Poecilia reticulata (guppy): 103457636 Help Entry 103457636         CDS       T05149                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism pret  Poecilia reticulata (guppy) Pathway pret04020   Calcium signaling pathway pret04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:pret00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     103457636    04020 Calcium signaling pathway     103457636  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pret04040]     103457636 Ion channels [BR:pret04040]  Voltage-gated cation channels   Ryanodine receptor    103457636 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 Motif Other DBs NCBI-GeneID:  103457636 NCBI-ProteinID:  XP_017157612 LinkDB All DBs Position LG21:complement(13183002..13314985) Genome browser AA seq 4733 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQSVATIQKEHRKFCLAAEGLGNRLCYLEPTSEAKYVPP DMCICNFVLEQSLSVRALQEMLANTGASSEGKADHEKWMLIKKAGQGGGHRTLLYGHAIL LRHSFSDMYLTCLKTSRSLTDKLSFDVGLQEDSVGEACWWTIHPASKQRSEGEKVRIGDD LILVSVSTERYLHLSNCNGNIQVDASFMQTLWNVQPTCSSGNMAVGYLIGGHVMRLCHGH DESLTNPGADKSEEEQRIVNYEAGKGASRARSLWRLEPLRISWSGSHIRWGQSFRLRHLS TGHYLALTEDRGLVLEDREKCHTKATAFCFKPSKEKGDSGMKRDIDGMGVPEIKYGDSVC FVMHVATGLWLSYLAPDAKSSRLGPLKRRACLHSEGHMDDGLILQRCQHEESRAARIIRN TTFLFKNFIKALDSAAAGETNAVAGYVEEVLQTLNDLIEYFKQPDVDLEHEEKQARLRSL IKRQDLFKEEGMLALLSKCIDRMNLYDSAAHFGEMAGEEAGAAWKDILNLLYELLAALIR GNRTNCTQFSRNLDWLVSKLERMESSSGILEVLHCILVESPEALNIIQKGHIKSIISLLY KHGRNHKILDVLCSLCVCNGVAVRTNQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLG IAEGSAQYKKWYYELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDL YSYSFDGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDF NTDRFFFPVVSFSAGVKARFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVEPVKEYKR DHDGVRDLLGTTQFLSQASFIPTPVDTSQIVLPPHLENIRDKLAENIHELWGMNKIELGW TYGKVRDDNKRQHPCLVDFSKLPETEKNYNVQMSSETLKTLLALGCHVAQVNVHAEEDLK KIKLPKDYMMSNGYKPAPLELSDVKLTPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQ DVKSRRNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQEVVHALDNQSIET IRFFRVEQTYAVKTGKWYFEFEALTGGDMRVGWARPGCRPDVELGTDDQAYVFDGYRGRR MHAGSRYFGQPWKKGDVVGCMINMEDKSMIFTLNGELLITSKGSELGFADFETEDGFIPV CSLGMSQIGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREITMWFSKRLPTFFNVPQD HMHIEVTRIDGTVDSPPCLKVTHKTFGTQNSNSDMVYCRLSMPVEFYSADRLLDESLKLS QPPKEDGSTDYGSITTYYHSVRVFAGQDPASVWVGWVTPDYHYYSKNFSLSKTQTVTITL GDERGRVHESIQRSNCYMVCAADALGPSSSSRSNTDLEIGCLVDLATGLVSFTANGKELP TVYQVEPNTKLFPAVFCCPTSSNLFQFEFVKIXDAMPLSSAMFRSEQRNPVPQCPPRLDV QTIVAVLWSRMPNTFLNVEAARVSERHGWVVQCLESLQMMAVHIPEENRCLDIMELSEHE DLRTFHSHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYDVLIS IHLETAKEARLMMNNEFIIPVTDETRSIKLFPDESKHHSLPGVGLSTSLKPRVNFSPVGI ISTKRHQLLYSPQIPLGVLKEKAISMLTEAVQGGGSHIRDPVGGSLEYQFVPILKLIGTL LIMGVLTSDEVRLILLLIEPNVFGEAKEGEEGSGGEVVVAGEKEEVSKNEEKAVEAGEEE TKESKPAAKGLLEKSLPESVKHQMCELLHYFCDCELQHRIEAIVSFSDRFVSKLQYNQKF RYNELMLAFNMSAAVTAKKTKEFRSPPHEQVPHFNAFALAGIPVEEEEEEQDTSIKGRLL ALLYKIKGPPQKTEEEPAETEQAAPTNLKELISQTITSWAQESHIQDPELVRVMFSLLRR QYDGIGELLRAMKKSYTISAASVQDAINLLASLGQIRSLLSVRMGKEEEKLMIDGLGDIM NNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPKMVASCCRFLCYFCRISRQN QKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNNGLALALEEPDLEKVVTYLA GCGLQSCAILVAKGYPDLGWNPIEGERYLSFLRFVVFCNGEAGHFGIIISKIYNAAGMKE LKTQLHTKTTAKRSCERGQKVDPRLXFVCCRSGEEEGEVIHMGNAIMSFYSALIDLLGRC APEMHLINAGKGEALRIRAILRSLVPTSDLVGIISIPLKMPVINKDGSVTEPDMSACFCP DHKAPMVLFLDRVYGIEDQSFLLQMLEVGFLPDLKASASLDTVSPKEPSSNSQLLSSLIV CRHLRPSMMQQLLRRLVFDVPLLTEYCKMPLRLLTNHYEQNWKYYCLPSGMGGFGMASEE ELLLTKKLFWGIFDSLSQKKYDSELFKMAKSCLCAIAGALPPDFVDTSLGAMVEKQESVD AQGNFEPKPINTANISLPEKLDYIANKYAEHSHDKWASEKMSAGWKHGDSLDEQAKAHPL LKPYKSLSEKERETYRWPVKESLKSMLAMNWNIERTKEGEAMFQQRESEKQRKLSETQSN GFSPAPMDLHNVTLSRELQSMVEVVAENYHNIWAKKKKSELLSKGGGLAHPLLVPYDTLT AKEKYRDKEKAQELFKFLQISGYAITRGLKDMEQDSSSMEKRFAYKFLKRLLKNIDSAQE FIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPMIDQTFKNHCLYFLSTPSKNLSSCGCAS NKEKEMVTSLFCKMAALVRHRISLFGSDSAIMVSCLHILSHSLDTRTVMKSGAELVKVGF KAFFENAAEDLEKLVEMLKLGKFMQSRAQMKSVTQSINYVTVALLPILTALFEHITTHEF DVDLLVDDVQLSCYRILMCFYSLGTGKNVFVERHLPAIGESLATLVGAMPVAFLEPHLNA HNPLSVFNTKTPRERAILSMPDTVEEMCPEMPRLDKLLKDVNDVSESGARYSDMPQVIEV VLPMLCNYLSYWWEKGPENSPPDSDCCTMVTSEHLSIILGNILKILNNNLGIDDAPWMKR IAVYSQPIICKAGADLLRTHFLPTMEKLKKKTVKVVSEEELLKADGKGDNQEAELLILDE FAVLCRDLYAFYPMLIRYVDNNRSRWLKEPDADSTELFRMVAEIFILWCKSNNFKREEQN FVIQNEINNLGFLTGEGKSKMSKSGGDQERKHKRRRGEYYSIQTSLIVAALKKLLPIGLN MCTPGDQELISLAKIRYSLKDTDDEVKEHLRQNLHLQEKSDDPAVHWQLNLYKDVVVKSE EPSDSEHTVERIQSISAAVFNLEQVEQPLRNKKCXVQKLLSKQRKRAVVACFRMAPLYNL PRHRAINFFIPAYERLWIEAEEYSFEEKLVQDLAKTPMKIVEEEEEEEAEIKPDPLHQLI LHFSHNALTERSYLEVDPLYIAYADMMAKSCAEDEEEEEEEGREKTFEEKEMEKQKILYQ QARLHARGAAEMVLQMISASKGRLGPMVTCTLKLGISILNGGNVQVQQKMLGYLTDKRDA GFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTQEGSSSKVLQNDEFTKDLFRFLQLLC EGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVIDETGKHNFS KALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDASQIEL LKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLT TSDNFKEYDPECKGIISKKEFQKSMESQKQYNQSEIEFLLSCAEADENDMFNYKEFVERF HEPAKDIGFNVAVLLTNLSEHMPHDARLATFLDLAESVLSYFEPYLGRIEILGSAKRIER VYFEISESSREQWEKPQVKESKRQFIFDVVNEGGESEKMEMFVNFCEDTIFEMQLASQIS