Poecilia reticulata (guppy): 103481989
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Entry
103481989 CDS
T05149
Symbol
top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
pret
Poecilia reticulata (guppy)
Brite
KEGG Orthology (KO) [BR:
pret00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pret03032
]
103481989 (top2a)
03036 Chromosome and associated proteins [BR:
pret03036
]
103481989 (top2a)
Enzymes [BR:
pret01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
103481989 (top2a)
DNA replication proteins [BR:
pret03032
]
Eukaryotic type
DNA Topoisomerases
103481989 (top2a)
Chromosome and associated proteins [BR:
pret03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
103481989 (top2a)
Centrosome formation proteins
Centriole proteins
103481989 (top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
Motif
Other DBs
NCBI-GeneID:
103481989
NCBI-ProteinID:
XP_008436082
LinkDB
All DBs
Position
LG19:complement(23232202..23251907)
Genome browser
AA seq
1579 aa
AA seq
DB search
MEGRGKKQAFLENKPLEKTKKDPKRLSVERIYQKKTQLEHILLRPDTYIGSVEPVSQQMW
VYDEGVGLNCRDVTFVPGLYKIFDEILVNAADNKQRDKSMSCIRVNIDVENNTISVWNNG
KGIPVVEHKVEKVYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVETA
CKESKKVFKKTWYDNMGRAGDASIKPFEGEEYTCITFMPDLAKFKMSILDKDTVALMTRR
AYDIAGSSKGVKVFFNNKRLPVSGFRSYVDMYVKDKVDELGSPLSVVHEVVNERWEVCLT
MSEKGFQQVSFVNSIATTKGGRHTDYVADQVVGKLIEVVKKKNKAGVTVKPFQVKNHMWL
FVNCLIENPTFDSQTKENMTLLQKKFGSTCPLGDKFIKQATGCGIVESIMNWVKFKAQSQ
LNKKCSAVKHTKIKGVPKLDDANDAGGKNSIGCTLILTEGDSAKTLAVSGLGVVGRDRFG
VFPLRGKMLNVREASHKQIMENAEINNIIKILGLQYKKNYSDPESLKTLRYGKIMIMTDQ
DQDGSHIKGLLINFIHHNWPSLLRHNFLEEFITPIIKVSFKKSQLSFYSIPEFNAWKEGQ
PNHRSWKIKYYKGLGTSTSQEAKEYFLDMQRHRIPFKYSGPADDEAITLAFSKKKVDERK
EWLTNFMNNRRQRREHNLPEDYLYGQSTKSLSYNDFVNKELVLFSNSDNERSIPCLVDGL
KPGQRKVLYCCFKRNDKREVKVAQLAGSVAEMSAYHHGEVSLMMTIVGLAQNFVGSNNMN
LLQPLGQFGTRLHGGKDSASPRYIFTMLSPLARLVFPAVDDNLLKYNYDDNQRVEPEWYI
PIIPTVLINGSEGIGTGWASKITNYDIREIISNIHRMLNGQEPLPMLPNYKNFRGTIEQV
MDNQYMNSGEVAIIDSTTIEISELPVKTWTQAYKENVLEPMLNGTEKVPPLITDYKEYHT
DTTVRFVIKMSEEKLREAEAAGLHKVFKLQSPLTCNSMVLFDHVGSLKKYESVQDILKDF
FELRMKYYVLRKDWLAGMLGAESAKLSNQARFILEKIQGTLVIENKPKKELIRMLQKMGY
DSDPVKAWKRAQEKNEEELEDEDEEGAEKEDDSGPDYNYLLSMPMWFLTKEKKEELCRQR
DAKMTELNTLKKKSPEDLWREDLAVFSEELERIEAKEKESDGVPVKGAGKGKAVKVKKET
LPTPQGRRVVPRITSTMKAEANRKADLKKGEGRRGRKVKTEDVVMQMEFDEEVENVEPEE
MGLASRLAKKAKPEPKQRATSKVAKQTTLQFKPVAKKPKKNPWSDDESEGSSGSDMEAEE
AAAPRERMQRKTKAPVKYSLSDSEDEFDDWGKKSSPKRKSVISDEDSSFALGPSTASDSD
VYSPPPPPKAPEPAKKTVKSKTTVKKTETKSSVSSDDEAPASKPPAQQKPKETAAKKAPA
KKPTASKKKTSDEKQPSILDALSKPKASSKTAPKKIPTFGSSDSEDTGSIPAKKQSKAAV
