcagtgacgtcagcgcctcttggctcctctgcgctaccgcacaggccacc
ctccaccagaaggacgaagagggcgaggcgcagacggcgacgatcgtggagaccgcgctc
aacctctacagcaccgtgggagacatcttcaagcagtccacgcgtgccggaggatacgtg
taccaaaatcacttgatgatcggggcgtgggtgctcgtctgcggtctgcaccacgcgctg
ggaggcgcgccgggacccaccccgccgggcaagagtcccgccaaaacgcctctcagaccc
tacaatttgaccaagatgcagcagagcctgggcgtggtgtgggtggcgctgggcggacgc
tgtctctcgtggctcggcgacctgctgtccgacgcccgcctcgaggcgctgagctcgagc
tcggacggccccgcgagcaccccggcctcgctccacatctcgacccaccactcggcgcat
cagagggagctgaggctggccctcgccgctcctctgcaccagttgttggtgaccctcggc
gtagtgtgctaccgcaaggcgacgaacctcaagcgcgccgtggtgccgaaggaccgggac
gccgaagccgaccgctccgagggcgccgccttcttcagggacatgcgactctgctcggag
gactccgagaccgacgacgatgacagcgaaccgctgttcggcctctggttcgagtcgacg
ctggtggcgcccgacgccgacgacgacgggctgacccgcctcggcgccgccgcagtcgcc
tcggcggcgcccgactcggccgagcggggcatcgtgcccgacaaggccgagccgtactcg
tacatatcgctcgcgaccgacgtgttcaccctcttgaccgacgggatagtcggcggcggc
ttcgagcgcctcggccgctacgctctgcagctgcacgaggcccaccacgccctgttggcg
gcgttggctcgagacctggacagggagagcgccaggaccgacacgggaacgatctcgccg
tgtttcggcgcccgactgggcgctctctactcgtcgttcagctcggcgctggtgcgatac
ctgcacgccctgagcggttccccgactttcgccgcgctgaggccgtcgctgcagcagcaa
ctcgcgtccgcggagcgacccaacaccgttccattgcaggtcgggccgcgcgtggtgaag
ctactcggcggcatggtgctgagcaagccggcttcggagagagagaacagtatcctggtg
atgtggcacaacctcatcaataccctgcaagagtacgccctgcagccgctgccctcgcag
gaccacgactacgaagatctcaacgtcgaacacgctcagctcatggtgtacttgtttcac
tcgttgacgctgatgcagaagaagtccgttctgctctccaccgccaacgccatcattaag
gtggtggaaacgctgggcataaacgaaagacagcgcgcgacgaccctggctccgcaccgg
ctgacgctctcgaccaggctgatgctgcttctggagtacctcatgaaacatttgtacgac
gccccgcagacactgctgcagcagatcgagtggaacctcgtagtcgccaccggcctggcc
cggccatcggcggagacgtctctcggcgaagtcggaaccggctccgacgccggcccgccg
aagacgcgcatctactgcgaagtgcccttcgtcgagcagacctaccggaggctgtcgcag
gacgagacctcgatgagacccaagttctacgcgctgaccgacaccaaagtcaacaaccag
gagaatccgaagttcgacggtctggcctgcaatttcgtgctcggcacgccgcacaagctg
aagtatccggtgctggtggacgccctcctggccctgctcaactgcgcctgcgtctgcgac
ggtcggagcaatcgcacctcggtggccgcccgcgccgcggcgcactactgcttccagacc
gcctggaggctcgtgacgagcatgcccccggcaactccgcacatggacaaactgcaggcc
gggacggcggccgacctgccttcgcctctgccgctgtacgcgctggtgtgggctccccgc
gccgacgccaagaaggcgttcaacccctggctcaaggacgcgctcgtcaaacagggcatg
tacacgcagtacgccgaaaaccttctggccggagtgagctcgtcgtgcgacaacatcaaa
tactcggcctggctggcctcggagaccgttaagcacctgaaggagaacctccgagacggc
ctgccggctctcctcgacgtgatgtcttgcgatgcggcgttgatgcggctcaagatgtgc
ctggtggaaacttcctccccgcccgaggcgcaccccttcgtgccgcatctgctgcggctg
ctggagaccgtcctggcgtgtcgcaggtcgtgcgcgagccccgaaggcggcggctccgcg
