Poecilia reticulata (guppy): 103476732 Help Entry 103476732         CDS       T05149                                  Name (RefSeq) ankyrin-3 isoform X1   KO K09259   ankyrin-3 Organism pret  Poecilia reticulata (guppy) Pathway pret04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pret00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     103476732  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:pret04812]     103476732 Cytoskeleton proteins [BR:pret04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     103476732 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ank Ank_2 Ank_4 Ank_3 Ank_5 UPA_2 ZU5 ANK_LRRK2 Death Ank_KRIT1 Motif Other DBs NCBI-GeneID:  103476732 NCBI-ProteinID:  XP_017164395 LinkDB All DBs Position LG15:complement(11916931..12009996) Genome browser AA seq 4694 aa AA seqDB search MAHAASQLKKNRGEVDVNAIEDEKEKRRKSRRASSREQKRKSDSNASYLRAARAGNLEKV LDYLKSGVEINICNQNGLNALHLASKEGHVEVVAELLKLGATVDAATKKGNTALHIASLA GQAEVVKELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLENNASQSIATEDGFTPL AVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKMMVN RTTESGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNSNMVKLLLD RGSKIDAKTKDGLTPLHCGARSGHEQVVEILLDRGAPILSKTKNGLSPLHMATQGDHLNC VQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKLIVDKKANPNAKALNGFTPLHIACK KNRVKVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVHALTRHGASPNITNVRGETA LHMAARAGQADVVRYLLKNGAKVDTKSKDDQTALHISSRLGKVDIVQQLLHCGASANSAT TSGYTPLHLAAREGHQDVASMLLENGASLSSSTKKGFTPLHVAAKYGKMEVASLLLQKRA PPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGSSPHAAAKNGYTPLHIAAKKNQMDIGTT LLEYGADTNAVTRQGISPIHLAAQEGSVDLVSLLLAKNANVNVCNKSGLTPLHLAAQEDK VNVAEILVINEADVTSQTKIGYTPLHVACHYGNAKMANFLLQNHAKVNAKTKNGYTPLHQ AAQQGHTHIINLLLQHGASANDLTANGNTALSVARRLGYISVVDTLRPMTDENLSAMSAS EKHKINVPETINEFLDMSDDEVRTNVPQILREESFSDVDEGEDAMTGDTDKYLRPQDLKE LGDDSLPQEGYMGFSIGARSASPRISLHSFSSDRSNTLNRSSFARDSMMIEEILAPTKDT LQSVCKDISYLVDPLNKHLAVTRDHSSDCVRRYSWTPDTMDHSHNTVSSPIHSGVSSPLA QYDSRFLVSFMVDARGGSMRGSRHNGLRIIIPPRKCTAPTRITCRLAKRHKLAYPPPMVE GEGLVSRLVEVGPAGAQFLGPVIVEIPHFGSMRGKERELIVLRSDNGDTWKEHQFDTRPE DLTELLAGMDEEMDSPDELEKKRICRIITRDFPQYFAVVSRIKQESNHMGPDGGVLSCST VNMVQASFPQGALTKRIRVGLQAQPVPDELVRAVLGNRATFSPIVTVEPRRRKFHKPITM TIPVPPRSAEGHPSGQRGESAPCLRLLCSITGGTSPAQWEDITGTTPLSFVTDCVSFTTN VSARFWLADCHQIPETVSLASQLYRELICVPYLAKFVVFAKMNDTVEARLRCFCMTDDKV DKTLEQQENFEEVARSKDIEVLEGKPIFVDCYGNLSPLTKSGQQLVFNFYSFKENRLPFN VKVRDVGQEPCGRLSFLREPKTTKGLPQTAICNLNITLPTHKKDMESDPDDETEKPERRH TFASLALRKRYSYLTDPAAKTTDRSPPRTQPSGYPHKPVFSTRSYQAWSPVPVTGPIQAK