Phodopus roborovskii (desert hamster): 127231265
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Entry
127231265 CDS
T08852
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob04217
Necroptosis
prob04380
Osteoclast differentiation
prob04620
Toll-like receptor signaling pathway
prob04621
NOD-like receptor signaling pathway
prob04630
JAK-STAT signaling pathway
prob04658
Th1 and Th2 cell differentiation
prob04659
Th17 cell differentiation
prob05145
Toxoplasmosis
prob05160
Hepatitis C
prob05161
Hepatitis B
prob05162
Measles
prob05164
Influenza A
prob05165
Human papillomavirus infection
prob05167
Kaposi sarcoma-associated herpesvirus infection
prob05168
Herpes simplex virus 1 infection
prob05169
Epstein-Barr virus infection
prob05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
127231265 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
127231265 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
127231265 (Tyk2)
04621 NOD-like receptor signaling pathway
127231265 (Tyk2)
04658 Th1 and Th2 cell differentiation
127231265 (Tyk2)
04659 Th17 cell differentiation
127231265 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
127231265 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
127231265 (Tyk2)
05160 Hepatitis C
127231265 (Tyk2)
05171 Coronavirus disease - COVID-19
127231265 (Tyk2)
05164 Influenza A
127231265 (Tyk2)
05162 Measles
127231265 (Tyk2)
05168 Herpes simplex virus 1 infection
127231265 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
127231265 (Tyk2)
05169 Epstein-Barr virus infection
127231265 (Tyk2)
05165 Human papillomavirus infection
127231265 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
127231265 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
prob01001
]
127231265 (Tyk2)
Enzymes [BR:
prob01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
127231265 (Tyk2)
Protein kinases [BR:
prob01001
]
Non-receptor tyrosine kinases
JAK family [OT]
127231265 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
127231265
NCBI-ProteinID:
XP_051052713
UniProt:
A0AAU9ZR97
LinkDB
All DBs
Position
Unknown
AA seq
1186 aa
AA seq
DB search
MVTNMPLCRRRATSEDSKAHGTEAQPPAPTGKLMVLLHWAGPEGGEPWATFSQAALSAED
ICIHIAHKVGITPPCLNLFALYDAQAKVWLPPNHILDTSRDVNLSLYFRMRFYFRNWHGM
NPQEPAVYRYGSPGTETSSERAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEE
IHHFKNESLGMAFLHLCHLALCRGVPLEEMAREISFKKCIPRSFRQHIRQHNALTRLRLR
RVFRRFLRAFQPGHLSQQVVMVKYLATLERLAPRFGSEHIPVCHLEVLDQPERDPCYIQN
SGQTIGDPDSELATRLPTHEVLVTGTGGIQWHPLQNQESERGSIRENPQGNRSLKKAKAS
EAGEQLAKSPGEPPWTYFCDFQDISHVVLEECRVRIHLQDNKCLLLCLRSRAEALSFVAL
VDGYFRLTADSSHYLCHEVAPPRLLTSIQNGIHGPLMDPFVQAKLWPEDGLYLIQWSTSH
LHRLILTVAHRNPAPSSGPKGLRLRKFPITQQPGSFVLDGWGRSFDSVGDLRVALQGCSL
RAGDNCFPLHHCCLPRPGEISNLVIVRGSSAHTRPLNLSQLSFHRVHQDEITQLSHLGQG
TRTNVYEGLLRVGDPEEGKVDSGCPPEPGGCTRQQLRVVLKVLDPSHHDIALAFYETASL
MSQVSHVHLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGRVPMTWKMVVAQQLASA
LSYLEDKNLVHGNVCGRNILLARLGLEEGTSPFIKLSDPGVGQGALSREERVERIPWTAP
ECLSGEASSLGTATDMWGFGATLLEICFDGEAPLQGRRPSEKERFYTKQHQLPQPSCPEL
ATLTRQCLTYEPAQRPSFRTILRDLTRLQPQNLVGISAVNADSTASDPTVFHKRYLKKIR
DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRTGWQREIEILRTLYHEHIVK
YKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHGQRYIH
RDLAARNVFLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYA
SDVWSFGVTLYELLTYCDSSQSPPTKFIELIGVTQGQMTVLRLTELLERGERLPRPDRCP
CEIYLLMKNCWESEASFRPTFQNLVPILKTAQEKYQGQVPSVFSVC
NT seq
3561 nt
NT seq
+upstream
nt +downstream
nt
atggtgacaaacatgcctctgtgtcgtcggagagccacctcggaagacagcaaggcacat
ggcacagaagctcagcccccagcgcccacgggaaagttgatggtgctgctgcactgggct
