Phodopus roborovskii (desert hamster): 127234658
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Entry
127234658 CDS
T08852
Symbol
Plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
prob
Phodopus roborovskii (desert hamster)
Pathway
prob00562
Inositol phosphate metabolism
prob01100
Metabolic pathways
prob01521
EGFR tyrosine kinase inhibitor resistance
prob04012
ErbB signaling pathway
prob04014
Ras signaling pathway
prob04020
Calcium signaling pathway
prob04062
Chemokine signaling pathway
prob04064
NF-kappa B signaling pathway
prob04066
HIF-1 signaling pathway
prob04070
Phosphatidylinositol signaling system
prob04072
Phospholipase D signaling pathway
prob04360
Axon guidance
prob04370
VEGF signaling pathway
prob04380
Osteoclast differentiation
prob04611
Platelet activation
prob04613
Neutrophil extracellular trap formation
prob04625
C-type lectin receptor signaling pathway
prob04650
Natural killer cell mediated cytotoxicity
prob04662
B cell receptor signaling pathway
prob04664
Fc epsilon RI signaling pathway
prob04666
Fc gamma R-mediated phagocytosis
prob04670
Leukocyte transendothelial migration
prob04722
Neurotrophin signaling pathway
prob04750
Inflammatory mediator regulation of TRP channels
prob04919
Thyroid hormone signaling pathway
prob04933
AGE-RAGE signaling pathway in diabetic complications
prob04935
Growth hormone synthesis, secretion and action
prob05167
Kaposi sarcoma-associated herpesvirus infection
prob05169
Epstein-Barr virus infection
prob05170
Human immunodeficiency virus 1 infection
prob05171
Coronavirus disease - COVID-19
prob05200
Pathways in cancer
prob05205
Proteoglycans in cancer
prob05206
MicroRNAs in cancer
prob05214
Glioma
prob05223
Non-small cell lung cancer
prob05225
Hepatocellular carcinoma
Module
prob_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
prob00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
127234658 (Plcg2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
127234658 (Plcg2)
04014 Ras signaling pathway
127234658 (Plcg2)
04370 VEGF signaling pathway
127234658 (Plcg2)
04064 NF-kappa B signaling pathway
127234658 (Plcg2)
04066 HIF-1 signaling pathway
127234658 (Plcg2)
04020 Calcium signaling pathway
127234658 (Plcg2)
04070 Phosphatidylinositol signaling system
127234658 (Plcg2)
04072 Phospholipase D signaling pathway
127234658 (Plcg2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
127234658 (Plcg2)
04613 Neutrophil extracellular trap formation
127234658 (Plcg2)
04625 C-type lectin receptor signaling pathway
127234658 (Plcg2)
04650 Natural killer cell mediated cytotoxicity
127234658 (Plcg2)
04662 B cell receptor signaling pathway
127234658 (Plcg2)
04664 Fc epsilon RI signaling pathway
127234658 (Plcg2)
04666 Fc gamma R-mediated phagocytosis
127234658 (Plcg2)
04670 Leukocyte transendothelial migration
127234658 (Plcg2)
04062 Chemokine signaling pathway
127234658 (Plcg2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
127234658 (Plcg2)
04919 Thyroid hormone signaling pathway
127234658 (Plcg2)
09156 Nervous system
04722 Neurotrophin signaling pathway
127234658 (Plcg2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
127234658 (Plcg2)
09158 Development and regeneration
04360 Axon guidance
127234658 (Plcg2)
04380 Osteoclast differentiation
127234658 (Plcg2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
