KEGG   Phodopus roborovskii (desert hamster): 127239025
Entry
127239025         CDS       T08852                                 
Symbol
Akt2
Name
(RefSeq) RAC-beta serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
prob  Phodopus roborovskii (desert hamster)
Pathway
prob01521  EGFR tyrosine kinase inhibitor resistance
prob01522  Endocrine resistance
prob01524  Platinum drug resistance
prob04010  MAPK signaling pathway
prob04012  ErbB signaling pathway
prob04014  Ras signaling pathway
prob04015  Rap1 signaling pathway
prob04022  cGMP-PKG signaling pathway
prob04024  cAMP signaling pathway
prob04062  Chemokine signaling pathway
prob04066  HIF-1 signaling pathway
prob04068  FoxO signaling pathway
prob04071  Sphingolipid signaling pathway
prob04072  Phospholipase D signaling pathway
prob04140  Autophagy - animal
prob04150  mTOR signaling pathway
prob04151  PI3K-Akt signaling pathway
prob04152  AMPK signaling pathway
prob04210  Apoptosis
prob04211  Longevity regulating pathway
prob04213  Longevity regulating pathway - multiple species
prob04218  Cellular senescence
prob04261  Adrenergic signaling in cardiomyocytes
prob04370  VEGF signaling pathway
prob04371  Apelin signaling pathway
prob04380  Osteoclast differentiation
prob04510  Focal adhesion
prob04517  IgSF CAM signaling
prob04518  Integrin signaling
prob04550  Signaling pathways regulating pluripotency of stem cells
prob04611  Platelet activation
prob04613  Neutrophil extracellular trap formation
prob04620  Toll-like receptor signaling pathway
prob04625  C-type lectin receptor signaling pathway
prob04630  JAK-STAT signaling pathway
prob04660  T cell receptor signaling pathway
prob04662  B cell receptor signaling pathway
prob04664  Fc epsilon RI signaling pathway
prob04666  Fc gamma R-mediated phagosome formation
prob04668  TNF signaling pathway
prob04722  Neurotrophin signaling pathway
prob04725  Cholinergic synapse
prob04728  Dopaminergic synapse
prob04810  Regulation of actin cytoskeleton
prob04910  Insulin signaling pathway
prob04914  Progesterone-mediated oocyte maturation
prob04915  Estrogen signaling pathway
prob04917  Prolactin signaling pathway
prob04919  Thyroid hormone signaling pathway
prob04920  Adipocytokine signaling pathway
prob04922  Glucagon signaling pathway
prob04923  Regulation of lipolysis in adipocytes
prob04926  Relaxin signaling pathway
prob04929  GnRH secretion
prob04931  Insulin resistance
prob04932  Non-alcoholic fatty liver disease
prob04933  AGE-RAGE signaling pathway in diabetic complications
prob04935  Growth hormone synthesis, secretion and action
prob04936  Alcoholic liver disease
prob04973  Carbohydrate digestion and absorption
prob05010  Alzheimer disease
prob05017  Spinocerebellar ataxia
prob05132  Salmonella infection
prob05135  Yersinia infection
prob05142  Chagas disease
prob05145  Toxoplasmosis
prob05152  Tuberculosis
prob05160  Hepatitis C
prob05161  Hepatitis B
prob05162  Measles
prob05163  Human cytomegalovirus infection
prob05164  Influenza A
prob05165  Human papillomavirus infection
prob05166  Human T-cell leukemia virus 1 infection
prob05167  Kaposi sarcoma-associated herpesvirus infection
prob05168  Herpes simplex virus 1 infection
prob05169  Epstein-Barr virus infection
prob05170  Human immunodeficiency virus 1 infection
prob05200  Pathways in cancer
prob05205  Proteoglycans in cancer
prob05207  Chemical carcinogenesis - receptor activation
prob05208  Chemical carcinogenesis - reactive oxygen species
prob05210  Colorectal cancer
prob05211  Renal cell carcinoma
prob05212  Pancreatic cancer
prob05213  Endometrial cancer
prob05214  Glioma
prob05215  Prostate cancer
prob05218  Melanoma
prob05220  Chronic myeloid leukemia
prob05221  Acute myeloid leukemia
prob05222  Small cell lung cancer
prob05223  Non-small cell lung cancer
prob05224  Breast cancer
prob05225  Hepatocellular carcinoma
prob05226  Gastric cancer
prob05230  Central carbon metabolism in cancer
prob05231  Choline metabolism in cancer
prob05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
prob05415  Diabetic cardiomyopathy
prob05417  Lipid and atherosclerosis
prob05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:prob00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    127239025 (Akt2)
