Porifericola rhodea: PZB74_07445
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Entry
PZB74_07445 CDS
T09201
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
prho
Porifericola rhodea
Pathway
prho00260
Glycine, serine and threonine metabolism
prho00261
Monobactam biosynthesis
prho00270
Cysteine and methionine metabolism
prho00300
Lysine biosynthesis
prho01100
Metabolic pathways
prho01110
Biosynthesis of secondary metabolites
prho01120
Microbial metabolism in diverse environments
prho01230
Biosynthesis of amino acids
Module
prho_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
prho_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
prho00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
PZB74_07445 (thrA)
00270 Cysteine and methionine metabolism
PZB74_07445 (thrA)
00300 Lysine biosynthesis
PZB74_07445 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
PZB74_07445 (thrA)
Enzymes [BR:
prho01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
PZB74_07445 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
PZB74_07445 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT
NAD_binding_3
ACT_7
4HB_MCP_1
TfoX_C
Motif
Other DBs
NCBI-ProteinID:
WKN33176
LinkDB
All DBs
Position
complement(1819791..1822280)
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AA seq
829 aa
AA seq
DB search
MKLLKFGGTSVGSAESIKTVAEIVATYHREQIKCAVVVSAMSGITDKLIAISEKAASGDE
SYLELLKELEKHHFDTARTLINVHAQSRVFAYLKTLINELDDLLHGAFLLKERSPRTLDL
VLSFGERLSAYLISQYMKELGIDADFLDARKVIRTDANFNAAKVDFESTNQNINEYFTAN
KALQIITGFVASTADNETTTMGRGGSDYTASIFGAALNAEEVEIWTDVDGVMTADPRQVK
NAFSLEAISYLEAMEMSHFGAKVIYPPTIQPLLNKNIPLRIRNTFNREFPGTVISRNPYA
TQNTPEGNEKLMAVKGISSIKEVALLSLQGSGMIGIPGISSRLFGALARRKINIIIITQA
SSEHSISFAVSPTDAKLAQEAMDEEFAIEISTGKIDKAIVEQHLSIVAIIGENMRQTPGI
SGKLFSALGRNGINVRAVAQGSSEVNLTVVISQRNLSKALNTVHEAFFLSETKTLNVFMA
GLGLIGSTLLKQIAQQGSTLFENRLLRINFIGIINSRKMLINEAGIDTNHWQALLEQDGS
ASDMGTFVHRLKELNLPNSVFIDCTSSDYVIKYYQEVLQSAVSIITPNKLANSGTYKTYQ
QLKQTAMRAGVKFLYETNVGAGLPVIRVLQDLKDSGDKIYKIEGVLSGTLSYIFNSFQEG
RKFSEVVKEAQQKGYTEPDPREDLNGMDVARKILILSREVGLTLEPEDVEIQNILPQQCL
EAPDVESFFQTLESIDDEMEAKRKKAAEEGCKLRFIAILEDGKASVQLQEVGETHPFYSL
SGSDNIISYHTARYKERPLVVKGPGAGAEVTAAGVFAEVISISNFLYQQ
NT seq
2490 nt
NT seq
+upstream
nt +downstream
nt
atgaaattactgaagtttggaggtacatcggtcggctctgccgaaagcataaaaactgta
gctgagattgtagccacttatcatcgcgagcagataaagtgcgcggtggtagtatctgcc
atgagcggtattactgataagcttattgctatcagcgaaaaagctgccagtggggatgag
agctatctggaactactaaaagagctggaaaagcatcattttgatacagcccgaacgcta
attaatgtgcatgcccagagcagagtttttgcttacctcaaaaccctcattaacgaacta
gacgacctattacacggggcctttttgcttaaagagcgctctcctcgcaccttagacctt
gtactaagctttggcgagcgcttatcagcttacctgataagccagtacatgaaagaactg
ggcattgatgccgactttttagatgctcgcaaagttatacgtactgatgctaactttaat
gcagctaaagtagactttgagtctacaaatcagaatatcaatgaatactttaccgctaac
aaggcactacaaattattacaggttttgtagcctctactgccgacaatgaaactaccact
atgggtagaggaggctctgactataccgcctctatttttggcgctgcgcttaatgcggaa
gaagttgaaatctggacggatgttgatggtgtaatgacggcagatccccgtcaggtgaaa
aatgctttctctcttgaggctatatcttacctggaagctatggaaatgtctcactttggt
gccaaagtgatatacccgcctactatacagcctctgcttaataaaaatattcctttaaga
atccggaatacttttaacagggagtttcctggtactgtaattagccgaaacccttatgcc
acccaaaacactcctgagggtaacgaaaagcttatggcggttaagggaatttcttcaatt
aaagaagtagccctcctgagtctgcaaggtagtggcatgataggcatcccgggtatttct
tcacgtttgtttggagcattagccagaaggaaaataaatattatcattattacacaggct
tcttctgaacattctatcagctttgccgtgagccccacagatgcgaaactggcccaggaa
gccatggatgaagagtttgctattgagataagtaccggtaaaattgataaagctattgta
gagcaacacctgtctattgtggcaattattggcgaaaatatgcgccagacacctggtata
tcgggtaagctttttagcgctttaggcagaaacggcatcaacgttcgtgccgtagcacag
gggtcctctgaggtaaaccttacagtagttatttctcagcgcaacctttccaaggcgcta
aatactgtgcacgaagccttcttcctttctgagaccaaaacccttaatgtgtttatggca
ggcttaggcttaattggtagcaccttgcttaagcagatcgctcagcaagggagtacactc
tttgaaaaccgcctcctccgcattaactttattggtattatcaacagccgcaaaatgctt
attaacgaagcaggcattgataccaaccactggcaggctctactcgagcaagatggttct
gccagcgatatgggtacttttgtgcatcgtcttaaggagcttaaccttcctaatagtgta
tttatagattgtacttccagtgactatgtgattaaatactaccaggaggtacttcagtct
gctgtttctattattacgcctaataagctagccaattcaggcacttacaaaacttatcag
cagctcaagcaaaccgccatgcgtgcaggagttaagtttttgtatgaaaccaatgtgggt
gcgggtttaccagtaatacgggttctacaggacctcaaagatagcggtgataaaatttac
aaaatagagggggtactctccggtacattgtcttatatattcaattcttttcaggaaggg
cgtaagtttagcgaggtagtaaaagaagctcagcagaaaggctataccgaaccagaccct
cgtgaagacctgaacggtatggatgtagccagaaagattctcatactttcgcgcgaagtg
ggtcttactctagagccagaggacgtagaaattcagaatattcttcctcaacaatgtctt
gaagctccagatgtagagtcattctttcaaaccctggagagcattgacgatgagatggaa
gctaaaaggaagaaagcagctgaagaaggctgtaaactacgctttatagccatactggaa
gatggtaaagcttctgtccagttgcaggaagtgggtgaaacacatcctttctattctctc
tctggcagcgataatatcatttcatatcacaccgcccgatataaagaaaggcctttggtt
gtaaaaggaccaggagccggtgcagaagttacggcagcaggtgttttcgcagaggtaatc
agcatcagcaacttcctttaccaacaataa
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