SGFGSLSSSSSNTPSASPLKSVWSINSASPIKTNIPGSPASSVKSVSDTASPIRSYRSIS SPIKTVIHQSQYPVQVTPSPLASPGKSASDPLSMKGLAALTSRTPIASTGGGSPYLERTS MGLTPPTSPKSSLSMFSSPLPYKTILGSSTGTTPSSSPIKTVPGLTSMRSLAMDSTAPVR NLFSSLSSPLKSSNSPSAAVLINGTVSPAQYRSSSPTSHLASSLQERIQATTNAATTSVN AAFDEVEKTFNSCSAGYGTLKSLSSSASSSYQSIRSSASGSLYPSLRSPPNVTTAVTSST MTVPVYSVTNVVPESQLKKRSEVPPSVAVLLSPRKSIPSDMNVQSSFVRTLSPVKVPLYS PGIKSNAASPLSSSQEILKDVAEMKEDLIRMSAILQTESNSTASKGFQSDSPKEVKIEDE EPYRIVEKVKQDLVKVSEILTKDSRKDGRISPARGSLDDIHFSKVQVEQPPSNWSYPPRY ETVVSQARSKPISDRDFNLSKVVDYLANDNSSFSKMHDTKQKADEGKREAEGKEKQKRVL KPTTAVQEHKLKMPPTTMRSSPSEKELSKVTDALFSGDTVLESPDDIFHEQDKSPLSDSG FETRSERTPSAPQSAEGTGPKTPFQDIPVPPVITETRTEVVHVIRSYEPEDDKQLAMEDV DSVRNIDSDFKKHQTPSLSTPDQNKCHSVKCSPDEDPMGKGMRLKEETHITTTTRMVYHK PPGKETSSERCEETMSVHDIMKAFQSGKDPSRELAGLFEHKSGNEEVSQRFLEDINSKPK VERIIEVHIEKGSKAEPTEVIIRETKNHAEKDMYYYPGSRQDDEEPEESLPVYLESPRVN TPLSQEEDSRPSSAQLVADDSYKTLKLLSQQSVEFHEDESSELRGESYNFAEKMLLSEKF DQSHSDTEEYLRDRSRYHSPDRSTPSKARSPGPRTEYVFRSSRNVFDKSGRMANVDDNFD KLTLLQYSSEPGSPKQSVWMRVPDETQIKERDQSEYEDRVDRTVKEAEEKLSEVSQFFRD KTEQLNDELSSPEKKSRRPDFRESRSGPSSTQSSPERSPYRSGGSGEEWNRERLRDRFGP SDRKCSSLPSSPERRVLLQLSDNDPRKQGDGKLQGSPGDSPKSFQMSSSKVSAVRLKFEQ EAQRQDRGSSGSQNQNPPIRKLQETRLPVYQMFSGSRSQKAPDSPANQRKCKETESNKSS PKHETSGKDQEENKSLKTWERQGYGQCKPQSPKLSNYSAHDSTKDCSSDSQRQETTKKII YTEFVVRESPSTNDGLKKNSESQIPVRKSSNFSENPKSTSLKLEEPSERPGPHTPTLGRN RLHSSSESNRSTRGSSLGKSTVSSESSQSNVVCNGVDDDDDQVQYLDQATPVVVTEGFKD IKPLPVYVSIQVGKQYEKETSSGQLGTYKKIVSQESRTVHETRGAVYSVKQKQSPSPQGS PEDDTLEQVTFMDSSGKSPVTPEAPSSEELSLTSRTPDSVIGFMTSMPSTIPEESEEEDG KTFIYKEPLKAKPKPASPENHSKKQEGERGKSKEKRVAYIEFPPPPPLEAEQCSAEKRSG CTSSETETEMIEVNLQEEHDRHLLAEPIIRVQPPSPIPPGADNSDSSDDESVFHPVPVKK YTFKMKEESEKRQKPKKSEKNGAKESGVNGGKGEDAELEQNGNDQSITDCSIATTAEFSH DTDATEIDSLDGYDLQDEDDGLSEDPKTSSLSNDGKAIDRSFNQSKLEVIEEEKCEEGSD NGKTKSGTSGAKASGEKKDYTLEGRHPDRKGFGENYFGYQIQDELNSTFKTVATKGLDFD PWSTKGVDNEGLFESKAKEEDPKPYSLSAEEKSQATTPDTTPARTPTDESTPTSEPNPFP FHEGKMFEMTRSGAIDMSKRDFVEERLQFFQIGEHSSDPITGEKGRGGKILGVPSSQSKT GERSTVDGKMTVVDTTLDSSSTRPTTPATTAAKYNPAQPGSDIGCAITDIPACEAIAETA SSCTITASKVDSKLRTPIKMGIAASITVKKDSGDLTNCKAELSEGQVVPEYISIEGQSSE KQSSSHSELRKEKKDYPSENCNNNNNLESSSVQANYIQCGSLVFNLQSSSEPTLQKASRI ETLCCKDKNERVEVPSGSQAQEQKTETVKESEAKQPRSRLPVKASGWSFHTQGTAIGKQK PKQAVAGEVRKRGEPVIAKVEPRSRIPVKDVKKSSPAATASLPVSVRITSHPVKTLNTGR AVIQLPTRQPQKDRHQFSSVTSEGASRQNRQDNPSELCKRTIEYFKDISGETLKLVDRLS DEEKKTQTEQSEEDSTSRSTSLSDASQPSQPSQPSRSSRSGRGSRAEAGAASVRAKVATT DRGSGSERSRRSRRTGGKEGSQGLTGSRTPPIAEIKPSPQSPCERTDLRMAIVADHLGLS WTELAREMNFTVDEINHIRLENPNSLTAQSFMLLKKWVSREGKNATTDALSEVLTKVNRM