KEGG   Phodopus roborovskii (desert hamster): 127222787
Entry
127222787         CDS       T08852                                 
Symbol
Gnas
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
prob  Phodopus roborovskii (desert hamster)
Pathway
prob01522  Endocrine resistance
prob04015  Rap1 signaling pathway
prob04020  Calcium signaling pathway
prob04024  cAMP signaling pathway
prob04072  Phospholipase D signaling pathway
prob04081  Hormone signaling
prob04082  Neuroactive ligand signaling
prob04261  Adrenergic signaling in cardiomyocytes
prob04270  Vascular smooth muscle contraction
prob04540  Gap junction
prob04611  Platelet activation
prob04713  Circadian entrainment
prob04714  Thermogenesis
prob04724  Glutamatergic synapse
prob04726  Serotonergic synapse
prob04728  Dopaminergic synapse
prob04730  Long-term depression
prob04750  Inflammatory mediator regulation of TRP channels
prob04911  Insulin secretion
prob04912  GnRH signaling pathway
prob04913  Ovarian steroidogenesis
prob04915  Estrogen signaling pathway
prob04916  Melanogenesis
prob04918  Thyroid hormone synthesis
prob04921  Oxytocin signaling pathway
prob04922  Glucagon signaling pathway
prob04923  Regulation of lipolysis in adipocytes
prob04924  Renin secretion
prob04925  Aldosterone synthesis and secretion
prob04926  Relaxin signaling pathway
prob04927  Cortisol synthesis and secretion
prob04928  Parathyroid hormone synthesis, secretion and action
prob04934  Cushing syndrome
prob04935  Growth hormone synthesis, secretion and action
prob04961  Endocrine and other factor-regulated calcium reabsorption
prob04962  Vasopressin-regulated water reabsorption
prob04970  Salivary secretion
prob04971  Gastric acid secretion
prob04972  Pancreatic secretion
prob04976  Bile secretion
prob05012  Parkinson disease
prob05030  Cocaine addiction
prob05031  Amphetamine addiction
prob05032  Morphine addiction
prob05034  Alcoholism
prob05142  Chagas disease
prob05146  Amoebiasis
prob05163  Human cytomegalovirus infection
prob05165  Human papillomavirus infection
prob05200  Pathways in cancer
prob05207  Chemical carcinogenesis - receptor activation
prob05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:prob00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    127222787 (Gnas)
   04020 Calcium signaling pathway
    127222787 (Gnas)
   04072 Phospholipase D signaling pathway
    127222787 (Gnas)
   04024 cAMP signaling pathway
    127222787 (Gnas)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    127222787 (Gnas)
   04081 Hormone signaling
    127222787 (Gnas)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    127222787 (Gnas)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    127222787 (Gnas)
  09152 Endocrine system
   04911 Insulin secretion
    127222787 (Gnas)
   04922 Glucagon signaling pathway
    127222787 (Gnas)
   04923 Regulation of lipolysis in adipocytes
    127222787 (Gnas)
   04912 GnRH signaling pathway
    127222787 (Gnas)
   04913 Ovarian steroidogenesis
    127222787 (Gnas)
   04915 Estrogen signaling pathway
    127222787 (Gnas)
   04921 Oxytocin signaling pathway
    127222787 (Gnas)
   04926 Relaxin signaling pathway
    127222787 (Gnas)
   04935 Growth hormone synthesis, secretion and action
    127222787 (Gnas)
   04918 Thyroid hormone synthesis
    127222787 (Gnas)
   04928 Parathyroid hormone synthesis, secretion and action
    127222787 (Gnas)
   04916 Melanogenesis
    127222787 (Gnas)
   04924 Renin secretion
    127222787 (Gnas)
   04925 Aldosterone synthesis and secretion
    127222787 (Gnas)
   04927 Cortisol synthesis and secretion
