Proteiniclasticum sp. QWL-01: P6M73_07070
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Entry
P6M73_07070 CDS
T08970
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
proq
Proteiniclasticum sp. QWL-01
Pathway
proq00300
Lysine biosynthesis
proq00550
Peptidoglycan biosynthesis
proq01100
Metabolic pathways
proq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
proq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
P6M73_07070 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
P6M73_07070 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
P6M73_07070 (murF)
Enzymes [BR:
proq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
P6M73_07070 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
WFF74201
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Position
1463321..1464673
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AA seq
450 aa
AA seq
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MEKLTLIEIAQATGGKILFGNDDVTCESVVMDSRKVTENALFIGIKGEQVDGNDYFLTAF
EQGATIALIEKDVDVIPTGQKGLVWVPSTRDALAALAKYYKNRSLTNTRFIAITGSVGKT
TAKDMLCGMLSAKYKVFKTRGNYNNELGLPLMIFSMDSSYDFAVLEMGMSSLGEIHFLAD
IVRPDLALITNIGTSHIEILKTRENILKAKLEITDFFGPDQVLFLNADDPYLAGIKHQTY
QIVTAGIATGIYRAKNISLEPGTIEFDALRGEETLGHIKLEVPGMHNVANGILCFACAHQ
LGISAADLTRMTIDRTVMRLEETQFEHLTVINDAYNASPESAKAGLDTLALRGGRKVALM
GDMKELGDYSAKAHVEVGAYARSRVDVLIAVGDFAKEYGEGFGSQDFHGYPTYEDAVIAL
PNLLDEGDLVYLKASRSMKFERFLSVLERI
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
gtggaaaaacttacactgatagaaatagcccaggccacaggtggcaagatcctgttcggc
aatgacgatgtaacttgcgaatccgtcgtaatggattcccgcaaagtgacggaaaacgcc
ctgttcataggtattaaaggcgaacaggtcgatggcaatgactactttttaaccgccttc
gagcagggggcgacgattgcgctgattgaaaaagacgtggacgtgatcccgaccggacag
aaaggtctggtttgggtgccttccacccgggatgccctggccgccctggctaaatattac
aagaaccgctcgctgaccaatacccgtttcatcgccatcaccggctcggtgggcaaaacg
acggccaaggacatgctctgcggcatgctgtccgccaaatacaaggtctttaagacccgc
ggcaactacaacaatgaactgggactgccgctgatgattttttcaatggattccagctat
gatttcgccgtgctggaaatgggcatgtcttccctgggagaaatccatttcctggcagac
attgtccggccggatctggcgttaatcaccaacatcggcacctcccacatcgaaattttg
aagacccgggaaaatatcctgaaagccaagttggaaattacggactttttcgggccggac
caggttctgttcctcaatgccgatgatccctacctggccggtatcaagcaccagacctac
cagatcgtgacggccggaatcgccaccggcatctatcgagccaaaaacatctcgctggag
cccggcaccattgagtttgacgctctgaggggtgaggaaaccctgggtcacatcaagctg
gaagtacccggcatgcataatgtggccaacggcatcctgtgcttcgcctgtgcccatcag
ctgggcatttccgccgcggatctgacccgtatgaccatcgaccgcacggtcatgcggctg
gaagagactcagtttgagcatctgacggttattaacgacgcgtacaatgccagcccggaa
tccgccaaagccggactggatacccttgctctgcgcggcggacgcaaggttgccctgatg
ggtgacatgaaggaactgggcgactacagcgccaaggctcatgtcgaagtaggggcctat
gcccgctcccgggttgatgtcctcatcgccgtgggcgacttcgccaaggaatacggcgag
ggctttggcagccaggatttccatggctatccgacctatgaggatgccgtcattgctttg
cccaatcttctggatgaaggggacctggtctatctgaaggcatcccggtccatgaaattc
gaacgattcttaagtgtattggagaggatataa
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