KEGG   Phodopus roborovskii (desert hamster): 127224653
Entry
127224653         CDS       T08852                                 
Symbol
Src
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
prob  Phodopus roborovskii (desert hamster)
Pathway
prob01521  EGFR tyrosine kinase inhibitor resistance
prob01522  Endocrine resistance
prob04012  ErbB signaling pathway
prob04015  Rap1 signaling pathway
prob04062  Chemokine signaling pathway
prob04081  Hormone signaling
prob04137  Mitophagy - animal
prob04144  Endocytosis
prob04360  Axon guidance
prob04370  VEGF signaling pathway
prob04510  Focal adhesion
prob04520  Adherens junction
prob04530  Tight junction
prob04540  Gap junction
prob04611  Platelet activation
prob04613  Neutrophil extracellular trap formation
prob04625  C-type lectin receptor signaling pathway
prob04727  GABAergic synapse
prob04750  Inflammatory mediator regulation of TRP channels
prob04810  Regulation of actin cytoskeleton
prob04912  GnRH signaling pathway
prob04915  Estrogen signaling pathway
prob04917  Prolactin signaling pathway
prob04919  Thyroid hormone signaling pathway
prob04921  Oxytocin signaling pathway
prob04926  Relaxin signaling pathway
prob05100  Bacterial invasion of epithelial cells
prob05135  Yersinia infection
prob05152  Tuberculosis
prob05161  Hepatitis B
prob05163  Human cytomegalovirus infection
prob05167  Kaposi sarcoma-associated herpesvirus infection
prob05168  Herpes simplex virus 1 infection
prob05203  Viral carcinogenesis
prob05205  Proteoglycans in cancer
prob05207  Chemical carcinogenesis - receptor activation
prob05208  Chemical carcinogenesis - reactive oxygen species
prob05219  Bladder cancer
prob05417  Lipid and atherosclerosis
prob05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:prob00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    127224653 (Src)
   04015 Rap1 signaling pathway
    127224653 (Src)
   04370 VEGF signaling pathway
    127224653 (Src)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    127224653 (Src)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    127224653 (Src)
   04137 Mitophagy - animal
    127224653 (Src)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    127224653 (Src)
   04520 Adherens junction
    127224653 (Src)
   04530 Tight junction
    127224653 (Src)
   04540 Gap junction
    127224653 (Src)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    127224653 (Src)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    127224653 (Src)
   04613 Neutrophil extracellular trap formation
    127224653 (Src)
   04625 C-type lectin receptor signaling pathway
    127224653 (Src)
   04062 Chemokine signaling pathway
    127224653 (Src)
  09152 Endocrine system
   04912 GnRH signaling pathway
    127224653 (Src)
   04915 Estrogen signaling pathway
    127224653 (Src)
   04917 Prolactin signaling pathway
    127224653 (Src)
   04921 Oxytocin signaling pathway
    127224653 (Src)
   04926 Relaxin signaling pathway
    127224653 (Src)
   04919 Thyroid hormone signaling pathway
    127224653 (Src)
  09156 Nervous system
   04727 GABAergic synapse
    127224653 (Src)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    127224653 (Src)
  09158 Development and regeneration
   04360 Axon guidance
    127224653 (Src)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    127224653 (Src)
   05207 Chemical carcinogenesis - receptor activation
    127224653 (Src)
   05208 Chemical carcinogenesis - reactive oxygen species
    127224653 (Src)
   05203 Viral carcinogenesis
    127224653 (Src)
  09162 Cancer: specific types
   05219 Bladder cancer
    127224653 (Src)
  09172 Infectious disease: viral
   05161 Hepatitis B
    127224653 (Src)
   05168 Herpes simplex virus 1 infection
    127224653 (Src)
   05163 Human cytomegalovirus infection
    127224653 (Src)
   05167 Kaposi sarcoma-associated herpesvirus infection
    127224653 (Src)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    127224653 (Src)
   05152 Tuberculosis
    127224653 (Src)
   05100 Bacterial invasion of epithelial cells
    127224653 (Src)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127224653 (Src)
   05418 Fluid shear stress and atherosclerosis
    127224653 (Src)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    127224653 (Src)
   01522 Endocrine resistance
    127224653 (Src)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:prob01001]
    127224653 (Src)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:prob04131]
    127224653 (Src)
Enzymes [BR:prob01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     127224653 (Src)
Protein kinases [BR:prob01001]
 Non-receptor tyrosine kinases
  SRC family
   127224653 (Src)
Membrane trafficking [BR:prob04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    127224653 (Src)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    127224653 (Src)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    127224653 (Src)
  Macropinocytosis
   Kinases
    127224653 (Src)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 127224653
NCBI-ProteinID: XP_051043714
LinkDB
Position
Unknown
AA seq 553 aa
MGSNKSKPKDASQRRRSLEPAENVHGSGGAFPASQTPSKPASADGHRGPSAAFGATTAAE
SKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq 1662 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaagatgccagccagaggcgccgcagcctggagccc
gccgagaacgtgcacgggtcagggggagccttcccggcttcgcagacaccgagcaagccc
gcctccgccgacggccaccgagggcccagcgccgcctttggggccaccacggccgcagag
tccaagctcttcggaggcttcaactcctcggacacggtcacctctccgcagagggccggg
cctctggcaggtggggtgaccacctttgtggccctctatgactatgagtcaaggacagag
actgacctgtccttcaagaaaggagagcggctgcagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcacactcgctgagcacgggacagaccggttacatccccagcaactatgtggcaccctcg
gactccatccaggctgaggagtggtactttggcaagatcactaggcgggagtctgagcgg
ctactgctcaatgccgagaacccaagagggaccttccttgtgagggagagtgagaccaca
aaaggtgcctactgcctctctgtatccgacttcgacaatgcaaagggcctcaatgtgaaa
cactacaagatccgcaaactggacagcggaggcttctacatcacctcccgcacccagttc
aacagcctgcagcagctagtggcctactactccaaacatgctgatggcctgtgccaccgc
ctcactaccgtgtgccccacgtccaagcctcagacccagggcctggccaaggatgcctgg
gagatcccccgggagtccctgcgtctggaggtcaagttgggccagggctgcttcggagag
gtgtggatggggacctggaatggcaccacaagggtcgccatcaaaaccctgaagccaggc
accatgtctccagaggccttcttgcaggaggcccaagtcatgaagaaactgaggcatgag
aaactggtgcagctgtatgccgtggtgtccgaggaacccatttacatcgtgacagagtac
atgagcaaggggagtctgctggactttctcaagggggaaacgggcaaatacctgcggcta
ccccagctggtggacatggctgctcagatcgcttccggtatggcctatgtggagcggatg
aactacgtgcaccgggatctccgagccgccaatatcctggttggggagaatctggtgtgt
aaggtggctgactttggtctggcccggctcatagaagacaatgaatacacagcccggcaa
ggtgccaaattccccatcaagtggactgctcccgaagctgctctgtatggcaggttcacc
atcaagtctgatgtgtggtcctttgggatcctgctgactgagctcaccactaagggacgg
gtgccctaccctgggatggtgaaccgtgaggtgctggaccaggtggagcggggctaccgg
atgccttgtccccccgagtgccctgagtccctgcatgacctcatgtgccagtgctggcgg
aaggagcctgaggagcgacccaccttcgagtacctgcaggccttcctggaggactacttc
acctctaccgagccgcagtaccagcccggggagaacctatag

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