   04012 ErbB signaling pathway
    127239025 (Akt2)
   04014 Ras signaling pathway
    127239025 (Akt2)
   04015 Rap1 signaling pathway
    127239025 (Akt2)
   04370 VEGF signaling pathway
    127239025 (Akt2)
   04371 Apelin signaling pathway
    127239025 (Akt2)
   04630 JAK-STAT signaling pathway
    127239025 (Akt2)
   04668 TNF signaling pathway
    127239025 (Akt2)
   04066 HIF-1 signaling pathway
    127239025 (Akt2)
   04068 FoxO signaling pathway
    127239025 (Akt2)
   04072 Phospholipase D signaling pathway
    127239025 (Akt2)
   04071 Sphingolipid signaling pathway
    127239025 (Akt2)
   04024 cAMP signaling pathway
    127239025 (Akt2)
   04022 cGMP-PKG signaling pathway
    127239025 (Akt2)
   04151 PI3K-Akt signaling pathway
    127239025 (Akt2)
   04152 AMPK signaling pathway
    127239025 (Akt2)
   04150 mTOR signaling pathway
    127239025 (Akt2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    127239025 (Akt2)
   04518 Integrin signaling
    127239025 (Akt2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    127239025 (Akt2)
  09143 Cell growth and death
   04210 Apoptosis
    127239025 (Akt2)
   04218 Cellular senescence
    127239025 (Akt2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    127239025 (Akt2)
   04550 Signaling pathways regulating pluripotency of stem cells
    127239025 (Akt2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    127239025 (Akt2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    127239025 (Akt2)
   04613 Neutrophil extracellular trap formation
    127239025 (Akt2)
   04620 Toll-like receptor signaling pathway
    127239025 (Akt2)
   04625 C-type lectin receptor signaling pathway
    127239025 (Akt2)
   04660 T cell receptor signaling pathway
    127239025 (Akt2)
   04662 B cell receptor signaling pathway
    127239025 (Akt2)
   04664 Fc epsilon RI signaling pathway
    127239025 (Akt2)
   04666 Fc gamma R-mediated phagosome formation
    127239025 (Akt2)
   04062 Chemokine signaling pathway
    127239025 (Akt2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    127239025 (Akt2)
   04922 Glucagon signaling pathway
    127239025 (Akt2)
   04923 Regulation of lipolysis in adipocytes
    127239025 (Akt2)
   04920 Adipocytokine signaling pathway
    127239025 (Akt2)
   04929 GnRH secretion
    127239025 (Akt2)
   04915 Estrogen signaling pathway
    127239025 (Akt2)
   04914 Progesterone-mediated oocyte maturation
    127239025 (Akt2)
   04917 Prolactin signaling pathway
    127239025 (Akt2)
   04926 Relaxin signaling pathway
    127239025 (Akt2)
   04935 Growth hormone synthesis, secretion and action
    127239025 (Akt2)
   04919 Thyroid hormone signaling pathway
    127239025 (Akt2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    127239025 (Akt2)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    127239025 (Akt2)
  09156 Nervous system
   04725 Cholinergic synapse
    127239025 (Akt2)
   04728 Dopaminergic synapse
    127239025 (Akt2)
   04722 Neurotrophin signaling pathway
    127239025 (Akt2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    127239025 (Akt2)
  09149 Aging
   04211 Longevity regulating pathway
    127239025 (Akt2)
   04213 Longevity regulating pathway - multiple species
    127239025 (Akt2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127239025 (Akt2)
   05205 Proteoglycans in cancer
    127239025 (Akt2)
   05207 Chemical carcinogenesis - receptor activation
    127239025 (Akt2)
   05208 Chemical carcinogenesis - reactive oxygen species
    127239025 (Akt2)
   05230 Central carbon metabolism in cancer
    127239025 (Akt2)
   05231 Choline metabolism in cancer
    127239025 (Akt2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    127239025 (Akt2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    127239025 (Akt2)
   05212 Pancreatic cancer
    127239025 (Akt2)
   05225 Hepatocellular carcinoma
    127239025 (Akt2)
   05226 Gastric cancer
    127239025 (Akt2)
   05214 Glioma
    127239025 (Akt2)
   05221 Acute myeloid leukemia
    127239025 (Akt2)
   05220 Chronic myeloid leukemia
    127239025 (Akt2)
   05218 Melanoma
    127239025 (Akt2)
   05211 Renal cell carcinoma
    127239025 (Akt2)
