Phodopus roborovskii (desert hamster): 127226412
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Entry
127226412 CDS
T08852
Symbol
Atic
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC isoform X1
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob00230
Purine metabolism
prob00670
One carbon pool by folate
prob01100
Metabolic pathways
prob01523
Antifolate resistance
Module
prob_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
127226412 (Atic)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
127226412 (Atic)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
127226412 (Atic)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
prob04147
]
127226412 (Atic)
Enzymes [BR:
prob01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
127226412 (Atic)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
127226412 (Atic)
Exosome [BR:
prob04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
127226412 (Atic)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-GeneID:
127226412
NCBI-ProteinID:
XP_051046377
LinkDB
All DBs
Position
Unknown
AA seq
610 aa
AA seq
DB search
MSPPQIRENALQKPANNEKMPSVSALFSVSDKTGLVEFARNLASLGLSLVASGGTAKALR
DAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACN
LYPFVKTVASPDVTVEAAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVTVAAEMQNSD
NKDTSLETRRHLALKAFTHTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTL
KPKLPITVLNGAPGFINLCDALNAWQLVKELREAVDIPAAASFKHVSPAGAAVGIPLSED
EARVCMVYDLYPTLTPVATAYARARGADRMSSFGDFIALSDVCDVPTAKIISREVSDGIV
APGYEEEALKILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLRLSQKRNNGVIDKSLFSN
IVTKNKDLPESALRDLIVATVAVKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKA
NSWWLRHHPRVLSMKFKSGVKRAEISNAIDQYVTDTIGEGDDLVKWKALFEEVPELLTET
EKKEWVDKLRDVSVSSDAFFPFRDNVDRAKRSGVAYIVAPSGSAADKVVIEACDELGIVL
AHTDLRLFHH
NT seq
1833 nt
NT seq
+upstream
nt +downstream
nt
atgtcccctccccagatccgggagaacgctttgcaaaagcccgcgaataatgagaaaatg
ccttctgtttcagccctgttcagtgtgtctgacaaaactggcctagtggaatttgccagg
aacctcgcatctcttggtttgagtctagtcgcttccggaggcacggcaaaagcgctcagg
gatgctggcctggcagtcagagatgtgtctgagctaacaggttttcccgaaatgttaggg
gggcgtgtgaaaaccttgcatcctgctgtccacgctggaatcttggcgcgaaatattcca
gaagataatgctgacatggccagacttgatttcaaccttataagagttgttgcctgtaac
ctgtacccctttgtgaagaccgtggcttctccagatgtgactgttgaggcagctgttgag
cagattgatattggcggagtgaccttactgagagctgcagccaaaaaccacgctcgagtg
acagttgtgtgtgaaccagaagactatgtgacggtggcagcagagatgcagaactctgat
aataaggacacctccctggagaccaggcgccacttggccttgaaggcatttactcatact
gcacaatatgatgaagcgatttcagattacttcagaaagcaatacagtaaaggaatttcc
cagatgcccttgcggtatgggatgaacccacatcagacgcctgctcagctttatacgctg
aagcccaagcttcccatcacggttctcaatggagcccctggattcataaacttgtgtgat
gctttgaatgcctggcagctggtgaaggagctcagggaagcagtggacatcccagctgcg
gcatctttcaaacacgtcagcccagcaggtgctgctgtcgggattccactcagtgaagac
gaggccagggtgtgcatggtctacgacctctatccgaccctcacgccagtggccactgca
tatgccagagcaagaggggccgacaggatgtcttcatttggtgattttattgcattatct
gatgtttgtgatgtcccaactgcaaaaattatctccagagaagtgtcggatggtattgtt
gccccaggatatgaagaagaagccttgaaaatactttctaaaaagaaaaatggaaactac
tgtgttcttcagatggaccagtcctacaaaccggatgaaaatgaagttcgaacactcttt
ggtcttcgtttaagccagaagagaaataatggagtcattgacaagtcattatttagcaat
attgtcaccaagaataaagatctgccggagtctgccctcagagacctcattgtagccact
gtcgctgttaagtacactcagtccaactccgtgtgctacgccaaggatggacaggttatt
ggcatcggagcaggacagcagtctcggatacactgcacacgccttgcaggtgataaggca
aactcgtggtggctccgacaccatccacgagtgctctccatgaagtttaaaagcggggtg
aagagagcagaaatctccaacgccattgatcagtatgtgacagacaccattggtgaggga
gatgacctggtgaagtggaaggcactgttcgaggaagtccccgagttactcactgagaca
gagaagaaggaatgggtcgacaaactgagagatgtttcggtcagctctgatgccttcttt
cccttcagggacaacgtggaccgagccaaaaggagtggtgtggcctacattgtcgctccc
tctggatccgctgcagacaaggttgtgatcgaggcctgtgatgaactggggatcgtcttg
gctcacacggatctccggctcttccaccactga
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