Phodopus roborovskii (desert hamster): 127230645
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Entry
127230645 CDS
T08852
Symbol
Sos2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob01521
EGFR tyrosine kinase inhibitor resistance
prob01522
Endocrine resistance
prob04010
MAPK signaling pathway
prob04012
ErbB signaling pathway
prob04014
Ras signaling pathway
prob04062
Chemokine signaling pathway
prob04068
FoxO signaling pathway
prob04072
Phospholipase D signaling pathway
prob04150
mTOR signaling pathway
prob04151
PI3K-Akt signaling pathway
prob04510
Focal adhesion
prob04540
Gap junction
prob04630
JAK-STAT signaling pathway
prob04650
Natural killer cell mediated cytotoxicity
prob04660
T cell receptor signaling pathway
prob04662
B cell receptor signaling pathway
prob04664
Fc epsilon RI signaling pathway
prob04714
Thermogenesis
prob04722
Neurotrophin signaling pathway
prob04810
Regulation of actin cytoskeleton
prob04910
Insulin signaling pathway
prob04912
GnRH signaling pathway
prob04915
Estrogen signaling pathway
prob04917
Prolactin signaling pathway
prob04926
Relaxin signaling pathway
prob04935
Growth hormone synthesis, secretion and action
prob05034
Alcoholism
prob05160
Hepatitis C
prob05161
Hepatitis B
prob05163
Human cytomegalovirus infection
prob05165
Human papillomavirus infection
prob05200
Pathways in cancer
prob05205
Proteoglycans in cancer
prob05206
MicroRNAs in cancer
prob05207
Chemical carcinogenesis - receptor activation
prob05208
Chemical carcinogenesis - reactive oxygen species
prob05210
Colorectal cancer
prob05211
Renal cell carcinoma
prob05213
Endometrial cancer
prob05214
Glioma
prob05215
Prostate cancer
prob05220
Chronic myeloid leukemia
prob05221
Acute myeloid leukemia
prob05223
Non-small cell lung cancer
prob05224
Breast cancer
prob05225
Hepatocellular carcinoma
prob05226
Gastric cancer
prob05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
127230645 (Sos2)
04012 ErbB signaling pathway
127230645 (Sos2)
04014 Ras signaling pathway
127230645 (Sos2)
04630 JAK-STAT signaling pathway
127230645 (Sos2)
04068 FoxO signaling pathway
127230645 (Sos2)
04072 Phospholipase D signaling pathway
127230645 (Sos2)
04151 PI3K-Akt signaling pathway
127230645 (Sos2)
04150 mTOR signaling pathway
127230645 (Sos2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
127230645 (Sos2)
04540 Gap junction
127230645 (Sos2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
127230645 (Sos2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
127230645 (Sos2)
04660 T cell receptor signaling pathway
127230645 (Sos2)
04662 B cell receptor signaling pathway
127230645 (Sos2)
04664 Fc epsilon RI signaling pathway
127230645 (Sos2)
04062 Chemokine signaling pathway
127230645 (Sos2)
09152 Endocrine system
04910 Insulin signaling pathway
127230645 (Sos2)
04912 GnRH signaling pathway
127230645 (Sos2)
04915 Estrogen signaling pathway
127230645 (Sos2)
04917 Prolactin signaling pathway
127230645 (Sos2)
04926 Relaxin signaling pathway
127230645 (Sos2)
04935 Growth hormone synthesis, secretion and action
127230645 (Sos2)
09156 Nervous system
04722 Neurotrophin signaling pathway
127230645 (Sos2)
09159 Environmental adaptation
04714 Thermogenesis
127230645 (Sos2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
127230645 (Sos2)
05206 MicroRNAs in cancer
127230645 (Sos2)
05205 Proteoglycans in cancer
127230645 (Sos2)
05207 Chemical carcinogenesis - receptor activation
