Poecilia reticulata (guppy): 103468500 Help Entry 103468500         CDS       T05149                                  Symbol hmcn1 Name (RefSeq) hemicentin-1   KO K17341   hemicentin Organism pret  Poecilia reticulata (guppy) Brite KEGG Orthology (KO) [BR:pret00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:pret04990]     103468500 (hmcn1) Domain-containing proteins not elsewhere classified [BR:pret04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    103468500 (hmcn1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set C2-set_2 TSP_1 EGF_CA Ig_4 G2F VWA_4 C2-set_3 cEGF Ig_C17orf99 V-set_CD47 TSP1_spondin Receptor_2B4 GBD_Hemicentin FXa_inhibition TSP1_CFP_C EGF_3 TSP1_CCN TSP1_ADAMTS VWA7_4 hEGF EGF Coilin_N Fibulin_C VWA_2 Motif Other DBs NCBI-GeneID:  103468500 NCBI-ProteinID:  XP_008413841 LinkDB All DBs Position LG8:complement(3325945..3405471) Genome browser AA seq 5649 aa AA seqDB search MSTLALRVTLAKTSCTKTLSQKDSWTFELMWLLILLSVAFSAAQDSDTLPKNEDIPEGAS TLAFVFDVTGSMYDDLVQVIEGASKILETSLSRPKRPLYNFALVPFHDPEIGPVTITTDP KKFQHELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYKLTHEVLQLI QQKQSQVVFVLTGDCDDRNHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQSSK VNLLSTDHFSQVSNTWQMPFDPSLKEVTVALSGPAPDIEIKTPQGKLLGKADGLTELLHI PNSAKVVNIKDPQPGMWSVKTSSKGRHSVRISGLSTIDFRAGFSRKPTMDFKMTISRPVQ GIPTHILLNTTGLSPPARPDRLELLTITGEVIKTLPIRYYPERQPYNLWNITEFIPPNEA FFLRLTGYDSQGFVFQRVSSVSFSSIVPDAPKVVMPATTNGYYLQKGFIRCQVESLLPFT QRFSRDGKRLGVDQLFSESDXVSWEIEKVTLKDEGHYECIAISSAGTGRARTFLDVSEPP PAITVEGNVTVSPGSHAVLTCQVVSTVAFNLTWLRGGYDARLNPRGNILANLSLQVSNVA PDDSGWYECIAANEGGKTTDRTYLTVQEAPRVSVEPRNQTFMMGDEVRIRCSATGYPPPR LVWTHNDMFITGNNRHRMTPDGTLVIRNTKKKDGGVYGCLASNQAGTDTMTSILTYFEFP VVLAVLREILSNIGEITTMSCSASGIPQPEIWWYKGNIQLHSSDLLEVDXIGGTFTIKQT QLGDAGDYSCVAVNPAGSSSLKIRLDVGAIPKFTLEPSNVVEDIGSNVTLSCQAHGHPEP QVTWRRGDGSSLFNRAHSHSTIIQKKGDLHIFNLWVEDEAEYICEAKNRFGKIQAKASIT VTGLVKPVIAMSPLVISVIEDQQLTLPCVLLAGNPLPERQWLHNYGLVTPDQYVTVRRDG SLHIERVQLDDGGDYTCLAENVIGATNHTTAVYVYVIPTIQYGPQVFSTIEGTPITLPCS ASGVPSPDITWSKGGELLNLGGPAFSLDLDGSLLITSPSGNETGEFVCTATNAAGYATRK VQLTVYVRPKPGVGGTGGLGEPVRMSVIQGEDIVLPCDVQSVPPPTISWAKERQLISPFS PRHRQLPSGSMKILETRVSDSGLYVCVASNIAGNVTLSIELSVLVPPKIQPGPRLIKVQV GHQVELACAVVGFPEPTVSWTKDNRNFPVSHDGTLTLRDVKLDDEGIYTCTATNSAGQDQ AQVKVQVQVPPVVEVPEPPFNSPLQERVLNQRIAFPCLAKGLPKPVIHWLHNGVELTGNE PGVSILDDGTLLILAAVSPLDDGEYVCTAANDAGSTEKKYQLRVNVPPDFRDGDTPGSVS VVLNEPVSLVCDVTGSPKPIITWFKDGSPVVGGNSIQILDMGKSLKLLRAETADAGSYSC KAINIAGSREKEFVLDVLVPPTIVGSGSPMDVSTILKQELTLECKVHGSPFPTIQWYKDR KSVFLGDPNLEVINRGQVLRIKNARLGDQGRYQCSVINTAGKQSKDFNLSVYVPPAIIGG NLTTDVTALLDTMVTLGCEVRGVPHPTITWYRRGQAIMSSRQAQYLERGVRLKIPRVQAS DAGQYTCRVNNVAGNAEKSFELDVYMPPTITGGDDGPTERKVVLSKHLTLECEAAGHPPP SLTWLKDGVPVHHGDSVRLLDQGRKLEILSASISDSGRYICVATSIAGEKEVKYDVKVLV PPFIDGADAVTDSSVIINTPLELECQATGTPAPVITWYKDGKRIRSGEGLRIAASGRRLI ISRAQISDTANFRCLATNEAGDHERNFNVTVQVPPSIRTTGPADRSVILHKPITLECISS GTPPPSLTWLKDGRPVVTTKDHLKLHSAGRTLNITEARLEDSGRYTCLATNAAGEAQQHV RLSVHEPPSILLSADVVNQTVLSGFPTELECKAAGSPLPAVTWYKDGRPLTGAAAVPIRK RGQVLEIEQAHLSDAGMYKCVAVNLAGAAEKVYSLQVFVPPEISSRGGTVTAVVNEAVKL