KRKQVISDESDSSSGDLMSRLKAKPQAAVKKSKKWMEDDNFQISDQEEEALVAVAPRDKP
SRARKPVTYNMDSDSDEDF
NT seq
4740 nt
NT seq
+upstream
nt +downstream
nt
atggagggtagaggaaaaaaacaggcctttttggaaaataagccgctggaaaagacaaag
aaggatccgaagcgactgtcggtggagaggatctaccagaagaagacgcagctggagcac
attctgctcaggccagacacctacataggctctgtagagcctgtcagccaacaaatgtgg
gtgtatgatgagggcgtaggactgaactgccgcgacgtgacgtttgttcctgggctctac
aagatttttgatgagatactcgtaaatgcagccgacaataagcaaagggacaagagcatg
tcctgcatccgagtcaacatcgacgtggagaacaacaccatcagcgtgtggaataacggg
aaggggatcccagtagtggagcacaaggtggagaaggtctacgtgcctgcgctcatcttt
gggcagctcctcacgtccagtaactatgacgacgaggagaagaaggtcacgggtggccgt
aacggatacggcgccaaactttgcaatatcttcagtacaaagttcaccgtggagacggct
tgtaaggagtccaagaaggttttcaagaagacctggtacgacaacatgggcagagcggga
gacgccagcatcaaaccttttgaaggagaggagtacacttgcatcaccttcatgccggac
ctggccaagtttaagatgagcatcctggacaaagacacggtggctctgatgaccaggaga
gcgtacgacatcgctggctcctccaagggagtcaaagtgttcttcaacaacaagaggctg
cctgtgtcaggttttcgcagctatgtggacatgtatgtgaaggacaaggtggacgagctg
ggcagtcccctctctgtggtccatgaggtggtcaatgagcgctgggaggtctgtctcacc
atgagcgagaaaggcttccagcaagtcagcttcgtcaacagcattgctaccacaaaggga
ggcagacacacagactatgtggctgaccaggtggttggaaagctcatcgaagtggtgaag
aagaagaacaaagccggcgtgactgtcaagcctttccaggtgaaaaaccacatgtggctg
tttgtcaactgcctgatcgaaaaccccacttttgactctcagacgaaagagaatatgact
ctactgcagaagaagtttggctccacttgtccactgggtgacaaattcataaaacaggcc
acaggatgtgggatcgtggaaagcatcatgaactgggtgaagttcaaagctcagtctcag
ctcaacaagaaatgctcagcggtgaagcacaccaagatcaaaggagtcccgaaactggac
gacgccaacgatgcaggtgggaaaaactccattggctgcacattgatcctcactgaggga
gactcagccaagacgctggctgtgtctgggctgggagtggttggacgggaccgcttcggt
gtgttccccctcaggggaaagatgctcaacgtccgggaggcttctcacaaacagattatg
gaaaatgctgaaatcaacaatatcatcaagatcctcggtcttcagtacaagaaaaactac
agtgacccagaatccctgaagacgctacgttacgggaagatcatgatcatgacagatcag
gatcaagatggatcccacattaagggcttgttgatcaacttcatccatcacaactggccg
tcgctgcttcgccacaactttctagaagagttcatcacacccatcatcaaggtatctttc
aagaaaagccagctgtccttctacagcatccctgaattcaacgcatggaaggagggccag
cctaaccacagatcctggaaaatcaaatactacaaaggtttgggaaccagcacatcacag
gaagccaaggagtacttcttggatatgcagagacatcgtatcccctttaagtattctggc
cctgcagatgacgaagctatcacccttgcctttagcaagaagaaggtggatgagaggaaa
gaatggctcaccaacttcatgaacaacaggcgccagcgcagggagcacaaccttccagag
gactacctgtatggtcagtcaacaaagtccttgtcttacaatgacttcgtcaacaaggag
ctcgttcttttctccaactctgacaatgagaggtccattccttgcttggtggatgggttg
aaaccaggacagaggaaggtgctgtactgctgttttaagaggaatgataaacgggaggtg
aaggtggcccagctggccggctcagtggctgagatgtcagcctaccaccatggggaggta
tctctgatgatgaccatcgtcggtttagcccagaactttgtgggcagcaacaacatgaac
