Phodopus roborovskii (desert hamster): 127233323
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Entry
127233323 CDS
T08852
Symbol
Plce1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob00562
Inositol phosphate metabolism
prob01100
Metabolic pathways
prob04014
Ras signaling pathway
prob04015
Rap1 signaling pathway
prob04020
Calcium signaling pathway
prob04024
cAMP signaling pathway
prob04070
Phosphatidylinositol signaling system
prob04919
Thyroid hormone signaling pathway
prob04933
AGE-RAGE signaling pathway in diabetic complications
prob05205
Proteoglycans in cancer
Module
prob_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
127233323 (Plce1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
127233323 (Plce1)
04015 Rap1 signaling pathway
127233323 (Plce1)
04020 Calcium signaling pathway
127233323 (Plce1)
04070 Phosphatidylinositol signaling system
127233323 (Plce1)
04024 cAMP signaling pathway
127233323 (Plce1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
127233323 (Plce1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
127233323 (Plce1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
127233323 (Plce1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
prob04131
]
127233323 (Plce1)
Enzymes [BR:
prob01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
127233323 (Plce1)
Membrane trafficking [BR:
prob04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
127233323 (Plce1)
Endocytosis
Macropinocytosis
Phospholipase C
127233323 (Plce1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
127233323
NCBI-ProteinID:
XP_051055707
LinkDB
All DBs
Position
Unknown
AA seq
2299 aa
AA seq
DB search
MTSEEMAASVLNPVTQRKVASVQSAVAEDKSEKVSEDTGVPKACAVRHSGQIPNTISQWG
KPEAQPSRSDFSQFLPRASGGVMSDENHNEKCWEKNLPDSVKNHAVNCNSLLQSHQCDLP
QSQLCVACDSVTGEDLCLPTGISSPLEREAFPGIQLEMDAPPMDVSPLGKETGMTGASGP
HPDSNKAVFHFRYEADRTMSDAFHTLSEKLILDDCANCVTLPGQQQKKNHMAYTYKLAGL
TRNCGIEDGQWQCDHCSSLHNKYLCFDSSCQQADDLVCSSGRVCREGLTHSLPAKAFLSP
LEDFSDSCEDGDEFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGTAA
WNHVVQRRVRLLGPCGDVMESLSTMDGRPRGSQRLPEAQWCLIYSAVRRGDETEDTVGSL
LHCSRQLPTSETACGRIRDGPCLWQCVRDTECEYRATLQRTSIAQYITGSLLEATTSLGA
RSGLLSTFGGSTGRIMLKERQPGTSMANSNTVPSSSAGISKELIDLQPFIQFPEEVASIL
TEQEQNIYRRVLPMDYLCFLTRDLSSPECQSSLPHLKASISASILTSQNGEHNALEDLVM
RFNEVSSWVTWLVLTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM
WQFMDQSDIETMRSLKDVMAQHESSLEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDG
TSGLLKLCPRYSSQEAALEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSR
SLEMEEEDSSSEGTGSRKNSLKDKTRWQFIIGDLLDSENDIFEKSKECDLHGSEETQKAF
EHGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWMKPPTA
SPAGARPKLGMLSNMSEPGKFPSLGNAGLSGLAEGILDLFSVKAVYMGHPGIDIHTVCVQ
NKLGSLLLPETGVTLLYGLQTTDNRLLHFVAPKHTAKMIFSGLLELTTAVRKIKKFPDQR
QQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGMSAKNAEKPSMQRNNTL
GISTTKKKKKMLMRGESGEATDDETATRKAKMYRECRSRSGSDPQDVNEQEDSEANVITN
PPNPPHSRRAHSLTTAGSPNLATGMSSPISAWSSSSWHGRIKGGMKGFQSFMVSDSNMSF
IEFVELFKSFSVRSRKDLKDIFDIYSVPCNRSASESAPLYTNLTIEENASDLQPDLDLLT
RNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFGVGILQLNDFLVN
CQGEHCTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNFASKNDESQENKKELQ
LPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCWDGDDGMPIIYHGHT
LTTKIPFKEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMADIFKSVFGEKLVAKFLF
ETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMHAQAFTGGNANPP
PASNEEEDDEEDEYDYDYESLSDADVLTASPLPNSQEDNILEDKPENKSCADKLQFEYNE
EIPKRIKKADNSSCNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLIIYCQAVKFPGLS
TLNSSGSSRGKERKSRKSIFGNNPGRMSPGEAASFNRTSGKSSYEGIRQTWEESCSPVSP
STSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNP
LMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKSCPMYQKFSPLER
DLDNMDPAIYSLTIISGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWN
EQFLFRVHFEDLVFLRFAVVENNSSAIMAQRIIPLKALKRGYRHLQLRNLHNEILEISSL
FINSRRMEENPSGSTMPASLMFNTEERKCSQTHRVTVHGVPGPEPFAVFTINGGTKAKQL
LQQILVIDQDTKLSDYFLMEEKYFISKEKNECKKQPFQRAVGPEEDIVQILNSWFPEEGY
VGRIVLKPQQETLEEKSIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQD
VIQQTLCKAKYSYSILNNPNPGDYVLLEEVMKDTPNKKSSTPKSSQRILLDQECVFQAQS
KWKGAGKFILKLKEQVQASREDKRRGISFASELKKLTKSTKQPRGLTSPPQLVTPESVQI
KEEKPMGALSSGDTAAYQQ
NT seq
6900 nt
NT seq
+upstream
nt +downstream
nt
atgacttccgaagaaatggcagcttctgtcctcaaccctgtgactcagaggaaagtggcc
tctgtccagtcagcagtggcagaggacaagagtgaaaaggtctcagaagataccggtgtt
ccaaaggcatgtgctgtcaggcacagcggccagatccctaataccatctcacagtggggc
aaacctgaggcccagccttccagaagtgacttctctcagttcctcccaagagcaagtgga
ggagtaatgagtgatgagaaccacaatgaaaagtgctgggagaaaaacctaccagattct
gtgaaaaaccacgccgttaactgcaacagcctcttgcaaagccaccagtgtgaccttcct
cagagccagctttgtgtagcctgtgactccgtcacaggagaggacctgtgtttgccaact
ggaatttcttctccactggaaagggaggcgttccctggaattcaactggagatggatgct
cctcccatggatgtaagccctttgggaaaggagactggaatgacaggggccagcggacct
caccccgacagcaacaaggcagtatttcatttccgttatgaagctgacagaacaatgtca
gacgctttccacaccctgtcagaaaaactaattttggatgactgtgcaaattgtgtgact
ctccccgggcagcaacagaagaaaaatcacatggcgtatacttataaactagcgggactg
acaagaaactgtggcatcgaggatgggcagtggcagtgtgatcattgcagctcactgcat
aacaaatacctgtgctttgacagttcctgccagcaggctgatgacctggtctgctcaagt
ggtagagtttgcagggagggcctcactcacagtctacctgcaaaggcttttctgagccct
ttggaggatttctctgacagttgtgaagatggagacgagttttttaaaagcaaaaaggag
cggtccaccttgttagtcagaaggttttgtaaaaatgacagggaagttaagaagtctgta
tatactgggactagagcaatcatgaggacactgccttctggccatattgggacagctgct
tggaaccatgttgttcagaggagagtgaggctcttaggaccttgtggagatgtaatggaa
tctctgtcaacaatggatggaaggccacgtgggagccaacgtctacctgaggcccagtgg
tgtctgatctacagtgcagtgagaagaggagacgaaacagaagatacggttggatctctt
ctccattgctccagacagcttccaacctctgagacagcctgtggaaggattagagacggc
ccatgcttatggcaatgtgtacgagacaccgaatgtgagtaccgggccaccctccaaagg