gggccggcgacggaggtggtgctgagcgtgtgcggcggcgtcccgagcgcgggcgccgcg
tctccgccccgactggggccggcgctgaaggcgctgctgccgagcgacgtggccgcgctg
ctcgactcccgctccgtggatccggcttcgtcggtcgcgccgtccgagagcgccgtgctc
gagctggtctccgcgcactgcgagctgatgagcgacaggctcgagtacggcatcgggacg
tctctgacgatgctggctcgctcggccgccagactcctggagatcggcgccgccgagatc
gccgacagcctggagttgacgaggaagacgctggcgctcatcgtcccggctctgaccgac
ggacgcctcgagttcctagcggagccgttgacggccaccctcaactcgatcgtgcctcag
gccgtcaaggcggaggagatcatacacgagcacattctgcgaaccacgtaccccgcgctc
tgcgactacagcccctccgcggaggggatgctcgagcacatcgtgaggtattgggagaag
atcctggatcggcaggccggtcgcgccgcttacgaggcggtgttcgtcgaaggagacggc
gagttcgtgctggggagaatccttctgtcggcgcccagcaccagcaatcctttcaccgat
cgcgtcgtcaagctgttcactaaaatatttgccagctgcgaatcagaagacgtgagccaa
agcctgtgcgtcggagtgtgcaagttcatcggcgtcgccgaccgacagaccttgttcgac
cttctcggccacatctgcatttacggaccgtccctcgcgactgccggcacggcgaacggc
agtcccaccgagacggaactccctactccgacgtgctccgctcccgaaggccatcccgcc
tcgctcgccctgcgcaacgccatccgctgcgtgctcttccgcaccgatggcgaagtcgcc
ccgcgcccggacgcccgcaacgagcgcgacctgcccgtcttcgacaatcctgtcgcggcg
actccggctccgggggctcaatcggagacaaacgcccaacaatctggaaattcagagacg
tgcagctggtcggactgcagcaaggacagcgccggggcaaccggggggggcgcggcggcg
tcccgcgtcgaggcgagttcgcccgtgggtgagggcgcccacgccgcccttctaacggct
ctctgcaagcacgtcgtactgcactgcgaagaggaggcgagcgagcgcctgctggtgact
ctgatcgaagtcagcggcgagggctgtcctcctccgctgcttcgagagatgtgccgtctc
gcggactcgcactcgggcacgctgcacgagctactctttccggccgcgctggcgtggctc
tcctcctgcgtcgaaagtctcggcagccccgaggtgctggagaagttagaggagggcacg
atcgacaacgacaagacgacgcagcagatagagtccgcgtgtacgttgctgtcgtacttg
ggtgacgccttgcacgccatcggcgccccgccctcgcacgcgtggcgatcggtcagcccg
acgtgggaatctccttccgacctcggcttcgacttggactacgccgacgaacaacaggac
gatgacgacacgagcgccgacgattccgacgaggacgccgtgctgaccaacaagctgtgc
accttcacgataacgcaacgcgagttcatgaaccagcactggtaccactgccacacgtgc
aagatggtggacggcgtcggagtgtgcacggtctgcgcgagggtgtgccaccgcggtcac
gacatctcctacgccaagttcggaaacttcttctgcgactgcggagccaagccggacttc
agctgccaagccctggtgaagcgcgagaaatcttcgggcggcggccgaacggccgaggag
gcgcccccggcgccgtccctgcgccgtcgcccatccagcccaacgcccgccgccctgctg
tccccgccgaggaggcccgtgctggctcataacattcagggttgccgaagcttcctggcg
agctacggaaagtgggagtggtgcctcgagcgcgtgcgcacgctgctgtgcgcgctggcg
ggccccgtgcgcgctgcgtgcgagcgaacggccgcggtcggagcgcacggccgggcgcag
agggcgctggcgcaactccacctgggcgagaagaagttctcgcacacggactcgctaatg
ctgcccaccctaggttctcaagaaggcgccttcgaaaacgtgcgaatgtcgtacacggga
gagaacggtcagaccatcaggcagctgatatcggcgcacaagctgcgtcgcgtggccatg
tgctgtttggcttcgccgcagggccgaaggcagcacctggccgtttcgcacgagaaaggc
