Phodopus roborovskii (desert hamster): 127216594
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Entry
127216594 CDS
T08852
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob00310
Lysine degradation
prob01100
Metabolic pathways
prob05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
127216594 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
127216594 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
prob03036
]
127216594 (Dot1l)
Enzymes [BR:
prob01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
127216594 (Dot1l)
Chromosome and associated proteins [BR:
prob03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
127216594 (Dot1l)
HMT complexes
Dot1-containing complex
127216594 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
VPS13_M
Motif
Other DBs
NCBI-GeneID:
127216594
NCBI-ProteinID:
XP_051033290
LinkDB
All DBs
Position
Unknown
AA seq
1733 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVS
ENKAAATEAPVDSGAEEEKSGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAAN
AERKSKKSQSALDLLRSSPAAPPSASPQDAYRAPHSPFYQLPPSTQLHSPNPLLVAPTPP
ALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFGHCQAQKEE
IRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLQLLRA
RCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLKSC
VPPDDALSLHLRGKATLGRELEADAGRLRLELDCAKISLPHLSSMSPELSMNGHVTGYEL
CNAASRSSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLR
RHLSQDHTGAGKAAASESHPRAEHAKESTLPYQSPGFSNSMKLSPQDPLPSSPASSPLTS
EKGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS
PVPQPREASSTLEKQIGASTHGAGGNAAGSRSLALAPTGFYAGSVAISGALANSPAPLAS
GMESTVFDESSGPSSLFAIMGSRSTPPQHPPLLPQPRNSGPASPAHQLSASPRLSVTTQG
PLLDTSKGELPSDPAFSDPESEAKRRIVFSIAASSSSKQSPSTRHSPLTSSTRGDCVQSH
GQDSRKRSRRKRASAGNPSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLE
ITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSAR
IERKIATISLESKSPPKTLENGGGLVGRKSAPSSEPMNSSKWKSTFSPISDLSLAKAVDS
PLQAGSALSHSPLFSFRPALEEPAAETKLPTHSRKSFAGSLAAAEGPSPGANPPNGLAFS
GGLAADLGLHSFNDGASLSHKGPEVASLSASVSFPSQRGKDNTTEANPFLSRRQPEGLKG
EGSASKESSEALPLCGPADKVALPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGLLGA
PGLVTVASSAGSVTPAAQAPRPFLSTFTPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTV
PAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFTHAVPSASAHPFGAGVSSGAVC
SSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPPPPN
VALPPPPALLASNSEPVLLQSLASLPANKAFLPPSSAASLQPANASLSVKLASLPHKVSR
PSFTVHHQPLPRLALAQAAPAAPQASSSGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5202 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgccagtgggcgccgagcccgccgtctac
ccgtggccgctgcctgtctacgacaagcaccacgatgctgctcatgaaattattgagact
atccggtgggtctgtgaggaaatcccggatctcaagctggcgatggagaactatgtcctg
atcgactatgacaccaaaagctttgaaagcatgcagagactgtgtgacaagtacaaccga
gccatcgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaatact
cgaccatccaatgggctcctgcggcacatcctgcagcaggtgtacaaccactctgtgact
gaccctgagaagctcaacaactacgagcccttttcccctgaggtgtacggggagacctcc
tttgacctggtcgcccagatgattgacgagatcaagatgaccgaggatgacctgtttgta
gacctgggcagtggtgtggggcaggttgtccttcaggttgctgctgccaccaactgcaaa
catcactacggagtggagaaagcagacatcccagccaagtacgcggagaccatggatcga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcagaggagtggagggagcggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggcggcagaatcgtctcctcaaagccctttgcccctctgaacttcaggatcaat
agcaggaacttgagtgacattggcaccatcatgcgtgtggtagagctgtcgcccctgaag
ggctctgtgtcatggactgggaagcctgtctcctactacctgcacactattgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggagcaggaggca
gctcggcgcaggcaacagcgagagaacaagagcaatgcaaccacccccaccaaggtctca
gagaacaaggcagctgccactgaggcaccggtggactctggtgctgaggaagaaaagtca
ggtgtggccactgtcaaaaagccatctccctctaaagcccggaagaagaagctgaacaag
aaagggaggaagatggctggccggaagcgtgggcggcccaagaaaatgagtgctgcaaac
gcagagcgcaagtccaagaagagccaaagtgcactggacctcctgcgctcctctcctgca
gccccaccctcagcttcaccccaggatgcgtacagggcaccacatagcccgttctaccag
ctacctccgagcacgcagctccactcccccaatccactgctggtggcacccaccccacct