acatccatagctcagtacatcactggttctctcctggaggcaaccacctctttaggagca
agaagcggccttctcagtaccttcggaggatccactggacgaataatgctgaaagaacgc
caaccaggcacctctatggccaattccaatactgttccttcaagttcagctgggatcagc
aaggagctgattgacctccagcccttcattcagttcccggaggaagtggccagcatcctg
acagagcaggagcagaacatttaccgaagggtcctgcccatggactacctttgtttctta
acccgggacttgagttcccctgaatgccagagttccctgccccatctcaaagcgtccatc
tcagcatcaatcctcacttctcagaatggagagcataatgcccttgaagaccttgtgatg
agatttaatgaggtgagctcctgggtaacatggctggtcctcacagcaggctccatggag
gaaaagcgagaagtcttctcatacttggtgcacgtggccaaatgctgctggaacatgggc
aactacaacgctgtcatggagttcctggctggcctcaggtcaaggaaagttctaaagatg
tggcagttcatggatcagtctgacatagagacgatgaggagcctgaaggatgtcatggct
cagcacgagtcctccctggagtacaagaaggtggtgactcgggccctgcacatcccgggc
tgcaaggtggtccccttctgtggcgtcttcctgaaggagctctgtgaggtgcttgatggc
acctctggcctgctgaaactctgtccgcggtacagctcccaggaagcagctctggagttt
gtggctgattacagtggacaagataacttcttgcagcgagtgggacagaacggcttgaag
aactcagagaaggagtccacggtcaacagcatctttcagatcatccggagctgcagtcga
agcttggagatggaggaggaggacagctccagtgaagggaccggctccaggaaaaactcc
ttgaaggataaaacccgatggcagtttataattggagatttgctggattcagaaaatgac
atctttgagaagtccaaagaatgtgaccttcatggatcagaggagacacagaaggccttt
gagcatgggacagagctcatcccatggtacgtgctgtccatccaagctgatgtgcaccag
ttcctattgcagggggccacagtcatccactacgaccaggacacacatctctctgcccgc
tgctttctccagttacagcctgacaatagcaccttgacctggatgaagcctcccaccgcc
tccccagctggtgccagacccaagcttggtatgcttagtaacatgtctgaacctggcaag
ttcccatcactgggcaatgctgggctgagtggcctggccgagggtatcctggatctgttc
tcagtaaaggctgtatacatgggacacccaggcattgatatacacactgtgtgtgttcag
aacaaactgggtagcctgcttctcccagagactggggtaacactgctctacggactccag
accactgacaatagactcttgcactttgtggcgcccaagcacacagctaaaatgattttc
agtggactgctggaactcacgacagctgtgagaaagataaagaagttccctgaccaaaga
caacagtggcttcggaaacagtatgtcagcctctatcaggaagatggtcggtatgaaggc
ccaaccttggctcatgccgtggagttgtttggtggcagacgatggagcgctagaaacccc
agccctgggatgtcagcaaagaacgctgagaagcctagcatgcagagaaacaacaccctg
ggcataagcaccaccaagaaaaagaagaaaatgctcatgaggggagagagtggagaggcg
actgacgacgagacggcgacccgcaaggccaaaatgtacagagagtgtcgcagccggagt
ggttctgatcctcaggacgttaacgaacaagaagactcagaagccaatgtcatcaccaac
cctcccaatcccccccattccagaagagctcactctttgaccacggctgggtcccccaac
ttggctacggggatgtcatctcccatcagtgcctggagcagcagcagctggcatgggcgg
atcaaaggaggaatgaagggcttccagagcttcatggtttcagacagcaacatgagtttc
attgaatttgtcgagctgttcaaatcattcagcgtcaggagccgcaaggacctgaaggac
atctttgacatctactctgtaccctgcaatcggtctgcctctgagtcagcccccctgtac
accaacctgaccattgaagaaaacgccagtgaccttcagcctgacctagatttgctgacc
agaaacgtctcagacttggggctgttcattaagagtaaacaacagctttctgacaaccag
aggcagatatctgatgctattgcagcagcgagcattgtgactaatggcactgggattgag
agcacatccctgggcatattcggggttggcatactccagctcaatgacttcctggtgaat
tgccaaggagagcactgcacgtatgatgaaattctcagcatcatccagaaattcgagcct
agcgtcagtatgtgtcaccagggcctaatgtcgtttgaagggtttgcaaggtttctgatg
gataaagataatttcgcctccaaaaatgatgagtcacaggagaacaagaaagaacttcaa