aaaataacggtgctccagctgtcggccctcctgaagcaggcggactcgtcgaagcaccgg
ctgaccctgacgcggctgtcttcggccccgatcccgttcaccgtgctcagcctgagcggg
aacgcggccaacgaggacctcttggccgtgtgcggactcaaagagtgccacgtgctcacc
ttcaactctggcggagccgtggcggatcatctggtcctgacgaccgacctggaggcgaac
aactacataattaaagccatctggctgccgggctcccagacgcagctcgcgctcgtcact
tcgaacttcgtcaagatattcgatctcagcaaggacctcgacagtcccacgcattacttc
ctcgtgcccagcggaaaggtccgcgacgtgacgttcgtgaaccaagagggcgtgatgaac
atgctctgcatgagctcggcgggtcacatctactggcagccgctgagtgaagagtctctg
gcgacactcggcactttctacgtcaccaacaccttggaagtgttgcacccggagatacag
gacgtcgcgggactggtgggcggaggtggagtttctatttactactcgcacactctgaag
atgctcttcttctcgtacgctcagggcaagagcttcctcgccccgctcaactcggtcgaa
gagagcgtcaaaggcaccgccatgatcaccgtctacggcggagggggtggccccaaagag
ggcgggcgcggcaagggcggcgcgcagtctctgctgcagtgggccgaagtgcccggacat
ccgggcctgctaacggctctcatgcaggcctccaacaaccccgtcgtgctcatgctcacg
ccgtccggcattcacgtgcaagagatcaaggtggtgccggccaaggcgaagatcaccgac
atggtggccgtgcggcactggtgcggcgccggcgagcagaagagcacgttgattctcctg
tgcgaggacggtagcctgcgcatgtacgccgccgatcccgcccggacgggcttctggctc
tccggcgccgtgcagcccgtgcacgcgccgcgcagacgcgcccgccccgcgaggccctcg
cacgcacacgccgtgccccgaaaacagcaccagccgacgccgaagacgagcgacggagct
ccccagttcccgatagacttcttcgagcactgccacgagatgagggacgccgagttcggc
ggcaacgacctcctgcaggtctacaacacggcgcagatcaagcatcggctgaacaccacc
ggcctctacgtcgtgtcgaccaagatgagcggcttcacaatggaagtcaccaactccgac
ccgaactcggtcatctgcggaattcgggtcttgctcggcagccaggacgtcgccaggacg
ccgacttacgtcgaaatctacgggagagcagtcccgactatggtggttcgcaatcgatgg
ttcgacgttcctctctcgagagaggagtcgctgcagtccgacaaaaagctctgcatcgtc
ttcgggccctcgcaagatccggacggcgtcaccatggtggattccgtcaagatctacgga
aagaacaaggagcagttcggttggccggaggagaacgaagacccggccgcctgtcagtct
tccggcagagtgcctcaggaagccgagggcgcgacgggcggcggcgacgggcccggtgcc
gtggagcgtctggcgtgctcggctctggaggcgctggagctgagcgccggcgcggccgtc
cgctcgggcgccgcggcgggggccgacgccgccgcggacgccgccgagagcctgctgtgc
gtgcccgcctcgccgacgctgcacgcgagagcccagtgcctcctccgcgccgtctaccag
ggcgactatcatcagcgcaaggaccgggccgtcctgcggtacgtgtgcgcctccctgcgg
gagctgcgcgacgcgacggacgcccgcaacgtggaccccgaggcgtacttccgcctcgtg
ctgctcgcccgctccgtggccgtcgcgcgtccgcacaacttggtccgattcacgcctccg
acgcccgggaagcccgccgacggcgactggtccgccctgtggaaggcagacgggtcgggc
gacgagccgcacgcgtgcgctttgctcgtgagcgtgctctggaagttggcggcctgcagg
agccaggcgcgaggcccccccggcatcctgtcttacggcctcaggcacaccgagcacacg
ctgcacgccctggccgacatcatacacgccttccaactcaactccgacccggagtgtgtc
gaattcggcaatcaaatctatctgtcgctcctcctcgccgaagaccagaacatcagcttc
ggcgcgaaggcggctctcgtgcgagtgctgcgacctcgggtgaagaggcgacgcgtctac
attccgtctccgccgaacacaccgggagccggctcgtcgacgaacgcgggtcgcgcgagc