ACEASGVPVPSLTWLKDGSPVASVSHGLQLPSAGRVLSLSSAQVSDTGRYTCVAVNAGGE QQKEYDLRVYVPPNIKGEEVNATVMLGGPVQLHCHSDAVPPPTLLWRKDGRPIFRKPGLI VSADGSLLKVDNAQLQDSGRYTCEATNVAGKTEKNYNLIVWVAPSIRGSEEASPMTVIEG SFITLLCESSGIPPPSLTWMKDGYTLKPDQRLKVLSGGXQLQISSAEKTDTGSYSCTASS AAGSTSKEYSLQVYVRPSIGRSEDNSNDVTVXKGGGVTLHCAAEGVPQPTVTWLKDGRPI EGQHGAQVLNEGRVLQIKDAKVSDTGRYTCIAVNVAGQADIKHDVSVHVPPVITGQVQFP ENVSVVVKNPASLNCEASGIPLPSISWLKDGRPVKATSLVRIVSGGRSLRLLHTAVEDAG KYTCVVANSAGEERKNFDLDILVPPSIVKEGTVMDTKVKESQNITLTCEASGNPPPEIKW LKDGQLLVPDRRQQIVSYGRFLQIFEAHVADTGRYSCVASNSAGERRRHFNLNVLVSPTI AGSGPDISAEEVTVTLSSPTSLVCEVQSYPPALITWLKDGNPFESTRSVRVLPGGRTLQI LNAKKEDAGRYTCVATNEAGETLKHYEVKVYVPPQINKNDIPGEGLAPKEVKIKINSTLT LECVAQAFPSPALQWYKDGQALMADDHVSIIANGRIVQIKHAQVSDTGRYTCVATNLAGE DEKDFDVNIQVPPHFNRPGGVRDTSSISGFGGDPRDVILNNPISLYCETNAVPPPTLTWY KDGKLLTSNDKVLILPGGRVLQIPRAQLEDSGRYTCVAINEAGEDSIQYNVRVLVPPSIR GSDSDVLEEVIVLVNKTAQLDCHVDGNPTPKITWFKDGQAMNSGGKRSILSNGRALQVSN AQVSETGQYVCVXENVAGSAEKHFNLNVHVPPTIVGVSPENVTVVVNNFVSLTCEASGFP PPTLSWLNDRGPIQPKSNTLIMPGGRTLQILKAKVSDGGKYSCVAINAAGQAHKHIYLTV YVPPSIRGNSGDVPVEVNVLVGKSVTLECESNAVPPPIITWYRNGRVVTETTNTHILPGG QMLQIKRSEVSDTGQYVCMASNVAGQVSKNFNLNIHVPPSIDGPAEENVVETISNPVAFT CDATGIPPPSLXWLKNGHIIENSESLEMNIFSGGSKLQIARLQLSDSGTFTCVASNVEGK AHKSYHLTMQVPPSISGSEMPREMGVLVNESIELICEAQGIPTPTIQWLKDGEAIKSTEL KGLRVSPHGNTLTVTQADPAVSGKYTCVASNAAGEEDRIFHLHVYVPPSILGSSEDQTAV LDSSVSIECVATGSPRPQLNWLRNGLPLPVSSNIRLLSAGQVLRINRIQVSDGGSYTCVA SNRAGVDNRQYNLQVHVPPGLEGAGTTEDVTVIRGNLASLLCVADGSPTPTISWLRDGET LTADHRISLLGFNTTLQFXQAQVNDTGHYSCVANNNAGQASRHFNLKVLDPPRIKSSGQP EEVSVVVNNVLELLCEATGIPTPTLTWLKDERPLPQTENLHLLRGGEILRVTAAQLEDTG RYSCLANSPAGDDDKDFLVRVHVPPNISGESTTRHLSVLQKGQVTLECKSDAVPPPTLTW LKDGTPLQKSPRLRILSSGRYLQINMAALSDRAQYTCMASNIAGKTTRLFNLTVNVPPTI KDGSQMVVGHINKPATLECVVSGVPPPRVTWRKNGAVIAENNPRYTFAGDGSLXIPLAQV TDTGRYLCMATNQAGTQRKRIDLQVYGVSSYLIILPVYLNPPVGFVSCRFLVFVSVSVSV VTVELVKSCVASALVFRFSISCYRLLSSGSLVIIAPTVEDTAEYKCVVSNEAGEESRLIX LSVIVPPSIADEPTDIVVTRLSPVVIACTATGVPAPXIDWTKGGMKLLNKGEGYNILPTG HVQIPAAQLSHAGRYTCMAKNIAGSTXRHVQLTVQELPVIQSHPATLDVIYNSAVTLPCR ATGSPRPSITWQKEGINIPATGGVYTILPDGSLQISKASLADSGTFICVAQNPAGTALGK TKLRVQVTPVILSETQELLALLDSSVTLHCEAAGSPPPSITWHKDGQLLTDSGHQRLLSS GSLQIAFVQQSDAGRYTCTAANPAGTDSFDMTLTVQMPPSISGGKQDVVVVEKSQAQLMC VAEGIPQPELSWKKDGNPLSESRGEFTILPSGELIIDSAQPEDAGSYTCVATNSVGEDSR TVTLSVHSHPSFTKLLTDVSLNKGERLVLTCGVSGIPTPTVKWIMNNKNIPVHYNHVNGH SELVIERVSKEDTGTYTCVAENTVGTIKSLGFVYVKEPPIIDGDLHASRIEPLGGNAVLN CEVRGDPLPTIQWSKNGINIQINNRIRQLDNGSLAIYGTVSEDAGSYMCVATNDAGVVER SVTLTLQRAPVITLEPVGTVVDAGTTVVLSCKAEGEPGPMIEWTQHARPLLANDRFSTLS NGSLRITSAQKEDTSEYECVARNLLGSVVVSVALTVRVHGGYSEWTEWGICSVSCGAGTQ KRVRRCNNPLPANGGRHCAGSDAETRSCQGKPCPVDGNWSQWSPWEECSQTCGQGNKTRV RSCSNPPAQHGGRPCVGKAVEAIMCSIRPCPVMGNWGSWLSWSPCSETCGKGVQSRIRLC NNPPPAFDGPQCEGTDTQSQVCKEKPCPVDGKWSSWMSWGPCSVSCGGGSRQRARLCASP APQHGGRTCEGNDVHTDFCNGDRCPINGNWGQWSSWGSCSKTCNGGQMRRYRTCDNPRPS HGGRACAGADSQMQKCSTAECPVDGNWSLWQAWGGCSSSCGGGERTRVRLCNNPPPSNGG RLCPGDPTQLSRCNNQACPGGPHKTRGSIIGNINDIEFGIAYLNATITDSNSGSRTIKAT ISNVPRTLGPAMRKLISILNPIYWTTAQEIGEAVNGYTLTGGVFRRETQVEFATGEILRM