Phodopus roborovskii (desert hamster): 127215655
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Entry
127215655 CDS
T08852
Symbol
Top2a
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
127215655 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
prob03032
]
127215655 (Top2a)
03036 Chromosome and associated proteins [BR:
prob03036
]
127215655 (Top2a)
Enzymes [BR:
prob01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
127215655 (Top2a)
DNA replication proteins [BR:
prob03032
]
Eukaryotic type
DNA Topoisomerases
127215655 (Top2a)
Chromosome and associated proteins [BR:
prob03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
127215655 (Top2a)
Centrosome formation proteins
Centriole proteins
127215655 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
127215655
NCBI-ProteinID:
XP_051032055
UniProt:
A0AAU9YLU1
LinkDB
All DBs
Position
Unknown
AA seq
1525 aa
AA seq
DB search
MELSPLQPVNENMQINKKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQM
WVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN
GKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET
ASREYKKMFKQTWMDNMGRAGDMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVR
RAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNALKVVHEQVNPRWEVCL
TMSEKGFQQISFVNSIATSKGGRHVDYVTDQIVSKLVDVVKKKNKGGVAVKAHQVKNHMW
IFVNSLIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAISCGIVESILNWVKFKAQI
QLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKY
GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD
QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKEEIAFYSLPEFEEWKSS
TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDR
KEWLTHFMEDRRQRKLLGLPEDYLYGQTTSYLTYNDFINKELILFSNSDNERSIPSMVDG
LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL
NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPPKDDHTLKFLYDDNQRVEPEWY
IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEE
LASNQYVINGEVAILNSTTIEISELPIRMWTQTYKEQVLEPMLNGTEKTPPLITDYKEYH
TDTTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILKD
FFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRG
YDSDPVKAWKEAQQKAPDEENEESDNESSDPVAESGPTFNYLLDMPLWYLTKEKKDELCK
QRNEKEQELNTLKKKSPSDLWKEDLAVFIEELEVVEAKEKQDEQVGLPGKGGKAKGKKAQ
MSEVLPSPLGKRVIPQVTMEMKAEAEKKIRKKVKSENVEGTPAEDGLEPGSLKQRIEKKQ
KREQGTMAKKQTTLPFKPVKKGKKRNPWSDSESDMSSNENNFDVPPREKDPRRAATKAKF
TMDLDSDEDFSGSDGKDEDEDFFPLDTTPPKTKVPQKNTKKALKPQKSIMSADLESDVKD
SVPASPGPPAADLPAETGQLKPSSKQTAAMKKTAAKSQSSTSTAGTKKRAVPKGTKSDLA
LSAYGPEKREPTKAKNSRKRKQSSSDDSDSDFEKEISKAAVSKKPKGENQDFQVDLDETM
APRAKSGRARKPIKYLEESDEDDLY
NT seq
4578 nt
NT seq
+upstream
nt +downstream
nt
atggagttgtcgccgctgcagcctgtaaatgaaaatatgcaaattaacaaaaagaaaaat
gaagatgccaagaaaagactatctgttgaaagaatctatcagaagaaaacacaattggaa
catatattgctccgcccagatacctacattggctctgtggaattggttacccagcaaatg
tgggtttacgatgaagatgttggcattaactatagagaagtaacttttgttcctggtttg
tataaaatctttgatgagattctagttaatgctgcagacaacaaacaaagggacccaaaa
atgtcttgtattagagtcacaattgatccagaaaataatttaattagtatatggaataat
ggaaaaggaattcctgttgttgaacacaaagttgagaaaatgtatgtcccagctctcata
tttggacagctcttaacctctagtaactatgatgatgatgaaaagaaagtaacaggtggt
cgaaatggctatggagccaagctgtgtaacatattcagtaccaaatttactgtggaaaca
gccagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggagagct
ggtgacatggaactcaagccctttaatggagaagattatacgtgtattaccttccagcct
gatttatctaagtttaagatgcagagcctggacaaagatattgttgcactgatggttaga
agggcatatgatattgctggttccactaaagatgtcaaagttttccttaatggaaataag
ctgccagtaaaagggttccgcagctatgtggatatgtatttgaaggataagttagatgaa
actgggaatgcactgaaagtagtacatgaacaagtaaacccaaggtgggaagtgtgctta
acaatgagtgaaaaaggctttcaacaaatcagctttgtcaacagcattgctacttctaag
ggtggcagacatgttgattatgtaactgatcagatcgtgagtaaacttgtcgatgtggtg
aagaagaagaacaagggtggtgttgccgtgaaagcacaccaggtgaaaaaccacatgtgg
