Polypterus senegalus (gray bichir): 120525468 Help Entry 120525468         CDS       T08668                                  Name (RefSeq) nesprin-1-like isoform X1   KO K19326   nesprin-1 Organism psex  Polypterus senegalus (gray bichir) Pathway psex04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:psex00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     120525468  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:psex03036]     120525468 Chromosome and associated proteins [BR:psex03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     120525468 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH Spectrin_Anc-1 DUF7648 P53_C Motif Other DBs NCBI-GeneID:  120525468 NCBI-ProteinID:  XP_039603723 LinkDB All DBs Position 3:109824579..110129810 Genome browser AA seq 8733 aa AA seqDB search MLLALLEVLSGQKLPCEQGRQLKRIHWVSNIGTALKFLEGRRIKLVNINATDIVDGRPSI VLGLIWTIILYFQIEELTSNLPLLQSLSSSTSSVDSLASSETASPPMKRKVLTKFQGNAK KALLKWVQYTAAKRLGIEVKDFGPSWRSGVAFHAVIYAIRPDLVDMDKVRRRSNRENLEE AFSIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDPHNTETDGHDEEREERR SLREMKAWLEQYERDLCRAQASEGSLQEKYQQFKGFRVQYEMKKKQIESLIQPVQKDGKL SVDQAVVKQALEKVYSVLLEWHIQLDNLLPGVLGTIGAWLHRAEISLREEISVQQAHEET ANNIHRKLEQYKEVLKSLEGQRQVFQQIHKTGSVNGVPVPKEQLDDMAERFNFVSTTSQI HIIKLEYLELKYRLLAFLMVAESKLKSWIIKYGRRESVELLLQNYTAFIEGNKFFEQYED TYQTMKQKADVYMKYDRSAEEIEGVSKFLCDTAAQWKNLSLEIRSVRSMLEEVISNWDKY SSTVANLQAWLEDAEKMLNQPENAKREFFRNLPHWIQQHTAMNDAGNFLIETCDETVSRD LKQQLLLLNGRWRELFVKVKHYARADEVDKIRKELQDGVAALKEFVDKANEKMTSPLEVS FLNVRTFTQDAEDIKQKLPIMEAQFKNVTRNAQILTKDTPEEEITLVQSTMTGIKDQLSK LRERYLPLLRESQSLLSPLEEMEKQITIFYQSLEKASCITAGRDGEIQAPGDFKQKCQDL INCQEDCKKCMTVIDRCNQTVQRIVTSSKTLEHFDRSLLQKRMADLQSSLKTMAVEATEW RKNIEANSSLMKRFEESRIELEKVLNIAQASLKEKGNPEELLKKHTEFFGHLDQRVLNAF LKACDEMTDILPENEQQSLQETVRKLHKQWKDLQTEAPYHLLHLKIEVEANRLKTSLEDC KLELSRENKLLPTVGSEQLIKEHKAFFGEKGPQNLCEKRLSLMEELCKKLPEKDPAYKNI ELSRKALTDITAQIEKTYQKLMQHPDKWKEFNTRFSELSAWLSSKESQLRVLRNRANDPG