THVARGLDSDGALLLDIVVNGHVLQLPSHADINIKDYTEDYIQTGPGQLYALSTRMFIVD KESVPYSWNHTISYDRTKGKMPFLVETLHATAISALYRPLEELLEYSIQASITKGDRSNQ CPHGFTLVSAGPYCADENECDVGNPCSHTCHNTMGTYYCSCPHGLTISADGKTCQDVDEC SLGGNMCHGGQDCENTIGSYRCVMRCGHGFRRTADGLSCTDVDECLESQPCHQQCMNTIG SYRCACEPGFQLRNRRCIDINECRQRVCRLDQQCKNTRGGYTCIDLCPSGMTKSGNGSCV DIDECRDGTHQCRFNQICENTRGSYHCTCPRGFRSQGVGRPCVDINECERLPQPCAHECI NTPGSFKCTCPPGRHLLGDGKSCAGLERLPTYESYSYGYRTSQSSPEQAPNQRLYHSFAS HSYNSFTATNXRYMNRNXREAHKHRSRQGFPACKEGFESRAGHCLDINECEVRDVCQHEC VNTPGSHRCLCPAGYRLMANGKTCQDIDECQEQNIQCGVNRMCFNTRGSYQCIDTPCPPN YQRDPATGFCLKNCPPNDLECTLSPYALEYKLLSLPFGIAANQDLIRLVAYTQDGVMHPR TTFLVVDEDVTLPFALRDENMKGVLFTTRPLREPHTYRMKVRALSYSEDGAIEYQTTFIV YIAVSAYPY NT seq 16950 nt NT seq  +upstreamnt  +downstreamnt atgtcgacactcgccctgagggtcactctggcgaaaaccagctgtacaaaaactttgtca cagaaggattcttggacttttgaacttatgtggctcttaattttattgtcagtggccttt tcagccgcgcaggactcggacaccctgcccaagaatgaggacatcccggagggcgcatcc accctggcgttcgttttcgatgtgaccggctccatgtacgacgacctggtccaggtcatc gagggagcttctaagattttagaaacatccctgagccgaccgaagagaccgctgtataac ttcgctctggtgccctttcatgacccagagattggacctgtaacaatcacaacagaccca aagaagttccagcatgagcttagagagttgtacgttcagggaggtggcgactgcccagag atgagcatcggtgctataaagatcgctttggagatctctttgccaggatcttttatttat gttttcacagatgcccgttctaaagattacaaactgactcatgaagtcctgcagctcatt caacagaaacagtcacaggtggtgtttgtgctgacgggtgattgtgatgataggaatcat attggttacaaggtgtatgaggagattgcctctacaagttctgggcaagttttycaccta gataagaaacaggtcaatgaggttcttaaatgggtagaggaggctgtgcagtcctcaaag gtcaacctgctttccactgatcatttcagtcaggtcagcaacacctggcagatgcccttt gatcccagcctaaaagaagttacggtggctctcagcggcccagcacctgatattgaaata aaaactccccagggaaaactcttggggaaggctgacggcctgactgagcttttgcacatt cccaactcggccaaagttgtcaacatcaaggacccgcagccaggaatgtggtctgtcaag acatcaagtaaagggaggcactcagtccggatctccggtctcagcaccattgacttccgt gccgggttttccagaaaacccacaatggattttaaaatgacaatcagcagaccagttcaa ggtattcccactcacatccttctgaacaccactggactttcccctcctgctcggcctgac cgactggagcttctcacaatcaccggcgaagttatcaaaactttgccaatcaggtattac ccagagcgacagccgtacaacctctggaacatcacagagttcatccctccaaacgaggcc ttcttcctgaggcttacgggatatgacagccagggttttgtgttccagagagtctctagt gtctcgttctccagcattgtacctgatgcacctaaggtggtaatgccagccaccacaaac ggttattacctccagaaagggtttatcagatgccaggtagagagtttgttaccatttact cagcgcttcagcagagatggaaagcgacttggagtagaycaactcttcagtgaatccgat rgcgtgtcatgggaaatcgaaaaggtaactctgaaggacgaaggccactacgaatgcatc gcaattagcagcgctggaacaggacgagctcgtaccttcctggatgtgtcagaaccgcct cctgccatcactgttgaagggaatgttaccgtctcacctggcagtcatgctgttctcacc tgccaagtcgtcagcaccgttgccttcaacctcacctggctgcgagggggatacgatgct cgtctgaacccacgtgggaatatccttgccaacctttcactgcaggtgtccaatgtggcc ccggacgactcgggctggtatgagtgcattgctgctaacgaaggaggaaagaccacagat cggacatatctcacagtacaagaggcacccagggtgtcagtggagcctcgaaatcagacc ttcatgatgggagatgaagtgaggatcaggtgttcagccactggctatcctccaccacgt ctggtttggacccacaacgacatgtttattacgggaaacaacagacaccggatgactcct gatggcactctggttataagaaacacaaagaagaaggatggaggagtgtatggctgtttg gccagtaaccaggctggtactgacacgatgacctccattctcacctattttgaatttcct gtggtgttagcagtcttaagagaaatactcagtaacattggagaaatcacaacgatgtcc