ctgcccctctcctactattacattgaatcttcacacaatacctacctcacaggccatcag
ctcaagggagaatcctctgtggaactgtacagccaggtcctcttgcaaggatgcaggagc
atagagctggactgctgggacggagatgacggcatgcccattatttatcatggacacaca
ctgacgaccaagatccccttcaaggaagtggtggaagccatcgatcgcagtgccttcatt
acctctgacctgccaatcatcatatccattgagaaccactgttcattgcctcaacaacga
aaaatggcagacattttcaagagtgtgtttggagaaaagctggtggctaaattcttattc
gagacagatttttcggatgatccaatgcttccctcacctgaccaacttaggaggaaagtg
cttcttaaaaacaagaagctaaaggcccatcagacgccagtcgacatcctgaaacaaaag
gctcatcagttagcatccatgcacgcacaggctttcactggtgggaatgccaaccccccg
cctgccagtaatgaggaagaggacgatgaagaggatgaatatgattatgattatgaatcc
ctttccgatgcagatgtccttactgcttcccctcttcctaacagtcaggaagacaatatt
ctggaagacaagcctgaaaacaaatcctgtgcagacaagcttcagtttgagtacaatgaa
gaaatccccaagaggataaagaaagcagataactcttcttgcaataagggaaaggtgtat
gacatggagctgggggaggagttttacctccctcaaaacaaaaaggaaagcagacagatt
gcgccagaactctctgacctcatcatctactgccaggcagtaaaatttccaggcctgtcg
actctaaattcatctggctctagcagagggaaagaaaggaaaagcaggaagtccattttt
ggcaacaatcctggcagaatgagcccaggagaggcagcatccttcaacagaacatctgga
aaaagttcctatgaaggaattcggcaaacctgggaggaatcgtgttctccagtcagcccg
agcacatccctcagcgctatcattagaactcccaaatgctatcatatctcctcactgaat
gaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacaccgct
tgtcagctactgaggacctacccggcggcgacccgaatcgactcatccaatcccaatccc
ctcatgttctggctccacgggatacagcttgtagccctcaactaccagacggatgatctt
cctttacatttaaatgctgcaatgtttgaggcaaatggtggctgtggttatgttttgaag
ccccctgtcctgtgggataaaagctgccccatgtaccaaaagttttctccactggaaaga
gacctagacaacatggaccctgctatctattctttaactatcatctctggccaaaatgtg
tgccccagtaacagcaccggaagcccgtgcattgaggttgatgtcttgggcatgcccctg
gacagctgccatttccgcacaaagcccatccatcgaaacactctgaaccccatgtggaac
gaacagtttctcttccgggttcactttgaagatcttgtattccttcgttttgcagttgtg
gaaaacaacagttcggcaataatggctcagagaatcattccactcaaagctttgaaacga
ggctatcgccatcttcagctgcgtaacctccacaatgaaatattggagatctctagctta
ttcataaacagcagaaggatggaagaaaatccctccggcagtaccatgccagcctctttg
atgtttaatactgaagagaggaagtgttctcagactcacagagtcacagtgcatggtgtt
ccaggtccagagccctttgctgttttcactataaatggaggcaccaaggcaaagcagctt
ctccagcagattctggtgattgaccaagacaccaaacttagtgactactttctgatggaa
gagaagtattttatatctaaggaaaagaatgaatgcaagaaacaaccattccagagagct
gtgggtccagaagaagatatcgtgcagattttaaacagctggtttccagaagaaggctac
gtgggcaggattgtcttaaagccccaacaggaaaccctagaagagaaaagcattgtccaa
gatgacaaagaagtgatcttgagctcagaggaagagagtttctttgtccaagttcatgat
gtctctccagagcaaccccgaactgtcatcaaagccccccgggtcagcactgcacaggat
gtcattcagcagaccttatgcaaagccaaatattcctacagcatcctgaacaaccccaac
ccaggtgactatgtgcttttggaagaggtgatgaaagacacacccaataagaagtcttcc
actcccaaatcctcacagaggatccttttggaccaagagtgtgtgtttcaagcccaaagc
aagtggaaaggtgcagggaaattcatcctcaagctgaaggagcaggttcaggcatccagg
gaagataaaaggaggggcatctcctttgcaagtgaactcaagaaactcactaagtccact
aagcagccccgaggactcacttcacctcctcagcttgtgacccccgaaagtgtccaaatc
aaggaggagaagcctatgggtgccttgtcctctggtgacacagcagcttaccagcagtga
DBGET
integrated database retrieval system
