Phodopus roborovskii (desert hamster): 127227519
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Entry
127227519 CDS
T08852
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob00230
Purine metabolism
prob00670
One carbon pool by folate
prob01100
Metabolic pathways
prob01523
Antifolate resistance
Module
prob_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
127227519 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
127227519 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
127227519 (Gart)
Enzymes [BR:
prob01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
127227519 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
127227519 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
127227519 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_4
Dala_Dala_lig_C
ATP-grasp_2
ATP-grasp_3
RimK
LUD_dom
Motif
Other DBs
NCBI-GeneID:
127227519
NCBI-ProteinID:
XP_051047852
UniProt:
A0AAU9ZMM4
LinkDB
All DBs
Position
Unknown
AA seq
1009 aa
AA seq
DB search
MSARVLVIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSGKISNAAVSIADHAVLAQ
FCRDERIEFVVVGPEAPLAAGIVEDLTSAGVRCFGPTAQAAQLESSKKFAKEFMDRHGIP
TAQWGAFTKAEDACSFIMSANFPALVVKASGLAAGKGVIVAKNQEEACKAVQEIMQEKSF
GAAGETVVVEECLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDQGPNTGGMGAYCPAP
QVPKELLLTIKSTILQRAVDGMQEEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYELIQSTLDGQLSTSLPVWLENHTAVTVVMASKGYPGAYAKGVEITGFPEA
QALGLQVFHAGTALKDGTVVTSGGRVLTVTAVQEDLVSALEEAKRGLAAMQFEGAVYRKD
IGFRAVAFLQRPRGLTYKESGVDIAAGNMLVKKIQPLAKATSRPGCNVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHATIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLTTTEAVVAGIAEACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
QLERIAEGDVVIGVASSGLHSNGFSLVRKVVARSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPIIRSGCVKALAHITGGGLLENIPRVLPRKLGVDLDACAWRIPRVFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKDQTDQILHDIRQRQEEAWVIGRVVACPEDSPRVRVKN
LIEAMQINGSGVSNGFLRSNFPAQQKSRVAVLISGTGSNLQALIDSTRDPKSSTHIVVVI
SNKAGVAGLDKAEKAGIPTRVINHKLYKNRVEFDNAVDHVLEEFSVDIVCLAGFMRILSG
PFVKKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVMITGCTVHFVAEDVDAGQIILQEAV
PVKRGDTVATLSERVKLAEHKIFPAALQLVASGAVLLGEDGKIHWAREQ
NT seq
3030 nt
NT seq
+upstream
nt +downstream
nt
atgtcagcccgagttcttgtgatcggcagtggagggagggaacatacgctggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaatgcaggcactgcc
tgttctggaaagatctcaaatgctgctgtctccatcgctgaccacgctgtccttgctcag
ttctgcagagatgaaaggattgagtttgtggttgtaggaccggaggcccctctggctgca
gggattgtagaggacctgacctctgcaggtgtacgatgctttggccccacagcacaagca
gctcagttagagtccagtaaaaagtttgccaaagagtttatggaccgccatggaatccca
actgcacagtggggagcattcaccaaggctgaagacgcctgcagctttatcatgagcgca
aactttcctgctttggttgtgaaggccagtggccttgcagcggggaaaggagtgattgtt
gcaaagaatcaagaggaggcctgcaaagctgtacaggagatcatgcaagaaaaatctttt
ggagcagctggagaaacggttgttgtggaagagtgtctggatggggaagaagtatcttgt
ctgtgtttcactgatgggaagacagtggccccaatgcccccagcacaggaccataagcga
ctgctggatggagaccagggccccaacaccggggggatgggagcctactgcccagcaccc
caggttcctaaagagttgttgctaaccattaaaagcactattcttcagagagcagtagat
ggcatgcaggaggagggtgtgccttacacaggaattctctacgctggcataatgctgacc
aaagatggcccaaaagttttggagtttaattgccgttttggtgacccagaatgccaagta
atccttccgcttcttaaaagtgacctctatgagttgattcagtccaccttagatggccag
ctgagtacatctctgcctgtgtggctagaaaaccacactgccgtaactgttgtcatggcg
agtaaagggtaccctggagcctacgccaagggtgtggaaataacagggtttccggaggcc
caggcgttaggactgcaggtattccatgccggcactgctcttaaagatggcacagtggtg
accagcgggggcagggtcctcacagtcacggccgtccaggaagaccttgtgtcagccctc
gaggaggccaagagaggactcgccgctatgcagtttgagggagcagtttataggaaggac
attggcttccgtgcagtagccttcctccagcggcccaggggcctgacttacaaggaatct
ggagtagacattgcagctggaaatatgctggttaagaaaattcagcctttagcaaaagcc
acctccagaccaggctgcaatgttgaccttggaggctttgctggtctttttgatttgaaa
gcagctggcttcaaagatcctcttctggcttctggaacagatggtgttgggactaaactg
aagatcgcccagctgtgcaacaagcatgccaccattggtcaggatctggttgccatgtgt
gtaaatgacatcctagcacaaggagccgagcctctcttcttccttgattacttttcctgt
ggaaaacttgacctcactacgactgaagctgtcgttgctgggattgctgaagcctgcaga
caagctggctgtgctctgctgggtggggagaccgcagagatgcccgacatgtaccctcct
ggcgagtatgacctggctgggtttgctgtgggtgctatggagagggatcagaaactccct
cagctagaaaggatcgctgaaggggatgttgtcatcggagtagcctcatctggtcttcac
agcaatgggtttagcctcgtgaggaaggtcgttgcgaggtcttccctccagtactcctct
ccagcgcccgatggatgtggcgaccagacattaggggacttacttctaactccgaccagg
atctacagccattcactgttgcctatcatacgttcaggatgtgtcaaagccttggctcac
attactggaggtggactgctagaaaacatccccagagtcctccctcggaagcttggggta
gatttagatgcctgcgcctggaggatccccagggtcttctcatggttacagcaggaagga
cagctctctgaagaagaaatggccagaaccttcaactgtggggttggagctgccctggtg
gtgtctaaggaccagacagaccaaattctgcatgacattcggcagcgccaggaggaagcc
tgggtgataggcagggtcgtggcctgtcctgaagattcccctcgtgtcagagtgaagaat
ctgattgaagccatgcaaataaatgggtcaggggtgtcaaatggcttcctgagaagtaat
ttccctgcccagcagaagtcaagagtggctgtgttaatatctgggacaggatcgaacctc
caagcactcatagacagcactcgagatccaaagagctccacacacattgtggttgtcatc
tccaacaaagctggtgtcgctggcctcgacaaagcagaaaaggctgggattcccaccaga
gtaattaatcataaattatataaaaatcgtgttgaatttgacaatgctgttgaccatgtc
ctggaagagttctctgtagacatagtctgccttgcgggattcatgagaattctctctggc
ccttttgtcaaaaaatgggatgggaaaatgctcaacatccacccatccttgctcccttcc
tttaagggctcgaatgctcatgagcaagtcctggaggctggggtcatgatcaccggctgc
actgtacacttcgtagctgaagacgtagacgcgggacagatcatcctccaagaagctgtc
cctgtgaagaggggtgacactgttgcaactttgtctgaaagagtcaaactagcagagcac
aaaatcttccctgcagccctccagctggtggccagtggggctgtgctccttggagaagac
ggcaagatccactgggccagagaacagtga
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