EPDAVEQPEEEEEEEVHSILEELSGGDDAALESASAFTTACRSVKKNLSEIRQIFTIKTA RKQXKKIKKLSIKELITGFFSFLWMIFIGFFKGIFSLVFGFFHVIWSSMFGGGLVEGAKN IKVTDILGNMPDPTQFGIHGDVGEGDKVEAMESSGSLDKAMAPAGDATEVDVMLEMLAPK KEGGKHVEPGLGDVSELSGESSAADSKKKAAAKTAAPSESETEKADTETREKEDKPKEEE AKEPAVEEKPKPKSSQPKEASPAFMSTVFAILDVYLNKILNYLARNFYNLRFLALFVCFA INFILLFYKVTGEAEEEEEGDEENSWGDDDGENTLFDMDEFVLQESTGYMLPTLRFLAIF HTVISLLCLFGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVINTP SFPNNYWDKFIKRKVINKYGDMYGAERIAELLGLDKSALDFDPTVETVEKEASLLSWLSS IDTKYHIWKLGVVLTDNYFLYLIWYTTMSIFGHFNNFFFAAHLLDIAMGFKTLRTILSSV THNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVG VRAGGGIGDELEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQV KEDMEVRLXSRLQPNVSRFLFQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14202 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaggatgagatccagttcttgagaactgacgatgaggtg gtgctccagagcgtggccaccatccagaaggagcatcgcaagttctgcctggccgcggag ggactcggaaaccgcctgtgttacttggaacccacctctgaagccaagtatgttcctcca gacatgtgcatttgtaactttgtgctggagcagtcgctgtcggtccgcgccctgcaggag atgctggctaacaccggagcgagcagcgaagggaaagccgaccatgaaaaatggatgtta attaaaaaggcgggtcagggaggcggacaccggaccctgctctacggtcacgccatcctc ttacgtcactccttcagtgacatgtacttgacctgtttgaagacatcaaggtctctgaca gacaagctgtcatttgatgtcggactgcaagaagattcagtaggagaagcctgctggtgg acgattcatccggcgtccaagcagagatcggaaggagagaaagtccgcataggagatgat ctgattctcgtcagcgtgtccactgagagatatctgcatctctcgaactgtaacggcaac attcaggtagacgcctccttcatgcagaccctctggaacgtccagcctacgtgttcgtca ggcaacatggctgtagggtatttgattggcgggcatgtgatgcgtctctgtcatggtcac gacgagagcttgacgaaccctggagcagataagagtgaagaggagcaaagaatagtgaac tacgaggcggggaagggagcgtcaagagcccgctccctgtggagactggagcctctcagg atcagctggagcggcagccatattcgatggggccagtctttccgcctgcgtcatctctcc actggtcactatctggccttgactgaagaccgtggtttggttctggaggacagagagaag tgccacaccaaagccactgctttttgctttaagccatccaaggaaaaaggcgattctggc atgaagagggatattgacgggatgggagtccccgagataaagtatggtgactccgtctgt tttgtcatgcacgtggccaccggactgtggctgtcctacctggcgcctgatgccaaatcg tctcgtcttggtcccctgaaaagaagggcctgccttcactctgagggccacatggatgat ggtctcatcctacagcgctgccagcatgaggagtctcgggctgctcgcatcatccgaaac accacattcctcttcaaaaacttcataaaggcactggacagcgctgcagccggagagacg aatgcggtggccggatatgttgaagaggtgctgcagacgctgaacgatctgattgaatat ttcaagcagcccgacgtagatctggagcacgaggaaaaacaggcgaggcttcgctcgctc atcaaacgacaagacctcttcaaggaggagggtatgctggccctgctctccaaatgcatt gaccggatgaacctgtatgatagtgcggcccacttcggagagatggccggggaggaagct ggtgcagcatggaaggacatcctcaacctcctctatgaactcctggctgcactgattcgt ggaaaccggaccaactgcacccagttctcccgaaacctggactggctggtcagcaaactg