cttctgcagcctctgggacagtttggaaccaggctgcacggcggcaaggactcagccagc
cctcgatacatcttcaccatgctcagccctttggctcgcctcgttttcccagcagtggac
gacaacctgctcaagtacaactatgacgataatcagcgcgttgagcccgagtggtacatt
cccatcatccccactgtgctgattaatggttctgaaggtatcgggaccggctgggccagc
aagattaccaactacgacatccgggagatcatcagcaacattcaccggatgctcaatggc
caggaaccgttgcccatgcttccaaactacaagaacttcagaggcacgatcgagcaggtg
atggataaccagtacatgaacagtggcgaggtggccatcattgattccaccaccattgag
atctctgagttacccgtcaaaacctggacccaggcctacaaggagaacgttctggagccg
atgttgaacggaacagagaaggttcctcctctgatcactgactataaggagtaccacacg
gacaccacagtccgcttcgtcatcaagatgtctgaggagaagctgagggaggcggaggct
gccggcctccacaaagtcttcaagctgcagagcccgctcacctgcaactccatggttctg
tttgaccatgtgggcagcttgaagaagtacgagtctgttcaggatatcctcaaagatttt
tttgagttaaggatgaaatactatgtcctgaggaaggactggctggccgggatgctcgga
gcagaaagcgccaaactgtcaaaccaggcccgtttcatcctggagaaaattcagggcacc
ttggtcattgaaaacaagcctaaaaaggaactgattcgcatgcttcagaaaatgggctac
gactcggacccagttaaagcttggaaacgggctcaggaaaagaatgaggaggagttggag
gacgaagatgaggaaggagcagaaaaagaggatgacagtggacccgactacaactacctg
ctgagcatgcccatgtggttcctcaccaaggagaagaaggaggagctgtgccgacagagg
gatgctaagatgactgagctgaacaccctgaagaaaaagagcccagaagacctgtggagg
gaggacctggctgtgttctcagaggagctggagcgcattgaggccaaagagaaggagagc
gacggcgtcccagtgaagggggccggcaaaggcaaagctgtgaaggtgaagaaggagacg
ctgcccacaccgcagggccggcgggtcgttccccgcatcaccagcacgatgaaggccgag
gccaacaggaaggctgacctgaagaaaggagagggcaggagaggcaggaaagtcaagacc
gaagacgtggtgatgcagatggaatttgatgaggaggtggagaacgtggagccagaggaa
atgggcttggcgtcacggctggccaagaaagccaaaccagaacccaaacagagagccaca
tcaaaagttgctaagcagaccactcttcagttcaagcccgtcgccaagaagccaaagaag
aatccgtggtcggacgatgagtctgaaggctcgtcaggaagtgacatggaggcagaggaa
gcggcggcccccagggagcgcatgcaacgcaaaactaaagccccggtgaagtacagcctg
tcggacagcgaagatgaatttgatgactggggaaagaagagttccccaaagaggaagtct
gttatcagtgatgaggattcgagcttcgccctggggcccagcaccgcgtcggacagcgac
gtctactccccacccccccctcccaaagctccagagccagcgaagaagacggtaaagagc
aaaacgacggttaaaaagacagaaaccaagtcatctgtttcctctgatgatgaggctcca
gcatccaaacctccagctcaacagaaacccaaagagacggcagccaaaaaagctccagcc
aagaaacccaccgcctccaagaagaagacatcagatgaaaagcagccttctattctagat
gctctctccaaacccaaagcttcctccaagaccgctcccaaaaagattcccacttttggc
tccagcgactcggaggatacagggagcattccagcaaaaaagcaaagcaaagccgctgtg
aagcggaagcaggtgatcagcgacgagtcggacagcagctcaggcgacctcatgtcgcgt
ctcaaggctaaacctcaggctgccgtaaagaaatcaaagaagtggatggaagatgacaac
ttccagatttcagaccaagaggaagaggctcttgttgccgtggcacctcgggataaaccc
tcccgtgctcggaaacccgtcacctacaatatggactcggactccgatgaagacttttaa
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