KYGQVSTTIEGLRGDVEQQEINLNWLKSRLSMLIEVSSESEGKRQDGALKKLSNDFKEFL SSLSETEKKVSAVGQCVHLQEEVKGILEELVQGQKEAEAESVRILDSESVQEAQQLLIIH QQNLKRLRSRRRDVQQQATRNQQLCADEGVATSLQPDLQELESTLSKMEQKMETQEKELQ VAVTDWHQFETDKEKMVQFLAKANSSLVKDLIFNSLESLNADLEESKNLLEVSEGQATYV DVLVKKSKEIKLGPKNTVLLQQQATSVQDQVNALEKHLHKDIKQMEKIKKEWEEFGQEYE DLSLWIAAKEKDLEPVNISTVPLDEQIGKVQDISKELEAKAKVIPSLEDKSVSLGQCVSS GEAARIKARLTQIGRHWEELKEQVQHLNGVLQENSSHLQKFQGSLIEVEKTLENLEDKLF SSVTSCSSATETHKELQKHGDLTLSLEPLRTTITSLLAGARKVTDKDKAEQNVISLQQRY EKDMQQAKQKQTKLENLLAMWQRFEKEWSTFESWLERCEAVIGTQAHLMSIDQAKLQSDL DTLKDLQHEVTSHESAYQTLSNLAASLYPTARENIVNEIKRNMKHTEERLYTLANAIPDR IQQVQSHITKIQEYDDSLLQLSNWIEQFLNSLQSTCEVNITDLQPTYNEIKNNLAELEKQ NAKKESLQAQVDILCSVCSPEDQDVLQSRKEDYFQLFREADQTLERRNEVLKQLEIFVQT HKRASGILHHLRKIVESANNWDKSKSESLQQELKDTVPQVSSLELLAVSVDGSLSKALYH IKEGDSEQRTSCRALADQLGTELELVQNILGTKQSEAEALTTLWASFKERKEQLLKSIED IEEKADNEGLREPTLLALQQRLRVFNHLEDELNSHQHEMQWLIDKAKQLMQKGADLVSEC KKEIVQVEKTWEATKSLIMENQEQCSVLIDLIREFQNRKSTINKIIESAENVAEIKSVLK DQEDIRRTLSRHEAIKNEMSAKQDELDAFNNKGKQVLNELKKIPTCDSTAVRKDMDAVVD QWLDVMDRIDENIERVSVCLSLWEDVLNITDEIDGWSNSSVSDLSENLSNLNNSQRMEER LVQFQLEIDNKEEKCKALNLKTTELKQLTKSQEPPTELQVLESDVRKKIIHARGVSDTAR ETLRQFSTQKQQLENFIAQMTEWLSSVEQSLLAFPHSIIPEDLQKVKDVQKNLQKQQGSI DMTRENLNGLCRKYHSNELEMLGGAITELIKKYEAVNQLSSKTLCALQDNLEQHFSDLVQ MFNSWLSERKDMVLECSDCSGDMNIIEEKLQKLKDVLNSMEEGEKRLALVCEEGEKLLLF LPKPSAIHIQQQLCVSQQEWDNFIEECKENQQALEESASQLTGFDSQLKKLNYWNQQMED QLNSDVLGERKPNISEKKSELEKVEKFHDQLLVKRESFDQLCQQSQSLSDQGLGDGREMR ATSQLQLSYQGLLKGAKERVRICQVAFQEHTVFEETLLSTWAWLKDVKGRLTVIDNTIGS KDLLEKRLIQVQEILLMKGEGEVKLNMAIGKGEQAMKSSSEEGQRAIRSKLQELKDVWAS VIMASMSCHSCLDWTVTQWTSFLEEKNQLQQWMDSVEQELSVPFQQQLGMKEKISQMERY RAILSDVENHASVLSRLEDKASEMLDKTGDASFERNEQIELRSQFHDINTVVKNKLKNLE EIVEEHKMYHEAIREFVDWLHSAKEELQRWSDMSGDSTCMQRKLTKIRELIDSRQNGKER LNRVQQSALNVKKNTAPSGCELIDRETVALLSDWQQWENNTLQTQGSLESVLSQMASSEQ EFITQANQLDCSLQQFSCSLKEWDQKLSQVSERNSNEEVLQGWRIAKDTFESLVKAETTS