    127222787 (Gnas)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    127222787 (Gnas)
   04270 Vascular smooth muscle contraction
    127222787 (Gnas)
  09154 Digestive system
   04970 Salivary secretion
    127222787 (Gnas)
   04971 Gastric acid secretion
    127222787 (Gnas)
   04972 Pancreatic secretion
    127222787 (Gnas)
   04976 Bile secretion
    127222787 (Gnas)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    127222787 (Gnas)
   04961 Endocrine and other factor-regulated calcium reabsorption
    127222787 (Gnas)
  09156 Nervous system
   04724 Glutamatergic synapse
    127222787 (Gnas)
   04728 Dopaminergic synapse
    127222787 (Gnas)
   04726 Serotonergic synapse
    127222787 (Gnas)
   04730 Long-term depression
    127222787 (Gnas)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    127222787 (Gnas)
  09159 Environmental adaptation
   04713 Circadian entrainment
    127222787 (Gnas)
   04714 Thermogenesis
    127222787 (Gnas)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127222787 (Gnas)
   05207 Chemical carcinogenesis - receptor activation
    127222787 (Gnas)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    127222787 (Gnas)
   05165 Human papillomavirus infection
    127222787 (Gnas)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    127222787 (Gnas)
   05142 Chagas disease
    127222787 (Gnas)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    127222787 (Gnas)
  09165 Substance dependence
   05030 Cocaine addiction
    127222787 (Gnas)
   05031 Amphetamine addiction
    127222787 (Gnas)
   05032 Morphine addiction
    127222787 (Gnas)
   05034 Alcoholism
    127222787 (Gnas)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    127222787 (Gnas)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    127222787 (Gnas)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    127222787 (Gnas)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:prob04147]
    127222787 (Gnas)
   04031 GTP-binding proteins [BR:prob04031]
    127222787 (Gnas)
Exosome [BR:prob04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   127222787 (Gnas)
  Exosomal proteins of other body fluids (saliva and urine)
   127222787 (Gnas)
  Exosomal proteins of colorectal cancer cells
   127222787 (Gnas)
  Exosomal proteins of bladder cancer cells
   127222787 (Gnas)
GTP-binding proteins [BR:prob04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    127222787 (Gnas)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA
Other DBs
NCBI-GeneID: 127222787
NCBI-ProteinID: XP_051041188
LinkDB
Position
Unknown
AA seq 1123 aa
MGMCNRLHGNDMPGQHDIPGEVGEQPEQEPLEAPGAAAPGAGLGPAEEMETEPSDNEPIP
DEAGLEGYGPPGVSGADFQGLSQAFEEVAVGGNYSPPPEEAMPFETEQPSLGEFWPFLEQ
PGRSGAQPDLKTFNPALLEPGTPSRANPALGTYSPPPEEAMPFEFNEPAQGDHSQPPLQV
PDLAPGGPEPEVLSALPAEPGNLRFASASFRDDYSPPPEESVPFWPDGEGFGGDSPPPGL
PRVSRQIGIGGEFPTAAVPSALSLAPAASAPPLWVHSAIDRPFGEAIRSPPNFACDSPQM
EISRPPLEIGRASTGVDDDTAVNMDGPPIASVGPPIQVSGAPDKSERAERPPVEREAAEM
EGSPTTAAAVEGEVPSPERRDGSFTQPETMDDKPASAAQTVVNKPDAAAGGSPPAPATPA
ELQTDPEEVGEAPAVRAEPDGGAAPAVPATTAESEGGEDPAAEPASEAVPAAKAESASGA
APVAQVEPEAAEVSATAEPAARAAPVTPPEPAPRPIPTARAHPAAGAVPGAPAMPASARA
TAARAAYAGPLVWGARSLSATPAARACLPARAAAAARAASAARAVAAGHPISVARSMSAS
RAIPAAPSRAHLRPPSPEIQVADPPTPRPAPRPSAWPDKYERGRSGCRYEEVSSVICEID
SSSDESEEGANGCFQYLLRRNRGPGQTRSHTVGCNPVRNFFARTFGSCFGLCERSRSLSP
GKAKDPFEERRKQMRKEAIEMREQKRADKKRSKLIDKQLEEEKMDYMCTHRLLLLGAGES
GKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMS
NLVPPVELANPENQFRVDYILSVMNVPNFDFPPEFYEHAKALWEDEGVRACYERSNEYQL
IDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDER
RKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFL
NKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTA
SGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
NT seq 3372 nt   +upstreamnt  +downstreamnt
atgggcatgtgcaaccgcctccacggcaacgatatgccaggacaacacgatatccccggt
gaagtcggggagcagcccgagcaagaacctttggaggccccaggggcagctgcccccggt
gctgggcttggcccagccgaagaaatggagaccgaaccgtctgacaatgagcccatcccc
gacgaggctggccttgagggctatggaccccctggggtctcaggagccgactttcagggc
ctcagccaggccttcgaggaagtcgcagtgggtggaaactacagcccacctccggaggaa
gccatgccatttgagaccgaacagcccagcctgggagagttctggcccttcctggagcag
cctggaagatctggggcccaaccagacctcaaaaccttcaatccagcgcttttggagccc
gggacccccagtcgtgcgaacccagccctgggaacctatagccccccaccagaagaagct
atgccatttgagttcaacgagcctgcccaaggagaccatagccagccgccattgcaagtc
ccagaccttgcgccaggaggtccggagccagaggtcctcagtgcacttcccgcggagccc
ggcaacctcagatttgcaagcgctagcttccgagatgactacagccctccacctgaagag
tctgtgccgttctggcccgatggagaaggatttgggggcgatagcccacccccaggcctc
ccccgagtcagccgacaaatcggcattggcggcgagttcccgacagccgcggtcccgagt
gcgctcagcctcgctcccgccgcgagcgcgcctcccctctgggtccacagcgccattgac
agaccattcggcgaggctatcagatcgcctcctaacttcgcatgcgacagcccccagatg
gagatctccagacccccgcttgagattggcagagcctccactggggtcgacgacgacacc
gctgtcaatatggacggccccccaatcgcaagtgttggcccgcccatccaagtctccgga
gccccagataagagcgagcgcgcagagagacccccagttgagcgagaagcagccgagatg
gaaggaagccctaccaccgcagctgcggtggaaggagaagtcccttctccggagagaaga
gacggatccttcacccagccagaaaccatggatgacaagccagcctctgctgcccagacc
gtcgtcaacaaacctgatgccgcagccggcggatctcctccggccccagcaacacccgcg
gagctccaaaccgatcccgaagaagtcggagaagcccctgctgtccgcgcggagcctgat
ggaggggcagcgccagccgtcccagccaccaccgccgagtctgaaggtggagaagatcca
gccgctgagccagcctccgaggcagtccctgccgccaaggctgagtctgcctccggggca
gccccggtcgcccaggtggagcccgaagcggcggaagtctctgctacggcagagcctgcc
gcccgggcagcccctgtcacccctccggagcccgctccccggccaatccctactgccaga
gcccatccagctgccggggcggtccctggcgccccggcgatgccagcctccgctagggca
actgccgctagggcagcctatgcaggtcctctggtctggggagccaggtcactctcggct
actcccgccgccagggcatgcctccctgcccgtgcagctgccgccgcccgggcagcctct
gcagcccgggcagttgctgccggccacccaatctctgtcgcccggtccatgtctgcctcc
cgggcaatccctgccgccccaagcagggctcatcttagaccccccagccccgagatccag
gttgctgacccgcctactccgcggcctgctccgaggccgagcgcctggcccgacaagtat
gaacgtggccgaagcggctgcaggtacgaggaggtctcgtccgtcatctgcgagattgac
tcctccagtgatgagtcggaagaaggggccaacggctgcttccagtaccttctgcggcga
aaccgcggccccggccagacccggagccacacggtcggatgcaacccagtccgcaacttc
ttcgccagaaccttcggaagctgcttcggtctctgcgagagatcccgttccctcagccca
gggaaggccaaggatccatttgaggaaagacgcaaacagatgcgcaaagaggccattgag
atgcgagagcagaagcgcgcagataagaaacgcagcaagctcatcgacaagcaactggag
gaggagaagatggactacatgtgtacgcaccgcctgctgcttctaggtgctggagagtct
ggcaaaagcaccattgtgaagcagatgcggattctgcatgttaatgggtttaacggagag
ggcggcgaagaggacccgcaggctgcaaggagcaacagcgatggtgagaaggccaccaaa
gtgcaggacatcaaaaacaacctgaaggaggccattgaaaccatcgtggccgccatgagc
aacctggtgccccctgtggagctggccaaccctgagaatcagttccgagttgactacatt
ctgagcgtgatgaacgtgcccaactttgacttcccacctgaattctatgagcacgccaag
gctctgtgggaggacgagggagttcgtgcctgctatgagcgctccaatgagtaccagctg
attgactgtgcccagtacttcctggacaagattgacgtgatcaagcaggccgactatgtg
ccaagcgaccaggacctgcttcgctgccgcgtcctgacctctggaatctttgagaccaag
ttccaggtggacaaagtcaacttccacatgttcgatgtgggcggccagcgcgatgaacgc
cgcaagtggatccagtgcttcaatgacgtgactgccatcatcttcgtggtggccagcagc
agctacaacatggtcattcgggaggacaaccagaccaaccgcctgcaggaggctctgaac
ctcttcaagagcatctggaacaacagatggctgcgcaccatctctgtgatcctgttcctc
aacaagcaggacctgcttgctgagaaagtcctcgctggaaaatcgaagattgaggactac
tttccagagttcgctcgctacaccactcctgaggatgcgactcccgagcccggagaggac
ccacgcgtgacccgggccaagtacttcattcgcgacgagtttctgagaatcagcactgct
agtggagacgggcgccactactgctacccccacttcacctgcgccgtggacactgagaac
atccgccgcgtcttcaacgactgccgtgacatcatccagcgcatgcatctccgccaatac
gagctgctctaa

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