tgttcagcgtccggcatccctcagcctgagatctggtggtacaaaggtaatattcagctc cattcctcggatctgttggargtggacawaataggaggaacatttaccataaarcaaacc cagttaggtgatgctggagactactcctgtgtggctgtaaatcctgctggttcctcctca ctaaagatccgtcttgatgttggagctataccgaagttcactcttgagccatcaaatgta gtagaggacattggctccaacgtgacattgtcctgtcaggcgcatgggcatcctgagccg caagtcacatggagaagaggggacggatcctctctgtttaaccgagcccactcacatagc actatcatacagaaaaaaggggacctacacatatttaatctatgggtggaggatgaggcg gagtacatctgtgaggccaaaaaccgctttgggaaratccaagccaaggctagcatcact gtgacaggacttgttaaacctgtgattgcaatgagtccgcttgttatcagtgtgatcgag gaccagcagctcactctgccctgcgtgctgctggctggaaatccactaccagaaaggcag tggctccacaactatggcctggtgaccccagaccagtatgtcacagtgaggagagatggt agcctgcatattgagagagttcagctggatgatggaggcgactacacctgcttggctgaa aacgttataggggccaccaaccatacgactgccgtttacgtctatgttatccctacaatt cagtatgggcctcaagtatttagcacaattgaaggaacacctataactctgccctgcagt gccagtggagtacccagtccggacatcacttggagcaagggtggggagctgctaaacttg ggtggtccagctttctctttggatttggatggcagcctcctcatcacttctccctctgga aacgagactggagagtttgtctgcacagctaccaatgcagcgggatatgcaactaggaag gtgcagctcacagtctatgtccgacccaagcctggagttggtggaactggaggtttagga gagcctgtgaggatgtcagtgatccagggggaggatattgttttgccatgtgacgttcaa agtgtcccaccacccaccatcagctgggcgaaagagagacagctcatctcgcccttttcc ccgaggcatcgtcagcttccatctggatcgatgaagatccttgagactagagtttcagac agtggactttatgtttgtgttgcctcaaatattgctggtaatgtgacgttgtccatcgag ctgagtgttttagttcctcctaaaatccagccaggtccaagattgataaaggttcaggtt ggtcatcaagtagagctggcttgtgcggtggtaggattcccggagccgactgtcagctgg accaaagacaatagaaacttccctgtgtcacatgatggcactctcacactgagggatgta aagcttgatgatgaaggaatctacacatgcacagccaccaactctgcaggccaggaccag gctcaggttaaggttcaagtccaagtcccccctgttgttgaggtgccagagcctcctttc aacagccctctgcaggagagagttttgaaccagcgcatcgcattcccctgccttgcaaaa ggtctacctaagccagtgatccattggttgcataatggggttgaactgacgggcaatgag cccggtgtgtccatcctggatgatggtactctgctgattttagccgctgtctcacctctg gatgatggagagtacgtctgtactgcagctaacgatgcaggatccaccgagaaaaagtac cagctcagagtcaatgtaccaccagattttcgtgatggggacacaccaggcagtgtatca gtagtcctaaatgagccagtcagtttggtgtgtgatgtcacgggaagtccaaaacctatc atcacctggtttaaggatggctctcctgttgttggyggtaacagcatccagattcttgac atgggaaaatctctgaaactgctgagggcagaaacggctgatgcaggcagctacagctgt aaagccattaacattgcaggcagcagagaaaaagagtttgttttagatgtacttgtccca ccaacaattgtaggatctggctctcctatggatgtttcaacaattctcaaacaagagctc acgcttgaatgcaaagtgcacggttcaccttttcccacaatccagtggtacaaagacaga aagtcggtgtttcttggtgatcccaatctggaagtcatcaacaggggtcaggtgttgagg ataaaaaatgctcgacttggagaccagggtcgctaccagtgtagcgtcataaacacagct ggaaaacagtccaaagacttcaaccttagtgtttatgtgcctcctgccatcataggaggc aacttaacaacggatgtgacagcactgctggacacaatggtaacactggggtgtgaagta cgtggagtaccgcatcccaccatcacctggtaccgcagaggacaagccatcatgtccagc cgacaggctcagtatctagagagaggtgtccgactgaagatcccacgagttcaggcgtct gacgctggtcagtacacctgcagggttaacaatgtggccggaaatgcagagaagagcttt gagctggacgtctacatgcctcccaccattactggaggggacgatgggcccacggagaga aaagtggtcctcagtaaacatctgaccctggagtgtgaggcagcaggtcacccaccgccc tccctcacctggctgaaagatggagtccctgtgcatcatggagacagtgttcgtcttcta gatcaggggaggaaattagaaatcctctcagcctccatctcagactctggacgctacatc