DSLKTQLNDLCRFSRDLSSHSERVSSLIKEYNSLCLRASKECQNKEKFLEQRFRLSFREF QQWLVSAKIATAKCFDVPQNIGEVTSSLLKIQEFLAERELGQCKMNAVVFNGEMICSILP TEKVETIQVKVTSAREDWKNLLSNLHQREAALQNLQSQMKDFEASAEPFQLWLNNTETAI QESSARLHSLSAKRQEQGKLQSVLEEIACQEFQLNRLKEKAQQLWEGQAAGKGFVHRVSQ LSAQYLALSNLTKEKASRIDRIVMEHQLFSQGLKELQDWVADANQMLQSYCSPTADKNVL DSRMLKLEALLAARQEKEIQLKMLLTRGESVQRNTSAEGVPVVRKQIQDLKDSWDSLLSA CIQCKSQLEASLSQWTSYQDDVRQFVSWMDKVEENLNSSEKQYPEMRDKTTNLGKAKLLH EEVLSHKSLLETITVKGSGMAEHYVTQLEIQELQERYSTLKEKAKASVTKAEELVLAHQE YQRGLRMFEDWLEQEQEKLSCFSHTEGDVETLENTLRELQDLQIQCTEGQALLNIALANR EKVIPRGIPQIEDRALETVEQEWDMYQARLAESRAHLNTTLTRLRQMEQKFQHLDEWLRN IETKATIRTGRRSDRATKEAQLQMLKGWHEETLMYKEEVEGASALAQQVLEETHINSRIS NRATQLTSRYQAVLLHLMETIKQLEEEIRSIEEAQIAFSSYTDWLGEAQKNFKNVAVSID VVNLIAMENKMKKLESLQSDMEVGHGFLKATREKAENAMTYLEQAEADELRQEVDAHLGQ LDELMGGIRTESSMLEKCMHVSKEFLDRYKIQAQWLLETRTMLNPPMEPKAELYEKKAQL AKYKGIQQTVLSHESSVKSVIEKGEALLDTVRDATVSENMKKLQEEYQDLCNIVRNHVQN LVTRVAEHELYNSDLQDIEKWLLQMSSRLVASDSMQSNSLEMATQQLARHKAIMEEIASS EDRLIKLKDKGDYIIGSCADHLQGKIKQQIQAHQQGTRDSYSAICSTAQRIYQGLDKELQ KHVSHQDTLQQCQVWLSTVRQELLLHTQAPFCLQDAWKQVKHYRALQEQASTYLDLVCSM CDLSDEDVRKTAADIQQIKQMVDERMARAQELAKGWQDIKQQKAELTSHFQDVEQQLQSL SRRPAELELKIAHNMLLQVQEFSQNLQSKQAIITQMTESVNRLANGQESSEHREISQLSN WWLELCNQVNKLLSQRECDLQRSRDYHDRISAVEALFDSVSKEWDNLIRTDAESTEEHLE ALQKLAATLEDQRYTLEDLKDHKQKVIDRLNLDEKELVKEQTGHFEQRWMHLESLIEKKI QDSVTTLEEMSQVIARLKDAREWAEEQQPALSEAMKLSPPPELAQSFLFDHLSICSELES KQMLLATAVTDADKVMTHLGLNERQQLQKLMTQVQGEIDSLKEMVNQRRKYLSKAFSEKT QFLLATHQAINWIQQNERKAISDEHIALLPEDLTKQIKTCRSVQSSLKAYQGELTSLWSQ GRGLMKDATEDEKEEVLSKLQELQNVYETALQRCTQRLQELEKVLVSRKYFKVDLDKTSQ WLKQADIVTFPEINLMNGDPELQSQLSKYQHVLDQATEYENLLLIVQRTGQEILPSLNEV DHAYLDEKLNALPQQFNHVLALAKEKREKIQQVILDRKEYSSFIEVTRKALQELEEQSNN MSKTPVGLESTALLNLKDDYQALLNEISGLGSAISELNQKKETFRSTGQPWLPEEMVQLV SLYSGLKRQIEQKLSDLDDTLESFREYEFMIQQLKNKLKAIKEEMGKVNEETLPAEDKLK KYHTLAGNAQDASSVLKCIVEQLEHLSPHVDSESYQSSSRQIIAWQEELKVLHTKVAERM EESESRFVQSKDFQTEICRSLEWLQQIRNDQTSLQGFDIKIQSIQEEIRKQQILQEEVQS