Phodopus roborovskii (desert hamster): 127216013 Help Entry 127216013         CDS       T08852                                  Symbol Nos1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism prob  Phodopus roborovskii (desert hamster) Pathway prob00220   Arginine biosynthesis prob00330   Arginine and proline metabolism prob01100   Metabolic pathways prob04020   Calcium signaling pathway prob04081   Hormone signaling prob04145   Phagosome prob04371   Apelin signaling pathway prob04713   Circadian entrainment prob04730   Long-term depression prob04926   Relaxin signaling pathway prob04970   Salivary secretion prob05010   Alzheimer disease prob05014   Amyotrophic lateral sclerosis prob05022   Pathways of neurodegeneration - multiple diseases prob05410   Hypertrophic cardiomyopathy prob05412   Arrhythmogenic right ventricular cardiomyopathy prob05414   Dilated cardiomyopathy prob05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:prob00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     127216013 (Nos1)    00330 Arginine and proline metabolism     127216013 (Nos1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     127216013 (Nos1)    04020 Calcium signaling pathway     127216013 (Nos1)   09133 Signaling molecules and interaction    04081 Hormone signaling     127216013 (Nos1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     127216013 (Nos1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     127216013 (Nos1)   09154 Digestive system    04970 Salivary secretion     127216013 (Nos1)   09156 Nervous system    04730 Long-term depression     127216013 (Nos1)   09159 Environmental adaptation    04713 Circadian entrainment     127216013 (Nos1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     127216013 (Nos1)    05014 Amyotrophic lateral sclerosis     127216013 (Nos1)    05022 Pathways of neurodegeneration - multiple diseases     127216013 (Nos1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     127216013 (Nos1)    05412 Arrhythmogenic right ventricular cardiomyopathy     127216013 (Nos1)    05414 Dilated cardiomyopathy     127216013 (Nos1)    05416 Viral myocarditis     127216013 (Nos1) Enzymes [BR:prob01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      127216013 (Nos1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  127216013 NCBI-ProteinID:  XP_051032485 UniProt:  A0AAU9YVJ6 LinkDB All DBs Position Unknown AA seq 1463 aa AA seqDB search MEEHTFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTQPLGPPTKAVDLSHQTSASKDQPLAAGRVTGPGNGPQHAQGNGQGAGSVSQANGLAI DPTMKSIKANLQDSGDHDELLKEIEPVLSLLNSGGKMVSRGGPAKAEMKDTGVQVDREPD CKLHKALPLGSENDRVFNDLWGKGNVPVVLNNPYSEKEQPPASGKQSPTKNGSPSRGPRF LKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSVMLPSQHTRKPEDVRTKDQLFPLAKE FLDQYYSSIKRFGSKAHMDRLEEVNREIESTSTYQLKDTELIYGAKHAWRNASRCVGRIQ WSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLI RYAGYKQPDGSTLGDPANVQFTEICIQQGWKAPRGRFDILPLLLQANGNDPELFQIPPEL VLEVPIRHPKFDWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCD NSRYNILEEVAKKMDLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIK HMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTN GTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHA FDAKAMSMEEYDIVHLEHEALVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKY PEPLRFFPRKGPSLSRADSEAHSLVAVRDSQRRSYKVRFNSVSSYSDSRKSSGDGPDLRD NFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEA FRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELTQGLSN VHKKRVSAARFLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNHEDLVNA LIERLEDAPPANHMVKVEMLEERNTALGVISNWKDESRLPPCTIFQAFKYYLDITTPPTP LQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTMVEVLEEFPSIQMPATLLLTQ LSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPIHHGVCSSWLNRIQADDVVPC FVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVFGCRQS KIDHIYREETLQAKNKGVFRELYTAYSREPDRPKKYVQDVLQEQLAEPVYRALKEQGGHV YVCGDVTMAADVLKAIQRIMTQQGKLSEEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTN RLRSESIAFIEESKKDTDEVFSS NT seq 4392 nt NT seq  +upstreamnt  +downstreamnt atggaagagcacacatttggggttcagcagatccagcccaatgtcatttccgtccgtctc ttcaaacgcaaagtcggaggtctgggcttcctggtgaaggaacgggtcagcaagccacct gtaatcatctcagatctgattcggggaggtgccgcggagcagagcggtcttatccaagct ggagacatcattctcgccgtcaatggccgacccctggtggacctcagctatgacagcgcc