127234658 (Plcg2)
05206 MicroRNAs in cancer
127234658 (Plcg2)
05205 Proteoglycans in cancer
127234658 (Plcg2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
127234658 (Plcg2)
05214 Glioma
127234658 (Plcg2)
05223 Non-small cell lung cancer
127234658 (Plcg2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
127234658 (Plcg2)
05171 Coronavirus disease - COVID-19
127234658 (Plcg2)
05167 Kaposi sarcoma-associated herpesvirus infection
127234658 (Plcg2)
05169 Epstein-Barr virus infection
127234658 (Plcg2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
127234658 (Plcg2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
127234658 (Plcg2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
prob04131
]
127234658 (Plcg2)
Enzymes [BR:
prob01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
127234658 (Plcg2)
Membrane trafficking [BR:
prob04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
127234658 (Plcg2)
Endocytosis
Macropinocytosis
Phospholipase C
127234658 (Plcg2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
SH3_1
C2
SH3_9
PH
EF-hand_PLCG1
PH_12
SH2_1
SH3_2
PH_14
GDPD
Motif
Other DBs
NCBI-GeneID:
127234658
NCBI-ProteinID:
XP_051057690
LinkDB
All DBs
Position
Unknown
AA seq
1267 aa
AA seq
DB search
MNTMVNVDTLPEYEKSQIKRALELGTVMTVFSARKGTSERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKASASRHKGDCCFTIFYGTQFVLSTLSLATDSKED
AVKWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKAILPMVNFKVS
SVKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDA
SAVYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRE
NSIWEEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIEL
DCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCGVEQQRYMA
KVFKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDIDVNVEDKKDEHKTQ
GELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQAVEEELVQDTPPTELHFGEKWFHKKVE
RRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMK
YYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAED
MLMRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVS
YYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALY
DYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQ
IIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDHVEELFE
WFQSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSF
VETKADSIVRQKPIALLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTAD
KYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKILMTLTVKVLGARHLPKLGR
SIACPFIEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYE
EDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLECEEELYS
SCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRV
SNSRFYS
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
atgaacaccatggtcaatgtggacacccttccagaatatgagaagagtcagatcaagaga
gccctggagctagggacggtgatgactgtgttcagtgcccgcaagggcacctcagagcgg
aggacggtgcaggtgatcatggagactcggcaggtggcgtggagcaagactgcggacaag
atcgagggcttcttggacatcatggaaataaaagaaatccgtccagggaagaactccaag
gactttgagcgagccaaggcctcagcctcccgccacaagggagactgctgcttcaccatc
ttctacggcacccagttcgtcctcagcaccctcagtctggcaactgactcaaaggaggat
gcagtgaagtggctctctggtttgaagatcttacaccaggaagcgatgagtgcatctact
cccaccatgattgagagttggctgagaaagcagatttattcagtagatcaaaccagaaga
aacagcatcagcctccgagagctgaaggccatcttgcccatggtcaacttcaaagtgagc
agtgtcaagtttctcaaggacaagctggtggaaattggtgcacagaaagatgagctcagt
