Phodopus roborovskii (desert hamster): 127216731
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Entry
127216731 CDS
T08852
Name
(RefSeq) mitogen-activated protein kinase 1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob01521
EGFR tyrosine kinase inhibitor resistance
prob01522
Endocrine resistance
prob01524
Platinum drug resistance
prob04010
MAPK signaling pathway
prob04012
ErbB signaling pathway
prob04014
Ras signaling pathway
prob04015
Rap1 signaling pathway
prob04022
cGMP-PKG signaling pathway
prob04024
cAMP signaling pathway
prob04062
Chemokine signaling pathway
prob04066
HIF-1 signaling pathway
prob04068
FoxO signaling pathway
prob04071
Sphingolipid signaling pathway
prob04072
Phospholipase D signaling pathway
prob04114
Oocyte meiosis
prob04140
Autophagy - animal
prob04148
Efferocytosis
prob04150
mTOR signaling pathway
prob04151
PI3K-Akt signaling pathway
prob04210
Apoptosis
prob04218
Cellular senescence
prob04261
Adrenergic signaling in cardiomyocytes
prob04270
Vascular smooth muscle contraction
prob04350
TGF-beta signaling pathway
prob04360
Axon guidance
prob04370
VEGF signaling pathway
prob04371
Apelin signaling pathway
prob04380
Osteoclast differentiation
prob04510
Focal adhesion
prob04520
Adherens junction
prob04540
Gap junction
prob04550
Signaling pathways regulating pluripotency of stem cells
prob04611
Platelet activation
prob04613
Neutrophil extracellular trap formation
prob04620
Toll-like receptor signaling pathway
prob04621
NOD-like receptor signaling pathway
prob04625
C-type lectin receptor signaling pathway
prob04650
Natural killer cell mediated cytotoxicity
prob04657
IL-17 signaling pathway
prob04658
Th1 and Th2 cell differentiation
prob04659
Th17 cell differentiation
prob04660
T cell receptor signaling pathway
prob04662
B cell receptor signaling pathway
prob04664
Fc epsilon RI signaling pathway
prob04666
Fc gamma R-mediated phagocytosis
prob04668
TNF signaling pathway
prob04713
Circadian entrainment
prob04720
Long-term potentiation
prob04722
Neurotrophin signaling pathway
prob04723
Retrograde endocannabinoid signaling
prob04724
Glutamatergic synapse
prob04725
Cholinergic synapse
prob04726
Serotonergic synapse
prob04730
Long-term depression
prob04810
Regulation of actin cytoskeleton
prob04910
Insulin signaling pathway
prob04912
GnRH signaling pathway
prob04914
Progesterone-mediated oocyte maturation
prob04915
Estrogen signaling pathway
prob04916
Melanogenesis
prob04917
Prolactin signaling pathway
prob04919
Thyroid hormone signaling pathway
prob04921
Oxytocin signaling pathway
prob04926
Relaxin signaling pathway
prob04928
Parathyroid hormone synthesis, secretion and action
prob04929
GnRH secretion
prob04930
Type II diabetes mellitus
prob04933
AGE-RAGE signaling pathway in diabetic complications
prob04934
Cushing syndrome
prob04935
Growth hormone synthesis, secretion and action
prob04960
Aldosterone-regulated sodium reabsorption
prob05010
Alzheimer disease
prob05020
Prion disease
prob05022
Pathways of neurodegeneration - multiple diseases
prob05034
Alcoholism
prob05132
Salmonella infection
prob05133
Pertussis
prob05135
Yersinia infection
prob05140
Leishmaniasis
prob05142
Chagas disease
prob05145
Toxoplasmosis
prob05152
Tuberculosis
prob05160
Hepatitis C
prob05161
Hepatitis B
prob05163
Human cytomegalovirus infection
prob05164
Influenza A
prob05165
Human papillomavirus infection
prob05166
Human T-cell leukemia virus 1 infection
prob05167
Kaposi sarcoma-associated herpesvirus infection
prob05170
Human immunodeficiency virus 1 infection
prob05171
Coronavirus disease - COVID-19
prob05200
Pathways in cancer
prob05203
Viral carcinogenesis
prob05205
Proteoglycans in cancer
prob05206
MicroRNAs in cancer
prob05207
Chemical carcinogenesis - receptor activation
prob05208
Chemical carcinogenesis - reactive oxygen species
prob05210
Colorectal cancer
prob05211
Renal cell carcinoma
prob05212
Pancreatic cancer
prob05213
Endometrial cancer
prob05214
Glioma
prob05215
Prostate cancer
prob05216
Thyroid cancer
prob05218
Melanoma
prob05219
Bladder cancer
prob05220