tgtgttgctacaagcatcgctggagagaaggaggtcaaatatgatgtcaaagtattggtt cctcctttcattgatggagctgacgcagtgacagacagctcagtaataatcaacactcct ctggagctggagtgtcaagccactgggacgcctgcacctgttatcacatggtacaaagat gggaaacgaatcagatctggagaagggttgcggattgcagcaagcgggcgacggctcatc atttctcgtgctcagatctctgacacggctaattttcgctgtctggccacgaatgaggct ggagaccacgagaggaacttcaatgtgacagtccaagtcccaccatctatccgtacgacg gggcctgcagatcgctcagtgattcttcacaaaccgatcactttggagtgcatctccagt ggcactcctccacccagtctcacctggcttaaagatggccgacctgtggtcacaacaaaa gaccacctcaagctgcactcagcaggaagaacactaaatatcacagaagccagactggag gattctgggagatacacctgtctggccacaaatgcagctggagaagcccaacagcatgtt cgactgagtgtccatgagcctcccagcatcctcctttctgcagacgtcgtcaaccagact gttctctcaggcttccccactgagctggagtgcaaagctgcaggaagtccattacctgct gtaacatggtacaaagatggccgacctcttactggtgcagctgctgtcccgatccggaag cgcggccaggtgctggagattgaacaagcccatctatctgatgctggaatgtacaaatgt gtggctgttaacctagcaggagcagcagagaaagtctacagtctgcaagtgtttgtccct ccagaaatctccagtagaggtggaacggttacagctgtggtgaatgaagctgtaaaactt gcgtgtgaggcctctggggttcctgttcccagcctgacatggttaaaagatggaagccct gtggcaagtgtatcacatggtttacagttgccatctgcaggcagagtcctgtctctgagc agtgcccaggtcagtgatactggtagatacacctgtgttgcagttaatgcaggaggggag caacaaaaggagtacgatctgagggtgtatgttccaccgaacatcaagggtgaggaagtg aatgcaacagtgatgctcggtggtccagtacagctgcactgccacagcgacgcagtgcct ccaccaactctcttatggcgaaaagatggccgccctattttcaggaaacctggtctaatt gtctctgcagatggtagtttactcaaggttgataatgctcagctgcaggactcaggaagg tacacttgtgaagccaccaatgttgctggaaaaactgagaaaaactataacttgattgtt tgggttgctcccagtatccgcggctctgaggaggcatctcctatgactgtgatcgaagga agttttatcactctgttgtgtgagtccagtggtataccacctcccagccttacatggatg aaggatggttatactctaaagccagaccagcggctgaaggttttgtctggagggcrccag ctgcagatctccagcgctgagaaaacagacacaggctcttacagctgcacagcctccagt gctgctggctccacctcaaaggagtacagcctccaagtttatgttcgtccttcaatcgga cgtagtgaagacaactctaacgatgtgacagtgayaaaaggaggcggtgtgacgttgcat tgcgctgcagagggcgtcccacagcccacagtcacttggcttaaggacgggcggcccata gagggccagcatggtgctcaggtcctaaacgagggcagagtgttgcagattaaagacgcc aaggtgtcagacacgggacgctacacctgcattgctgttaatgtggcaggacaggcagac attaagcatgacgtcagtgtgcatgtcccacctgttataaccggtcaggtgcagtttcca gaaaacgtcagtgttgtggtgaagaacccagcttctctgaactgtgaggcttctggtatc cctctgccttccatctcctggctgaaggatggaaggccagtcaaggcaactagcttggtg cgcatcgtctccggggggcgtagtctccgtctgttgcacaccgcagtggaggatgctggg aagtacacttgcgttgtcgccaacagcgctggagaagaaaggaaaaacttcgatcttgac attctagttcctccaagtattgtgaaggagggaacggtcatggatactaaagtaaaagaa tcccaaaacatcactctaacctgtgaagcatcaggtaaccctccaccagagattaaatgg ctgaaggacggacagctgttggtgcctgacagacgtcagcagattgtgtcatatggccgt ttcctccagatctttgaggctcatgttgcagacactggaagatacagttgtgtggcatca aacagcgcaggagaacgcagacggcatttcaacctcaatgttctggtttctcccaccatt gctggttcgggtcctgacatttctgcggaggaggttacagtgaccctgagcagccccacc tccctggtctgtgaagtccagtcctaccctcctgctctgatcacctggctcaaagacggc aatccatttgaatcgactcgcagcgttcgagttctcccaggcggrcggacgctgcagatt cttaatgccaagaaggaggatgctggcaggtacacttgtgtggccacaaatgaggcggga gagactctkaagcactatgaggtcaaagtttatgttcctcctcagattaataagaatgat attcctggggaaggacttgcccctaaagaggtaaagatcaaaattaacagcacattgacc ctggaatgtgttgctcaggcctttccttctccagcactgcagtggtataaagatggacag