127230645 (Sos2)
05208 Chemical carcinogenesis - reactive oxygen species
127230645 (Sos2)
05231 Choline metabolism in cancer
127230645 (Sos2)
09162 Cancer: specific types
05210 Colorectal cancer
127230645 (Sos2)
05225 Hepatocellular carcinoma
127230645 (Sos2)
05226 Gastric cancer
127230645 (Sos2)
05214 Glioma
127230645 (Sos2)
05221 Acute myeloid leukemia
127230645 (Sos2)
05220 Chronic myeloid leukemia
127230645 (Sos2)
05211 Renal cell carcinoma
127230645 (Sos2)
05215 Prostate cancer
127230645 (Sos2)
05213 Endometrial cancer
127230645 (Sos2)
05224 Breast cancer
127230645 (Sos2)
05223 Non-small cell lung cancer
127230645 (Sos2)
09172 Infectious disease: viral
05161 Hepatitis B
127230645 (Sos2)
05160 Hepatitis C
127230645 (Sos2)
05163 Human cytomegalovirus infection
127230645 (Sos2)
05165 Human papillomavirus infection
127230645 (Sos2)
09165 Substance dependence
05034 Alcoholism
127230645 (Sos2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
127230645 (Sos2)
01522 Endocrine resistance
127230645 (Sos2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
IQ_SEC7_PH
RHG20_PH
PH_19
Motif
Other DBs
NCBI-GeneID:
127230645
NCBI-ProteinID:
XP_051051884
LinkDB
All DBs
Position
Unknown
AA seq
1333 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVPALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
DIGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRNLFKPYE
IEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQD
ILSPEFNDHFSKLMARPAVALHFQSIAEGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLK
ACSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDSVCLFYNRQLRSKHLAIKK
MNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHCQTRLP
GYSSAEYRLKEKFVMRKIQICDKEDTCEYKHAFELVSKDENSVIFVAKSAEEKNNWMAAL
ISLHYRSTLDRMLDSVLLKEENEQPLRLPSPDMYRFVVKDSEENIVFEDNLQSRSGIPII
KGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKL
ALEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSV
RGKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHP
IEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVE
AENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRIL
DEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKR
RKVAEITGEIQQYQNQPYCLRTEPDMRRFFENLNPMGILSEKEFTDYLFNKSLEIEPRNC
KQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPYKISFSRIAETELEST
VSAPTSPNTPSTPPVSASSDHSVFLDVDLNSSCGSNTIFAPVLLPQSKTFFSSCGSLHKL
SEEPLIPPPLPPRKKVDHDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGP
VHSPPPPPPREPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHPHRDPDWLRDVSTCPNSP
STPPSTPSPRVPRRSHLLSSSHSNLAHPPAPPVPPRQSSSHHLPKLPPKTYKREPSHPPL
YRLPLLGNAETPQ
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccctacgagttcttcagcgaagaaaacagcccgaaatggcgg
ggactgctggtcccggccctgcggaaggttcaggagcaagtacaccctaccctttcagcc
aatgaagagtctctttattacattgaagaactgatttttcagctgcttaataaattgtgc
atggctcagccaaggactgtgcaagatgtggaggaacgagttcagaagacctttcctcat
cctattgataaatgggcgattgctgatgcacagtctgccatcgagaaacgtaaacgaaga
aatcctcttttactgcctgtggacaaaatccatccttccttgaaggaagttttggggtac
aaagtggactaccatgtgtccctctacattgtggctgtattggagtatatctcagcagat
attttgaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcaa
gacattaaagtgtcaatgtgtgcagataaggttctgatggacatgtttgatcaggatgat
gatataggtttggtttctctctgtgaagatgaacctagctcttccggtgagctaaactat
tatgaccttgtcagaactgaaattgcagaagagagacagtatctacgggaactgaatatg
attatcaaagtattccgggaagcctttctttctgatagaaacttgttcaagccttatgaa
atcgaaaagattttcagtaacatttcagatatacatgaattgactgtgaaacttttaggt