DIVTLLEGPIFDYGNISGTRCFADDNAVFRDQADDYQSILAELQSPATLQPSPHFLEPEL PATPNPSLAQHQHLHYPEPDNSCNHPQFADWSPVVDPCSKEPDSPPKSPPRPCELALPAP TFDLPDPIPPKVRKPHIALNDQLLLSEEEDRPFQEMEPTLKPRSQSFPTMCELDIDMAFS TSSPSLSSMSSITPSSPDRSCIGTRLGNASDGAQEDIGQTGGQVEVKEEIEKVVEIVSTQ LVERNGLVEKLVTQELIKNVERKCEMVAKDRSQLVEEGIILLEPKRSAEQDKDNVNEQHD EVRDGSRTAAREEEKAEDELNVLMQHVSLPDKVVKEAVGQSLDVGERVQVKEKVEDPESE LQSKDGQDICDTLEGATERQTLSDLSPQAWVKVLEQLQPYESGSNEKEEKQRGREIPEEA LGSLLEEVNKEGSEEKEKEEEEEDDEKVTQSRNQERLEEVEHAEKNICSLSGWHSDSSSV NVEPPTPGRSVSSDLLDKQESQENSSESITSSSRAESGRSRPNGDNSKHSPQDASSDSSN GRKDGTPVSEKKVQVSVDSGSEEEQTVTTRIYRRRLIIKGEEAKNIPGESVTEEHYMDHD GNLISRKVIRKVIRRVSAPTPENQGGDRWHSDLHHSPTQQDYGRGMERGNADDQGTKSTS RRDGLGLAGLQELR NT seq 14085 nt NT seq  +upstreamnt  +downstreamnt atggctcacgcggcctcccagctgaagaagaatcggggggaagtggatgtgaatgcaata gaggacgagaaggagaagcggaggaagagcaggagagcgtcgtcccgggaacaaaagaga aagtctgacagtaatgctagttacctgcgagctgcccgggcggggaaccttgaaaaagtc cttgactacctcaagtctggagttgagattaatatttgcaatcagaatggcctaaacgct cttcatctggcctccaaagagggacatgtagaggttgttgccgagctgctgaagcttgga gccactgtggatgcagccacaaagaaaggaaacactgctctgcacatagcctcgctggct ggccaggcggaagtcgtcaaagagctggttaccaatggagccaacgtcaacgcacaatct cagaatggcttcacccctctctacatggcggcgcaggagaaccacctggaagtggtgcgg ttccttctggagaacaatgccagccagagcatcgccaccgaggacggcttcacccctctg gcggtggccctccagcagggccatgaccaggtggtctccttgctgctggagaacgataca aagggcaaggtgcgtctgcctgccctgcacatcgccgcacgcaaggacgacaccaaggcc gcggccctgctcctgcagaacgaccacaacgccgatgtggagtccaagatgatggtgaat agaacaacagagagcggcttcactcccctgcacatcgcagctcattatggcaacattaac gtggccacgttgctgcttaaccgaggggctgctgtggacttcatggctcgaaatgacatt actccgcttcacgtggcatcgaaaaggggcaacagcaacatggtgaagttactactagac agagggtccaaaatagatgcaaagaccaaggatggtctgacgcctcttcactgtggagcg aggagtggccacgaacaggtggtagaaatccttttggaccgaggagcgcccatcctgtcc aagaccaagaacggcctgtcgcccctgcacatggccactcagggggaccacctgaattgc gtccagctcctgctgcagcacgatgtgccggtggatgatgtcaccaacgactacctgacg gcgttgcatgtcgccgcacactgcgggcactacaaggtggccaagctcatcgtggacaag aaggccaatcccaatgcaaaagctctgaacggcttcactccgcttcacatcgcttgcaag aagaacagagtaaaagtgatggagcttttgctgaagcacggggcgtccatacaggccgta acagagtccggcctaacgccgatccacgtggcagccttcatgggccacgagaacatcgtc cacgcactaacacgccacggagcgtcgcccaacatcaccaacgttcgaggggaaacggct ctccacatggcggcgagggccggccaggcagatgtagttcgttacctgctgaagaacgga gccaaggtggacaccaagtccaaggacgaccagacagcgttgcacatctccagtcggctg ggaaaggttgacatcgtccagcagctgctgcattgtggtgcctctgccaactctgccacc acttcaggttacacgccccttcacctggccgcccgcgaagggcaccaggatgtcgcctcc atgctgctggagaacggtgcctcgctttcctcctccacaaagaaagggttcacgccgctg