Phodopus roborovskii (desert hamster): 127222680
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Entry
127222680 CDS
T08852
Symbol
Setx
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
127222680 (Setx)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
prob03021
]
127222680 (Setx)
Enzymes [BR:
prob01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
127222680 (Setx)
5.6.2.5 RNA 5'-3' helicase
127222680 (Setx)
Transcription machinery [BR:
prob03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
127222680 (Setx)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
AAA_22
nSTAND3
ResIII
AAA_16
Helicase_RecD
Motif
Other DBs
NCBI-GeneID:
127222680
NCBI-ProteinID:
XP_051040952
LinkDB
All DBs
Position
Unknown
AA seq
2694 aa
AA seq
DB search
MSTCCWCTPGGASTVDVLKCYASSTESSEFQTADEDLCYCLECVAEYHRARDEVPFLHEV
LWELETLRLINHFEKSMKAEVEDDELYIVDNNGEEQLFDCSGQDFENKLRVPLFEILKYP
YLLLHERVNELCVEALCRMEQANCSFQVFDKYPGIYLFLVHPNEMIRRWAILTARNLGKV
DRDDYYDLQEVLTCLFKVIELGLLESPDLYTSSVLEKGKLILLPAHMYDTTNYKNYWLGI
CMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDSKDPFWPALHCFMVILDRLG
SKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSIRTKSEPEPHFDDMVTCSQIVYNYNP
EKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMDL
KDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFILILVSVIELHRNKKCLHLLWVS
SQQWVEAVVKCAKLPTSAFARSSEKSPGSTPKGAAIISSLPLHSVPSNSVQLSCVQLIRG
LLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTAQETHELQLCLKQIIRNIKFKMPQ
YSTFGDLTSTCKNPPSFKEESEQIDRKPKKDIYCLENCSPTCSKEPVKADSNQILIKAND
TEEESIKQHYIDLNEEEPLPAKLCLKQESEAFFYGSAQEQVKISTEKSLKENSSYTPQNN
TLRNGSEWGCDRGVIISTRSLSDSSTDSLEKVSTSNEDVSLKDDTVGKNSKPKSKAQKDE
ICAKLSHVIKKQHRKSTLINNIINLEENTVMSDPENSSGKDRGVLKEDTITHDVSSDPVL
DGEHAEQNSENSSLLKKKQLKNEESNNFDENKCQIQEYHGTGDLLSFTEVTNTLVKKMSC
EGPVKVVVESRDKEIRKSMVLTSDVVKEQVLHGSNKPLVTGSQMDLCNMTLKAQTTVIQF
PSGSSKSPPQLQRKDDRRCLTPNHNNSDTCHGQIIVISDSDEDDDERRHGIEKHTKQGKV
CTEKERPEQHGLVVNTGMEKKLIKEEETKCPVEFEDSESQVFEFESSSEVYSVWQDHNID
SKNFQEEGKSCVTYVADSTNSSLGCGADFVSEEVTRNEAEDVEEHAEPHSSVSAEEFCKT
GGKKHKRKRCDRVTAEDPQRPSSSVRPEQLADDRDLARIDTGTSASISNVERDSTVSPMK
STKPRTHSKPVRKVPASKAIKKIHSDTKRGQNKSSCYITCRTSPAIVPPKKFRQCPEPTS
TVEKLGLKKAPRKAFELSQRSLECIFQLRDHGKTVGVVDAPKKTKLISQTLSIKNNKKLL
TSQDLQFQRLMRSRSHQKRDLDYKNNDIGRIVPQTVQGSHVPAPDSDGPDNHRGSEPPAN
SNEKQLTKCMPSKPEVAKVISDPQVTDITSLVNQCESRVLSGGVPTDVTVFASEDPVGGD
AHIMPVGEVAAVKAAEPESSSDTDDDNLFLTQHDPQDMDLCSQMENNKLIIVAHKDAVQR