gaaagaatggagtcatcatcaggaatcctagaagtcctccactgtatcttggtggaaagt ccagaagccctgaacatcattcagaaaggtcacattaaatcyatcatctctcttctctac aagcatggacgcaaccacaagattctggatgtgctgtgctctctgtgtgtgtgcaatggg gtggcagtgagaaccaatcagaatctgatctgtgacaacctgctgccaaaaagggacctg ctgctccagacmcgactggtcaacgatgttcaaagcatgaggcccaacatcttcctgggc atcgctgaaggttcggctcagtataagaagtggtactacgagttggtcatcgaccaggtg gaccactttgtgaccggagagccgacccacctgagagtgggctgggccaacaccaaaggc tacgctccgtatcccggcggaggagagggctggggtggaaacggcgttggggatgacctt tactcctacagctttgatggacttcatctgtggtcaggtcggatccccagagccgtggcc tccattaaccagcacctgctgaactcggacgacgtggtcagttgctgcttggatttgggc gctcccagcatgtccttcaggatcaacgggcagccggtgcaggggatgtttgaggacttt aacaccgacagattcttcttccccgtcgtcagcttctctgctggagtgaaagcccgtttc ctgctgggtgggcgccacggagactttaagttcctgccgccagccggttactctccgtgc tacgaagcgctcctgcccaaggagaagatgcatgtggagcctgtgaaggagtacaagcgg gaccatgacggcgtccgtgacctgctgggaaccacccagttcctgtcccaggcctccttt attcccactccggttgacaccagccagattgtcctgccgcctcatctggagaacatycgc gacaagttggcagaaaacatccacgaactttggggaatgaataagatcgaactgggctgg acgtatggsaaggttcgtgacgacaacaagaggcagcacccttgtcttgtggatttcagc aagctgcctgaaactgaaaagaactacaacgtgcagatgtcaagcgaaacacttaagacg ctgttggcactcggctgccatgttgcccaggttaatgttcacgctgaagaggacctgaag aaaatcaaattaccaaaagactacatgatgtctaatggatacaagcctgcgccrctggaa ctctctgacgtgaaactgactccaggtcaagaggttctggttgataaactggcygaaaac gcacacaaygtttgggccaaagacagaatcaaacaaggatggacctatggcatccagcag gatgtgaagagcagacgtaaccctcgcttggtgccatatgctttattggatgaacgcaca aagaaatctaacagagacagtctgagagaggccattcggacgatggttggatacggatat gacatcgaccctccagaccaggaggttgtgcatgcattagataatcagagcatcgagaca atccgctttttccgcgtggagcaaacgtacgccgtgaagaccgggaagtggtactttgag tttgaggccctgaccggaggcgacatgagggtcggctgggccaggccgggctgcaggccc gacgtggagctgggaacggatgaccaggcctacgtctttgatggatataggggtcgacgg atgcatgctggtagccgttactttgggcagccttggaagaagggcgacgtggttggttgc atgatcaacatggaggacaaatccatgattttcactctgaacggagagctcctgatcacc agcaagggctctgagctcggcttcgctgactttgaaacagaggatggttttattccggtg tgcagcctcgggatgtctcagatcggccgcatgaacctcggaaaggacgccagcacgttt aagtactacaccatgtgtggcctccaggagggcttcgagccctttgctgtcaacatgaac agggagataaccatgtggttcagcaagcgtttgcccacctttttcaacgtaccccaggac cacatgcacatcgaggttaccaggattgacgggacagtggacagccccccgtgtctcaag gtcacacataagacgtttggcacccagaacagcaacagcgacatggtttactgcaggctg agcatgccggtggagttctactctgcagacaggctgctggacgagtcgctgaagctcagc caacctcccaaagaagatggaagtactgactatggaagcatcacaacttactaccactcg gtgagagtgtttgccggacaggacccggccagcgtgtgggtkggctgggtcacaccagac tatcactactacagcaagaacttcagtctcagcaagacgcaaaccgtcaccatcaccctg ggagacgagcggggccgggtccacgagagtatccagaggagcaactgctacatggtgtgt