ttaattgaagacacagtagaaatgacagatgaaagtagtcctcatccattagctggtagc
tgttttgaagatttagcagaggagcaagcgtttgacccctatgaaacattatcacaggac
attctttcaccagagtttaatgaccactttagtaaattgatggccagacctgcagttgct
ctacattttcagtccatcgctgaaggctttaaggaggccgttcgttatgtccttcctcgt
cttatgctggtgccagtgtatcattgttggcattactttgaattgttaaagcagttgaaa
gcatgtagtgaagaacaggaagacagagaatgtttgaatcaggctatcactgccctcatg
aatctccaaggcagcatggaccgaatttacaagcagcattcacctagacgccgaccaggg
gattctgtttgccttttttacaatcgtcaattaagaagcaagcacctggcgatcaaaaaa
atgaatgaaattcagaaaaacatagatgggtgggaaggcaaagatattggacagtgttgt
aatgagttcataatggaagggccattgaccagaattggcgctaaacatgaacggcacatt
tttctctttgatggcttgatgatcagctgtaaacctaatcactgccagacccgacttccg
ggttatagtagtgcggaatacagattaaaggagaagtttgtcatgaggaaaattcaaatc
tgtgataaagaagatacttgtgaatacaaacatgcttttgaattagtatccaaagatgaa
aacagtgtgatatttgttgccaaatcagctgaagagaagaataattggatggcagcgctt
atttcccttcactatcgaagtactctagatagaatgctggattctgtcttgttgaaagaa
gaaaacgagcagccgctgaggctaccaagtccagacatgtaccgctttgtggtaaaagac
tctgaggaaaacattgtgtttgaagataacttgcagagtagaagtggaatccccattatt
aaaggaggaactgtggtgaaattaattgaaaggctaacttatcatatgtatgcagatccc
aattttgttcgtacttttcttactacgtatcgttcattttgtaaaccacaggagttgcta
agcttgctgatagagcggtttgaaatcccagaaccagaacccactgaggcagacaaattg
gcactagagaaaggcgagcaaccaatcagtgcagatctgaaaagatttcgcaaggaatat
gtccaacctgtgcaactcaggatcttaaatgtctttcgccactgggttgaacatcatttt
tatgactttgaaagagacctggaattgcttgaaagactagaatccttcatttcaagtgta
agagggaaagctatgaagaaatgggtagagtccattgctaaaatcatcaagaggaagaag
caagctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaatt
gagtggcatataagtagaccaggccagtttgaaacatttgatcttatgacccttcatcca
atagaaattgcacgtcagttaacacttttggagtctgatctctacaggaaagtccaacct
tctgaacttgtagggagtgtctggaccaaagaagataaagaaataaattctccaaattta
ttaaaaatgattcgccatacaacaaacctcaccctctggtttgaaaaatgcattgtggaa
gcagaaaattttgaagagcgagtggcagtgctcagtaggataatagaaattctgcaagtg
tttcaagatttgaataatttcaatggcgtgttggaaatagtcagtgcggtcaattcagta
tcagtgtacagactagatcacacatttgaggcattgcaggaaaggaagaggagaattctg
gatgaggctgtggagttaagtcaggaccactttaagaaatacctagtgaaactgaagtca
atcaacccaccatgtgtgcctttttttggaatatacttaacaaatattctgaagactgaa
gaagggaacaatgattttctaaagaagaaagggaaagatttgatcaattttagtaagagg
aggaaagtagctgaaattactggagaaattcagcagtatcagaaccagccgtactgctta
cggactgaaccggatatgaggagattctttgaaaaccttaaccccatgggaattttatct
gaaaaagagtttacagattatttgttcaacaaatcgctagaaatagaaccccgaaactgc
aaacaaccacctcgatttcctaggaaatcaacattttccttaaaatctcctggaataagg
cctaacacaggccgacatggctctacctcaggcacgttacgaggtcatccgacacctttg
gaaagagaaccgtataagataagctttagcaggatcgctgagaccgagcttgagtcaaca
gtatcagcacccacctctccaaacacaccgtccactccccctgtgtctgcttcttcagac
cacagcgtgtttctagatgtggatctcaatagttcctgtggcagcaataccatctttgct
ccagtcctcttgccacagtcaaagactttcttcagctcatgtggaagtttacacaaattg
agtgaagagccgctgattcctcctccacttcctcctcgaaaaaaagttgatcatgatgct
tcaaattccaagggaactatgaaatctgatgatgaccctcctgctatcccaccaagacag
cctcctcctccgaaggtaaagccgagagttcctgtccccactggtgcatttgatgggcct
gtgcatagtccacctcctccacctccaagagagcctctccctgacacccccccaccagtt
cctctgcggcctccagagcattttataaactgtccgtttaatcttcagccacctccactg
ggacaccctcacagagacccagactggctcagagacgttagtacatgtccaaattcacca
agcactcctcccagcacaccctctccacgagtgccacgcagaagccatttgctcagttcc
agtcacagcaatctcgctcatcccccagctcctcctgttccgccgaggcagagctcaagc
catcacctgcccaaactgccaccaaagacctacaaacgggagccctcacacccaccactg
tacagactgcctttgcttggaaatgcagagactcctcaatga
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integrated database retrieval system
