Phodopus roborovskii (desert hamster): 127217013 Help Entry 127217013         CDS       T08852                                  Symbol Sos1 Name (RefSeq) son of sevenless homolog 1   KO K03099   son of sevenless Organism prob  Phodopus roborovskii (desert hamster) Pathway prob01521   EGFR tyrosine kinase inhibitor resistance prob01522   Endocrine resistance prob04010   MAPK signaling pathway prob04012   ErbB signaling pathway prob04014   Ras signaling pathway prob04062   Chemokine signaling pathway prob04068   FoxO signaling pathway prob04072   Phospholipase D signaling pathway prob04150   mTOR signaling pathway prob04151   PI3K-Akt signaling pathway prob04510   Focal adhesion prob04540   Gap junction prob04630   JAK-STAT signaling pathway prob04650   Natural killer cell mediated cytotoxicity prob04660   T cell receptor signaling pathway prob04662   B cell receptor signaling pathway prob04664   Fc epsilon RI signaling pathway prob04714   Thermogenesis prob04722   Neurotrophin signaling pathway prob04810   Regulation of actin cytoskeleton prob04910   Insulin signaling pathway prob04912   GnRH signaling pathway prob04915   Estrogen signaling pathway prob04917   Prolactin signaling pathway prob04926   Relaxin signaling pathway prob04935   Growth hormone synthesis, secretion and action prob05034   Alcoholism prob05160   Hepatitis C prob05161   Hepatitis B prob05163   Human cytomegalovirus infection prob05165   Human papillomavirus infection prob05200   Pathways in cancer prob05205   Proteoglycans in cancer prob05206   MicroRNAs in cancer prob05207   Chemical carcinogenesis - receptor activation prob05208   Chemical carcinogenesis - reactive oxygen species prob05210   Colorectal cancer prob05211   Renal cell carcinoma prob05213   Endometrial cancer prob05214   Glioma prob05215   Prostate cancer prob05220   Chronic myeloid leukemia prob05221   Acute myeloid leukemia prob05223   Non-small cell lung cancer prob05224   Breast cancer prob05225   Hepatocellular carcinoma prob05226   Gastric cancer prob05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:prob00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     127217013 (Sos1)    04630 JAK-STAT signaling pathway     127217013 (Sos1)    04068 FoxO signaling pathway     127217013 (Sos1)    04072 Phospholipase D signaling pathway     127217013 (Sos1)    04151 PI3K-Akt signaling pathway     127217013 (Sos1)    04150 mTOR signaling pathway     127217013 (Sos1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     127217013 (Sos1)    04660 T cell receptor signaling pathway     127217013 (Sos1)    04662 B cell receptor signaling pathway     127217013 (Sos1)    04664 Fc epsilon RI signaling pathway     127217013 (Sos1)    04062 Chemokine signaling pathway     127217013 (Sos1)   09152 Endocrine system    04915 Estrogen signaling pathway     127217013 (Sos1)    04917 Prolactin signaling pathway     127217013 (Sos1)    04926 Relaxin signaling pathway     127217013 (Sos1)    04935 Growth hormone synthesis, secretion and action     127217013 (Sos1)   09156 Nervous system    04722 Neurotrophin signaling pathway     127217013 (Sos1)   09159 Environmental adaptation    04714 Thermogenesis     127217013 (Sos1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     127217013 (Sos1)    