ENSVSQPQLESLSVTKCKYKDCVETTKNQGEYCPRHSEAKAADDDVFRKPGLPLSVARPL
RPTTTKIFSSSSASRTANLSKSLENTILQSALKNKSSGAQPNLKVTPSSCLVSQKPVAEV
KSLCNIFNFQTPSSSNKQSYKFILSDSKPVSASSPVNSLLPSQSIFDTFIKEVLKWKYQM
FLNFDKCGAPTSLSQSISRPVPVRFQDCAEYFSVFLPLIILNAFETVAQEWFNSPNKENF
YHLHLRKFPADYKKYWEFMIYLEESELAKQLHPKENDLVFLVPERLNREKKDMNKNVMQD
RIGYYCGYVHKFRRTSIMRSGKTECSLCIQTQDNLPARLNEFTKCIVISSLVTTQRKLKA
MSLLSSRNQLARAVLNPNPMDFCTKDLLTTTSERIITYLKDFNEDQKKAIETAYAMVKHS
PSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHYDENFNAKIKQNRVLVCAPSNAA
VDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINTEVLKFSLDSQVNHRMKKD
LPSHIQELLERKEFLDGQLDELSRQRALCRGGREMQRQELDRHIVKVAKERQELASKIKE
VQGRPQKTQNTIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETL
SPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCKLLEENVEQNMIGRLPVL
QLTIQYRMHPDICLFPSNYVYNKNLKTNRMTEAIRCSSEWPFQPYLVFDVGDGSERRDND
SYINVQEIKLVMEIIRLIKEKRKDISSRNIGIITHYKAQKTMIQKDLEKEFDKKGLLQPI
MMGESRQQDPEVSSQKKKSSECMHTSDELDFSTITQSGVSCVENGVTHTGPAEVDTVDAF
QGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWYEL
IQDAQKRGAIIKTCDPNYRHDAMKILKLKPVLQRSLTHPPATAPEAPRPQGGLPGNKLDS
GLAKTSFAASLYHTPSDAVTSKEPERPSLQDRLRDPRLLRRLNAEAKGSFLKNAQFLNPQ
LAGVVHCLLGEPGIPGMSQDLSYIVPPSTAIVAPMNSHRSPLQAEPPPAHPAAPSTSKRK
YSDRDSGYSHRRQPRAFNEEERRGSVTHHMLRSTDCSRRRLEQEDSSAKKRRFL
NT seq
8085 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgctgttggtgtactccaggtggtgcttccaccgttgatgtcctgaagtgc
tatgcatctagcactgaatcaagtgaatttcaaacagctgatgaagacctctgctactgc
ttagaatgtgtggctgagtaccacagagccagagatgaggtgccattcttgcatgaggtt
ttatgggaactagaaaccttacgcctcataaatcactttgagaagtctatgaaggcagaa
gttgaagatgatgagttatatatagtggacaacaatggagaagaacaactatttgactgt
agtggccaagattttgaaaataagcttcgagttcctctttttgaaatactgaagtaccct
tacttgcttctgcatgagcgtgttaatgaactgtgtgtggaagcactttgtcgaatggaa
caagcgaattgctcctttcaggtttttgacaagtatccagggatctatttgtttttggtt
catcctaatgaaatgattcggcgatgggctattctgactgcaagaaacctagggaaagtg
gacagagatgactattacgacttacaggaagttttaacttgcctttttaaagttattgag
ttggggcttttggaaagtccagacctttacacgtcttctgtgcttgaaaaaggcaaactg
atccttctgcctgcgcacatgtatgatactaccaactacaaaaactactggctaggtatt
tgcatgttgctgactattcttgaggagcaagcaatggattcactgttgttgggctcagac
aaacaaaatgattttatgcaatcaattcttcacaccatggagaggcaatcagatgatgac
agtaaggatcctttctggccagcattacactgtttcatggtgattctggatcgacttgga
tctaaggtgtggggtcagcttattgaccctattgaagcatttcaaaccatcattaacaat
gtgagctacaacagagagatccaaaatatacggaacagctccataaggaccaagtcagaa
ccagagccacattttgatgatatggtaacatgcagccagattgtctataactataaccct