catgtagcagcaaagtacggcaagatggaggtggccagtttgcttcttcagaagagagcc ccgcctgatgctgcaggaaaaagtgggctaactccgctgcatgtagccgctcactacgat aatcagagagtggcgctgttactgctggatcagggatcttcccctcatgctgccgccaag aatggctacacgcctctccacatcgctgccaaaaagaaccaaatggacatcgggaccaca ctgctggagtacggcgcagacaccaacgcggtgacgcggcagggcatcagtccaattcac ctggcggcgcaggagggcagcgtggaccttgtgtccctgctgctggccaagaatgctaac gtcaatgtgtgcaataagagtggactcacgcccctgcacctagcagctcaggaagacaag gtcaacgttgcagaaatccttgtaatcaacgaggctgatgtcacctcacaaacaaagatt ggatacactcccctgcatgtggcctgtcactacggcaacgcaaagatggcaaactttctt ctgcagaaccacgccaaagtcaatgccaaaacaaagaacggctacactccactccaccaa gcagctcagcagggccacacccacatcatcaacctgctgcttcagcacggagcctcggcc aacgacctcaccgcgaatggaaacactgccctttcagtggcccgccgtctggggtacatc tccgtagtggacactctgagacccatgactgatgaaaacctctcggctatgagtgcctcg gaaaaacacaaaatcaatgtcccggagaccataaatgagttccttgacatgtcagatgac gaagttcggactaatgtgccacagattctcagagaagagtctttttctgatgttgatgaa ggtgaggatgcgatgaccggtgacactgacaaatacctgcgacctcaggacctcaaggag ctgggggatgattctctcccgcaggagggctacatgggcttcagcataggagcgcgctct gccagccctagaatcagcctccactcattcagttcggataggtccaacacgctcaaccgg agctcctttgccagagacagtatgatgattgaggagatcctggcccccacaaaagacacg cttcagagtgtctgtaaagacatttcctacctggtcgacccacttaataagcacctcgcc gtgaccagggaccacagttcggactgcgtgcgacgctacagctggactccggacaccatg gaccacagtcacaacaccgtgtccagccccattcactccggcgtctcgtccccactcgct cagtacgactccaggttcttggtcagcttcatggtggacgcccgtggcggttcaatgaga ggaagtcgccacaatgggctgcgcatcatcattccccccaggaagtgtacagcgcctaca cgcatcacctgccgcttggctaaaaggcacaaactggcctaccctccacccatggtggag ggggagggcctggtcagtcggctggtggaggttggccctgctggtgctcagttccttggt ccagttattgtggagattcctcattttggttcaatgagagggaaagaaagggagctaatt gtgttgaggagcgacaacggcgacacttggaaggagcaccagtttgacaccaggccagaa gatctcactgaactgctagctgggatggatgaagagatggacagtccggacgagttggag aagaagcgcatctgccgcatcatcactagggatttcccccagtattttgctgtggtgtcc aggatcaagcaggagtccaatcacatgggtccagatggaggagtgctgtcctgcagcacg gtgaacatggtccaggcctcgttcccacagggggctctaaccaagaggatccgcgtgggc ttgcaggctcagccggtgccagatgagttagtcagggcggttctgggaaacagagccact ttcagccccattgtcaccgtggagcccagaaggagaaagtttcacaagcccatcaccatg acgatccccgtccctcccagatcggcagaaggccatcccagcggccagcggggcgaatct gcgccgtgcctgcgtttgctctgcagcatcacaggagggacgtctcctgcacagtgggag gacatcacaggaaccacgccgctgtcctttgtaacggactgtgtttccttcaccacaaat gtatcggccaggttctggctcgcagactgtcaccagattcctgagacggtaagcctagcg tctcagttataccgggagctgatctgcgtgccgtacctggccaagtttgtggtgttcgca aagatgaatgacactgtggaggcccggctgcgctgcttctgcatgactgatgacaaggtg gacaagactctagagcaacaagagaacttcgaagaagtggcacgcagcaaagatatcgag gttctggagggaaagcccatctttgtggattgttacggcaacctttcacctctcaccaaa