Phodopus roborovskii (desert hamster): 127221086
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Entry
127221086 CDS
T08852
Symbol
Pde8b
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob00230
Purine metabolism
prob01100
Metabolic pathways
prob04927
Cortisol synthesis and secretion
prob04934
Cushing syndrome
prob05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
127221086 (Pde8b)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
127221086 (Pde8b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
127221086 (Pde8b)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
127221086 (Pde8b)
Enzymes [BR:
prob01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
127221086 (Pde8b)
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Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DHH
DUF4194
Motif
Other DBs
NCBI-GeneID:
127221086
NCBI-ProteinID:
XP_051038950
LinkDB
All DBs
Position
Unknown
AA seq
885 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQTSSLSQGPTAPLHGLFVQTDAADAMPPSRAVG
PPGAVRVRRSRAELGSGSSTGSSGPAVTTCRGRRRHCCSGAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASDDHEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCATDHNKQIHRIHRDSGDNSQTEPPSFRHKSRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITI
NDVPPSITQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCTETTLRAW
LQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPLAAESEGSDCECNPTGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccatgtctcacagagcggcgtgatatactgccgggactca
gatgagtccaactcgccccgccagaccagcagcctgtcgcagggccccacggcgcccctg
cacggcctcttcgtgcagaccgacgccgccgacgccatgcccccgagccgcgcggtggga
cccccgggcgctgtccgagtccgtaggtcccgggctgagctgggcagtggcagtagcacg
gggtcctcggggccagctgtgaccacctgccggggccggaggcgacactgctgcagcggc
gctgaggccgagacccagaccagctacaccagtgtcaagcaggtgtcttcagcggaggta
cgcattggacccatgagactgacacaggaccctatccaggttttgctaatctttgcaaag
gaggatagccagagtgatggcttctggtgggcctgtgacagggctggctaccgatgcaac
attgctcgcactccagagtcagcccttgaatgtttcctggacaagcatcatgaaatcatt
gtgattgatcacaggcaaacccggaacttcgatgcagaagcggtgtgcaggtcaatccgg
gccactaacccttctgagcacactgtgatcctggctgtggtttcacaagcatctgatgac
cacgaagaggcctccgttcttcctcttctccacgcaggcttcaaccggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcacagttcaaattacgggcctgtaattcagtgtttacagcgttagaccactgtcatgaa
gccatagagattacaagtgatgatcatgtgattcagtatgtcaaccctgcctttgagagg
atgatgggctaccacaaaggggagcttctggggaaagaactcgctgacctacctaagagt
gacaagaaccgggcagacctcctggacaccatcaatacgtgcatcaagaagggaaaggag
tggcagggggtttactatgccagacggaaatccggggacagcatccaacagcacgtgaag
atcaccccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaagctg
tgctgtgccactgaccataacaagcagattcacaggattcatcgtgactctggggataac
tctcaaacagagccgccttcattcagacacaagagcaggaggaaagagtccattgatgtg
aaatcaatatcttctcgcggcagcgatgctccaagcctacagaatcgccgctacccctcc
atggcaaggatccactccatgaccatagaggcccccatcacaaaggttatcaatataatc
aatgcagctcaagaaaacagcccagttacagtagcagaagccttggacagagttctagaa
attttacggaccacagaactgtactcccctcagctgggaaccaaagatgaagatcctcac
accagtgaccttgttggaggcctgatgaccgatggcttgagaagactgtcagggaatgag
tatgtgttcacaaagaatgtgcaccagagtcacagtcaccttgcgatgcccataaccatc
aatgatgtcccccctagtatcacccagttactggacaatgaggaaagttgggacttcaac
atctttgaattggaagcagttacacataaaaggccactggtgtacctgggcttaaaggtc
ttctctcggtttggagtatgtgaatttttaaactgcacggaaaccactcttcgggcctgg
ctgcaagtgattgaagccaactaccactcctccaatgcctaccacaattccacccatgct
gccgatgtcctacatgccacagctttcttccttggaaaggaaagagtgaagggaagcctc
gaccagctggatgaggtggctgctctgattgctgcaacagtccacgatgtggatcaccct
ggaagaaccaactccttcctgtgcaatgcaggcagtgagttggctgtgctctacaatgac
actgcagtcttggagagccaccacacggccctggccttccagctcactgtcaaggacact
aagtgcaacatcttcaagaacattgacaggaaccattaccgaacgctacgccaggctatt
atcgacatggttttggccacagagatgacaaaacactttgaacatgtgaacaaatttgtg
aacagcatcaacaagccactggcagctgagagcgagggcagcgactgtgaatgcaaccct
acgggaaagaacttcccagaaaaccaaatcctgatcaagcgcatgatgatcaagtgtgct
gatgttgccaacccatgccgacccttggacctgtgcattgagtgggcggggaggatctcc
gaggagtactttgcacagactgatgaggagaagagacaggggctacctgttgtgatgcca
gtgttcgaccgtaatacctgcagcattcccaagtcccagatctccttcatcgactacttc
ataacggacatgtttgatgcttgggacgcctttgcacacctgccggccctgatgcagcac
ttggcagataactacaaacactggaagacactagatgacctcaagtgcaaaagtctgaga
cttccgtctgacagctaa
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