gcagcagatgcactcggcccgtcttcctccagccgctcaaacaccgacctggaaatcggc tgtctggtcgacttggccaccggcctcgtctccttcaccgccaacggcaaagaactgcct acagtgtatcaggtggagccgaacaccaagctgttcccggctgtgttttgctgccccacc agttccaacctcttccagtttgaatttgtcaaaatamaggatgccatgccgctgtcgtca gccatgttcagaagcgagcagcggaacccggttcctcagtgtccaccgcgtctggatgtg caaaccatcgtggccgtgctttggagccggatgccaaacaccttcctaaacgtggaggcg gctcgggtcagtgagcggcacggctgggtggtgcagtgtctggagtctctgcagatgatg gccgtgcacatacctgaggagaacaggtgtttggacatcatggagctgtcggagcatgaa gacctgaggacgtttcactcccacactctgaagttgtactgcgccctctgcgctctggga aacacgcgtgtggctcacgctctctgcagccacttagaccaatcacagcttctctacacc atcgacaaccagtacctgtcgggcatgctcagagaaggcttctacgacgtcctcatcagc attcatctagagacggcgaaagaggcacggctaatgatgaacaacgaattcatcatccct gtgacggacgagacccggtccatcaagctgttcccggatgaatccaagcaccattctctt cccggagtcggcctgagcacttccctcaaaccccgggtyaacttctccccggtcggcatc atcagcaccaaacgccaccagctcctctacagcccccagatccccctgggcgtcctgaag gagaaagccatcagcatgctgacggaggccgtgcagggaggaggctcccacatccgagac ccggtaggcgggagcctagagtaccagttcgtccccatcctgaagctcatcggaacgctg ctcatcatgggggtgctgaccagcgacgaggtgaggctgattctcctcctcatygagccc aacgtktttggggaggccaaggagggagaagaggggagcgggggcgaggtggtggtggcg ggggagaaagaggaggtgagcaagaacgaggagaaggctgtggaggcgggagaggaggag accaaggagagcaaaccggccgccaaaggtctgctggagaagtccctgccggagtctgtt aaacaccagatgtgcgagctgctgcactacttctgcgactgcgagctgcagcaccgtatc gaggccatcgtctccttctccgaccgcttcgtctccaaactgcagtacaaccagaagttt cgctacaacgagctgatgctggctttcaacatgtccgccgccgtcacggccaagaagacc aaggagtttcgctcgccgccacatgagcaggtgccgcactttaacgcatttgccctggca ggaatccccgtggaggaggaggaggaagagcaggacacatcgattaaaggtcggctcctg gctctgctctacaagatcaagggcccgcctcagaagacagaggaggagcccgcagagaca gaacaggccgccccgaccaacctgaaggagctgatttctcagacgatcaccagctgggcc caggagtcccacatccaggacccggagctggtccgagtcatgttcagyctgctgaggagg cagtatgatggcatcggcgaactgctgcgggccatgaagaaatcgtacaccatcagcgcc gcctcggtgcaggacgccatcaacctgctggcctctctgggtcaaatcaggtcgctgctt tcagtgcgcatgggcaaggaggaagagaagctcatgattgatgggctcggggacatcatg aacaacaaggttttctaccagcatcccaatctgatgagagttttgggaatgcatgagacg gtcatggaggtcatggtcaacgtcctgggtggagacaagtcccaggagattgcctttccc aagatggtggccagctgctgtcgatttctgtgctatttctgccgcatcagccggcagaac cagaaggccatgtttgaccacctgagctacctgctggagaacagcagcgtaggactggcg tctgaagcgatgcgaggctccactcctctggatgtcgcagcatcttcagtgatggacaac aacggtctggctttggctctggaggaacctgacctagaaaaggtggtgacgtacctggca ggatgcggcctgcagagctgtgcyatactggttgccaagggttacccggacctgggctgg aaccccatagagggagagcgttacctctcattcctgagatttgtcgtcttctgcaatggc gaagccgggcattttggaattataatcagcaaaatatacaatgcagcgggcatgaaggag ctcaaaacgcagttacacaccaagacaactgcaaaaagaagctgtgaaagaggccagaaa