agtgggcagcagctggtttttaacttctactctttcaaggaaaacagacttcctttcaac gtcaaggttcgagatgtaggccaggagccgtgcggccgcctctccttcctgagagagccc aaaaccaccaaaggccttccacagactgccatatgcaatttgaatatcacactgccaacc cacaagaaggatatggaatctgaccctgatgatgagactgaaaagccagaacgacgtcat acctttgcatccttagctttgcgtaagcgctacagctatttgactgacccagctgcgaaa acaactgatcgaagcccgccgagaacacagccttctggctaccctcacaaacctgtcttt tcaacaagatcttatcaggcgtggtcgcctgttcctgtcaccggccctatccaagccaag tctgggtttggctccctctccagctcgtcatcaaacacgccttctgcctctcccttaaag tctgtctggtccatcaactctgcctctcccattaagaccaacatccctggatcacctgcc tcctctgtcaagtcagttagtgacacggcctctcccatccgatcctacagatccatttcg tctccgataaaaactgtaatccaccaatcccagtaccctgtccaggttacccccagcccc ctggcttcacctggtaaaagtgcttcagaccctttgtccatgaaaggattagcagcattg acttctaggacccctatagcgtcgactggaggaggaagcccttatcttgagagaacgtca atgggcctgaccccaccaacctctcccaaatcttctctcagcatgttcagttctcccctt ccatataaaactattttgggaagttcaactggtacaactccatcctcctcacctataaaa acagtccctggtcttacatctatgcgctcccttgctatggattccactgctcctgtaaga aacttattctcctccctttcatcgcctcttaaatccagcaactctccgagtgctgccgtt ctgattaacggaactgtgtcacctgcacagtaccgctcttcatcaccaacatctcatctc gccagcagcctgcaagaaagaatacaagcaaccaccaatgccgctacaaccagtgttaat gcggcttttgatgaagttgaaaagacattcaattcttgctctgcaggctacggcaccctc aagtctttgtcttcatctgcctcctcctcgtaccagtccattaggtcatcggcttctggt tccctctatccctccctaagatcccctcccaatgtcaccactgctgtaacttcaagtaca atgactgttccagtgtactctgtgactaatgtggtcccagagtcccagttgaaaaagaga tctgaggtgcccccctcagttgctgtccttctgtcaccgagaaaaagtattccgtctgac atgaatgttcagtcctcctttgtcagaactctgtcccctgtcaaagtacccctgtattcg cctggcatcaaatccaatgcagcctcaccattatcatcaagccaagaaattctgaaggac gtcgctgaaatgaaagaggacttgattagaatgtcagccattttacagacagaatcaaac tctacagccagcaaagggtttcagtccgattctcctaaagaggttaagatagaggacgag gagccatatcggattgtggagaaagtaaagcaggacttggtaaaagtaagtgaaatcctg actaaagattccagaaaggacggtagaatttctcctgccagaggttcattggatgacata catttctcaaaagtccaagttgaacagccaccaagcaactggagttacccaccaagatat gagacagtagtttctcaagcaagatcaaaacccatatctgacagagatttcaatctatcc aaagtggttgactacctagccaatgataatagctctttttccaaaatgcatgacacaaaa cagaaagccgatgaaggaaaaagagaagcagagggtaaggagaagcagaaacgagtcctc aaaccaactacagcagttcaggagcataagctcaaaatgcctcctacaaccatgcgatct tccccatcagaaaaagaattaagtaaagtgactgatgcactttttagtggagacactgtg ctggaatcccctgatgatatatttcacgagcaggataaaagtcctctctcagacagtggg tttgaaaccaggagtgagaggacgccatcagctcctcaaagtgcagaaggcacaggtccc aagactccttttcaggatatcccagttccaccagtaatcacagagactagaactgaagtt gtgcatgtcatcagaagctacgagccagaggatgacaaacagcttgcaatggaagatgta gattctgttagaaacattgattcagatttcaaaaagcaccagactccctctctgtcaact