Phodopus roborovskii (desert hamster): 127215359
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Entry
127215359 CDS
T08852
Symbol
Erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob01521
EGFR tyrosine kinase inhibitor resistance
prob01522
Endocrine resistance
prob01524
Platinum drug resistance
prob04010
MAPK signaling pathway
prob04012
ErbB signaling pathway
prob04020
Calcium signaling pathway
prob04066
HIF-1 signaling pathway
prob04151
PI3K-Akt signaling pathway
prob04510
Focal adhesion
prob04520
Adherens junction
prob04530
Tight junction
prob05200
Pathways in cancer
prob05205
Proteoglycans in cancer
prob05206
MicroRNAs in cancer
prob05212
Pancreatic cancer
prob05213
Endometrial cancer
prob05215
Prostate cancer
prob05219
Bladder cancer
prob05223
Non-small cell lung cancer
prob05224
Breast cancer
prob05226
Gastric cancer
prob05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
127215359 (Erbb2)
04012 ErbB signaling pathway
127215359 (Erbb2)
04066 HIF-1 signaling pathway
127215359 (Erbb2)
04020 Calcium signaling pathway
127215359 (Erbb2)
04151 PI3K-Akt signaling pathway
127215359 (Erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
127215359 (Erbb2)
04520 Adherens junction
127215359 (Erbb2)
04530 Tight junction
127215359 (Erbb2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
127215359 (Erbb2)
05206 MicroRNAs in cancer
127215359 (Erbb2)
05205 Proteoglycans in cancer
127215359 (Erbb2)
05230 Central carbon metabolism in cancer
127215359 (Erbb2)
09162 Cancer: specific types
05212 Pancreatic cancer
127215359 (Erbb2)
05226 Gastric cancer
127215359 (Erbb2)
05219 Bladder cancer
127215359 (Erbb2)
05215 Prostate cancer
127215359 (Erbb2)
05213 Endometrial cancer
127215359 (Erbb2)
05224 Breast cancer
127215359 (Erbb2)
05223 Non-small cell lung cancer
127215359 (Erbb2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
127215359 (Erbb2)
01524 Platinum drug resistance
127215359 (Erbb2)
01522 Endocrine resistance
127215359 (Erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
prob01001
]
127215359 (Erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
prob04147
]
127215359 (Erbb2)
04090 CD molecules [BR:
prob04090
]
127215359 (Erbb2)
Enzymes [BR:
prob01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
127215359 (Erbb2)
Protein kinases [BR:
prob01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
127215359 (Erbb2)
Exosome [BR:
prob04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
127215359 (Erbb2)
CD molecules [BR:
prob04090
]
Proteins
127215359 (Erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
DUF5849
Motif
Other DBs
NCBI-GeneID:
127215359
NCBI-ProteinID:
XP_051031722
UniProt:
A0AAU9YLP9
LinkDB
All DBs
Position
Unknown
AA seq
1256 aa
AA seq
DB search
MELAAWCRWGLLLVLLSPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANASLSFLQDIQEVQGYMLIAHNQVRQVPLQRLRIVRGTQLFEDKYALAVLDNR
DPLDNVTSTTGSTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDTVLWKDVFRKSNQLA
PVDIDTNRSRACPPCAPACKDNHCWGESPQDCQTLTGTICTSGCARCKGRLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTTCP
YNYLSTEVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLRGARAITSAN
IQEFAGCKKIFGSLAFLPESFDGDPASGIAPLQPEQLQVFETLEEITGYLYISAWPDSLH
DLSAFQNLRVIRGRILHDGAYSLTLQGLGIRWLGLRSLQELGSGLVLIHRNTHLCFVHTV
PWDQLFRNPHQALLHSGNQPEEGCVHKGLACYPLCAHGHCWGPGPTQCVNCSHFLRGQDC
VEECRVRKGLPREYVSGKHCLPCHPECQPQNNTETCVGSEADQCTACAHYKDSSFCVARC
PSGVKPDLSFMPIWKYPDEEGICQPCPINCTHSCVDLDERGCPAEQRASPATSIIATVVG
ILLFLVIGVVVGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPSSPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGTGSTAHRRHRSSSTRSGGGGELTLGLEPSEEEPPRSPLAPSE
GAGSDVFDGELGMGVSKGPQSISPHDLSPLQRYSEDPTLPLSPETDGYVAPLACSPQPEY
VNQPEVRPQSPLTPEAPLPPVRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAP
RGGTASQPHPSPAFCPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3771 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgtcgctgggggcttctcctcgtcctcctgtcccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagttgcggctccctgccagtcctgag
acccacctggacatgctccgccacctttaccagggctgccaggtggttcagggtaacctg
gagcttacctacctgcctgccaatgccagcctctcatttctgcaggacatccaggaagtt
cagggatacatgctcatcgctcataaccaggtgaggcaagtcccactacagaggctgcgc
atcgtgagagggacccagctctttgaggacaagtatgctctggctgtactggacaaccga
gaccctttggacaatgtcaccagcaccacaggcagcaccccagaagggcttagggagctg
cagcttcgaagtctcacagagatcctgaagggaggagttttgatccgagggaaccctcag
ctctgctaccaggacactgttttgtggaaggatgtcttccgcaagagtaaccagttggct
cctgtagatatagacaccaatcgctcccgggcctgcccaccctgcgccccagcctgtaaa
gacaatcactgctggggtgagagcccccaggactgtcaaaccttgactggcaccatctgc
accagcggctgtgcccggtgcaagggccggctgcccactgactgctgccatgagcagtgt
gctgcaggctgcacaggccccaagcattccgactgcctggcctgcctccacttcaaccat
agtggcatctgtgagctgcactgcccagccctcgtcacctacaacacagacaccttcgag
tccatgcccaaccctgagggccgctacaccttcggtgccagctgtgtgaccacctgcccc
tacaactacctttctacggaagtgggatcctgcactctggtctgtcccctgaataaccaa
gaggtgactgctgaggatggaacacaacggtgtgaaaaatgcagcaagccctgtgcccga
gtgtgctatggtctgggcatggagcacctgcgaggggcaagggccatcaccagtgccaat
atccaggagtttgctggctgcaagaagatctttgggagtctggcatttttgccagagagc
tttgatggggaccctgcctctggcattgctcccctgcagcctgagcagctccaagtgttt
gaaacgctggaggagatcacaggctacctatacatttcagcatggccagacagcctccat
gacctcagtgccttccagaaccttcgagtcatccggggacgaattctccatgatggtgcc
tactcattaacgctgcaaggcctgggaatccgctggctagggctgcgctcgctgcaggag
ctgggcagcgggctggtactcattcaccgaaacacccatctctgctttgtacacactgta
ccttgggaccagctcttccggaacccccaccaggccctgctccacagtgggaaccagcca
gaggagggatgtgttcacaagggcttggcctgctacccactgtgtgcccatgggcactgc
tgggggccagggcccacccagtgtgtcaactgcagtcacttccttcggggccaagattgt
gtggaggagtgccgtgtacggaaggggctccctagggagtatgtgagtggcaagcactgt
ctgccatgccaccctgagtgtcagcctcaaaacaacacagagacctgcgttggatcggag
gctgaccagtgcaccgcctgtgcccactacaaggactcgtccttctgtgtggctcgctgc
cccagtggtgtgaaaccagacctctccttcatgcccatctggaagtacccggatgaggag
ggcatatgccagccttgccccatcaactgcacccactcctgtgtggacctggatgaacga
ggctgcccagcagagcagagagccagcccggcgacttccattatcgcaactgtggtgggc
atcctgttgttcctggtcataggggtggttgttgggatcctaatcaagagaaggcggcag
aagatccgcaagtatacaatgcgtaggctgctgcaggaaaccgagctagtggagccactg
acgcccagcggagccatgcccaaccaggcccagatgcgcatcctaaaagagactgagcta
aggaaggtgaaggtgcttggatcaggagcttttggcactgtctacaagggcatctggatc
ccagatggggagaacgtgaaaattcctgtggccatcaaggtgttgagggaaaacacatcc
cctaaagctaacaaggaaatcctagatgaagcatacgtgatggctggtgtgggctctcca
tatgtgtcccgcctcctgggcatctgcctgacatccacagtacagttggtgacacaactt
atgccctatggctgccttctggaccatgtccgagaacaccgaggtcgcctgggctcccaa
gacctcctcaactggtgtgttcagattgccaaggggatgagttacctggaggatgtacgg
ctcgtgcacagggacctggctgcccggaatgtgctggtcaagagtcccaaccacgtcaag
attacagacttcgggctggcacggctgctggacattgatgagacagagtaccatgcagat
gggggcaaggtgcccatcaaatggatggcattggaatccattcttcgacggcggttcacc
catcagagtgatgtgtggagctatggtgtgactgtgtgggagctaatgactttcggggcc
aaaccttacgatgggatcccagcccgagagatccctgacttgctggagaagggagagcgc
ttgcctcagcctccaatctgcactatcgatgtctacatgattatggtcaaatgttggatg
atagattctgaatgtcgcccgagattccgggagttggtgtcggagttctcccgtatggcg
agggatccccagcgctttgtggtcatccagaatgaggacttgggcccgtctagccccttg
gacagcaccttttaccgttccttgctggaggatgatgacatgggggacttggtagatgcc
gaagagtatctggtcccccagcagggattcttctgcccagaccctgccccaggcactgga
agcacagcccaccgtaggcaccgcagctcgtctaccaggagtggaggtggcggtgagctg
acattgggcctggaaccctcggaagaagagcctcccaggtccccactggctccctcggaa
ggggctggctctgatgtgtttgatggtgaactgggaatgggggttagcaaagggccgcag
agcatctctccacatgaccttagccctctacagcggtacagcgaggaccccacattaccc
ctgtccccggagactgatggctacgttgctcccctggcctgcagcccccagcccgaatat
gtgaaccagccagaggttcggcctcagtctcccttgaccccggaagctcctctgcctccc
gtgcggcctgctggtgctactctagaaagacccaagactctctctcctgggaagaatggg
gttgttaaagacgtttttgcctttgggggtgctgtggagaaccctgagtacttagcaccc
agaggaggcactgcctctcagccccacccttctcctgccttctgcccagcctttgacaac
ctctattactgggaccaggacccatcagaacgggggtctccaccaagtacctttgaaggg
acccctacagcagagaaccctgagtacttgggactggatgtacccgtgtga
DBGET
integrated database retrieval system