ggaccagagggtggggaaccctgggccaccttcagccaggcagctctgagtgcagaggat
atctgcatccacatcgcacacaaagtgggcatcactccaccctgcttgaatctcttcgcc
ctctatgatgcacaggccaaggtctggctgcccccaaaccacatcctagacacttcccga
gatgtgaatctgagtctatatttccgaatgaggttttacttccggaactggcatggcatg
aatccccaggagccagctgtataccgatatggttccccagggacagagacttcctcggaa
cgggcagaacagggtgtgcagctcttggactctgcctcttttgaatacctctttgagcag
ggaaagcatgagttcatgaacgatgtggtatctctgcgggacctgtctagtgaggaagag
atccaccactttaagaacgagagcttaggcatggcctttttacacctctgccaccttgct
ctctgccgtggtgttcctctggaggagatggccagagagatcagctttaagaaatgcatc
cctcgttccttccgccagcacattcgccagcacaatgcactgacacgcctgcgtctccgc
agagttttccggcgattcttgagagcctttcagcctggccacctctcccagcaggttgtg
atggttaagtacttggccacactggagcggctggctcctcgatttggctcagagcacata
ccggtgtgtcatttggaggtactggaccagcctgagagagacccgtgctacatccagaac
agtgggcagactattggggacccagactcagagctggccaccaggcttcccacccacgag
gtactggtgacaggcaccggaggtatccagtggcatccacttcagaaccaggaatctgag
agaggtagcatcagagaaaatccccaaggcaaccggtctctgaagaaagcaaaagcctct
gaggctggagagcagctggcaaagagccctggagagccaccctggacttacttctgtgac
ttccaggacatttcccatgtggtgctagaggaatgtcgagttcgcatacaccttcaggac
aacaagtgcttgttgctgtgcctccgttcccgggctgaggccctgtcctttgtggccctg
gtggatggttatttccgcttgactgctgactccagccactacctgtgccatgaggtggca
cccccgaggctgttgactagcatccagaatggcatccatgggcctctgatggatccattt
gtgcaagccaagctgtggccagaggacggcctctacctgattcagtggagcaccagccat
cttcaccgcctgatcctcactgtggcccatcgaaatccagctcccagcagtggccctaag
ggcctgcgtctccgaaagttccccatcacccagcaacctggatcctttgtgctggatggc
tggggtcgctcctttgacagtgtgggggaccttcgggtggccttgcagggctgctcattg
cgggctggagacaactgtttccccttgcaccactgctgcctgccccggccaggagaaatc
tccaacctcgtgatcgtgcgagggtctagtgcccacacccggcctcttaacctcagccag
ctcagcttccacagggttcaccaggatgagatcacacagctgtcccacttgggtcaaggc
acaaggaccaatgtttatgagggccttctaagagtaggagaccctgaggaaggcaaagtg
gacagtggatgtccccctgaacctggtgggtgcactaggcagcagcttcgagtagtgctt
aaagtcttggaccccagtcaccatgacattgccttggccttctatgaaacagctagcctc
atgagtcaggtgtcacacgtgcacctggctttcctgcatggtgtctgcgtgcgtggctca
gagaatatcattgtgacagagttcgtagaacatggtcccttggatgtgtggttacggcga
cagagggggcgagtgcccatgacctggaagatggttgtggctcagcagctggccagtgcc
ctcagctacctggaagataagaatctggttcacgggaacgtatgtggccggaacatcctg
ctggcccggttgggactagaggagggtaccagccccttcatcaagctaagtgatcctggt
gtgggccaaggtgccctctccagggaggagcgggtggagcgcatcccctggacagctcct
gagtgcctgtctggagaggccagtagcttgggtactgccactgacatgtggggctttggt
gccaccctccttgagatttgctttgatggagaggcacccctgcagggtcgccgtccctct
gagaaagaacgattctacacaaagcagcaccagctgcctcagccctcatgcccggagctg
gccacactcacccgccagtgcctgacctatgaaccagcacagcggccatcattccgcacc
attttgcgggacctcactaggctgcagccacagaatcttgtgggtatctcagctgtgaat
gcagactcaacagcatcagaccccactgttttccacaagcgttatttgaaaaagatccgg
gatttgggcgagggtcactttggaaaggtcagcctgtactgctatgatccaaccaatgat
ggcactggcgagatggtggccgtgaaagcccttaaagagggctgtggtccccagctccgc
acaggctggcagcgggagatcgaaattctacggaccctgtaccatgaacacattgtcaag
tacaaaggctgctgtgaggatcaaggagagaagtctgtacagctggtcatggaatacgtt
cccttgggtagcctccgggactacctgccaaggcacagcgttgggctggcacagctcctg
ttgttcgcccagcagatctgcgagggcatggcctacctgcacgggcagcgctatattcac
cgagacctagccgcgcgcaacgtgtttctggacaacgacaggctggtcaagattggagac
tttggcctagccaaggcagtgcctgaaggccacgaatactaccgcgtgcgcgaggacggg
gacagcccggtgttctggtatgccccggaatgcctgaaggagtgcaaattttactatgca
tcagatgtctggtccttcggggtgacgttgtatgagctgttgacgtactgtgactctagt
cagagcccccccacgaaattcatcgagctcatcggagtcacccagggccagatgacggtg
ttgaggctcaccgagttgctggaacgaggagagaggctgcctcggccagacagatgtcct
tgtgagatctatctcctcatgaagaactgctgggagtcagaggcctcctttcggcccacc
ttccagaatcttgtgcccatcctcaagacagcccaggagaagtaccaaggccaagtgcct
tctgtgttcagtgtgtgctaa
DBGET
integrated database retrieval system