ccagatcagaataaatgccattcagtaaaatgtagccctgatgaagacccaatggggaag ggaatgaggctaaaagaggaaactcacatcacgaccaccactaggatggtgtaccacaaa ccacctggcaaagaaacatcgtccgagagatgtgaggaaactatgtcggtgcatgatatc atgaaggcttttcagtcaggaaaggacccctccagagagctagctggactgtttgaacac aagtctggcaatgaggaggtttcacaaagatttcttgaggacatcaactccaaacccaag gttgaaagaataattgaggttcacatagagaagggtagcaaagcagaaccaacagaagta ataatcagagaaacaaaaaaccatgcagagaaggacatgtattattacccagggagtaga caagatgacgaggaacctgaggagtcacttccagtgtaccttgagtcccctagagtgaac acacctctgtcacaggaggaagacagtcgtcctagttctgctcagctagtggcagatgac tcctataaaacattaaagttacttagccagcaatctgtagagtttcatgaagacgaatca tcagagcttagaggagaatcatacaactttgcggaaaaaatgctattgtctgagaaattt gatcaatctcattcagacactgaggagtatctcagagatagatctcgataccactcacct gacagaagcacccccagtaaggcgaggtcacctgggccaaggacagagtatgtatttagg tcatcaagaaatgtctttgacaaatcaggacgaatggctaatgttgatgataactttgac aaactgacacttttgcagtattcctcagagcctggtagcccaaaacagtctgtttggatg cgtgtgccagatgaaacgcagattaaggagagagatcagtctgaatacgaggacagagta gataggactgttaaagaagcagaggagaagcttagcgaagtatctcagttttttcgggat aaaacagagcagcttaatgatgagctgtcatctccagagaagaaatctcgcagaccagat tttagggaatcccgatctgggcccagttcaacccaaagtagcccagagaggtcaccgtat aggagtgggggtagtggggaggagtggaacagagaaaggttaagagacagatttggccct agtgatagaaaatgttccagtctacccagtagtcctgaaagaagagtattgctccagtta agtgacaatgacccgagaaagcaaggagatggaaaactacagggaagtcctggtgatagt ccaaaatcttttcaaatgtcttcctccaaagttagtgcagtcaggctaaaatttgaacaa gaggctcagaggcaagataggggaagttcagggagtcaaaatcaaaaccctccaataaga aagctccaggaaactagactacctgtgtatcagatgttttctggctctagatctcaaaaa gcacctgacagtccagcaaaccaaagaaaatgcaaagagactgagtcaaataagtcatca cccaagcatgagaccagtggcaaagatcaggaagagaataagtctttgaaaacatgggag agacagggctatgggcagtgtaaacctcagtccccaaaactttccaattattcagctcat gattccacaaaagattgcagtagtgattcccaaagacaagaaacaacaaagaaaataatc tatacagaatttgttgtcagagaaagtccaagtaccaatgatggtctaaaaaaaaactcg gaatcgcaaattcctgtaagaaaatcgtctaatttttcagaaaaccccaaatccacctct ttaaaattagaagaaccaagtgaaagacctgggcctcatacccctactttaggtagaaat cggttacacagtagctctgaatccaataggtctactcgtggatcatccttagggaaatcc acagtctcctcagagagtagccagtcaaatgtagtatgtaatggcgttgatgatgatgat gatcaagtgcagtacttggatcaagcaactcctgtagttgtgactgagggcttcaaagat attaaacccttgccagtgtatgtcagcatccaagtaggaaagcagtatgagaaagaaaca agttcagggcagctggggacatacaaaaagattgtgagtcaagagagcaggacagtgcat gaaacgagaggtgcagtttacagtgtcaagcaaaaacagtctccttctcctcaaggaagt ccagaagatgacactttagaacaggtaactttcatggacagctctgggaaaagccctgta acccctgaggccccaagctcagaagagctgagcctgacatcccgaacaccagactctgtg ataggttttatgaccagcatgccaagcactatcccagaggaatctgaggaggaagatgga