ggctcggcgtccgaggtcgcggcttcggagcccgaactcggcgctcggcgggaacctcga
tacgtggacgtcgacgactcgctcgaaccgatggtgctgctcgcgcccgacggaggtctc
gaggcgctgctcgacattccggccgatgcggacgacgagacaatggtggagctggccatc
gcgctgtcgctgcaagagcaggaacagccgcggagacagcagccgcacacgcccacggcg
ccgccgccgccggcgcccggcttcagcgacgccaatgcctcgccaaacggctcggacgac
gaaggcagcactgcggcgacggacggcagcaccctgcggacgtcgccggccgaggccgcg
gggtcggccggcgaggagagcggcggttccggcgccgacagcatcggtggagtttccggc
cgcagcagcgtctacgccgggccttcgacttcgtcgtcgcagccggtggcgtcctcgtcc
cgcggcctcgaagcggagagcgagacgcgcaaactccacgcgctgcgcctgtctctgctg
tccgccgcgctggatgctctgccgtccctcaggaacttacctggagtcagagccattccg
tttgtgcaagtggtgctgatgctagccggtgacttggattccagcgtcgaaggtgacaga
gcgctcctggatctcctgctggaggttctgatcggcgagctggacattcagagcgaggag
ccctccgtcgaagatcgagatgcgagacgagatttccagttggccatcgccaggttggag
acactggtctcggaaccggacaccgcggacgaaagcaccccgcccgtctacgagaggacc
aatcgcagagagctgcagctcgtcatcatgagactgttgagcgtgctcatgagccgctgg
aagacgtgcgggtcccgcgagcacgcgctgagcacgtcgtgcgcggcgcacgtgtcgcga
ttggccgcggccgccttcgtgcgcgccggcgcccccggccactgctacggcgtgctggct
gcgctgctgccctactggcggcagaagagcaacagcaacgcggccgccacgactcctacg
cgacagcttctcaaacctcaaccgccgcagccgctgcccgacatgcagccgttcttcgtc
aaggagtacgtcaagagtcacgtcctggacgtattcgataactacccgcagcttttgatg
gaaatggcggttcgtcttccgtaccagatccacaagcactgcgatccctcgcatttcgat
tcccgatggcgcactcttctctgcgagtacatgatgaatcctcagacgcccctcaggaaa
caagtacgcaagctcctgctgctcctgtgcgacactcgggaacgctatcgtcagattcgc
gacgtgcacgccctcgacacgcacttgaacgccgcgcgggcgctgctggccacggacccg
gcctacgacaagctcgttcggctcatggagcatctcaaggcgtgcgtggagatcgtgacc
cctcgcacgggcaactggcagcacgcgtgccgctcggagcggcgcgagaccctgccgtgg
ctgctgggtgccgccagacgcctgcacccgcacgtggcgcccacggtgctacagctgctg
caggcggctctgtgcccgcccggcgctcagcccgctgcccaaccgacccaggccggcgcc
aaagatgccaaggcgcagcccgagtggcctaagcgcgagcgcagcgccgacagcgacggc
tacgtgtcggacgcctccaagtttcaagagcagagagtgcccgacctcgtggcccagata
cacaaacaggtgtctcaagaagaattgaaactgttcgtgaaggccttccttctggagacg
aattcgactgcggttcggtggcaagcgcacgcgttgctgttggccatttacaacaactcc
tctccgaataaacaagcatctctggtggcgctgctctggagtctgtggcccacgctgccg
cagtacggacgcaaagcggcgcagttcgtcgacctgctcggctacttcacgctgaagacg
tcgaaggtcgacagctcggagtacatcggcagcgcggtggacctcctgcgcaaccagaac
cgtctgttgacgtcccacgggaactcggctctgtacgcgtctctgggagcgtacgtggag
ctcgagggctactacctggagtcggagccctgtctcgtgtgcaacaacccggaagtgccc
atggccaccatcaagctgcccacgataaagatcgactccaagttcacgacgacgacgcag
atcgtgaagctcgtgagcagccacacgatcagccgcatcagcctgcgcgtcggagacatc
aagcggagcaagatggtgcgcggcatcaacttctactacaacaaccgcaccgtgcaggcc
gtgcaagagctgaagaacaaacctggcatgtggcacaaggccaagcgcgtccagttgcaa