gccctgatggcagatgaccatgtgtccatcatagccaacggtcgcattgttcagatcaaa catgcccaagtgtcagacactggtcgctacacctgcgtcgccactaatctagcaggagag gacgagaaggactttgatgtaaatatacaagtacctccacatttcaataggcctggtgga gtcagggatacttcatcaatctcgggttttggaggggatcctcgtgatgtcatacttaac aatccaatctctctgtactgtgagacaaatgctgtaccccctccaaccctcacctggtac aaagacggaaagctccttacctctaatgacaaagttttgatcctacccggtgggagggtg ttacagattcccagggcgcagcttgaagattctggcagatacacctgtgtggccatcaat gaagcaggagaagactccatccagtataacgtcagagtgctggtacctccaagcataaga ggatcagacagtgatgtgcttgaagaagtcattgtcctggtcaacaaaactgcccaactg gactgtcacgtggatggaaacccaacccccaagatcacctggtttaaagatggtcaggcg atgaattcaggcggaaaacgcagtattctgtctaatggacgagcattacaggtgtcgaat gctcaagtttctgaaacaggacagtatgtgtgtgtggytgaaaatgtagctggaagtgca gagaaacactttaacctgaatgttcatgtgcctcccacgattgttggtgtgagtccagag aatgtgacggtggtggtgaacaactttgtgtccctcacctgtgaagctagcggctttcct cctcccaccctgagctggctaaatgacagggggcccatacagcctaaaagtaataccctc atcatgccaggtggtcgtactttacagatccttaaagctaaagtgtctgatggtggaaag tacagctgtgtggccataaatgcagcaggacaggctcacaaacacatctatctcactgtt tatgtacctccaagtatccggggcaacagcggagacgtgcctgtagaggtcaatgttctt gttgggaaatctgtaaccttggagtgcgagtccaacgccgtccctcctcccattatcacc tggtacaggaatggcagagtggtgacagaaacaaccaacacacatattctgccaggggga caaatgcttcagatcaaacgctctgaggtgtctgatacaggccagtatgtctgcatggcc tcaaatgttgctggccaagtgagcaagaacttcaacttgaatattcatgttcctcccagt atcgacggcccagcagaggagaatgttgtggaaaccatcagcaacccagttgctttcact tgtgatgctactggaatccctccacccagtctcaygtggctgaaaaatggacacattata gagaactctgagtctctggagatgaacatcttctcaggaggcagcaaactacagatagca cggctgcagctttctgacagtgggaccttcacatgtgtggcctctaatgttgagggcaaa gcacacaagagttaccacctcactatgcaagtcccacccagtatctctggatcagaaatg cccagggagatgggagtccttgtgaatgagagcattgagctgatctgtgaagctcaggga atcccgactccaacaatccagtggttgaaagatggagaagccatcaagagcacagaactc aaaggtctcagggtcagtccacatggtaatactctaaccgtgacccaagcggaccctgct gtcagtggaaagtacacttgtgtggcctctaatgctgctggagaagaggacagaatcttt catttacatgtgtatgttcctccatccattctcggcagcagtgaggatcagaccgcagtt ctggacagttctgtcagyatcgaatgcgttgctactgggtcacctcggccgcaactgaac tggctgaggaacgggctgcctctcccagtctcytccaacatacgacttctctctgctgga caagtgctccggataaaccgaatccaagtgtctgatggtggaagctatacatgtgtggca tctaacagagcaggagtggacaacagacagtacaacctacaggttcacgttcctcctggc ctggaaggagcaggaaccacagaagatgtgactgtcatcagaggaaatttggcgtcattg ctctgtgttgctgatgggagtccaactcctaccatttcctggctcagagatggagaaacg ttaacagctgaccacagaatcagtctccttggctttaacaccaccttacagttcarccag gcccaagttaatgacacaggacactacagctgcgtggctaataacaatgctggtcaagca agccgccattttaacctaaaagttctggatcctccgcgtatcaagagctctggtcaacca gaagaggtttctgtagtggtgaataatgtcctggagttgctctgtgaggccaccggtatc ccaacacccactttgacctggctgaaggatgaacgcccactcccacagacagaaaacctg catctcctccgtgggggagagatactccgcgttaccgcagcacagctggaggacacaggc agatacagctgcttagcaaacagtccagcaggagatgatgacaaagatttcctggttcga gtgcatgttccccctaacatttctggagaaagcacaactcggcatctgtcagtgctgcag aagggtcaggtwactctggagtgcaagtctgatgctgttccacctccaactttgacctgg ctcaaggatggcacaccgctccagaaatcgccacggcttcgtattctgtccagtggacgc tatttacaaatcaacatggcggctctttcggacagagctcagtacacctgcatggcgagt