gagaagactaaaaaggattcagggtggagatcagccatttgtccagattattgtcctaac
atgtatgaagaaatggaaacattagccaatgtacttcagtcagatattggtcaagatatg
cgtgttcataacagtacctttctgtggttcataccttttgttcagtcactcatggatctt
aaggatttgggtgtggcttacattgtagaagttattcatcatctatactctgaagtcaaa
gatgtcctcaaccagacagatgctgtgtgtgacaaagtcactgaattttttattctgatt
ttagtatctgtgattgaactgcatagaaataaaaaatgtttgcatctgctatgggtgagt
tcgcaacaatgggtggaagctgttgtgaagtgtgccaagcttcctactagtgcatttgca
cggagttctgagaagtcacctggaagtaccccaaagggagcagcaataatatcatcactg
ccattgcattcagtgccctctaactctgtccaactatcttgtgttcagttgattaggggc
ctcctaaaagaaggttatcagcttggtcagcaaacactttgtaagcggttttgggataaa
ctgaacttattccttcgaggaaatttatctctgggttggcagttgactgctcaagaaacc
catgagttacaattgtgcttgaaacaaataattagaaacataaaattcaaaatgccccag
tatagcacttttggggatctgacttctacatgtaaaaatcctccatcttttaaagaagaa
agtgaacaaatagacaggaagcctaaaaaagacatttattgcctggaaaattgcagcccc
acatgttctaaagaaccagtgaaagctgacagcaatcaaatattgattaaagcaaatgat
acagaagaggagagcatcaaacagcactatattgatttgaatgaagaagagcctcttcca
gctaaattatgcttgaagcaggagagtgaggcctttttttatggaagtgctcaagagcaa
gttaaaataagtacagagaagtccttaaaagaaaactcttcatatacaccacaaaataat
acattaagaaatggctcagaatggggatgtgacagaggagtaataatatcaacacgttca
ttgtctgattctagcactgattctctggaaaaagtatctacatcaaatgaagatgtctca
ttaaaggatgatactgttggtaaaaactcaaaaccaaagtctaaagcacagaaagatgaa
atttgtgcaaagttatcacatgtcataaagaagcaacacaggaaaagtactttgatcaat
aacattatcaatctagaggaaaatacagttatgtctgatcctgagaacagttcaggaaaa
gatagaggagttctgaaggaagacactatcacacatgatgtgtcttcagaccctgttctg
gatggtgaacatgcagagcaaaattctgaaaacagttcattgttaaaaaagaaacagtta
aaaaatgaggagtcaaacaattttgatgaaaacaagtgtcaaattcaggaataccatggt
actggtgatttgctgtcatttacagaagttaccaatacattggtaaagaaaatgtcatgt
gagggtcctgtaaaagttgtagttgaatcaagagataaggaaataagaaagagcatggtg
ctgacttctgacgttgtaaaagaacaggtgcttcatggcagtaataagcctttggtaaca
ggttctcaaatggacctctgtaacatgactttaaaagctcaaaccactgttattcaattt
ccatcaggttcaagtaaaagtcctcctcagctgcaaagaaaagatgatagaagatgtttg
acacctaaccataacaattctgacacctgccatgggcagattattgttatttcagattct
gatgaagatgatgatgaaagaaggcatggtattgagaaacacaccaaacagggcaaagta
tgcacagagaaagaacgtccagagcagcatggtttggtagttaatactggtatggaaaag
aagcttataaaggaagaagaaacaaagtgccctgtagaatttgaggactctgaatctcag
gtttttgagtttgaaagttcttctgaagtatattcagtttggcaagatcataacatagac
agcaagaactttcaagaggaaggaaaaagctgtgtaacttatgtagctgatagtacaaac
agtagtttgggttgtggtgcagactttgtgtctgaagaggttactagaaatgaagcagag
gatgttgaagaacatgcagaaccacacagtagtgtttctgctgaggaattttgtaaaact
