Pseudactinotalea sp. HY158: GCE65_10175
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Entry
GCE65_10175 CDS
T06271
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
psei
Pseudactinotalea sp. HY158
Pathway
psei00300
Lysine biosynthesis
psei00550
Peptidoglycan biosynthesis
psei01100
Metabolic pathways
psei01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
psei00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GCE65_10175 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GCE65_10175 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GCE65_10175 (murF)
Enzymes [BR:
psei01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GCE65_10175 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QGH69833
UniProt:
A0A5Q2W268
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Position
complement(2304328..2305800)
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AA seq
490 aa
AA seq
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MIALTPSLAAELLGATLEPGTPPTAAAELTDAVVDSRKVRPGSLFVALPGDHVDGHDYVA
TAHAAGAAAALVSRLVPGGGPQILVSDPAAALGTLARHHLAGLRERAAAAGRPFDVVAVT
GSVGKTTTKDLLAALLGELGEVVAPVASFNNEIGLPLTVLSAGEQTRTLVLEMGADAPGN
LTYLTSIAPPDLAIVLKVGRAHLQGFGSIEGVARAKAELVEGLRPGGVALLNLDDPRVAA
MAGLTEHVRTFGESPEADFRATHVRTDDDGRASFTLTGRAGGAAGATSPTEVSLALVGEH
HVVNGLAAAAAALLLGLSADAVAARLARTGPASAHRMHLIDTAGGIRIVDDAYNANPESV
RAALKALAAMSVRAGAGRERRRTIAVLGEMRELGPDSIGEHDAIGRLAVRLNIDKLLVVG
EGARPIHTGAVQEGSWGAEAAHVDTIEEALTVLLTELRPGDIVLLKSSNGAGLARLADRL
VADLAEVSAP
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcgctgacaccgtccctagccgccgagctcctcggcgccacccttgaacccggg
accccaccgaccgcagcggcggagttgaccgacgcggtcgtcgactcccgcaaggtgagg
cccggatccctcttcgtggcgctcccgggcgaccacgtcgacggccacgactacgtggcc
acggcccacgccgccggcgccgccgccgccctcgtgagcagactcgtgcccggcggggga
ccccagatcctcgtgagcgaccccgccgccgccctcggcaccctggcccgccaccacctg
gccgggctgcgggagcgggcggccgcggccgggcgccccttcgacgtcgtggccgtgacc
ggttcggtgggcaagacgaccacgaaggatctgctcgccgcgctgctcggcgagctcggc
gaggtcgtcgcccccgtcgcctccttcaacaacgagatcggcctgccgctcacggtgctg
agcgccggggagcagacccgcaccctcgtgctcgagatgggcgccgacgcccccggcaac
ctcacctacctcacctcgatcgcgccgcccgacctggcgatcgtgctcaaggtcggccgc
gcgcacctgcagggcttcggctcgatcgagggggtcgcccgcgccaaggccgagctggtc
gaggggctgcgccccggcggggtcgcgctgctcaacctcgacgacccgcgggtggccgcg
atggccggcctgaccgagcacgtgcgcaccttcggggagagcccggaggccgacttccgc
gccacccacgtgcgcaccgacgacgacggccgcgcgtccttcaccctgaccggacgcgcc
ggcggtgcggcgggcgcaacgagcccgaccgaggtgagtctggccctcgtgggggagcat
cacgtcgtgaacggcctcgccgccgccgccgcggccctcctactggggctgagcgcggac
gccgtcgccgcccgactggcgcgcacgggcccggccagcgcccaccgcatgcacctgatc
gacaccgccggcggcatccggatcgtcgacgacgcctacaacgccaaccccgaatcggtc
cgggccgcgctcaaggccctcgcggccatgagcgtgcgggccggtgcgggccgagagcgg
cgccgcaccatcgccgtgctcggggagatgcgcgagctcggcccggacagcatcggcgaa
cacgatgcgatcggccggctggccgtgcggctgaacatcgacaagctcctcgtggtcggc
gagggcgcccgcccgatccacaccggcgccgtccaggagggctcctggggggccgaggcc
gcccatgtcgacacgatcgaggaggccctgaccgtgctgctgaccgagctgcgccccggc
gacatcgtgttgctcaagtcctccaacggcgccgggctggcccggctcgccgaccggctc
gtcgccgacctcgccgaggtgagtgccccgtga
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