aagaccttcatctataaagagccattaaaagcaaaacccaaaccagcctctccagagaat cacagtaaaaagcaggaaggagaaagagggaagtcaaaggagaaaagagtcgcttatata gagtttccgccccctcctccattagaggccgagcagtgcagtgctgagaaaaggtctgga tgtacttcctctgaaacggagacagagatgattgaggtaaatcttcaagaagagcatgat agacaccttttagccgagcctatcattcgagtccagcctccttctcctattcccccgggg gctgataacagtgactctagtgatgatgagtctgtcttccatcccgttcctgtcaaaaag tacaccttcaaaatgaaagaagaaagcgagaagcgtcaaaaacccaaaaagtcagagaaa aatggagctaaagaatctggggttaatggtggaaagggagaggatgctgaattggaacaa aatggaaatgatcagtccatcactgactgctcaatagcaacaactgctgagttctcccat gacacagatgctactgagattgactctttagatggatatgatcttcaggatgaagatgat ggactaagtgaagaccctaaaacatcaagtttgtccaatgatgggaaagctattgaccgt tcatttaatcagtccaagcttgaagtgatagaagaggagaaatgtgaggaaggaagtgac aatggaaagactaaaagtggcacatctggtgcgaaagctagtggagaaaaaaaagactat acccttgaaggaagacacccggataggaagggctttggggagaactattttggataccaa atccaagatgagctgaattcaacctttaaaactgttgctaccaaaggtttggactttgac ccttggtcaacaaaaggggttgataatgaagggctttttgagtccaaagcaaaagaagag gaccccaaaccttacagtttgtcggctgaagaaaaatcacaggctacaacacctgacaca acccctgctcgaacaccaactgatgagagcacaccgactagtgagcctaaccccttccct ttccatgaagggaagatgtttgagatgacacgcagtggtgctattgacatgagcaagcgg gactttgttgaagagaggcttcagtttttccagattggtgagcattcctctgaccctata acaggggaaaaggggagagggggaaagatcctgggggtaccttcctctcagtcgaaaact ggggagaggtccacagtagatggaaagatgacagttgtagacactaccttagacagcagc agcactagaccaacaacaccagcaacaactgcagcgaaatacaaccctgcacagcctggc agtgacataggttgtgccattactgatattcctgcctgtgaagccatagctgagactgcc tcttcatgcacaatcacggcctctaaggttgattccaaattacgaactcctattaaaatg ggcatagctgcctctataactgtgaaaaaagactcaggggatctcacaaactgcaaagct gagttgtcagaaggtcaggtggtgccagaatacattagtatagagggtcagtcttcagag aaacagtctagcagtcattctgagcttagaaaagaaaaaaaagactacccatctgaaaac tgcaacaacaataataacctggaatcctccagtgtccaggccaactatattcagtgtggc agtttagtgtttaatttgcagtcctcctctgagcccaccttacagaaagctagcaggata gaaactctgtgctgtaaagataagaacgagagagtagaagtgcccagcggcagtcaggct caagagcagaagaccgaaacggttaaggagagtgaggcaaagcagcccaggtcgaggctt ccagtcaaagcatcaggctggtcatttcacacacaaggaactgccattgggaagcagaaa cccaaacaagcagtagcaggtgaggtcaggaaaagaggagaaccagtgattgccaaagta gagcctaggtcaaggataccagtcaaagacgttaaaaagagtagtcctgctgctacagct agcttacctgtctcagttcgtattacctcacacccagtaaagacactgaatacagggaga gcagtcatacaactgcccacaaggcaaccgcagaaggacaggcatcaattcagcagtgtc accagtgagggagcatctagacagaacagacaggataaccctagtgaactttgtaagcgc accattgaatactttaaagacattagcggggagacgctaaagttggtggaccgcctgtca gacgaggagaaaaagacgcaaacagaacagtcggaggaagacagcacctcccgaagcacc tctctgtcggacgcctcccagccttcccagccctcccagccctcccgctcatccaggtct