RLRIMAALSNKEKQKYTDAKELVPAVLEATLQELANLETEVRNILSTKQTKLQQVLDLFQ KYHSATQSANNWLEEASALLQESSPGLDVELSEDLLHHLTEFTTSEAQFHDHLHVLESLI SQLRPFLSEGVNDQVAQNVSSLQQKGEAVHRQIQSQEELLNRSLSQWHVYQTCRQQLIEH MNELEKKLTEFSTARVAISHEAELKLKSHKSLVSMVNALHGKITALEEQASKMEQIGNDA SKATISRSMTTVWQRWTRLRNVARGQEKVLEDMAQEWRSFNDKMEKATVTMHQLQDRMPD SSVEKISKAALLELMDYHDSFSQETDRELSATTLLRQHAFSILQDVEFSSPSQEELPSMQ EIKAMQERYESILQKVKKSRKHVQQELKEREEVEKELNKVKAWIQDTREYLLNPTVDIEG QLQELEVLQQEAISHRQAVEKTAEQQQNKYLDLYTILPSELSVQLAEVTLALGVTEDQIQ VKEREVQQARIVNEDIKSRIQDVSEKMKAISLKLKEKTLNIAQAKEETKCLCEELEGCSI ILLELDASVQDFSEQCPELARHLNDAIEKLTDIHLHTRRLADYRVAKLKKSATHLDEFNE MLEFILKWTEKAKALVKSKINWNSASRIYDQMRTYQAVLQESGEIHSDLEAMSEKAECLL EVYDTEEMSQQVSELSRHTGQLQQRIRTRLQSLQDGGKDMERFEAEVHALHNALEQAQTT LTSPDLARLSLKEQLSHRQRLLTEMETFKQKAQAVQMCQSALRIPEEVVTNLPICKTALR LQDEASRLQHTTIQQCNILQEAVVQYEQYEQEVKLLQGLIEEAHRVIQDRPVTTSSIQEL QAQISHHEELAQKIKGYQKQIDSLNSKCKMLTMKAKHAAMLLTVTEVEGLSEGYDELDAE LLPAQSLAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVN QLQTAAAKSQPTVTSGQEISEAGLESAAVAKLDDLQRSWETLKNVISEKQRTLYEALERQ QKYQDSLQSVSTKMESVEIKLNETLEADKTPESQMAAHRALMDEILMLQDEINDLQTCFS EEMTCDAPDMDTADQLAMQSTLTVLAERMSTIRMKASGKRQLLEEKLSEQLEEQRQQQAL QRYHSEADELDLWLHSTKASLKSALQSSDEHMDMEDQLIDCQNMLMEIEHKVASLSELSV HSENLLMEGKLHSRQEAEQLSHKLRTLKGSLLELQRMLQDKQINIQQGPRLEKEESERNS SLSQSPSVQEWLVQARTSRSQKHQDSLKRQRELEQQLAQQKELLQSVASRGEQILTQQSN KSDKPKSLSEEFDLEEEKPSAQEQMRMRWESLNRELDTKQKFLENTLEQDQNQPVYSRPS LVSSSTPMFKGDAPAQDKSSVKSLFSRFTQACDDVQFQMGGADKQSLHLEQKLYKAVSAT SNWLDGVENSLFTGPVLLAEDTETQLCNQEGLGKDIKEVTEDVDKNKELFLQELARCGEN QDVIEETLGHLQVRLGALDSAVSQKCNDMKIRLQQLTEFQTEMKLLFSALADSKYQILQK LAAAMERPATNLMEAISQAEESMKEFEQRIIELKVQGEKLQLDQPSVQELLKLQDTYEEL VMTVGSRRSGLNQSLALKDQYAQALQDLSDLVDTAQEKIASSQKIIANSKVDIVNLLEKH KDFFQGLESHMILTETFHRKISGFLLPRESQSYEETMNHASVVLKQAHKRGIELEYILET WIHLEDDYQSLFRQLELVESNVPSVGLVEETEERLLERITIYQHLKSSLTEHQHQLYQVL DDGKRLMMSVCCSDLDIILTQLGERWLNNTSKVNKELNRLDTILKHWQRYQRESTELGQW