aacatcgcgggcaagaccactcgactgtttaacctgactgttaatgtacctccaactatc aaggacggctctcagatggtggtgggacacatcaacaagccagcgactcttgaatgtgtg gttagcggagtgccaccgccgcgagtcacctggaggaaaaatggagcagtaatagcagaa aataaccccagatatacatttgcaggggatggatctttayacatccccttagcccaggtg acagacaccgggcgctacctgtgcatggcaacaaatcaagctggtacacagcgcaagaga atcgatcttcaagtttatggtgtgtctagttacctgattatcctccctgtgtatttaaac ccacctgttggctttgtctcttgtcggttcctcgtctttgtcagcgtcagtgtgtcagtc gtcacagtagaactggttaagtcttgtgtggcatcagctctcgttttccggttctctatc agttgctaccgattgctgtcatcaggctccttggtgattatagctcckacagtggaggac actgcagagtacaaatgtgtggtttctaatgaagctggagaggaatccagattaattamt ctttcagttattgttcctccatccatagcagatgaacccacagatatagttgtgacaaga ctgtccccggtggttattgcttgtactgcaactggggtgcctgcacctktaatcgactgg accaaaggcggcatgaagcttctcaataaaggggaaggatacaacattttgccaacaggt catgtccagatccctgctgctcagctcagtcacgctggacgctacacctgcatggccaaa aacatcgctggctccacacasagacatgtgcagctaacagtgcaggaactgccggtgatc cagtcccatcccgccacactggatgtgatctacaacagcgccgttactttgccctgcaga gccacaggctcacccagaccctccattacctggcagaaggagggcatcaacatacccgcc actggtggagtttacacaatacttcctgatggaagtctccagatctccaaggcgtctctc gcagactctgggaccttcatttgtgtagcacaaaaccctgcaggcactgcactgggcaag accaaactcagagtgcaagttactccagtgatcctttcagagactcaggagttacttgca cttttggactcctctgtgactcttcattgcgaagctgcaggatcgcctccaccctccatc acatggcacaaagacgggcagctgctgactgactccggacaccagcggctgctcagctca ggatccctccagatcgccttcgttcagcagagcgatgctggaagatacacttgcactgct gccaatcctgccggcactgacagctttgatatgacacttactgtacagatgcctccttct atcagtggtggaaaacaggatgtggttgttgtggaaaaaagtcaggctcagctgatgtgt gtggcggagggcatcccacaacccgaactgtcctggaaaaaagacgggaatcctctcagc gaaagccgaggggagttcaccatcctgccatccggggagctgattattgacagcgcgcag cctgaagatgccggcagttatacttgtgtcgcaacgaattcagtcggggaggacagcagg acggtgacgctgtcggttcattctcacccctccttcaccaaactgctcacagatgtttct ctcaacaaaggagagcgactcgtgctgacctgtggtgtcagtggaatcccaacacccacc gttaaatggatcatgaacaacaaaaatatcccagtccactataatcatgtgaatggtcac agtgagcttgtgatagagagagtaagtaaagaagacactggtacctacacatgtgtagct gaaaacacagtggggaccatcaagtccctgggattcgtctatgttaaagaacctccaata atcgatggggacctgcatgccagccgaattgaacctcttggtggtaatgccgtcctgaac tgtgaggttcgaggcgacccgctgccaactatccagtggagcaaaaatggcataaacatc cagatcaacaaccgaatccgacagctggataacggctccctggccatctatggcacagtg agtgaagacgcgggcagctacatgtgtgtagcaacaaatgatgctggggttgtggaaaga agcgtcacccttacacttcagagagctccagttataactttggagccagtcggaacggtt gtggatgcaggtaccactgtggttcttagctgtaaagcagagggtgaaccaggacccatg atagagtggacccaacatgcacgccccctgctggcaaatgaccgtttctccaccctgtct aatggctccctccggatcaccagtgcccaaaaggaggacacgtctgaatacgaatgcgtg gccaggaacttactcggatcagtggtggtcagcgtcgctctcactgtccgcgttcatggt ggatattctgagtggactgagtggggcatctgcagtgtgtcctgtggcgccggtacccag aaaagagtcaggcggtgtaacaatccgttaccggctaacggaggccgccactgtgcagga tcagacgcagaaacacgcagctgtcaggggaaaccatgtccagttgatggcaactggtca cagtggtctccctgggaggaatgttcacaaacctgtggtcagggcaacaaaacgagggtc cggagctgcagtaacccacctgctcagcacgggggcagaccatgtgtggggaaggcagta gaagctataatgtgcagtatcagaccatgtccagtgatgggcaactggggttcttggctg tcatggagtccctgcagtgagacctgcggtaagggcgtacagtccaggatccgactgtgc