ggtagaggttcgagggctgaggccggggccgcgtccgtaagggcaaaggtggcgacgacg gacaggggttccggcagtgagaggagcaggaggagtaggcggactggtgggaaggagggc agtcagggactcacagggtctcgaacgcctcccatcgcggagatcaagcctagtccccaa agtccttgtgagcgaacagacttgcgcatggctatcgttgcagatcacctggggctcagc tggacagagctggctcgagagatgaacttcacagtggacgagatcaaccacatcagactt gagaaccctaactctctgacagcacagagcttcatgctacttaagaaatgggtcagtcgt gaagggaaaaatgccacaacggatgccttatctgaagtgctgaccaaagtcaatcggatg gatattgtgactttgctggagggcccaatattcgactatggtaacatttcaggcacgaga tgttttgccgatgataacgctgttttccgggatcaggctgatgattatcagagcattcta gccgagctgcagtcccctgccactctgcagcccagcccccacttcctggagcctgaactc cctgccacccccaacccttccctcgcccagcatcagcatcttcattaccccgaaccagac aactcttgcaatcaccctcagttcgcggattggagtccagttgttgatccttgtagtaaa gaaccagacagcccgcctaagagtccccccaggccctgtgagcttgccctgcctgcccca acctttgatcttcccgacccgattcctcctaaggtcagaaagccccacattgctttgaac gaccagcttcttttgagtgaagaggaggacagaccttttcaagaaatggagcccaccctc aagcccagatcccagtcctttccgacaatgtgcgaattggacatcgacatggcgttctct acttcttctccttcgctgtcatccatgtcatcgataaccccgtcgtcccctgatagatca tgtataggtacgcggttgggaaacgcctcagatggggcacaagaggatataggtcagaca ggcggtcaagtggaagtgaaagaagaaatcgagaaagtggttgagattgtttcgacgcag ttggtagagaggaacggattagtagagaagttggtcacgcaggaattgattaaaaatgtg gaaagaaagtgtgagatggttgcaaaagacaggtctcagctggtagaggaagggatcatt ttgctggaaccgaagaggtccgcagagcaggataaagataatgtcaatgagcaacacgat gaggttcgagatggcagtagaacagcagcacgtgaggaagagaaggctgaagatgaactc aatgtcttaatgcagcatgttagtctaccagataaagtagtcaaagaggctgttggtcaa tcgctggatgttggggaaagagtacaagtgaaggaaaaagtggaagatcctgagtcagaa ctgcagtctaaagatggacaagacatctgtgacacattagaaggggcaacagaacgccag actttgtctgacctttcccctcaagcttgggttaaagtgcttgagcaactgcagccctat gagtctggatccaatgagaaagaagagaagcagagaggcagagaaattccagaggaggca ttaggatctctgttggaggaggtgaataaagaaggctcagaggagaaggagaaggaggag gaggaggaggacgacgaaaaggtgactcaatccaggaatcaggagagacttgaagaggtt gaacatgcagaaaaaaacatatgttcactttcaggatggcacagcgactcatccagtgtg aatgttgagccgccgactccgggccgcagtgtcagctcagacttgctcgacaagcaggaa agtcaggaaaactctagtgagtccatcacctcctcatctagagctgaatcagggaggtcc agacctaacggtgataactcgaaacactcacctcaggacgcctcatcagactcatctaac ggcagaaaagacgggacgccagtgtcggagaaaaaagtgcaggttagtgtagattctggt tcagaggaagaacagactgtaaccaccagaatctacaggcggcgtctcattataaaggga gaagaagcaaaaaacatcccgggcgagtctgtgacagaggagcactacatggaccacgat ggtaacctcatcagtagaaaagtgatcaggaaggtaattcggcgagtctcagctcccact ccagaaaaccaaggaggtgacaggtggcacagtgaccttcaccacagtcccactcagcag gattatggccgggggatggagcgaggaaatgcagacgatcaggggacaaaaagcacctct cgtagggatgggcttggtttagcaggcttacaggaactacgttag

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