Chronic myeloid leukemia
prob05221
Acute myeloid leukemia
prob05223
Non-small cell lung cancer
prob05224
Breast cancer
prob05225
Hepatocellular carcinoma
prob05226
Gastric cancer
prob05230
Central carbon metabolism in cancer
prob05231
Choline metabolism in cancer
prob05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
prob05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
127216731
04012 ErbB signaling pathway
127216731
04014 Ras signaling pathway
127216731
04015 Rap1 signaling pathway
127216731
04350 TGF-beta signaling pathway
127216731
04370 VEGF signaling pathway
127216731
04371 Apelin signaling pathway
127216731
04668 TNF signaling pathway
127216731
04066 HIF-1 signaling pathway
127216731
04068 FoxO signaling pathway
127216731
04072 Phospholipase D signaling pathway
127216731
04071 Sphingolipid signaling pathway
127216731
04024 cAMP signaling pathway
127216731
04022 cGMP-PKG signaling pathway
127216731
04151 PI3K-Akt signaling pathway
127216731
04150 mTOR signaling pathway
127216731
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
127216731
04148 Efferocytosis
127216731
09143 Cell growth and death
04114 Oocyte meiosis
127216731
04210 Apoptosis
127216731
04218 Cellular senescence
127216731
09144 Cellular community - eukaryotes
04510 Focal adhesion
127216731
04520 Adherens junction
127216731
04540 Gap junction
127216731
04550 Signaling pathways regulating pluripotency of stem cells
127216731
09142 Cell motility
04810 Regulation of actin cytoskeleton
127216731
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
127216731
04613 Neutrophil extracellular trap formation
127216731
04620 Toll-like receptor signaling pathway
127216731
04621 NOD-like receptor signaling pathway
127216731
04625 C-type lectin receptor signaling pathway
127216731
04650 Natural killer cell mediated cytotoxicity
127216731
04660 T cell receptor signaling pathway
127216731
04658 Th1 and Th2 cell differentiation
127216731
04659 Th17 cell differentiation
127216731
04657 IL-17 signaling pathway
127216731
04662 B cell receptor signaling pathway
127216731
04664 Fc epsilon RI signaling pathway
127216731
04666 Fc gamma R-mediated phagocytosis
127216731
04062 Chemokine signaling pathway
127216731
09152 Endocrine system
04910 Insulin signaling pathway
127216731
04929 GnRH secretion
127216731
04912 GnRH signaling pathway
127216731
04915 Estrogen signaling pathway
127216731
04914 Progesterone-mediated oocyte maturation
127216731
04917 Prolactin signaling pathway
127216731
04921 Oxytocin signaling pathway
127216731
04926 Relaxin signaling pathway
127216731
04935 Growth hormone synthesis, secretion and action
127216731
04919 Thyroid hormone signaling pathway
127216731
04928 Parathyroid hormone synthesis, secretion and action
127216731
04916 Melanogenesis
127216731
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
127216731
04270 Vascular smooth muscle contraction
127216731
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
127216731
09156 Nervous system
04724 Glutamatergic synapse
127216731
04725 Cholinergic synapse
127216731
04726 Serotonergic synapse
127216731
04720 Long-term potentiation
127216731
04730 Long-term depression
127216731
04723 Retrograde endocannabinoid signaling
127216731
04722 Neurotrophin signaling pathway
127216731
09158 Development and regeneration
04360 Axon guidance
127216731
04380 Osteoclast differentiation
127216731
09159 Environmental adaptation
04713 Circadian entrainment
127216731
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
127216731
05206 MicroRNAs in cancer
127216731
05205 Proteoglycans in cancer
127216731
05207 Chemical carcinogenesis - receptor activation
127216731
05208 Chemical carcinogenesis - reactive oxygen species
127216731
05203 Viral carcinogenesis
127216731
05230 Central carbon metabolism in cancer
127216731
05231 Choline metabolism in cancer
127216731
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
127216731
09162 Cancer: specific types
05210 Colorectal cancer
127216731
05212 Pancreatic cancer
127216731
05225 Hepatocellular carcinoma
127216731
