Phodopus roborovskii (desert hamster): 127224882 Help Entry 127224882         CDS       T08852                                  Symbol Tlr4 Name (RefSeq) toll-like receptor 4   KO K10160   toll-like receptor 4 Organism prob  Phodopus roborovskii (desert hamster) Pathway prob04064   NF-kappa B signaling pathway prob04066   HIF-1 signaling pathway prob04145   Phagosome prob04151   PI3K-Akt signaling pathway prob04217   Necroptosis prob04613   Neutrophil extracellular trap formation prob04620   Toll-like receptor signaling pathway prob04621   NOD-like receptor signaling pathway prob04936   Alcoholic liver disease prob05132   Salmonella infection prob05133   Pertussis prob05134   Legionellosis prob05135   Yersinia infection prob05140   Leishmaniasis prob05142   Chagas disease prob05144   Malaria prob05145   Toxoplasmosis prob05146   Amoebiasis prob05152   Tuberculosis prob05161   Hepatitis B prob05162   Measles prob05164   Influenza A prob05170   Human immunodeficiency virus 1 infection prob05171   Coronavirus disease - COVID-19 prob05205   Proteoglycans in cancer prob05235   PD-L1 expression and PD-1 checkpoint pathway in cancer prob05321   Inflammatory bowel disease prob05323   Rheumatoid arthritis prob05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:prob00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     127224882 (Tlr4)    04066 HIF-1 signaling pathway     127224882 (Tlr4)    04151 PI3K-Akt signaling pathway     127224882 (Tlr4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     127224882 (Tlr4)   09143 Cell growth and death    04217 Necroptosis     127224882 (Tlr4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     127224882 (Tlr4)    04620 Toll-like receptor signaling pathway     127224882 (Tlr4)    04621 NOD-like receptor signaling pathway     127224882 (Tlr4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     127224882 (Tlr4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     127224882 (Tlr4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     127224882 (Tlr4)    05161 Hepatitis B     127224882 (Tlr4)    05171 Coronavirus disease - COVID-19     127224882 (Tlr4)    05164 Influenza A     127224882 (Tlr4)    05162 Measles     127224882 (Tlr4)   09171 Infectious disease: bacterial    05132 Salmonella infection     127224882 (Tlr4)    05135 Yersinia infection     127224882 (Tlr4)    05133 Pertussis     127224882 (Tlr4)    05134 Legionellosis     127224882 (Tlr4)    05152 Tuberculosis     127224882 (Tlr4)   09174 Infectious disease: parasitic    05146 Amoebiasis     127224882 (Tlr4)    05144 Malaria     127224882 (Tlr4)    05145 Toxoplasmosis     127224882 (Tlr4)    05140 Leishmaniasis     127224882 (Tlr4)    05142 Chagas disease     127224882 (Tlr4)   09163 Immune disease    05323 Rheumatoid arthritis     127224882 (Tlr4)    05321 Inflammatory bowel disease     127224882 (Tlr4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     127224882 (Tlr4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     127224882 (Tlr4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:prob04131]     127224882 (Tlr4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:prob04054]     127224882 (Tlr4)    04090 CD molecules [BR:prob04090]     127224882 (Tlr4)    00536 Glycosaminoglycan binding proteins [BR:prob00536]     127224882 (Tlr4) Membrane trafficking [BR:prob04131]  Endocytosis   Phagocytosis    Toll-like receptors     127224882 (Tlr4) Pattern recognition receptors [BR:prob04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    127224882 (Tlr4) CD molecules [BR:prob04090]  Proteins   127224882 (Tlr4) Glycosaminoglycan binding proteins [BR:prob00536]  Hyaluronan   Cell surface receptors    127224882 (Tlr4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 