tccggacagaccgaagtgcgggtggatttcccgctgccgatagtcgcctgcaacctcatg
atggagtacgccgacttctacgagaaccagcaggccaccggtgaatctcttcagtgtcct
cgctgctcgcagtcggtgcccgccaatcccggggtttgcgccaattgtggcgaaaacgtc
ttccaatgtcacaagtgccgggcaataaactatgacgagaaagatccgttcttgtgtcac
gcgtgcggcttctgcaagtacgccaagttcgactacactctgatcgcgagaccctgctgc
gtcgtcgattccatcgagaacgatgaggagcggaagaagaccgtgcagacaatcggcact
ctgttggacaaggccgaccgcgtctaccgccagctgatcgccaacaagccccaattggag
tcgctggtgcacaagataagcgagcaccgcgtggacggtcggccggacgagaacagcaat
acggcgaccgcggccctgggagggggtcaggtcaaccgcgtcatccaggcgctcgcgcac
aagtactgcgtcgagagcaaggggcacttcgaggacctctccaagatcatccagaaggtg
ctggcctgcaggaaagaattggtcgcgtacgacaaagctcagagcgaacggcaaaacggc
gaggcgtcgcccgcgtactccgtgctcgcgcagaactacgacggcgacctcgccaaggag
agcggcggctcgtgctacgggtgctcgctgtgtacggcggagcactgcctgaccctgctg
cgggcgctggcgtcgcagcctgacaagagagccgccctgtgcggcgccggcctcgtgcac
gagctcgtgcatcacaatctgcaccgcggcacgccgcagagccaggaagaggtgcgcgcc
ttgatctgcctggtgacgcgtgacaacttggcggcgacggaacgcctgtgcactctgctg
acgcagcgcatcactctgtcgctcgtgggacacgccgcctcgcaggaccacaacaactcc
gtgcggcctctggttctcctcctgggatcgctggtcaaggtccaggactcgatcgaatgt
tgggaggtgaggctccgatgcgtcgtgaagctgtgggtctggtgctgcccgaaagtgagc
gaagtggcagggatcccgccggccgcccactacatcctcaaggacgaggcgttggccgac
atgcccggcatcaacacctgctcgcccaactctcaccaattcgccctccaacaagtggcc
ctgccttgcctccgctacatgcaagagctgatggctccactcgtcgccacgccgtctccc
gccccgtccgccctctcagccgcggccactgcgaccaccgcgacggacgacctagtcgag
gaagtcaaggagggagacgagccgcataatcggacgggcgacctcgtcgtcgacctggcg
gcgtggctggccggccgagtgtcgcagaaggagtggcgtagcctggccgccccggaagcc
gcgccgcccgccgactgcgagcttccgccgagggacctgcgcctggcgcgcgagtccgtc
ggccgttggaggcgccgggtgctgctcggccgcggcatgcggcgtgtcagcctatcggac
ggtggctggctgcgccccgtcatgttcgaccccagctcccgcatcgcgagagacaccgcc
tgccgagtcgtcgcctcgctctgcgactcctacgagcggaccaaggcggtgctgatcctg
ttgacgagcttcctgcccgaagtgggtgcggcgggggaggcgagcgagcagttccttcag
ctgtatcagcgtctagccgcgaagagcccgtggaagcagttcctggcgctgcggggcgtg
ctgcagcagatagcggatctcatgactgacgagatcgagcagctgcaccgcctcgaggag
accacgctcacctcggacctcgctcaaggatacgctcttcaacgtctcacggagttgttg
gcgatgttcctggaggagccgggggctcggagggcgtacaaaggccggctggtgggagcc
gtcctcgggggctacctctctctgcgtaggctggtggtgcagaggacgcgcctcacggac
gacacgcaggagaagctgctggagctcctcgaggagatgaccaccggcaccgaagcggag
acggccgagttcatggcggtgtgcatagagaccgtgcagaagtacccgctgcacgattac
cgcactccggtgttcatcttcgaacggctctgctccatcatctacccggaagaaaacgac
gtcggcgaattcttcctcactctggagaaggatccgcagcaggaggacttcttgcagggc
cgcatgttgggcaacccgtattcgtcggcggagccgggcatgggccctctgatgcgcgat