gttgatcccaggctccygtttgtgtgctgcaggtctggtgaagaggaaggagaagttatc cacatgggcaacgccatcatgtccttctactccgccctcatcgacctgctgggacgctgc gctccagagatgcatcttatcaatgcaggaaaaggtgaagcgttgcgtatcagagccatc ctgcgctctctggttcccacstcagacctggtgggcatcatcagcatccccctcaagatg cctgtgattaacaaagacggatccgtgacagaacccgacatgtcggcctgcttctgcccg gaccacaaggcccccatggtgcttttcctggacagagtttacggcattgaggaccagagt ttcctgctgcagatgctggaagtcgggttcctgccggacctcaaagcctcggcgtctctg gacacggtgagtccaaaagaaccttcgtctaattcacaactcttaagttctctgattgtc tgcaggcatcttcgaccatccatgatgcagcagctgctcaggcgcctcgtcttcgacgtt cctctgctcactgaatactgcaagatgcctctccggctgctgaccaaccactatgagcag aactggaagtactactgcctgccgtctgggatgggcggcttcggcatggcctctgaggaa gagctgctgctcacaaagaaactcttctggggaatttttgactctctttctcagaagaaa tacgattctgagctgtttaaaatggccaagtcgtgcctgtgtgccatcgctggagctttg cctccagacttcgtggacaccagcttaggggcgatggtggagaagcaggagtcagtggat gcacagggaaactttgagcccaaacccatcaacactgccaacatctcccttcctgaaaaa cttgactacattgctaataagtatgcagagcattcccacgacaagtgggcttcagagaag atgtcggctggctggaaacacggagacagtttggacgagcaggccaaagcccatccgctg ctgaagccgtataaatctttaagtgagaaggagagggagacgtaccgctggcctgtgaaa gagtctctgaagagcatgctggcgatgaactggaacatcgagaggaccaaggagggagaa gccatgttccagcagcgagagagtgaaaaacagaggaagctttcagaaactcagtctaac ggattcagtcctgctccgatggacctgcacaatgtcactttgtcccgagagttacagagt atggtggaagtggttgcagaaaattaccacaacatctgggctaagaagaagaagtcagaa cttctgagtaaaggaggagggttggctcacccgctgcttgtgccctatgataccctgact gctaaagagaagtacagagacaaagaaaaggcccaagagctcttcaagttcctgcagata agtggctatgctatcacaagaggtctgaaggacatggagcaggactcgtcatccatggaa aaacgttttgcctacaagttcctaaagaggttgctgaagaatatcgactctgctcaggag tttatcgcccatcttgaggcgatggccaccagtgggaaaactgacaagtccccccatgac caggagatcaagttctttgcaaaggttttacttccaatgattgatcagacatttaagaac cactgcctttacttcctgtccacacccagcaagaacctgagcagctgcggctgcgcctcc aacaaggagaaggagatggtcaccagcctgttctgtaagatggcagctcttgttagacac aggatttctctctttggaagtgactctgcgatcatggtgagctgtcttcacatcctgtcc cactcactcgacacgagaacagtgatgaaatccggcgcagagctggtcaaagtcggcttc aaggccttctttgagaacgcggcggaggacttggagaagctggtggagatgctgaagctg gggaagttcatgcagtcgcgcgcgcagatgaagagcgtcactcagagcatcaactatgtg accgtggccctgctgcccatcctcactgccctgtttgaacacatcacgacgcacgagttt gacgtggacctgctygtggatgatgtgcagctgtcctgctaccgaatcctgatgtgcttc tacagcctgggaaccggaaagaatgtctttgtggagaggcatctgccagcgattggggag agtctggcgaccttggtgggagcgatgccggtggcgttcctggagcctcatctcaacgcc cacaacccactttcagttttcaacaccaagacgccccgagagcgagccatcctgagyatg cccgacacggtggaggagatgtgtccagagatgcctcgcctcgacaagctgctcaaggac gtcaacgacgtgtcggagtccggcgctcgctacagtgacatgccacaggtcattgaggtc gtcctccccatgctgtgcaactacttatcctactggtgggagaaaggcccggagaactcg