ctggaggtgctcaggggcattgcctctgagacccatgtggtcctcattctgagaggccct gagggcttcactacacacctagaaaccaccttcacaggggatggaacccccaagaccatt cgggtgacccagcccctgggtccccccacaaaagccgtcgatctgtcccaccaaacatca gccagcaaagaccagccattagcagcaggccgggtcacaggtcctggcaatggacctcag catgcccaaggcaatggacagggagctggctcagtctcccaggctaatggtctggccatt gaccctacaatgaaaagtatcaaggccaatctccaggacagtggggatcatgacgaactg ctcaaagagatagaacctgtgctcagcctcctcaacagcgggggcaaaatggtcagcaga gggggtccagccaaagcagagatgaaggacacaggagtccaggtggacagagaaccggac tgcaagctgcacaaagctctgcccctgggcagtgagaatgaccgagtcttcaatgacctg tgggggaagggcaacgtccccgtggtcctcaacaacccatattcagagaaggagcagccg cctgcctcggggaaacagtcccctaccaagaacggcagcccttccaggggcccccggttc ctcaaggtcaagaactgggagacagacgtggtcctcactgacacactgcatcttaagagt acattggaaacggggtgcacagagcacatctgcatgggctctgtcatgctgccatcccaa cacactcggaagccagaagatgtccgcacaaaggaccagctcttcccactagccaaagaa tttcttgaccaatactactcatccatcaaaaggtttggctccaaggcccacatggacagg ctggaggaagtgaacagggaaatcgaaagcaccagcacctaccagctcaaggatacggag ctcatctatggtgccaagcatgcctggcggaatgcctctcgatgcgtgggcaggatccag tggtccaagctgcaggtgtttgatgccagagactgtaccacagcgcacggcatgttcaac tacatctgcaaccacgtcaagtatgccaccaacaaagggaacctcaggtcggccatcact atattccctcagaggactgacggcaagcatgacttccgagtgtggaactcacagctcatc cgctatgccggctacaagcaaccagatggctctactttgggggaccctgcgaacgtgcaa tttacagagatctgtatacagcagggctggaaagcaccacgaggccggttcgacatcctg ccgctcctgctccaggccaatggcaatgaccctgagctcttccagatccccccagagctg gtgctggaagtgcccatcagacaccccaagtttgactggtttaaagacctgggactcaaa tggtatggcctccctgctgtgtccaacatgctgctggagattgggggcctggagttcagc gcctgcccctttagtggctggtacatgggcacagagatcggtgtccgtgactactgtgac aactctcgatacaacatcctggaggaagtggccaagaagatggacttggacatgaggaag acatcctccctgtggaaggaccaggcactggtggagatcaacattgccgtgctctatagc ttccagagtgacaaggtgaccatcgttgaccaccactctgccaccgagtccttcatcaaa cacatggaaaatgaataccgctgcagagggggctgccccgcagactgggtgtggattgtg ccccccatgtcgggcagcatcacccctgtcttccaccaggagatgctcaactatcgactc accccgtccttcgaataccagcctgacccatggaacacccatgtgtggaagggaactaat gggacccccacgaagcggagagcgattggcttcaagaaattggcagaagctgtcaagttc tcagccaagctgatggggcaggccatggccaagagggtcaaagcaaccattctctatgcc acggagacaggcaaatctcaagcctatgccaagaccctgtgtgagatcttcaagcacgcc tttgatgccaaggcaatgtccatggaggagtacgacattgtgcacctggagcacgaagcc ctggtcttggtggtcaccagcacctttggcaatggagacccccctgagaatggggagaaa ttcggctgtgctctgatggagatgaggcaccccaactctgtgcaggaggaaaggaagtac ccggaacccttgcgtttctttccccgaaaagggccttccctatcccgtgctgactctgaa gcccacagtctggttgctgtgcgtgacagccagcgcaggagctacaaggtccgattcaac agcgtctcctcctattctgactcccgcaagtcgtcaggcgatggacccgacctcagggac aactttgagagtactgggccactggccaacgtgaggttctctgtattcggcctgggctct cgggcataccctcacttctgcgccttcgggcacgcagtggacaccctcctggaggagctg ggaggggagaggattctgaagatgagggagggagatgagctctgcgggcaggaagaggct ttcaggacctgggccaagaaggtcttcaaggcagcctgtgatgtgttctgtgtgggggat gatgtcaacattgagaaggcaaacaattccctcatcagcaatgaccgcagctggaagagg aacaaattccgcctcacctacgtggccgaagctccagaactaacacaaggtctttccaat gtccacaaaaagcgagtctcagccgcccgattccttagccgccaaaacctgcagagccct aaatccagccgatcaaccatcttcgtgcgtctccacaccaatgggaatcaggagctgcag taccagccaggggaccacctgggtgtcttccctggcaaccacgaggacctcgtgaacgca ctcattgagcggctggaggatgcaccgcctgccaaccacatggtgaaggtggagatgctg gaggagaggaacacggccctgggtgtcatcagtaactggaaggatgaatctcgcctccca ccctgcaccatcttccaggccttcaagtactacctagacatcaccacgccgcccacaccc ctgcagctgcaacagttcgcctccctggccaccagtgagaaggagaagcagcggctgctg gtcctcagcaaggggcttcaggaatacgaagagtggaaatggggcaagaaccccactatg gtggaggtgctggaggagttcccgtccatccagatgccagccacgctgctcctcacccag ctgtccctgctgcagcctcgttactattccatcagctcctcgccggacatgtacccggat gaggtgcacctcaccgtggccattgtctcctaccacacccgagatggggaaggaccaatc caccacggcgtgtgctcctcctggctcaaccggatacaggctgatgatgtagtcccctgc ttcgtgagaggcgcccctagcttccacctgcctcgaaacccccaggttccttgcatcctg gttggcccaggcaccggcattgcacccttccgaagcttctggcaacagcgacagtttgac atccaacacaaaggaatgaatccctgccctatggtcctggtcttcgggtgtcgacaatcc aagatagatcacatctacagagaggagaccctgcaggccaagaacaagggtgtcttcaga gagctgtatactgcctattcccgggaacctgacaggccaaagaaatacgtacaggatgtg ctgcaggagcaactggccgagcctgtgtaccgtgccctgaaggagcaaggaggccacgtt tacgtctgtggggacgtcaccatggccgccgatgtcctcaaagccatccagcgcataatg acccaacaggggaagctctcagaggaagatgctggtgtgttcatcagcaggctgagggat gacaatcgctaccatgaggacatctttggagtcaccctgcgaacatatgaagtgaccaac cgccttagatctgagtccattgccttcattgaagagagcaaaaaagacacggatgaggtt ttcagctcctaa

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