gtcaaaaacaaaatctgcacggactgcgagctcgtggctctgctagaagatgacaacggc
atggagttgctcgtctgcaacaagatcatgtccctggacctgcccgtcaaggatgtcttc
aagaaggtgtggtgcaccctgggagagagtctggaagcgatgcgcgtcgtgtaccgtatg
agaggccttctcggagacgccaccgaagagttcgtggagacgctcagccagaccaacgcc
gaagccgtcgacgacgagcagacgtaccgcatggccaacgtgctggcggactgcggcggc
ctggaggcgatgctgcggcgcttggcggcgatccagcgagtgggcggcgcgcgagccctc
gtgtcgaccctgctgcgcctgctgagtctgtgtgtgcgtgtgcgccgttgcgtgcgcgtg
ctgacgagcaccgaaacgcgcgctctgcccgtcctcttgcacgcgctcacgctcgccgcc
gccgaggagaaggacatgcccagggcggagctcgtgcatcaactgctcgagataatggag
cgcatactcacggtggcagccagcgagagcttggagtcgttcctgcagttctcgctcacg
ttcggtggaccggaacacgtgcaggccctgctcaactgtacagaactgacagcgatccgc
aacaattccgtgtctctcggccacctgatgcgcgttctggccgcgctggtctacggcaac
gacctgaagatggcgatgctggtggagcacttcaagccggcgctggagttcgagcgcctc
gacgccgaacagtggggcgagcgcgagttccgcatcgagctgttctgcgcgctctgcgcc
aacatcgagaggaacagcgtcggaggcacgctcaaagactacctgatctcgctcggcgtc
gtccgcgacgccttggactacatcgtgagacacgcgccgtgcgtgaagccgacgctggtc
tgcaccgactcggacgagctgaaggagttcataagtcgaccggctctgaagttcatcctg
cgattcctcacgggcctggcctccgaccacgaaccgactcagatgctggtgtgcgagaag
gcgatcccgatagtgcaccggctcgagcaggtgtcctccggggaacacgtgggctccctg
gccgaaaacctcctcgaggcgctccggtcgcagccgcagtgcgccgacagggtgcggcaa
gtgcgggagttcaccagacaggagaagaagcgcctcgcgatggccgtgcgcgagcggcag
ctgggggcgctgggcatgcgcagcaacgagcgaggccaggtgacggcgcagtgctcgctc
acgcagcaggtggccgacctggccgaggaggcgggcgccgtgtgctgcatttgccgcgag
ggatacaagtaccagcccacgaaggtgctgggcgtctacacctacacgaagcgctgcccc
gtggaggaggccgaggcgcgcgcgcgcaagaccctcggcttcacgacggtctcgcactac
aacatcgtccacgtcgagtgccacatggccgccgtgaggctgcagcgggccagggacgag
tgggagagcgccgccctgcagaacgccagcactcgctgcaacggcctgctaccgctgtgg
ggacccaacgtgcccgagtcggccttcgccagctgcctggcccgacacaccacctacctg
caggagtgcacgggccaccgcgacatcggctaccagtgcacggtgcacgacctgaagctg
ctggcgtggcgcttcgctcgcggccgcacgttccacgatgacacgggaggcggaggtccg
ctctccaacatgcagctgctgccggcgctgctgcacatggcgctctacgttatgaacacc
acccgcatggcggcccgcgaggccaacgccgtggaagagttcctgtcctgggcgccggtc
aagcgcctcgagtcggcccacgaggcggagggcgccctctactacgcgacgctcgccctg
ctggtctgcccgcccgccgagtggaggcgccgccgcgtggagtttctgcgtcgcttgctg
atcacgggacaggctcggagcgtgtcgggcggcgtgcagctgcatgcgctgtcgccggag
tggcgcgtcccgaggccctgggccgacctcaaggccttcgccgtgttcgccgccctcgtc
gaccggctctacggggtcatgttcaagaacgtgtcggcggccaccgcggagcagtggccc
gtgaagctggcggagtacatccgagtgagcgacgaggcgaacgcgaaggcggccgagcga
atcgtggcgacgctgaccgacgagctcctgccctgcacctccttcgccgagttctgcgac
gcggccggcctcctcgaggacatccccgaccccgacgcgttcctgtccactctcttcgac
gagctctga
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