tttgaacagttccatctcttctataaaaaactcatgtttgaccagcaaaaatcgatactt
gatgaattcaagaaggactcctctgtgttcattctagggaacacagacaggcctgacgcc
tctgctgtctacctacaggacttccagaggtttcttctacacgaacaacaggagctatgg
gctcaggatctgaacaaagtccgggaacggatgaccaagtttattgacgacaccatgagg
gaaaccgcagagcccttcttgtttgtggatgagttcctcacgtacctgttttcacgggag
aacagcatctgggaggagaagtatgatgtagtggacatgcaggacatgaacaatcccttg
tcgcattactggatctcctcttcccacaacacgtacctcacgggggaccagctgcgtagt
gagtcctccacagaagcatatatccgctgtctgcgtgctggctgtcgttgcatagagttg
gactgctgggatgggcctgatggcaaacccatcatctaccatggctggactcggaccacc
aagatcaagtttgatgacgttgttcaggccatccgagaccacgcctttgtcacctccagc
ttccccgtaatcttgtccatcgaggagcactgcggcgtggagcagcagcgttacatggcc
aaggtgttcaaggaagtgttaggagacctgttgttgacaaagcccacggaggccagtgct
gaccagttgccctcacccagccagcttcgagagaagatcattatcaagcataagaagctg
ggcccccgaggtgacatcgatgtcaacgtagaggacaagaaagatgagcacaagacccag
ggagagctatacatgtgggactccatcgaccagaaatggactcgacactactgtgccatt
gctgatgccaagctgtccttcagtgatgacatcgaacaggctgtggaggaggagctggtc
caggacactcctcccacggagctgcattttggggagaaatggttccataagaaagtggag
aggaggaccagtgcagagaagctactgcaagaatactgtgctgagacaggggccaaggat
ggcaccttcctggtgcgtgagagcgagaccttccccaacgactacacactctccttctgg
cggtctggtcgggtgcagcactgtcgaatccggtccaccatggagggtggggtcatgaag
tactacctgacagacaacctcacgttcaatagcatctacgccctcatccagcactaccgt
gaggcacacctacgctgtgcagagttcgagctgcggctcacggacccagtgcccaacccc
aacccacacgagtccaagccgtggtactatgacaggctgagcaggggtgaagcggaggac
atgttgatgcggattccccgagatggagccttcctcatccggaagcgagaagggacggac
tcctatgccatcaccttcagggccaggggcaaggtgaaacactgtcgcatcaaccgggat
ggtcggcactttgtgctggggacctctgcctactttgagagcctggtggagcttgtcagc
tactatgagaagcatgcactctatcgcaagatgaggctgcgctatcctgtgacccctgag
cttctggagcgatataatatggaaagagacatcaactctctctatgatgtcagcaggatg
tatgtggacccaagcgaaatcaacccttccatgcctcagaggactgtgaaagcactctat
gattacaaagccaagcgcagcgatgagttgaccttctgtcgtggtgcccttatccacaac
gtctccaaggagccagggggatggtggaaaggggactatgggacccggatccagcagtac
ttcccatccaactacgtagaggatatctcagcaggtgatgctgaggagatggagaagcag
attattgaagacaatccccttgggtctctctgcagaggcatattggaccttaatacctac
aatgttgtgaaggccccgcaggggaaaaaccagaaagcgttcgtcttcatcctggagcct
aagaagcagggggaccctcctgtggagtttgccaccgaccatgtggaggagctgtttgag
tggtttcagagcatccgggagatcacttggaagattgacaccaaggagaacaacatgaag
tactgggagagaaaccagtccatcgccatcgagctctctgacttggttgtctactgtaag
ccaaccagcaaaaccaaggaccatttggaaaaccctgacttccgagaaattcgctccttt
gtggagacaaaggcggacagcattgtgcggcagaagcccatcgctctgttgcggtacaat
cagaaaggcctcacacgtgtttaccctaagggacagagagttgactcttcaaactacgac
cccttccgcctgtggctgtgtggctcccagatggtggcactcaattttcagactgcagac
aaatacatgcagatgaaccacgcgttgttttcactcaatgggcggacaggctatgtccta
cagcctgagagcatgcggtctgagaagtatgacccgatgccaccggagtcccagaggaag
atcttgatgacactcactgtcaaggttcttggtgcacgacacctccccaaactagggcgg
agtattgcctgtccctttatagaggtggaaatctgtggggctgagtatgacagcaacaag
ttcaagacaacggttgtgaatgacaacggcctcagccctgtctgggctccaacgcaggag
aaggtgacatttgaaatttatgatccaaaccttgcattcctccgctttgtggtttacgag
gaggacatgttcagtgaccccaacttcctggctcatgccacataccccattaaagggatc
aagtcagggtttaggtccgtccctctgaagaatggatacagtgaagacatcgagttggcg
tccctcctggttttctgtgagatgcggcctgtcctggagtgtgaagaggaactctactcc
tcctgtcgccaactgaggaggcggcaagaagagctcaataatcagctcttcctatatgac
acacaccagaacctgcgcggggccaaccgagatgccctagtgaaggagttcaatgtcaac
gagaaccagctgcagctgtaccaggagaagtgcaaccggaggttgagagagaagagagtc
agcaacagcaggttctactcctag
DBGET
integrated database retrieval system