ggaggaaaaaaacataagagaaaacgatgtgacagagttacagctgaagatccccaaagg
ccttcatcttctgtcagacctgagcaattggctgatgaccgagatcttgctagaatagac
acaggcacatcagcttccatttcaaatgttgagagagattctacagtttcaccaatgaag
tctacaaagcctcgtactcactcaaaacctgttaggaaagttccagcttctaaggctatt
aagaaaattcattcagacaccaagagaggacagaataagagttcatgttacatcacttgt
agaacatcacctgctattgtgccaccaaagaaatttcgtcagtgtccagagccaacttca
acagttgaaaaacttggtctgaaaaaagctcctcggaaggcatttgagttgtcccagagg
tctctggagtgtatattccaattacgtgaccatggtaagactgttggagtagttgatgcc
cccaaaaagactaaattaatttctcagactctttccatcaaaaataataagaagctgctg
acaagtcaggatcttcagtttcaaaggctcatgagatctagatcacatcaaaaacgagac
cttgattacaaaaataatgatattgggaggatagtaccacaaacagtacagggttctcat
gtacctgcaccagactctgatgggccagataatcatagaggaagtgagccacctgccaac
agtaatgaaaagcaattaacaaaatgtatgccttccaaaccagaagtggcaaaagtgatt
tctgatcctcaggtgactgatataacttctcttgtgaaccagtgtgagtctagagtgtta
agtggaggagtgccaacagatgtgaccgtatttgcttcagaggatcctgtgggtggagat
gctcacataatgccagttggggaggtggcagctgtgaaagctgcagaaccagaatccagt
agcgatacagatgatgacaatttattcctaacacagcatgatcctcaagatatggatctg
tgctcacagatggaaaataataaactgattatagtggctcataaagatgctgttcagagg
gagaattctgtaagtcagcctcagctggagtctttgagtgttacaaagtgtaagtataaa
gactgtgttgaaaccacgaaaaaccagggtgaatactgcccaagacactctgaagctaaa
gcagcagatgatgatgtgtttcgtaaacctggcttacctctttctgtagccagacccttg
agacctacgactaccaagatatttagctcaagcagtgcttcacgaactgccaatctttct
aagtctttggaaaatactatacttcagtctgcactgaaaaataagtcaagtggggcacag
cctaatttgaaggtgacaccatcctcttgtctagtgtctcagaagccagtggctgaggtg
aaaagtttatgcaatatttttaattttcaaactccaagcagttctaataaacagagttac
aagtttatacttagtgacagcaagcctgtgtcagcttcctctccagtgaacagtctcttg
ccatcacagtctatctttgacaccttcattaaagaggtcttaaaatggaaataccaaatg
tttttgaactttgataaatgtggtgccccaacaagtctctctcagtctatctcaagaccc
gtgcccgtccgatttcaagattgtgcagagtattttagtgtttttctccctttgattata
ttgaatgcttttgaaacagtggcacaggaatggttcaactctccaaataaagagaatttc
tatcatttgcatttacgaaaatttccagccgactataaaaaatactgggagtttatgatt
tacctggaggaatctgaactagctaaacagcttcatccaaaggaaaatgatctggtgttt
ttggttcctgagagactaaatagagagaagaaagatatgaacaagaatgtcatgcaagat
cgaattggctactattgtggttatgttcataagtttcgccgtacttcaatcatgcgcagt
ggaaaaactgagtgttccttgtgcatccagacacaagataacttgccagccagactaaat
gaattcacgaaatgtattgtaattagttctctggtaactacacagaggaaattgaaagcc
atgtctctgttgagcagtcggaaccagttggccagagctgttctaaatccaaaccccatg
gatttctgtaccaaagatctattaactacaacatctgaaagaattattacctacttaaaa
gacttcaatgaagaccagaagaaagccatagaaacagcatatgctatggtgaaacactca