TIR_2 LRR_Zer-1 LRR_9 LRR_NXF1-5 ThsB_TIR Motif Other DBs NCBI-GeneID:  127224882 NCBI-ProteinID:  XP_051043988 UniProt:  A0AAU9ZE72 LinkDB All DBs Position Unknown AA seq 837 aa AA seqDB search MMPSFCLPGTLMMALFFSLRPESLDPCVEVDPNISYQCMDQNLNKIPENIPSSVKYLDLS FNPLRTLGSHSFSNFPELQLLDLSRCEIETIEDKAYQGLHQLSTLILTGNPIHNLSQRSF SGLPSLQNLVVVEIKLTSLDSLPIGHLITLKKLNVAHNLIHSFKLPEYFSNLTNLEHLDL SNNYIQRIYYTDLQTLRENPQLNLSLELSLNPIDFIQPGAFLGIKLHEMTLRSNFNSTNV MKTCIQNLDGLQVHRLILGEFKNERKVEMFDRSVMEGLCKVTIDEFRLTYADEFSNDITD FYCLANVSAISLANVYVKHLEDIPKYFKWQTLAVIRCELKQFPPLELPFLKKLIFATNRG ATSFEEVNLPNLTFLDLSGNGMSFRGCCSYSALGTRSLKHLDLSFNGVISMNSNFMGLEQ LEYLDFQHSTLKKATEFSMFLPLEKLLYLDISYTNTKIDFNGIFFGLTSLNTLKLAGNSF KDNTLSNVFTNTTNLTFLDISKCQLQQVSSGVFDTLHRLELLNMSHNNLLILEPFYYKQL HSLKTLDYSFNHIETSKGILQHFPKNLTFLNLSHNSFACICEHQNFLQWVKDQRLFLVNT EQMTCATPVEMKGSLVLDFRNATCYMQKTIISVTVISVLVVSTIAFLVYKFYFHLILIAG CKKYSRGESIYDAFVIYSSRDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANII QEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSHSGIIFIVLEKVEKSLLKQQV ELYRLLSRNTYLEWEDNALGRHIFWRRLKKALLDGRAWDPEGAAETENNQQEATTSI NT seq 2514 nt NT seq  +upstreamnt  +downstreamnt atgatgccttctttctgcctgcctgggacactgatgatggctttgttcttctccctgaga cctgaaagcttggatccctgtgtggaggtggatcctaacattagctaccaatgcatggat caaaatctcaacaaaatcccggaaaacattccctcttcagtcaagtacttagatctgagc ttcaaccccctgaggacattgggaagccatagcttctctaattttccagaactccagttg ctggatttatccaggtgtgaaattgagacaattgaagacaaggcatatcagggtttacac cagctctcaaccttgatactgacaggaaaccctatccacaatttatcccagagaagtttt tctggactaccaagtttacagaatctagtggttgtggaaataaaactgacttctctagac agcttacctattggacaccttataactttaaagaaactcaatgtggctcacaatcttata cattcctttaagctacctgaatatttttccaatctgactaacctagaacacttggacctt tctaataactatattcaaagaatttactacacagacttacagactttacgtgaaaatccc cagctcaatctctctctagagttgtccttgaacccaattgactttattcaacctggagcc tttctaggaattaagctccatgaaatgactctaagaagtaattttaatagcacaaatgta atgaaaacttgcattcaaaacctggatggtttacaagtccatcggctgatcttgggagaa tttaaaaatgaaaggaaggtggaaatgtttgaccgctctgtcatggaaggactgtgcaag gtgaccattgatgagttccggctaacgtatgcagatgagttttctaatgatatcaccgac ttctattgcttggcaaatgtttctgcaatctctctggcaaatgtgtatgtgaagcaccta gaagacattcctaaatatttcaaatggcaaaccttagcagtcattagatgtgaactcaaa caattcccacctctggaactcccctttcttaaaaagttgatttttgctaccaacagaggg gctaccagttttgaggaagtgaatctgccaaacctcacttttttagatctcagtggaaat ggtatgagttttaggggttgctgttcttattctgctttgggaacaagaagcctgaaacac ttagacctcagcttcaatggtgtcatcagcatgaattcaaacttcatgggtttagaacag ctggaatacttggattttcaacattccactttaaaaaaggccacagaattctcaatgttc ttaccccttgaaaaacttctttatcttgacatctcttatactaacaccaaaattgacttc aatggcatattttttggtttgaccagtctcaacaccttaaaattggctggcaattctttc aaagacaacacactttcaaatgtctttacaaatactacaaacttgacattcctggatatt tctaaatgccaactgcaacaagtatcttcgggggtatttgacacactccatagacttgag ttactaaatatgagtcacaacaatctacttattttggaaccattctattataaacagctg cactctctcaagactcttgattacagtttcaatcacatagaaacatccaaaggaatactt caacattttccaaagaatctaaccttcttaaatctttctcataattcctttgcttgtata tgtgagcatcagaacttcctgcagtgggtcaaggaccagaggctgtttctagtgaacact gaacaaatgacatgtgcaacacctgtagagatgaagggctccctggtattggactttagg aatgccacctgttatatgcagaagaccatcattagtgtgacagtgatcagtgtgcttgtg gtatccaccatagcatttctggtctacaaattctattttcacctgatacttattgctggt tgtaaaaagtacagtagaggtgagagcatctatgatgcctttgtcatctactccagccgg gatgaagactgggtgagaaatgagttggtaaagaatttagaagaaggggtgccccccttt cagctgtgcctccactacagagattttattcctggtgtggccatcgctgccaacatcatc caggaaggcttccacaagagccggaaggttattgttgtggtgtctagacactttatccag agccgctggtgtatctttgaatatgagattgctcagacatggcagtttctgagtagtcac tctggcatcatcttcattgtcctggagaaggtggagaagtccctactgaagcaacaagta gagttgtatcgtcttctcagcaggaacacctacctagagtgggaggacaatgctctggga aggcacatcttttggagaaggctcaaaaaagctcttttggatggaagagcctgggatcca gagggagcagcagagacagaaaacaatcaacaagaagcaacaacttccatctga

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