05206 MicroRNAs in cancer     127217013 (Sos1)    05205 Proteoglycans in cancer     127217013 (Sos1)    05207 Chemical carcinogenesis - receptor activation     127217013 (Sos1)    05208 Chemical carcinogenesis - reactive oxygen species     127217013 (Sos1)    05231 Choline metabolism in cancer     127217013 (Sos1)   09162 Cancer: specific types    05210 Colorectal cancer     127217013 (Sos1)    05225 Hepatocellular carcinoma     127217013 (Sos1)    05226 Gastric cancer     127217013 (Sos1)    05214 Glioma     127217013 (Sos1)    05221 Acute myeloid leukemia     127217013 (Sos1)    05220 Chronic myeloid leukemia     127217013 (Sos1)    05211 Renal cell carcinoma     127217013 (Sos1)    05215 Prostate cancer     127217013 (Sos1)    05213 Endometrial cancer     127217013 (Sos1)    05224 Breast cancer     127217013 (Sos1)    05223 Non-small cell lung cancer     127217013 (Sos1)   09172 Infectious disease: viral    05161 Hepatitis B     127217013 (Sos1)    05160 Hepatitis C     127217013 (Sos1)    05163 Human cytomegalovirus infection     127217013 (Sos1)    05165 Human papillomavirus infection     127217013 (Sos1)   09165 Substance dependence    05034 Alcoholism     127217013 (Sos1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     127217013 (Sos1)    01522 Endocrine resistance     127217013 (Sos1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH PH_19 PH_10 IQ_SEC7_PH RHG20_PH DUF6018 Takusan Motif Other DBs NCBI-GeneID:  127217013 NCBI-ProteinID:  XP_051033817 LinkDB All DBs Position Unknown AA seq 1319 aa AA seqDB search MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLREVLGY KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSY DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR DVLRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL EEKSEDQDDKECVKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAA LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENILFEENMQPKAGIPI IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR IALENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK RRRVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP NSPRTPLTPPPASGASSTTDVCSVFDSDHSASPFHSRSASVSSINLAKGTDEVPIPPPVP PRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSLSDRTSVSDPPESPPLL PPREPVRTPDVFSNSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQIPSPHGTRRHLP SPPLTQEVDLHSIAGPPVPPRQSTSQLIPKLPPKTYKREQTHPSMHRDGPPLLENAHSS NT seq 3960 nt NT seq  +upstreamnt  +downstreamnt atgcaggcgcagcagctgccctacgaatttttcagcgaggagaacgcgcccaagtggcgg gggctgctggttcctgcgctgaaaaaggttcaggggcaagttcatcctactcttgaatct aatgatgatgctcttcagtatgttgaagaattaattttgcaattattaaatatgctatgc caagctcagccacgaagtgcttcagatgtggaggaacgtgttcaaaaaagtttccctcat ccaattgataagtgggcaatagctgatgcccaatcagctattgaaaagaggaagagaaga aaccctttatctctgccagcagaaagaattcatcatttactaagggaggttctaggttat aaaattgaccaccaggtttctgtttacatagtagcagtattagaatatatttctgcagat attttaaagctggtggggaattatgtaagaaatatacggcattatgaaattacaaaacaa gacattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta gaagatataaatatcttatctttaactgatgaagagccttccacctcaggagaacaaact tactatgatttggtaaaagcattcatggcagaaattcgacagtacataagagaattaaat ttaattataaaagtttttcgagaaccctttgtctctaattccaaattgttttcatcttat gatgtagaaaacatatttagtcgtatagtagatatacatgaacttagtgtaaagttactg ggccatatagaagacactgtagagatgacagatgaaggcagtccccatccattagtagga