ccatccgttgccaaaatctgtttgattcatggaccacctggaacaggaaaatcaaaaacc
attgttggtctcttgtaccgcttattgacagagaaccagaggaagggccattatgatgaa
aacttcaatgccaaaatcaagcaaaatcgagtccttgtgtgtgcaccttccaatgcagct
gttgatgaacttatgaaaaaaattatcctcgaattcaaagaaaaatgtaaagacaagaag
aatcctttgggaaattgtggagatataaatttagtacgactgggtccagaaaaatctatt
aatactgaggtcctaaaattcagtttggacagccaagtcaaccacagaatgaaaaaagac
ttgccttctcatatccaagaactgcttgaaagaaaagagtttctagatggtcaacttgat
gagctttcacgtcagcgagctctgtgtcgaggtgggcgagagatgcagaggcaagaacta
gatagacatattgtcaaagttgcgaaagaaaggcaagaacttgcttcgaaaattaaagag
gttcaggggcgcccacagaaaacacagaataccatcatcttggagtctcatgtcatctgc
tgtacattgagcacaagtggtggtttgctgcttgagtctgcttttcgagggcaagggggt
gtcccctttagttgtgtcattgttgatgaggctggacagtcttgtgaagttgagacactt
tctccacttatccatcgttgcaacaaacttatcctagtaggagatcccaaacagctccct
ccaacggtcatttctatgaaagcacaggagtatggttatgaccagtcaatgatggcacga
ttctgcaagctgcttgaagagaatgtggagcagaacatgattggcaggctgccagtttta
cagcttaccattcagtacaggatgcatccagacatatgtctcttcccttctaattatgtt
tataacaaaaacttgaaaacaaatagaatgactgaagccattcggtgttcatcagagtgg
ccatttcagccctaccttgtgtttgatgttggagatggttcagaacgacgggataatgac
tcctacataaatgttcaagaaataaagttggtgatggaaataattagacttattaaagag
aaaagaaaagatatttcctcccgaaatattggcataataactcattacaaggctcagaag
acgatgatccagaaggatttggagaaagaatttgataagaaaggtttattacagcccatc
atgatgggagagtcaaggcagcaggaccctgaagtatccagtcagaagaagaagagcagt
gaatgcatgcatactagtgatgagctcgatttctccactattacacagtccggagtctcc
tgcgtagagaatggtgtcacccacactgggcctgcagaagtggatacagtggatgctttc
cagggccggcagaaagactgcataatcgttacttgtgtcagggcgagtgctgtgcaaggt
tcaattggattcctggcaagtttgcagagattgaatgtcaccattacgcgagccaagtac
agccttttcatccttggacatttgaggactctgatggaaaaccaacattggtatgaactg
attcaggatgctcagaagcgtggggccattattaagacctgtgacccaaactatagacat
gatgcaatgaaaattctgaaactgaagcctgtgctgcagaggagtctgacccatcctcca
gccactgccccagaggcaccgagacctcagggtggcttgcccggcaacaaactggacagt
ggacttgccaagacatcttttgctgcttctctgtaccatacaccctctgatgctgtcact
tcgaaggaacctgaaaggccatctcttcaagacagacttcgagatccacgactgcttagg
agattgaatgctgaagctaaagggtcattcctgaaaaatgcacagtttctgaacccccag
ctcgctggggtagtccattgtctcctgggagagcctggcattcctgggatgtctcaggac
ctgagttatattgtgccaccatccactgccatcgttgcccccatgaacagccacaggtct
cctcttcaggctgagccaccacctgctcaccctgctgctccttccacaagtaagaggaag
tacagtgaccgggactctgggtacagtcacagaaggcaacccagggccttcaatgaagag
gagagacgtggctctgtgactcatcacatgctgagaagtactgactgtagtaggaggaga
ctggaacaggaggacagcagtgctaagaagaggcgctttctatag
DBGET
integrated database retrieval system