gcattacagaagcttttagagtccttcaaaatccagtacctgcagttcctggcttacaca
aaaaccccacagtacaaggccaacctgcagcagcttctggaccaggagaaggagaagaac
acacagctgctgggcactgcacagcagctcttcggtcattgtcaggcccaaaaggaggag
atccgaagactgttccagcagaagctggatgagttgggcgtgaaggctctgacctacaat
gacctgattcaggcccagaaggagatctctgcccacaaccagcagctgcgggagcagtcg
gagcagctggagaaggacaacagcgagctgcggagccagagcctacaactgctcagggcc
cgatgtgaggagctgaggctggactggtccacgttgtctctggagaacctgcgcaaagag
aagcaggccctgcggagccagatctcagagaagcagcgacactgcctggagctgcagatc
agcattgtggagctggagaagagccaacgacagcaggagctcctgcagttgaagtcctgt
gtgccaccagacgatgctctgtccctgcacctgcgtggcaaggctaccctgggccgagag
ctggaggctgatgctgggcggttgcgtcttgagctggactgtgccaagatctccctgccg
cacctcagcagcatgagtcctgagctctccatgaatggccatgtcacaggctacgagctc
tgcaatgcagctagtcggtcctcgtccaagcagaacactccccagtaccttgcctccccc
ttggaccaggaggtagtaccctgcacccccagccacagtggccgacctcggctagaaaag
ttgtctggcctggctttgccggactacacccggttgtcaccagccaagattgtgttgagg
cggcacctgagccaggaccacaccggggctggcaaagcagctgccagtgagtcacaccct
cgggcagagcatgccaaggagagcacccttccctaccagagccctggtttctccaacagc
atgaagctcagcccccaagatcctctgccttcctccccggcgtcctcgccactcacctca
gagaagggcagtgagaagggtgtgaaggagcgtgcctacagtagccacggggagactatc
accagcctgcccgtcagcattccactcagcactgtgcagcccaacaagctgcctgtcagc
atcccactggccagtgtggtgctgcccagccgcgccgagagggcaaggagcacgcccagc
cctgtgccacagccccgagaggcctcatccacacttgaaaagcagatcggtgcttctacc
catggtgcagggggcaatgcagcagggagcaggagtcttgccttggcacccacaggcttc
tatgctggttcggtggcaatcagtggggccctggccaacagcccagcacctctggcctct
ggaatggaatcaactgtttttgacgagtcctctggccctagcagcctctttgccatcatg
gggtctcgcagcacaccaccacagcacccacctctgctgccgcagccccgcaactctggc
cctgcctctcctgcacaccaactctcagccagtccccgtctgagtgtgaccacccagggt
ccactgctggacaccagcaaaggggagctgccttctgatcctgccttctcagacccggag
agtgaagctaagaggagaatcgtgttcagcatcgcagccagttccagctcgaagcagtcg
ccttccactaggcacagccccttgacctccagcacccgtggggactgtgtacagagccat
gggcaggacagtcgtaagcgcagcagaaggaagcgtgcgtcagctggaaaccccagcctc
agcacaggtgtgtcccccaagcgccgggctctgccaactgttgctggcctcttcacgcag
tcttcggggtctcccctcaacctcaactccatggtcagcaacatcaatcagcccctggag
atcacagccatctcgtcccctgagagctccctgaagagttcccccaccccctaccaggac
cacgatcagcccccagtgcttaggaaggagcggcctctgggcccaaccaatggggcccat
tactcaccactgacctcagatgaggagccaggctctgaagatgagcccagtagtgcccga
attgagagaaaaattgcaacaatctccttagaaagcaaatctcccccgaagacgctggaa
aatggtggtggcctggtgggaaggaagtctgccccctcaagtgagcctatgaatagcagc
aaatggaagtccaccttctcacctatctctgacctcagcttggccaaggccgtggacagt
ccgctacaggctggctctgcgctgagccacagccccctgttctctttccggccagctctg
gaggagcctgctgctgagaccaagctccccacccactcaagaaagagttttgctggctct
ctggctgcagctgagggcccgagccctggcgccaatcctcccaatggcctggccttcagt
gggggcctcgccgcagaccttggtttacacagcttcaacgatggtgcttccctctcccat
aagggccctgaagtggccagcttgagcgcctccgtgagcttcccatcccagcggggcaag
gacaataccacagaagccaaccccttcctcagcaggcggcagccggagggtctgaagggt
gagggcagtgccagcaaggagtccagcgaggccctacccctgtgtgggcctgcagacaag
gttgcattgcctcatggcagcagggccagcaagggccgtgaccgggagctggacttcaag
ggcggccacaacctcttcatctctgctgcagctgtgcctccaggtggcctccttggtgcc
cctggcctcgtaactgtggcttcctctgcgggcagtgtgacacctgctgcccaggctccc
cggcccttcctgagcaccttcaccccgggtccccagtttactctgggccccatgtccctg
caggccaacctgggctctgtggctggctcatccgtgctgcagtccttgttcagtactgtg
ccagctgctgcaggcttggtgcatgtatcatccactgcgacccgactcaccaactctcac
accatgggcagcttctcctctggggtggccggcggaaccgttggaggtgtctttacccat
gcggtgccttctgcctctgctcacccgtttggagctggtgtcagcagcggggctgtgtgt
agcagtgccacactgggcctgagcccgctgcaggcggcggctagcacctcggcttcttcc
tttcaggctgcggcttcagtcgagactaggccgccccctccacctcccctgcttcctcct
cagcacctgggccggccccctgcggggccacctgtcctccatgcaccccctcctcctaac
gtcgccttgcctcctccacctgcgctgctggcttctaactcagagccagtgcttctgcag
agcctggcctccctcccggctaacaaagctttcttacccccctcctctgccgcctctctg
cagcctgctaacgcctctctgtctgtcaagctcgcctccctcccacacaaggtctcccgc
ccctccttcacggtgcaccaccagcccctgccccggctggccctggcgcaggccgcgccc
gccgccccgcaggccagctcctcggggccatctgctgtgtgggtttcccttggcatgccg
cctccttatgccgcgcacctttcgggggttaagcctcgataa
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integrated database retrieval system
