Proteus sp. NMG38-2: LG402_03140
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Entry
LG402_03140 CDS
T11216
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pron Proteus sp. NMG38-2
Pathway
pron00260
Glycine, serine and threonine metabolism
pron00261
Monobactam biosynthesis
pron00270
Cysteine and methionine metabolism
pron00300
Lysine biosynthesis
pron01100
Metabolic pathways
pron01110
Biosynthesis of secondary metabolites
pron01120
Microbial metabolism in diverse environments
pron01230
Biosynthesis of amino acids
Module
pron_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pron_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
pron_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
pron_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
pron00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
LG402_03140 (thrA)
00270 Cysteine and methionine metabolism
LG402_03140 (thrA)
00300 Lysine biosynthesis
LG402_03140 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
LG402_03140 (thrA)
Enzymes [BR:
pron01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
LG402_03140 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
LG402_03140 (thrA)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
PEG10-RTL1_C-capsid
Motif
Other DBs
NCBI-ProteinID:
UDN36670
LinkDB
All DBs
Position
643900..646359
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERVLNVADIAEKKREQGQVALVLSAPAKITNYLVAMIEKTAEGEDP
LTQVREAEQIFANLLQGLREKQPGFDYERLKDKVEREFAEIRHILHGISLLGQCPDSINA
AMICRGEKLSIAIMESVLQARGYNVTVIDPVKNLLAQGHYLESTVDIPESTRRILELNIA
KDDMILMAGFTAGNEKDELVVLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYTCDPRLV
PDARLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPDAPGTLIGDGQK
DESTPVKGITNLNNMAMINVSGPGMKGMVGMAARVFSVMSRAGISVVLITQSSSEYSISF
CVPQKELIRAQKALSDEFYLELKDGVLDPLDIMENVAIISVVGDGMRTLKGISARFFSAL
TRGNINIVAIAQGSSERSISAVIANDSATNAVRLCHQMLFNTNQIVEVFVIGAGGVGNAL
IEQIHRQQAWLKNKHIDLRVCGIANSRAMLTNMQGIDLDNWQQALKEAKTPFSFSQLIRL
EKEYHFLNPVIVDCTSNEEIAQQYANFLQNGFNVVTPNKKANTLSMDYYYQIRQAAEASR
RKFLYDTNVGAGLPVIENLQNLLNAGDELVQFNGILSGSLSYIFGQLDEGKSLSEATFSA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYKLELSDIDVEPVLPTSFDSTGDVASFLS
RLPQVDVEFDAKVEEAQKAGKVLRYVGVINEGQCQVKMMAVDANDPLFKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADVLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttaaaatttgggggaacttcagttgccaatgcagagcgtgtgctgaatgtt
gctgatatcgctgagaaaaaaagagagcaaggacaagtcgctcttgtattatcagcacca
gccaaaataacgaattatttggttgcaatgattgaaaaaacggcagaaggcgaagatcct
ctcactcaagtacgtgaagccgaacaaatttttgccaatttattacaaggtttaagagaa
aaacagcctggtttcgattatgagcgtttaaaagataaagttgagcgtgaatttgctgaa
attaggcacatccttcatggtatttctttattaggtcaatgccctgatagcattaatgca
gcaatgatttgtcgtggtgaaaagctctctatcgccattatggagtctgttttacaagct
cgtggctataatgtcacagttattgatcctgtaaaaaatttacttgcacaaggtcactat
ctagaatctaccgttgatattcctgaatctactcgccgtatcttggaacttaatatcgcg
aaagacgatatgattttaatggctggttttactgcaggtaatgaaaaagatgaactggtt
gtattaggtcgcaatggttcagactactcagccgcagtattagcagcctgtctgcgtgct
gaatgctgtgaaatttggactgatgttgacggtgtttatacttgtgatcctcgtttagta
cctgatgctcgtttattgaagggcatgtcatatcaagaggcaatggaactgtcttacttc
ggtgctaaagttcttcatcctcgcactattgctccaatcgctcagttccaaattccttgt
ttgattaaaaatacaggtaatcctgatgcaccgggtacactgattggcgatggtcaaaaa
gatgagagtactccagttaaagggatcactaaccttaataacatggcaatgatcaacgta
tcaggcccaggtatgaaaggtatggtcgggatggcggctcgcgtattctctgtgatgtcg
agagctggtatttctgttgttcttattacacagtcttcttctgaatacagcatcagtttt
tgcgtaccacaaaaagaactgattagagcgcaaaaagcattatcagatgaattctattta
gaattaaaagatggtgtacttgatccattagatatcatggaaaacgtagcgataatctct
gtcgtgggtgatggtatgcgtacactgaaagggatttcagcgcgattcttctctgcgtta
acacgaggcaatattaatattgttgccattgctcaaggttcgtctgaacgctctatttct
gcagttattgccaacgactcagcaactaatgcggtgcgtttatgtcaccaaatgctattc
aacacaaatcaaatcgttgaagtttttgtgattggtgcgggtggtgtcggtaatgcatta
attgaacaaattcatcgtcaacaggcatggttgaaaaataagcatatcgatcttcgtgta
tgtggcattgctaattcacgcgccatgttaacgaatatgcaaggtattgatttagataat
tggcaacaagctttaaaagaagctaaaacgccgtttagttttagtcagcttattcgctta
gaaaaagagtaccacttcttaaatcctgtgattgttgattgcacatcaaacgaggaaatt
gcgcaacaatacgcaaatttcttacaaaatggttttaatgtggttacaccaaacaaaaaa
gcgaatacgctgtcgatggattattactatcaaatccgacaagccgctgaagcttcacgt
cgtaaatttttatatgacactaatgtgggtgcaggtttaccagttattgaaaacctacag
aacttacttaatgcaggtgatgagttggttcaatttaatggtattctttcaggctcactc
tcttacatttttggccagttagacgaaggtaagagtttgtcagaagcaacgttttcagcg
aaagaaaaaggtttcacagaacctgatcctcgtgatgatctttcgggtatggatgttgcg
cgtaaactgctgattttagcccgtgaagcaggttataaattagagctaagtgatatcgat
gtagagcctgtgttaccgacttcatttgacagcacaggtgatgttgcaagtttcttaagt
cgtttacctcaagttgatgttgaatttgacgctaaggtcgaagaagcacaaaaagccggt
aaagtattacgctatgtcggtgttattaatgaaggtcaatgccaagttaaaatgatggct
gttgatgctaatgatcctctgtttaaagtaaaaaatggtgaaaatgctttagccttttac
actcgctactatcagccaattccattagtgttgcgtggatatggtgcgggtaatgatgtt
actgctgctggagtgtttgcagatgtattacgtaccttatcatggaaattgggggtttaa
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