ccgccggactccgactgctgcaccatggtgacgtctgaacacctgagcatcattctggga aacatcctgaagatcctcaacaacaacctsggcattgatgacgctccctggatgaaragg attgcagtttactcgcagccaatcatctgcaaagccggagctgatttgttgagaacccac ttcctgcccacaatggagaaactgaagaagaagacggtgaaggttgtgtctgaggaggag ctgctgaaggccgacggtaaaggagacaaccaggaagcagagctgctcatcctggacgag ttcgcggtgctctgcagggacctctacgctttctaccccatgctcatccgytacgtggac aacaacaggtccaggtggctgaaggagccggatgcagactccactgagctcttcaggatg gtggctgagattttcatcctctggtgcaaatccaacaacttcaagcgtgaggagcaaaac tttgtgattcagaacgagatcaacaatctgggcttcctgaccggggagggcaagtccaag atgtccaagtctggtggagaccaggagcggaaacataaacggcgccgcggtgaatattac tccatccagacgtctctgatcgtagctgcgctcaagaagctgctgcccatcggcttgaac atgtgcacaccgggagaccaggagctcatctctttggcaaagattcgctacagcctgaaa gacacggacgacgaggtgaaggagcatttgcgccagaacctccacctgcaggaaaagtct gatgatccagcagttcactggcagctgaacctttataaagacgtagtggtgaaatcggag gagccgtcggattcggagcacacggtggagagaatccagagcatctctgcagccgtcttc aatttggagcaggtggagcagcctctgaggaacaagaartgcrtcgtccagaagctgctg tccaagcagcgcaagcgagccgtcgtcgcttgtttccgcatggctccactctacaactta cccaggcatcgtgctatcaacttcttcatcccggcctatgagagactttggatagaggca gaggagtactcctttgaggaaaagctagttcaggacctggcaaaaaccccgatgaagatc gtggaggaagaggaggaggaggaggctgagatcaagccggatccgctccaccagctcatc ctccacttcagccacaacgctctgacggagagaagctacctggaagttgatcctttatat attgcatatgcagacatgatggcaaagagctgtgcagaggatgaggaggaagaggaagaa gaagggcgggaaaagacattcgaggaaaaggagatggagaagcagaagatcctgtaccag caggcgaggctgcacgcgcgtggggctgcagagatggtgctgcagatgatcagcgccagc aaaggtcgtctgggccccatggtgacctgcaccctcaaactgggcatctccatcctaaat ggaggcaaygtgcaagttcaacagaaaatgctcggctacttgacggacaaaagagaygca ggctttttcaagagtctgtcaggactcatgcagtcttgcagtgtcctggacctgaatgca ttygagaggcaaaacaaggcagaaggacttggcatggtgacgcaagaaggttcaagctcc aaggtgcttcagaacgacgaattcaccaaagatctgttccgctttttgcaacttctctgt gagggacacaacggagatttccagaacttcctgagaacccaaactggaaacacgaccaca gtgaacatcatcatcagcacggtggactacctgctccgcctccaggaatccatcagtgat ttttactggtattattctgggaaagaygtaattgatgaaactgggaagcacaacttctcc aaagctttatctgtcgccaagcagatatttaactcgctcactgagtacattcaggggcct tgcattggaaaccagcagagtttagctcacagcagactgtgggacgcagtcgtcggcttc ctgcatgtgtttgcaaacatgcaaatgaagctttcacaggatgccagtcagattgagttg ttgaaggaactgatggatttacagaaggacatggtygtcatgctgctgtctctccttgag ggaaacgtggtgaacgggacaatcgggaagcagatggtcgacaccctggtggagtcttcc agtaacgtggagatgatcctgaaattcttcgacatgttcctcaaactgaaagacctcacc acgtccgacaactttaaggagtacgacccggaatgcaaagggatcatttccaagaaggag ttccagaagtcgatggagagccagaagcagtacaaccagtcagaaatcgagttcctgctg tcgtgcgcggaggccgacgagaacgacatgttcaactacaaggagtttgtggagcgattc cacgagccggccaaggacatcgggttcaacgtggccgtgctgctgaccaacctgtccgaa