aacaaccctcctccagcattcgacggcccgcagtgtgaaggcacagacacccaatcacaa gtctgcaaggagaaaccctgtcctgtggatggaaagtggtcgtcatggatgagctggggg ccctgcagtgtttcttgtggcggtgggagcagacagcgggcacgcctctgtgcaagcccc gcccctcagcatggtggcagaacatgcgagggaaatgacgtgcacactgatttctgcaat ggcgaccgctgtccratcaatggtaactggggacagtggagtagctggggcagctgcagc aagacatgcaacggaggtcagatgaggcgctacaggacctgtgacaaccctcgaccttct catggtgggagagcttgtgcaggagccgattcacagatgcagaaatgtagcactgcagaa tgtcctgtggatggtaactggagcttatggcaggcctggggaggatgctcctcttcctgc ggcggaggagaaaggacacgtgtccgactttgtaataacccgcctcccagtaacggtggc cggctttgcccaggtgaccccactcagctatcaagrtgcaacaatcaggcatgcccaggt gggcctcataaaactcgaggaagcatcataggaaacattaatgacattgagtttggcatc gcctacctaaatgccacaatcactgacagcaactcgggcagcagaaccatcaaagccact atttcaaatgtaccaagaactttaggtcctgcgatgaggaagctcatctccatcctgaac cccatctactggaccactgcacaggaaataggagaggcagttaacggttacaccttgaca ggcggtgtcttcaggcgagagacgcaggtggagtttgctacaggtgaaatcctgaggatg acccacgttgctcgaggcctggactctgatggagctttgcttctggacattgtagttaac ggccatgttctgcagctgccttcacatgctgacataaacatcaaggactacacagaggat tacattcagaccggtcccggtcagctgtatgctctgtccacccgcatgttcatcgtcgac aaggaaagtgtgccctactcctggaaccacaccatctcctatgatcgcactaaaggaaag atgcccttcctggtagaaacgctccatgccacggccatcagcgctctctaccgccccctg gaggaattgttggaatacagcatccaagccagtataaccaaaggtgatcgcagcaaccag tgtcctcatggcttcactctggtgtctgctgggccttactgtgcagatgaaaatgagtgt gacgttgggaacccctgttctcatacctgccacaacaccatgggaacctactactgctct tgtccgcatggcctcaccatatcagctgatggcaaaacctgccaagacgttgacgagtgc tcccttggtggaaacatgtgccatggcggacaagactgtgaaaacaccattggctcctat agatgtgtaatgcgctgcggccacggcttcaggagaacggctgacgggctcagctgcacc gatgtggacgagtgcttggagtcccagccgtgtcatcagcagtgtatgaataccatagga agttatcgttgtgcctgcgaaccgggctttcagctcaggaacagacggtgcatcgacata aacgagtgcaggcagagggtttgccgtttggatcaacagtgtaaaaacacgcgaggcggt tacacctgcatcgatctgtgtccgagtggaatgaccaaaagtgggaacggctcatgtgtg gacatcgacgagtgcagagatggaacgcatcagtgcagattcaaccagatctgtgagaac accagaggcagctaccactgtacgtgtccacgtggtttcagatctcagggagtaggacgc ccatgtgtcgacataaatgagtgtgagcggctccctcagccctgtgcccatgagtgcatc aacactcctggtagtttcaagtgcacctgcccaccaggacgccacctgctgggagatggc aagtcctgcgctgggctggagcgtctacccacctacgaaagttactcgtacggctaccgc acgtcccagtcctctcccgaacaagcgcccaaccagcggctgtaccacagctttgcttct cacagctacaactccttcaccgccacaaatargcgctacatgaaccgtaaccrgagagag gctcacaaacaccgctcaaggcagggtttccctgcttgtaaggaaggttttgagtccagg gctggccactgcttggatatcaatgagtgtgaagtgagggatgtctgccagcatgagtgt gtgaacacaccagggagccaccggtgcctctgtcctgctggttaccgtctgatggctaat ggaaaaacatgtcaagatatagacgagtgccaggagcagaacatccaatgtggagtaaat cggatgtgcttcaacacaagaggaagctaccagtgcatcgacacaccctgtcctccgaac taccagagggacccagccacagggttctgtttgaagaactgcccaccaaacgacctggag tgcacaytgagtccatatgcgctggagtacaagctgctgtctctaccttttggtattgca gccaaccaggatctcatcaggttggtggcctayacacaggacggcgtgatgcaccccaga accaccttcttggtggtggacgaggacgtcaccttgcccttcgccctccgagacgagaac atgaagggcgtgttgttcaccacacggccgctgcgagagccgcacacgtaccgcatgaag gtgcgagcgctctcttacagcgaggacggcgccattgagtaccagacaaccttcattgta tacatcgctgtctctgcctacccttactga

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