Pseudomonas aeruginosa RP73: M062_11755
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Entry
M062_11755 CDS
T02711
Name
(GenBank) 2-oxoisovalerate dehydrogenase subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
prp
Pseudomonas aeruginosa RP73
Pathway
prp00280
Valine, leucine and isoleucine degradation
prp00640
Propanoate metabolism
prp00785
Lipoic acid metabolism
prp01100
Metabolic pathways
prp01110
Biosynthesis of secondary metabolites
prp01210
2-Oxocarboxylic acid metabolism
Module
prp_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
prp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
M062_11755
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
M062_11755
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
M062_11755
Enzymes [BR:
prp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
M062_11755
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
LutB_C
Motif
Other DBs
NCBI-ProteinID:
AGO39944
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Position
2517839..2519071
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AA seq
410 aa
AA seq
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MSDYEPLRLHVPEPTGRPGCKTDFSYLHLSPAGEVRKPPVDVEPAETSDLAYSLVRVLDD
DGHAVGPWNPQLSNEQLLRGMRAMLKTRLFDARMLTAQRQKKLSFYMQCLGEEAIATAHT
LALRDGDMCFPTYRQQGILITREYPLVDMICQLLSNEADPLKGRQLPIMYSSKEAGFFSI
SGNLATQFIQAVGWGMASAIKGDTRIASAWIGDGATAESDFHTALTFAHVYRAPVILNVV
NNQWAISTFQAIAGGEGTTFANRGVGCGIASLRVDGNDFLAVYAASEWAAERARRNLGPS
LIEWVTYRAGPHSTSDDPSKYRPADDWTNFPLGDPIARLKRHMIGLGIWSEEQHEATHKA
LEAEVLAAQKQAESHGTLIDGRVPSAASMFEDVYAELPEHLRRQRQELGV
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atgagtgattacgagccgttgcgtctgcatgtcccggagcccaccgggcgtcctggctgc
aagaccgacttttcctatctgcacctgtcccccgccggcgaggtacgcaagccgccggtg
gatgtcgagcccgccgagaccagcgacctggcctacagcctggtacgcgtgctcgacgac
gacggccacgccgtcggtccttggaatccgcagctcagcaacgaacaactgctgcgcggc
atgcgggcgatgctcaagacccgcctgttcgacgcgcgcatgctcaccgcgcaacggcag
aaaaagctttccttctatatgcaatgcctcggcgaggaagccatcgccaccgcccacacc
ctggccctgcgcgacggcgacatgtgcttcccgacctatcgccagcaaggcatcctgatc
acccgcgaatacccgctggtggacatgatctgccagcttctctccaacgaggccgacccg
ctcaagggccgccagctgccgatcatgtactcgagcaaggaggccggtttcttctccatc
tccggcaacctcgccacccagttcatccaggcggtcggctggggcatggcctcggcgatc
aagggcgacacgcgcatcgcctcggcctggatcggcgacggcgccaccgccgagtcggac
ttccacaccgccctcaccttcgcccatgtctaccgcgcgccggtaatcctcaacgtggtc
aacaaccagtgggcgatctccaccttccaggccatcgccggcggcgaaggcaccaccttc
gccaaccgtggcgtgggctgcgggatcgcctcgctgcgggtcgacggcaatgacttcctg
gcggtctacgccgcctccgagtgggccgccgagcgcgcccggcgcaacctcgggccgagc
ctgatcgaatgggtcacctaccgcgccggcccgcactcgacttcggacgacccgtccaag
taccgccccgccgacgactggaccaacttcccgctgggcgacccgatcgcccgcctgaag
cggcacatgatcggcctcggcatctggtcggaggaacagcacgaagccacccacaaggcc
ctcgaagccgaagtactggccgcgcagaaacaggcggagagccatggcaccctgatcgac
ggccgggtgccgagcgccgccagcatgttcgaggacgtctatgcagaactgccggagcac
ctgcgccggcaacgccaggagctcggggtatga
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