05226 Gastric cancer
127216731
05214 Glioma
127216731
05216 Thyroid cancer
127216731
05221 Acute myeloid leukemia
127216731
05220 Chronic myeloid leukemia
127216731
05218 Melanoma
127216731
05211 Renal cell carcinoma
127216731
05219 Bladder cancer
127216731
05215 Prostate cancer
127216731
05213 Endometrial cancer
127216731
05224 Breast cancer
127216731
05223 Non-small cell lung cancer
127216731
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
127216731
05170 Human immunodeficiency virus 1 infection
127216731
05161 Hepatitis B
127216731
05160 Hepatitis C
127216731
05171 Coronavirus disease - COVID-19
127216731
05164 Influenza A
127216731
05163 Human cytomegalovirus infection
127216731
05167 Kaposi sarcoma-associated herpesvirus infection
127216731
05165 Human papillomavirus infection
127216731
09171 Infectious disease: bacterial
05132 Salmonella infection
127216731
05135 Yersinia infection
127216731
05133 Pertussis
127216731
05152 Tuberculosis
127216731
09174 Infectious disease: parasitic
05145 Toxoplasmosis
127216731
05140 Leishmaniasis
127216731
05142 Chagas disease
127216731
09164 Neurodegenerative disease
05010 Alzheimer disease
127216731
05020 Prion disease
127216731
05022 Pathways of neurodegeneration - multiple diseases
127216731
09165 Substance dependence
05034 Alcoholism
127216731
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
127216731
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
127216731
04933 AGE-RAGE signaling pathway in diabetic complications
127216731
04934 Cushing syndrome
127216731
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
127216731
01524 Platinum drug resistance
127216731
01522 Endocrine resistance
127216731
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
prob01001
]
127216731
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
prob03036
]
127216731
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
prob04147
]
127216731
Enzymes [BR:
prob01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
127216731
Protein kinases [BR:
prob01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
127216731
Chromosome and associated proteins [BR:
prob03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
127216731
Exosome [BR:
prob04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
127216731
BRITE hierarchy
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Haspin_kinase
Choline_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
127216731
NCBI-ProteinID:
XP_051033508
LinkDB
All DBs
Position
Unknown
AA seq
358 aa
AA seq
DB search
MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQ
TYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLS
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG
FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG
ILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRI
EVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq
1077 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggcggcgggcccggagatggtccgcgggcaggtgttcgacgtgggg
ccgcgctacaccaacctctcctacatcggagagggcgcctacggcatggtttgctcagct
tacgataatctcaacaaagttcgagttgctatcaagaaaatcagcccttttgagcaccag
acctactgccagagaaccctaagagagataaaaatcttgctgcgtttcagacatgagaat
atcatcggcatcaatgacatcatccgggcaccaaccattgagcaaatgaaagatgtatat
atagtacaggacctcatggagacagatctttacaagctcttgaagacacaacacctcagc
aatgaccatatctgctattttctgtatcagatcctgagaggattaaaatacatccattca
gctaatgttctgcatcgtgacctcaagccttccaacctcctgctgaacaccacttgtgat
ctcaagatctgtgactttggccttgcccgtgttgcagatccggatcatgatcacacaggg
ttcttgacagagtatgtagccacacgttggtacagagctccagaaattatgttgaattcc
aagggttataccaagtccattgacatctggtctgtgggctgcatcctggcagagatgctc
tccaacaggcctatcttccccgggaagcactaccttgaccagttgaatcacatcctgggt
attcttggatctccatcacaggaagatctgaattgtataataaatttaaaagctagaaac
tacttgctttctctcccgcacaaaaataaggtgccatggaacaggctgttcccaaatgct
gactctaaagctctggacttactggataaaatgttgacatttaaccctcacaaaaggatt
gaagttgaacaggctctggcccacccatacctggagcagtattatgacccaagtgatgag
cccattgccgaagcaccattcaagtttgacatggaattggatgacttacctaaggagaag
ctcaaagaactcatttttgaagagactgctagattccagccaggatacagatcttaa
DBGET
integrated database retrieval system