agctgttttgaagacttagcagaggaactagcatttgacccatatgaatcatatgctcgg gacgttttacggcctggattccatgaccgtttccttagtcagttatcaaagcctggggca gcactttatttgcagtcaataggcgaaggcttcaaagaagctgtccagtatgtgctgccc cggctgctgcttgcccctgtgtaccactgtctgcattactttgagcttctgaagcagtta gaagaaaagagtgaagatcaagatgacaaggaatgtgtgaaacaagcaataacagctctg cttaatgtccaaagtggcatggaaaaaatatgctccaaaagccttgcgaaacgaagactg agtgagtctgcatgtcgcttttatagccagcaaatgaaggggaaacaactagcaatcaag aaaatgaacgagattcagaagaatattgatggttgggaggggaaagacattggacagtgt tgcaatgagttcataatggaaggaacgcttacccgtgtaggagccaagcatgaaagacac atatttctcttcgatggcttaatgatttgctgtaagtcaaatcatggtcagccaagactt ccaggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgcgtaaggtacaa attaatgataaagatgacaccagtgaatacaagcatgcttttgaaataattctgaaagat ggaaatagtgttatattttctgccaagtcagctgaagaaaagaacaactggatggcagca ctgatatctttgcagtatcggagtaccctagagcgaatgctcgatgtaacaatgctacag gaagagaaagaggagcagatgaggctacctagtgctgatgtgtacaggtttgcagagcca gactctgaggagaatattctgtttgaagagaacatgcagcccaaggctgggatcccaatt atcaaagcagggactgtgattaagctgatcgagaggcttacataccatatgtacgcagat cctaattttgttcggacatttcttacaacatacagatccttttgcaaacctcaagaatta ctgagtcttataatagaacgatttgaaattccagagcctgagccaacagaagctgatcgc atagctctagagaatggagaccagcccctgagtgcagagctgaagaggtttagaaaggaa tatattcagcctgtccaactgcgagtgttaaatgtatgtcggcactgggtggagcaccat ttttatgactttgaaagagatgcagaccttttacaacgaatggaggaatttattggaaca gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaagataatccaaaggaaa aaaattgcaagagacaatggcccaggtcataatattacatttcagagttcacctcccaca gttgagtggcacataagcagacctgggcacatagagacttttgacttgctcaccttacac ccaatagaaattgctcgacaactcactttgcttgaatcagatctataccgagctgtgcag ccatcagaattagttggaagtgtgtggacaaaagaagataaagaaattaattctcctaac cttctgaaaatgatacggcacactactaacctcactctgtggtttgaaaaatgtattgta gaaacagaaaacttagaagaaagagtagctgtggtgagtcggataattgagattctacaa gtctttcaagaactgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactca tcccctgtttataggctagaccacacatttgagcaaataccaagtagacaaaagaaaatt ttagaagaagctcatgagttgagtgaagatcactataagaaatatttggcaaaactcagg tctattaatccaccatgtgtgcctttctttggaatatatctcactaatatcttgaaaaca gaagaaggcaaccctgaagtcctgaaaagacatgggaaagagctcatcaactttagcaaa aggaggagagtggcagagataacaggggagatccagcagtaccaaaaccagccatactgt ttacgggtcgagtcagatatcaaaaggttctttgaaaacttgaatccaatgggaaatagc atggagaaagaatttacagactatcttttcaacaaatccctagaaatagaaccacggaac cctaagcctctcccaagatttccaaaaaaatacagctatcctctaaaatcccctggtgtc cgtccgtcaaacccgagaccaggaaccatgaggcaccccacacctctgcagcaggagcca agaaaaattagttacagtagaatccctgaaagtgagactgaaagtacagcctctgcacca aattctccaagaacaccactgacacctcctcctgcgtccggtgcctctagcaccacagat gtttgcagcgtgtttgattctgaccattcagcaagccctttccactcaagatctgcttcg gtctcatctataaatttagccaagggcactgatgaagtgcccatcccacctcctgttccc cctcgaagacggccagaatctgccccagcagaatcctccccatctaagattatgtctaag cacttggacagccccccagctattcctcctagacaacccacatcaaaagcctattcacca agatactcactatcagatcggacctctgtatcagaccctcctgaaagtcctcccttgtta ccaccacgagaacctgtgagaacgcctgatgttttctcaaactcaccattacatctccaa cctccccctttgggcaaaaagagtgatcatggcaatgctttcttcccaaatagcccttcc ccctttacaccaccacctcctcaaattccgtctccacatggtacaagaaggcatctgcca tcaccaccgctgacacaggaagtggacctccattccattgctgggcctcctgttcctcca cgacaaagcacttctcaacttatccctaaacttcctccaaaaacttataagagggagcaa acacacccatccatgcacagagatggaccaccactgttggagaatgcccattcttcctga

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