Providencia rustigianii: NCTC6933_00725
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Entry
NCTC6933_00725 CDS
T06047
Symbol
thrA
Name
(GenBank) Aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
prj
Providencia rustigianii
Pathway
prj00260
Glycine, serine and threonine metabolism
prj00261
Monobactam biosynthesis
prj00270
Cysteine and methionine metabolism
prj00300
Lysine biosynthesis
prj01100
Metabolic pathways
prj01110
Biosynthesis of secondary metabolites
prj01120
Microbial metabolism in diverse environments
prj01230
Biosynthesis of amino acids
Module
prj_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
prj_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
prj_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
prj_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
prj00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
NCTC6933_00725 (thrA)
00270 Cysteine and methionine metabolism
NCTC6933_00725 (thrA)
00300 Lysine biosynthesis
NCTC6933_00725 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
NCTC6933_00725 (thrA)
Enzymes [BR:
prj01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
NCTC6933_00725 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
NCTC6933_00725 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
VEB63804
LinkDB
All DBs
Position
1:745072..747531
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANDERVLNVADIAESKLADGQVALVLSAPAKITNHLVAMIEKTVAGQDV
ITHVNDAEMIFANLLKGLKDKLPGFEYDKLKKLTEHEFAQIKQVLHGITLLGQCPDSINA
AIICRGEKLSIAIMESVLKARGHKVTVINPVESLLAKGHYLESTVDINESTKRIAELNIP
KDHFILMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRLV
PDARLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTTNPSAPGTLIGDGQT
DVSTPVKGITNLNNMAMINVSGPGMKGMVGMAARIFSVMSRKGISVVLITQSSSEYSISF
CVPQNELRRARTALEEEFYLELKDGVLDPLDVMEQLAIISVVGDGMRTLKGISARFFSAL
TRGNINIVAIAQGSSERSISAVIANESATTAVRLCHQMLFNAEQVIEAFIVGVGGVGNAL
IEQIHRQQQWLKQKHIDLRVCGIANSRAMLTNMQGIDLDNWKAELAEAKEPFSLSRLIRL
EREYHFLNPVIIDCTSNQEIAEQYVNFLKDGFNVVTPNKKANTLSMDYYHQLREASENSK
RKFLYDTNVGAGLPVIENLQNLLNAGDELVHFSGILSGSLSFIFGKLDEGMSLSEATTLA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYKLELEDIEIESVLPADFDSSGNVTEFMA
RLPQLDAPFAERIKAAEAEEKVLRYVGLIEEGRCQVKIVAVDGNDPLFKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADMLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgcttaaatttggcggtacttcggttgcaaatgacgaacgagtactgaacgtt
gctgacatcgctgaaagcaaattagctgatggtcaagtggctctggtgctatctgcacca
gcaaaaatcactaaccatctcgttgcaatgattgaaaaaacagtcgcgggtcaggatgtc
atcacgcatgtgaatgatgcagaaatgatttttgctaatctgttaaagggcttgaaagat
aagctacccggcttcgaatatgacaagttaaaaaaactaactgaacacgaattcgcgcaa
attaaacaagtactgcatggtattactcttcttggacaatgtcctgacagcattaacgcc
gcaattatctgtcgtggtgaaaaactctctattgccatcatggaatctgttttaaaagcg
cgtggccacaaagttactgtgataaacccagtcgaaagcttgcttgcaaaagggcactat
ttagaatccacagttgacatcaatgaatcaacaaaacggattgccgaattaaatatacca
aaagaccattttatcttgatggcaggtttcaccgcagggaatgataaaggtgaactcgtg
gttttagggcgtaacggctctgactattctgcggcggtattagcggcgtgcttacgcgct
gattgctgtgagatttggactgatgttgatggtgtttatacctgtgacccacgtttagtg
cctgatgcaagattactcaagggaatgtcgtaccaagaagcgatggagctttcatatttc
ggcgcgaaagttcttcatcctcgcactattgcaccgattgctcagttccaaattccttgc
ttgatcaaaaacaccactaatccgagtgctccgggaacgttaattggggatggacaaacg
gacgtcagtaccccagttaaagggatcactaacctgaataatatggcgatgatcaacgtc
tcaggcccgggaatgaaaggcatggtgggtatggctgcgcgtattttttcagtcatgtcg
cgtaaaggaatctccgtggtactgatcacccaatcgtcctcagaatacagtatcagtttc
tgtgtgccacaaaatgaacttcgacgagcacgtactgcgctagaagaagagttttattta
gagctgaaggatggggtattagacccattagatgtgatggagcaactggctatcatctcc
gttgtgggtgacggtatgcgtacgctaaaaggtatttcagcgcgtttcttctcagcattg
actcgtggcaatattaatatcgtggcgattgctcaggggtcctctgagcgctctatttcc
gcggttattgccaatgaatcagcgacaacggcggtacgcttatgtcaccaaatgctcttc
aatgcagaacaagtgatcgaggcctttatagtgggtgtcggtggggttggtaatgcgctg
attgagcagattcatcgccagcaacaatggctaaaacagaaacatattgacctgcgtgtg
tgcggtatcgcgaactcaagagcgatgctaactaatatgcaaggtattgatttagataac
tggaaagcggaactcgctgaagcaaaagagccatttagtcttagccgcttgatccgctta
gagcgtgaatatcacttcttgaatccagtaattatcgactgtacatcaaatcaagaaatt
gctgagcagtatgttaatttcttaaaagatggttttaacgttgtgacgccgaataaaaaa
gccaacacattgtcgatggattattaccatcagctacgtgaagcatcagagaattcgaaa
cgtaaattcttatatgacactaacgttggcgcaggtttaccggtaattgagaatcttcaa
aacttactcaatgctggggatgagctggttcatttcagcggtatcttgtctggctccctt
tcgtttattttcggtaaattagacgaaggcatgtcattgtctgaagcgacaacattagca
aaagagaaaggctttacagagccggatcctcgtgatgatttatccggtatggatgtagca
cgtaaattattaattcttgcccgtgaagcgggatataaattagaactggaagatattgaa
attgaatcagtattacccgctgattttgacagttcaggtaacgtgactgaatttatggca
cgtttaccccagctagatgccccatttgctgagcgcataaaagccgcagaggcagaagaa
aaagtgttacgctatgtcggtcttatcgaagaaggtcgctgtcaggtgaaaattgtcgcc
gttgatggtaacgacccactgtttaaagtgaaaaatggcgaaaacgcactggcattctat
acgcgctattaccagccaattcctttagtgttaagaggctatggtgccggtaatgatgta
actgcggcgggtgtatttgcggatatgctgcgtaccctatcatggaaattgggagtttaa
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