Pseudogulbenkiania sp. NH8B: NH8B_0168
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Entry
NH8B_0168 CDS
T01619
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pse
Pseudogulbenkiania sp. NH8B
Pathway
pse00300
Lysine biosynthesis
pse00550
Peptidoglycan biosynthesis
pse01100
Metabolic pathways
pse01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pse00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NH8B_0168
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NH8B_0168
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NH8B_0168
Enzymes [BR:
pse01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NH8B_0168
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF4996
Motif
Other DBs
NCBI-ProteinID:
BAK75017
UniProt:
G2IV51
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Position
189844..191205
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AA seq
453 aa
AA seq
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MLMLSDVAQLAGGRLAGADAEVTRVVTDSRAAGPGDLFVALKGEHFDAHDFVADVLAQGA
AGALVRQDFALPGAALVQVDDTRLALGRLAAGWRARFELPLVGITGSNGKTTVKEMLTAI
LAAHAGRDTVLATAGNFNNDIGLPLTLLGLNAGHRYAVIEMGMNHFGEIRYLTGLARPRV
ALVNNALRAHLGGGFSGTADIARAKSEIFEGLAEDGVAVINADDPHATIFRAAAAGHRLL
SFGLGEADVNARDVTLSDTAAHFVLCSPQGDVAVALPAPGEHNVRNALAAAAAALALEVP
LAAIAAGLAGFAGVKGRLQRKRAGNGATLIDDTYNANPDSMKAGIDVLLQALAPRWFVMG
DIGELGENAPALHAEVGAYARERGLDALLTLGDLSRHAAAAFGAAANHFDTLDALLSYLD
SHLPADATVLVKGSRFMRMERVVEHLTGQRQEH
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgctgatgctgtctgacgtggcgcaactggccggcggccgcctggccggtgccgatgcc
gaggtgacccgggtggtcacggacagccgtgccgccgggccgggcgatctgttcgtggcg
ctcaagggcgagcatttcgatgcgcacgatttcgtcgccgacgtgctggcgcagggcgcg
gcaggggccctggtgcgccaggacttcgcgctgcccggtgcggcgctggtccaggtggac
gacacccggctggcgctgggccggctcgccgccggctggcgcgcccgtttcgagctgccg
ctggtcggcatcaccggttccaacggcaagaccacggtcaaggagatgctgacggcgatc
ctcgctgcccatgccgggcgcgacacggtgctcgccaccgccggcaacttcaacaacgac
atcggcctgccgttgacgctgctcggcctgaatgccggccatcgctacgcggtgatcgag
atgggcatgaaccatttcggcgaaatccgctatctgaccgggctggcccggccgcgcgtg
gcgctggtcaacaacgcactgcgcgcccacctgggcgggggcttttccggcacggccgac
atcgcccgtgccaagagcgaaatcttcgaagggttggccgaagacggcgtggcggtgatc
aatgccgacgatccccacgccaccatcttccgcgccgccgccgccggtcatcgcctgctc
agtttcggtttgggcgaggccgatgtgaacgctcgcgacgtgacgctgtccgataccgct
gcccatttcgtcctgtgctcgccgcagggggacgtggcggtcgcgctgccggcgccgggg
gaacacaacgtgcgcaacgcgctcgccgccgccgccgccgcgctggcgctggaggtgccg
ctggcagccatcgccgccggtctggccggcttcgccggggtcaagggccggttgcagcgc
aaacgcgccggcaacggcgcgacgctgatcgacgacacctacaacgccaacccggactcg
atgaaggccggcatcgacgtgctgctgcaggcgctggcgccgcgctggttcgtgatgggc
gacatcggcgaactgggcgagaacgcgccggcactgcatgccgaggtcggcgcctacgcc
cgggaacgcgggctcgacgccctgctcacgctgggcgacttgagtcgtcacgccgccgcc
gccttcggcgccgcggcaaaccattttgatacgctggatgcgctgctctcctatctcgac
agccatctgccggcagatgccaccgtgctcgtaaaggggtcgcgcttcatgcgcatggag
cgggtggtcgagcatctgaccggacaacgacaagaacattaa
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