Paenibacillus roseipurpureus: MJB10_06910
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Entry
MJB10_06910 CDS
T10989
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
proo Paenibacillus roseipurpureus
Pathway
proo00860
Porphyrin metabolism
proo01100
Metabolic pathways
proo01110
Biosynthesis of secondary metabolites
proo01120
Microbial metabolism in diverse environments
proo01240
Biosynthesis of cofactors
Module
proo_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
proo_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
proo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MJB10_06910 (cobA)
Enzymes [BR:
proo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MJB10_06910 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MJB10_06910 (cobA)
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Paralog
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
WNR45825
UniProt:
A0AA96LPY5
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Position
1525529..1527079
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AA seq
516 aa
AA seq
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MAVNKGRVFLVGAGPGDPKLISVRGMEAIQRADVIVYDRLANPRLLKHRKPEAELIFVGK
LPDKHILKQEEINQLLVDLALQGKVVTRLKGGDPSVFGRVGEEAELLADHGITYDIIPGI
TSSIAVPTYAGIPVTHRDFTSSVAIVTGHEYPNKTYSSLNWEHLAKAIGTMVFLMGVANL
EQICRELIRCGKPPEMPVALVRWGTWADQATITGTLADITEKVKAADFKSPAVIIVGEVV
KLRDKLSWIEKKPLFGKRVLVTRARSQASELVDLIDDLGGEPVEFPVIRLQPPSRPEAQE
ALDRALDNLQEYDWIILTSVNGVDFFFRRLRERKIDVRRMGKAHIAAVGPKTAEALAERG
IIANVLPAKFQGEGILDAIQGDLNAGQKVLLPTADLARDYLPARLKELGLEVTEVDVYEN
VLSMDDGEEIIHLLQNQSIHILTFTSSSTVTNLLEALKQLGIEDPQSLLQGVEIACIGPK
TAETVAQAGLPITYMAEEATVASLVQSMIQGGGNPT
NT seq
1551 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgaacaaaggaagagtttttcttgttggggcaggtcctggagatccgaagctg
atctcagtccgcgggatggaagccatccagcgtgcggatgtcatcgtctatgatcgactg
gcgaatccgcggcttttgaagcaccgcaaaccggaagcggaactcatctttgttggcaag
ctgccggacaaacatatattaaagcaagaagaaatcaaccaattgcttgtggatttggct
ttgcaagggaaagtggtcacccggctgaaaggcggagatcccagcgtatttggacgtgtt
ggtgaagaagctgagcttctggcagatcatggcatcacgtacgatatcattcctgggatt
acgtcttccatcgcggttccaacctatgcagggattccagtgacacatcgcgattttacg
tcatctgtggctatcgttacagggcatgaatacccgaacaaaacgtattccagcttaaat
tgggagcatctggcgaaagccattggtacgatggttttcttaatgggcgttgccaattta
gagcaaatctgccgagagttgattcgctgcggcaagccgccagagatgcctgttgcgctc
gtacgctggggaacttgggctgatcaagcgacgataacgggcacgcttgccgatatcaca
gagaaggtaaaagcagcagactttaagtcgccagctgttatcattgtcggcgaagtcgtg
aaactgcgagacaagctgtcatggattgagaagaagcctctattcggcaagcgcgtactg
gtcactagagcacggagccaagcgagtgagcttgttgatttaatcgatgatctcggcggt
gagcctgtagagttccctgtaattcgattgcaaccgcctagtcgtccagaagcccaagag
gcgctagatcgtgcactggacaacctgcaggaatatgactggattatcctgaccagtgtg
aacggggtggacttcttcttccgcaggcttcgcgagcgtaagattgacgttcgccgcatg
ggcaaggcgcacattgcagcagtcggccctaagacagctgaagcgttagcagagcgtggc
attatcgctaacgtcctgccagccaagtttcaaggggaaggcatcctagatgccatccaa
ggggatttgaacgcaggtcagaaggtgctgctgccaacggcagatcttgctcgtgattat
ttgcctgccagactgaaggaacttggcttagaggtaaccgaggtcgatgtgtacgagaac
gtgctgtccatggacgacggggaagaaatcattcatcttttacaaaatcaaagcattcat
attcttacttttacaagctcatcaaccgttacgaatttgctcgaagcattgaaacagcta
ggaattgaagatccgcaatccttgctgcaaggcgtggagattgcctgtattggtcccaaa
acggcagaaaccgtggcgcaagctggcctgccgatcacatatatggccgaagaagcaacc
gttgcttctctggtacaaagcatgattcaaggaggcggaaatccaacatga
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