attttcgtaaattccttgattgaaaacccaacctttgactctcagacaaaagaaaacatg
actttacaggccaagagctttggatcgacatgtcaattaagtgaaaaattcatcaaagct
gcaattagctgtggtattgtcgaaagcatactaaactgggtgaagtttaaggcccaaatc
cagttaaacaagaagtgttcagctgtgaaacataacagaatcaagggaatccccaaactt
gatgatgccaacgatgcagggagtcgaaactccactgaatgtacacttatcctgactgag
ggagactcagccaaaactctggcagtttcaggccttggtgtagttggaagagataaatat
ggggtatttcctcttagaggaaaaatactcaatgtgcgagaagcttctcataaacagatc
atggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtataagaaaaac
tatgaagatgaagattcattgaaaactcttcgttatgggaagataatgattatgacagat
caggatcaagacggttcccatatcaaaggcttgctgatcaattttatccatcacaattgg
ccctctcttctgcgacatcgttttctagaggaatttattactcccattgtaaaggtgtct
aaaaataaagaagaaatagcattctatagtcttcctgagtttgaagaatggaagagttct
actccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggcaccagcacatca
aaggaagctaaggaatattttgcagatatgaaaagacatcgtattcagttcaaatactct
ggacctgaagatgatgctgcaatcagcctggcctttagtaagaaacaggttgatgatcga
aaggaatggttgactcatttcatggaagatagacggcagcggaagttacttggccttcct
gaggattatttgtatggacaaaccacttcttacctgacctataatgacttcataaacaag
gaacttatcctgttctcaaattctgataatgaaagatctatcccatctatggttgatggt
ttgaaaccaggtcagagaaaggttttgtttacttgtttcaaacggaatgacaagcgagaa
gtgaaggttgcccagttagctggttcagtggcagaaatgtcctcttaccaccatggtgag
atgtcactgatgatgaccattatcaatttggctcagaattttgtgggtagtaataatttg
aaccttttacaacccattggtcagtttggtaccaggctgcatggtggcaaggattcagct
agtcctcgatacatctttactatgctcagccctttgactcggttgttatttccaccaaaa
gatgatcacacattaaagtttttatatgatgacaaccagcgtgttgagcctgaatggtac
attcctattattcccatggtactgataaatggcgctgagggaattggtactgggtggtcc
tgcaaaatccccaactttgatgtccgtgaagtcgtaaataatatccgacgactattggat
ggagaagaacctctgcccatgctcccaagttacaagaatttcaaaggtactattgaagaa
ctggcttcaaatcagtatgtgattaatggagaagtagctattctgaattccacgaccatt
gaaatctcagagcttcccatcagaatgtggacccagacttacaaagaacaggttctagaa
cccatgttgaatggcactgagaagacaccccctcttataacagactataaggaataccac
acagacaccactgtcaagtttgtcataaagatgactgaagaaaaattagcagaggcagag
agagtgggactacacaaagtcttcaaactgcagactagtctcacttgcaactctatggtg
ctttttgaccatgtaggttgcttaaagaaatatgacaccgtgttggatattctgaaagac
ttctttgagctcaggcttaaatattatggattaagaaaagaatggcttctaggaatgctt
ggtgcagaatctgctaaactgaataatcaagctcgttttatattagagaaaatagatggc
aaaataatcattgaaaataaacctaaaaaagagctaattaaagttctaattcagagagga
tatgattccgatcctgtgaaagcctggaaagaagctcagcaaaaggctccagatgaagaa
aatgaagaaagtgacaatgaaagcagtgaccccgtagcagagtctggaccaacttttaat
taccttcttgatatgcccctttggtacctaaccaaggaaaagaaagatgaactgtgcaaa
cagagaaatgaaaaggaacaagagctcaacacattaaagaagaagagtccatcagatttg
tggaaggaagatctagctgtttttattgaagaactggaggttgttgaagccaaggaaaaa
caagacgaacaagtaggacttcctggaaaaggagggaaagcaaaagggaagaaagcacaa
atgtctgaagtcttgccttctcctctgggaaaaagagttattccccaagtgaccatggag
atgaaagcagaagcagagaagaaaattaggaaaaaagttaagagtgaaaacgttgagggc
acgcctgctgaggatggtctggaaccaggaagcctaaaacaaagaatagagaagaagcag
aagagagagcaaggtaccatggcaaagaagcagactacattgccttttaagcccgtcaaa
aaggggaaaaagagaaacccctggtctgattctgaatcggatatgagtagtaacgaaaat
aattttgatgtccctccacgagaaaaggatccgcgaagagctgcaacaaaagccaaattc
acgatggatttggattcagatgaagatttctcaggttctgatggaaaggacgaagatgaa
gattttttcccattagatactactccacctaagaccaaagttccccaaaaaaatactaaa
aaagcactgaagccacagaagagtatcatgtctgctgaccttgaaagtgatgtgaaggac
agtgtgccagcttctccaggccctcctgctgctgacttgccagctgaaactggacagtta
aaaccatcttccaaacagactgcagcaatgaagaagacagcagccaaaagccagtcttca
acatccactgctggtaccaaaaagagagctgtaccaaagggaaccaaatcagatttagcc
ttgagtgcttatggccctgaaaagcgtgagcctaccaaagccaagaacagccgcaaaagg
aagcagtcctcttctgatgattccgactctgattttgagaaagaaatttccaaagctgct
gtgagcaagaaacccaagggagagaatcaggatttccaagtggacttagatgaaactatg
gctcctcgagcaaaatctggacgagcaaggaagcctattaaatacctggaggagtcagat
gaggatgatctctactga
DBGET
integrated database retrieval system