   05215 Prostate cancer
    127239025 (Akt2)
   05213 Endometrial cancer
    127239025 (Akt2)
   05224 Breast cancer
    127239025 (Akt2)
   05222 Small cell lung cancer
    127239025 (Akt2)
   05223 Non-small cell lung cancer
    127239025 (Akt2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    127239025 (Akt2)
   05170 Human immunodeficiency virus 1 infection
    127239025 (Akt2)
   05161 Hepatitis B
    127239025 (Akt2)
   05160 Hepatitis C
    127239025 (Akt2)
   05164 Influenza A
    127239025 (Akt2)
   05162 Measles
    127239025 (Akt2)
   05168 Herpes simplex virus 1 infection
    127239025 (Akt2)
   05163 Human cytomegalovirus infection
    127239025 (Akt2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    127239025 (Akt2)
   05169 Epstein-Barr virus infection
    127239025 (Akt2)
   05165 Human papillomavirus infection
    127239025 (Akt2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    127239025 (Akt2)
   05135 Yersinia infection
    127239025 (Akt2)
   05152 Tuberculosis
    127239025 (Akt2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    127239025 (Akt2)
   05142 Chagas disease
    127239025 (Akt2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    127239025 (Akt2)
   05017 Spinocerebellar ataxia
    127239025 (Akt2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127239025 (Akt2)
   05418 Fluid shear stress and atherosclerosis
    127239025 (Akt2)
   05415 Diabetic cardiomyopathy
    127239025 (Akt2)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    127239025 (Akt2)
   04932 Non-alcoholic fatty liver disease
    127239025 (Akt2)
   04931 Insulin resistance
    127239025 (Akt2)
   04933 AGE-RAGE signaling pathway in diabetic complications
    127239025 (Akt2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    127239025 (Akt2)
   01524 Platinum drug resistance
    127239025 (Akt2)
   01522 Endocrine resistance
    127239025 (Akt2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:prob01001]
    127239025 (Akt2)
Enzymes [BR:prob01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     127239025 (Akt2)
Protein kinases [BR:prob01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   127239025 (Akt2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Kinase-like Pkinase_C PH_20 Seadorna_VP7
Other DBs
NCBI-GeneID: 127239025
NCBI-ProteinID: XP_051063783
UniProt: A0AAV0A8A8
LinkDB
Position
Unknown
AA seq 481 aa
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRTIQMVANSLKHRDPGDRAI
ESTCGSPSDSAPSEMMEVAVSKARTKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQR
KLLPPFKPQVTSEVDTRYFDDEFTAQSITVTPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq 1446 nt   +upstreamnt  +downstreamnt
atgaatgaggtatctgtcatcaaagaaggctggctccacaaacgtggtgaatacatcaag
acttggaggccccggtacttccttctgaagagtgatggctctttcatcgggtataaggag
agacctgaggctcctgaccagaccttaccccccctgaacaatttctctgtagcagaatgc
cagctgatgaagactgagaggccacggcctaacacctttgtcatacgctgcctgcagtgg
accacagtcatcgagaggaccttccatgtagactctccagatgagagggaagagtggatg
cggactatccagatggtcgccaacagcctgaagcaccgggacccaggtgaccgtgccata
gagtccacatgtggctcacccagtgactctgccccatccgagatgatggaagtggctgtc
agcaaggcgcgcaccaaagtgaccatgaatgacttcgattatctcaaactccttggaaag
ggcaccttcggcaaagtcatcctagtgcgggagaaggccactggccgctattatgccatg
aagattctgaggaaggaggtcatcattgccaaggacgaagtcgcccacacagtcactgag
agccgcgtgctacagaacaccaggcaccccttccttactgccctgaagtacgccttccag
acccacgaccgcctgtgcttcgtgatggaatatgccaacgggggcgagctcttcttccac
ctctctcgagagcgagtcttcacggaggatcgggcccgattttatggtgcagagatcgtg
tcagctctggagtatttgcactcccgggatgtggtgtaccgtgacatcaagctggaaaac
ctcatgctggacaaagatggccacatcaagatcactgactttggcttgtgcaaagagggc
atcagtgatggggccaccatgaaaaccttctgcggtaccccggagtacttggcgcctgag
gtgctggaggacaatgactacgggcgtgcagtggactggtgggggctgggcgtggtcatg
tacgagatgatgtgtggccgcctgcccttctacaaccaggatcacgagcgcctcttcgag
cttatcctcatggaggagatccgcttcccacgaacgcttgggccagaggccaagtccctg
ctggctgggctgctgaagaaggaccctaagcagaggctcggcggaggtcccagtgacgcg
aaggaggtcatggagcacaggtttttcctcagcatcaactggcaggatgtggtacagaga
aagctcctaccacccttcaagcctcaggtcacttccgaagtggacactaggtacttcgat
gatgagttcacagcgcagtctatcacagtcacacccccggaccgctatgacagcctgggc
tcgctggaactggaccagcggacgcacttcccacaattctcctactcggccagcatccga
gagtga

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