cacatgccgcacgacgcccggctcgccaccttcctggacctggccgaaagcgtcctcagc tacttcgagccgtacctggggcgcatcgagatcctgggcagcgccaagcgaatcgaacgc gtttacttcgagatcagcgagtcgagccgcgagcagtgggaaaagccgcaggtgaaggag tccaagcggcagttcatcttcgacgtggtgaacgagggaggagagagcgagaagatggag atgtttgtgaacttctgcgaggacaccatctttgagatgcagctggcctcgcagatctcc gagccggacgccgtggagcagccggaggaggaggaggaggaagaggtgcacagcatcctg gaggagctctccgggggagacgacgccgccctggagtccgcctcggcgttcaccaccgcc tgccgttcggtcaagaagaacctctcagaaatccggcagatcttcaccattaaaacggcg cgcaagcagwtcaagaaaatcaagaagctgagcatcaaggagctgatcaccggcttcttc tccttcttgtggatgatcttcatcggcttctttaagggcattttcagcctcgtgttcggt ttcttccacgtcatytggtcgtccatgttcggcggagggcttgttgaaggagccaagaac ataaaggtgacggacatcctgggcaacatgccggacccgacgcagttcggcatccacggc gacgtgggggaaggagacaaagtggaagccatggagtcgtcgggcagcttggacaaagcc atggctcctgcaggagacgccacagaggtggacgtgatgctggagatgctggcgcctaag aaggagggagggaaacacgtggagcccggcctgggggacgtgtcggagctgagcggggag tcgtccgctgcagacagcaaaaagaaagccgctgccaagacggctgctccctccgagagc gagacggaaaaagcagacactgagacccgggagaaggaggacaaaccaaaggaggaggag gcgaaggaaccagccgtggaggagaaacccaaacccaagtccagtcaacccaaagaggcg tctccggccttcatgtcaaccgtcttcgccattcttgacgtctacctgaataagatactg aactacctggctcgtaacttctacaacctccgtttcctggctctgttcgtttgcttcgcc atcaacttcatcctgctcttttacaaggtcactggtgaagctgaggaagaggaggaaggc gacgaggagaacagttggggtgacgatgacggcgagaacacgctgttcgacatggacgag tttgtgctgcaggagagcaccgggtacatgctgccgacgctgcgcttcctggccatcttc cacaccgtcatctcgctgctctgcctgttcggctactactgcctgaaggttcctctggtg gtgttcaagagggagaaggagatcgccaggaagctggagttcgacggtttgtacatcact gagcagccgtccgacgacgacatcaagggccagtgggatcgactcgtcatcaacacgcca tctttccccaacaactactgggacaagtttatcaagcgcaaggtgatcaacaaatatggc gacatgtatggggccgagcgcatcgctgagcttctgggtctggataagagcgctctggac tttgaccccaccgtggagacggtggagaaggaggcgtccctgctgtcctggctgagctct attgacacaaagtaccacatctggaaactgggagtggttttgactgacaactacttcctg tatctcatctggtacaccaccatgtccatctttggacacttcaacaacttcttcttcgct gcacatctgctggacatcgccatgggcttcaagacgctgcgcaccatcctgtcctccgtc actcacaacggcaagcagcttgtgctgaccgtcggtctgctggccgtggtcgtctacctc tacactgtggtggccttcaacttcttcagaaagttctacaacaagagcgaggacgaagac gagcccgacatgaagtgtgacgacatgatgacgtgctacttgttccacatgtatgtgggc gtgagagccggcggaggaatcggagacgagctggaggacccggccggagatccctacgaa ctctaccgcatcctgttcgacatcaccttcttcttcttcgtcatcgtcatcctgctggcc atcattcagggtttgatcatcgacgcctttggggagctgagagaccagcaggagcaggtc aaggaggacatggaggtaagactcrcgtctcgcctgcaaccgaacgtttcccgtttcctc ttccaggagtcgtacgtgtggaagatgtaccaggagagatgctgggacttcttccctgca ggagactgcttccgtaagcaatacgaggaccagctgggttag

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