Phodopus roborovskii (desert hamster): 127230359 Help Entry 127230359         CDS       T08852                                  Symbol Adcy4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism prob  Phodopus roborovskii (desert hamster) Pathway prob00230   Purine metabolism prob01100   Metabolic pathways prob01522   Endocrine resistance prob04015   Rap1 signaling pathway prob04020   Calcium signaling pathway prob04022   cGMP-PKG signaling pathway prob04024   cAMP signaling pathway prob04062   Chemokine signaling pathway prob04072   Phospholipase D signaling pathway prob04081   Hormone signaling prob04082   Neuroactive ligand signaling prob04114   Oocyte meiosis prob04211   Longevity regulating pathway prob04213   Longevity regulating pathway - multiple species prob04261   Adrenergic signaling in cardiomyocytes prob04270   Vascular smooth muscle contraction prob04371   Apelin signaling pathway prob04540   Gap junction prob04611   Platelet activation prob04713   Circadian entrainment prob04714   Thermogenesis prob04723   Retrograde endocannabinoid signaling prob04724   Glutamatergic synapse prob04725   Cholinergic synapse prob04727   GABAergic synapse prob04742   Taste transduction prob04750   Inflammatory mediator regulation of TRP channels prob04911   Insulin secretion prob04912   GnRH signaling pathway prob04913   Ovarian steroidogenesis prob04914   Progesterone-mediated oocyte maturation prob04915   Estrogen signaling pathway prob04916   Melanogenesis prob04918   Thyroid hormone synthesis prob04921   Oxytocin signaling pathway prob04923   Regulation of lipolysis in adipocytes prob04925   Aldosterone synthesis and secretion prob04926   Relaxin signaling pathway prob04927   Cortisol synthesis and secretion prob04928   Parathyroid hormone synthesis, secretion and action prob04934   Cushing syndrome prob04935   Growth hormone synthesis, secretion and action prob04970   Salivary secretion prob04971   Gastric acid secretion prob04972   Pancreatic secretion prob04976   Bile secretion prob05032   Morphine addiction prob05163   Human cytomegalovirus infection prob05166   Human T-cell leukemia virus 1 infection prob05200   Pathways in cancer prob05207   Chemical carcinogenesis - receptor activation prob05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:prob00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     127230359 (Adcy4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     127230359 (Adcy4)    04371 Apelin signaling pathway     127230359 (Adcy4)    04020 Calcium signaling pathway     127230359 (Adcy4)    04072 Phospholipase D signaling pathway     127230359 (Adcy4)    04024 cAMP signaling pathway     127230359 (Adcy4)    04022 cGMP-PKG signaling pathway     127230359 (Adcy4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     127230359 (Adcy4)    04081 Hormone signaling     127230359 (Adcy4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     127230359 (Adcy4)   09144 Cellular community - eukaryotes    04540 Gap junction     127230359 (Adcy4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     127230359 (Adcy4)    04062 Chemokine signaling pathway     127230359 (Adcy4)   09152 Endocrine system    04911 Insulin secretion     127230359 (Adcy4)    04923 Regulation of lipolysis in adipocytes     127230359 (Adcy4)    04912 GnRH signaling pathway     127230359 (Adcy4)    04913 Ovarian steroidogenesis     127230359 (Adcy4)    04915 Estrogen signaling pathway     127230359 (Adcy4)    04914 Progesterone-mediated oocyte maturation     127230359 (Adcy4)    04921 Oxytocin signaling pathway     127230359 (Adcy4)    04926 Relaxin signaling pathway     127230359 (Adcy4)    04935 Growth hormone synthesis, secretion and action     127230359 (Adcy4)    04918 Thyroid hormone synthesis     127230359 (Adcy4)    04928 Parathyroid hormone synthesis, secretion and action     127230359 (Adcy4)    04916 Melanogenesis     127230359 (Adcy4)    04925 Aldosterone synthesis and secretion     127230359 (Adcy4)    04927 Cortisol synthesis and secretion     127230359 (Adcy4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     127230359 (Adcy4)    04270 Vascular smooth muscle contraction     127230359 (Adcy4)   09154 Digestive system    04970 Salivary secretion     127230359 (Adcy4)    04971 Gastric acid secretion     127230359 (Adcy4)    04972 Pancreatic secretion     127230359 (Adcy4)    04976 Bile secretion     127230359 (Adcy4)   09156 Nervous system    04724 Glutamatergic synapse     127230359 (Adcy4)    04727 GABAergic synapse     127230359 (Adcy4)    04725 Cholinergic synapse     127230359 (Adcy4)    04723 Retrograde endocannabinoid signaling     127230359 (Adcy4)   09157 Sensory system    04742 Taste transduction     127230359 (Adcy4)    04750 Inflammatory mediator regulation of TRP channels     127230359 (Adcy4)   09149 Aging    04211 Longevity regulating pathway     127230359 (Adcy4)    04213 Longevity regulating pathway - multiple species     127230359 (Adcy4)   09159 Environmental adaptation    04713 Circadian entrainment     127230359 (Adcy4)    04714 Thermogenesis     127230359 (Adcy4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     127230359 (Adcy4)    05207 Chemical carcinogenesis - receptor activation     127230359 (Adcy4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     127230359 (Adcy4)    05163 Human cytomegalovirus infection     127230359 (Adcy4)   09165 Substance dependence    05032 Morphine addiction     127230359 (Adcy4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     127230359 (Adcy4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     127230359 (Adcy4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     127230359 (Adcy4) Enzymes [BR:prob01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      127230359 (Adcy4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  127230359 NCBI-ProteinID:  XP_051051598 UniProt:  A0AAU9ZPY1 LinkDB All DBs Position Unknown AA seq 1072 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCTLVALPAVAWASGRELTSDPS FLTMVLCALGGFSLLLGLASREQRLQRWTRPLSGLIWAALLALGHGFLFTGGVVSAWDQV SFFLFIIFTVYSMLPLGMRDAAVAGLTSSLSHLLVLGLYLGWQPDSQRNLLPQLAANAVL FLCGNVVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAVNCVRMGLDMCRAIRKLRVATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG TYAVENADMEHRDTYLRELGEPTYLVIDPRAEEEDEKGTATGLLSSLEGHKMRPSLLMTR YLESWGAAKPFAHLSHMDSPVSTSTPLPEKAFSPQWSLDRSRTPRGLDDELDTGDAKFFQ VIEQLNSQKQWKQSKDFNLLTLYFRKKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQM LVTNRPPALATTYSITFLLFLLLLFICFSEHLTKCIQKGPKVLRWLPALSVLVTTRPGLR VALGTVTIFLVFTMAIASLLFLPVSSDCLFLASNASSAAFNTSWELPGSLPLISIPYSMH CCVLGFLSCSVFLHMSFELKLLLLLLWLVASCSFFLHSHAWLSDCLIAHLYGSPLDSRPG VLKEPKLMGAIYFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLE NVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLN EIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDTQQDADRSCSHLGTMVEFA VALGSKLDIINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVL GKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGSPSAP NT seq 3219 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagcccccggccgccccccagcgaagatctcttctatgagacctac tacagcctgagccaacagtacccactgctactactgcttctggtcatcgtgctctgcacg ctcgtggcactgccagccgtcgcctgggccagcggcagggagctgacctcagacccaagc ttcctgacaatggtgctgtgtgctttgggtggcttctctctgctgttggggctggcttcc cgagagcagcgactgcagcgctggacacggcctctttctggcctcatatgggctgcactg ctggctctaggccatggattcctgttcactgggggtgtggtgagcgcctgggaccaggtg tcatttttcctcttcatcatcttcactgtgtactccatgttgcccctgggcatgcgggat gctgctgttgcaggcctcacatcatcactctcgcatctgctggtccttggactgtacctt gggtggcagcctgactcacagaggaatctgctaccacagttggcagcaaatgcggtgttg tttctctgtgggaatgtggtgggagcataccacaaggccttgatggagcgagcattgcgt gccaccttcagagaggctctcagctctcttcactcacgccggaggttggacactgagaaa aagcatcaggagcacctccttttgtccatccttcctgcctacctggcccgagagatgaaa gcggagatcatggcacggctgcaggctgggcagggatcacggccagagaacacgaacaac tttcacagcctgtatgtcaagagacaccaaggagtcagtgtgctgtatgctgacatcgtg ggcttcacgcggctggccagcgagtgttcccctaaagagctggtgctcatgctcaatgag ctctttggcaagttcgaccagattgccaaggagcacgaatgcatgcggatcaagatcctg ggggactgttactactgtgtctccgggctgccactctcactgccagaccacgccgtcaac tgcgtgcgcatgggactggacatgtgccgggccatcaggaaacttcgggtagccactggt gtggacatcaacatgcgtgtgggtgtgcactcgggcagcgtgctctgtggagtcatcggg ctacagaagtggcagtatgatgtctggtcccatgatgtcacattggccaaccacatggaa gctggcggtgtgccaggacgcgtgcacatcacaggggctactctggccctgttggcaggg acctatgctgtggagaacgcagacatggaacaccgagacacataccttcgggagctaggc gaacctacatacctggtcatcgatccccgggctgaggaggaagatgagaagggcactgct acagggttactgtcttctttggaggggcacaagatgcgtccatcattactgatgactcgt tacctggagtcttggggtgcagccaaaccgtttgcccacttaagccacatggacagtcct gtatcaacctccactccactcccggaaaaggccttcagcccccaatggagcctagaccgg agtcgcaccccacggggactagatgatgaactggacaccggggatgccaagttcttccag gtcatcgagcaactcaactctcagaaacagtggaagcagtcgaaagacttcaacctcctg acactgtacttcagaaagaaggagatggagaagcagtaccggctctctgcactccccgcc ttcaaatactatgcagcctgcaccttcctggtttttctgtccaacttcactatccaaatg ctggtgacaaacaggcccccagctctggccaccacctacagcatcaccttcctcctcttc cttctcctcctcttcatctgcttctcagagcacctgacgaagtgcatccagaaaggtccc aaagtgttgcgctggctgcctgcactgtctgtcctggtgactacacggccaggacttcga gtagccctgggcactgtcactatcttcctggtgttcactatggccatcgccagcctgctc ttcttgccagtgtcatcagactgccttttcctggcttccaatgcatcttctgcagctttc aacacttcctgggagctgccaggatccctgcctctcatcagtatcccatactccatgcat tgctgcgtgctgggtttcctctcctgttccgtttttctgcacatgagctttgaactgaaa ctactgctgctcctgctgtggctggtggcatcttgttccttttttctgcactcccacgcc tggctatctgactgcctcattgcccacctctatggaagccctttggactccaggccaggg gtgctgaaggaacccaaactgatgggagccatctacttcttcatcttcttcttcacgctc cttgtcctggctcggcagaatgagtattactgccgcctggacttcctgtggaagaagaag ctgaggcaggagcgagaggagactgagacaatggagaatctaactcggctcctcctggaa aatgtgctccccgcacatgtggccccccagttcatcggccagaaccgacgcaatgaggac ctctaccaccagtcctacgaatgtgtttgtgtcctctttgcatctgtcccagactttaaa gagttctactctgaatctaacatcaaccatgaaggactggagtgtctgcggctgctcaat gagataattgctgattttgatgagctgctctccaagccaaagttcagtggagtagagaag atcaaaactattggcagcacctacatggcagccacgggcttgaatgccacctcaggacag gacacgcagcaggatgctgatcgaagctgcagccatctgggcaccatggtagaatttgca gtggccctggggtctaagctggatatcatcaacaagcactcattcaacaacttccgcctg cgtgtggggttgaaccacggaccagtcgtagcaggagtgattggggcacaaaagccacaa tatgacatctgggggaacacagtgaatgtggccagccgcatggagagtacaggggttctt ggcaagatccaagtgactgaggagacagctagagccctgcaatccctgggttatacatgc tacagccggggtgtcatcaaggtcaaaggcaaagggcaactttgtacctacttcctgaac acagacctgacaagaactggatctccctcagccccctag

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