LQNALDQLEYWNTQSVTVPQELETVRDHLSTFLEFSKIVDAKSSLKSSVLSTGNQLLRLK KVDTAGLRAELSQIETRWAELLTSIPAVQEKLHQLQMEKLPSRHAITELMSWISLMEHVI KEDEEKIKGVVGSEAIKGYLQKYKGFKIDINCKQLTVDFVNQSVLQISGQDVESKRSDKT DFAERLGAMNRQWQILQGLITEKIQMLENLLDSWLEYESNVQSLQTWFGVQEDRVKKHYR IEDLASVQNTLKDCQELEEMIRVKERDVEKVEERGYTLIQNKKEGACTVVMETLQGVNHS WANLDHLIGQLKISLKSVLDQWNIYKKTLEEINGYLMEGRYSLSRFRLLTGSLEAVQIQV GNLQNLLDDLEKKENIKRKFGSVTHQLLKECHISVADSLNNALKDVELRWTCLLVDISEQ LHTSKALLKLWQRYKEYYNQSSSSVLQQEELANELLKKATGKDISDEEISSWIQDCNDFL RSQNAVQESLGVLHELGEQLKQQVDSSAVAAIQSDPLSLTQRLTVLEQALIRQKGILQAG VLDYETFNKQLQELENWITEAQDILKDQDPNCSSDLSIIEDRMEELKRQMLKFSSMAPDL ERLNELGYRLPLNDKEIKRMQTLNRSWSVTSAQTTERFSKLQAFLLQHQTFLEKCETWMQ FLMQTEEKLAVEISGNFQSLLEQQRAHELFQAEMFSRQQILHSIISDGHRLLEQGQVDDR DEFNLKLALLSNQWQGVIRRAQQRRGIIDSLIRQWQRYREMAEKLRKWLLEVSHQSENKQ DGTPVPLQQARAMLDEIQLKERVLQRHQGSYILTVEAGRQLLLSADTEAEMTLQAELTDM QERWKCANVRLDERKRELSVLLKNWDRCEKGISDSLEKLRAFKKKLSQPLPDHHDELHAE QIRCKELENTFDGWTDDLAHLSVLKESLSSYISADDLTVLQERIELLQKQWEELSHQLSL RWQQVNEKLNEWAVFNEKNKELCEWLTQMESKVSQNGDISIEEMIEKLRKDYQEEITMSQ ENKIQLEEMGERLAKVSHESKASEIDYKLGKVRDRWQHLLDLIGARVKKLRETLVAVQQL DKNMGSLRSWLAHIETELSKPIVYNTCNLSEIEKKLNEQQELQRDIEKHSTGVASVLNLC EVLLHDCDACATETECDSIQQATRSLDRRWRNICAMSMERRLKIEETWRLWQKFLDDFSR FEDWLKMSEKTAAIPNSSGVIYTVAKEEMKKFEAFQRQVHESLTQLELINKQYRRLAREN RTDSSCKLKQMVHDGNQRWDNLQKRVASILRRLKHFISQREEFETARDSILVWLTEMDLQ LTNIEHFSECDVQAKIKQLRAFQEEIALNRGKIDHIFQQGELLIEKNEPLDAAVIEEELE EVQRYCDEVFGRVERYYKKLMRLPLTDDEHDVSDRELDLDEATELSSLHWNDKPTDSILS PQAGSSRSTSMAPPTRTERSGRDTPASVDSIPLEWDHDYDLSRTLEPLSPLQAAGISDDG EDGQDKGEKELFLHGASSLSDVVIPENPEAYVKLTENTLRSISGACGSLETHIRQLDKAL DASRFHLQQTENIIRSRTPTGPELDSTYKGYMKLLSECRESIDTVKRVGCNLKEDEDHFS GFINLNGTETQTSGVIERWELIQAQALNKELRMKQNLQHWQQFNSDLNNIWDWLGQTEEE LEQLRGLKLSTDIGTIEQHIKKLKELQKAVDNRKAIILSINLCSSEFVQSNTEEAQELQT RLGQMNKKWDRVGVLIEEWRVSLQDALMQCQDFHEMSHGLLLWLENIDRRRNEIVPIQPN LDSDTLHDHHKILMQIRQELLESQMKVVSLQSMSSQLLVNAVGADCLEANEKVHVIGNRL KLLLKEVTQDLRDLEKLLDIRSSQLDLSSWSSTDELDTSGSLSPASGRTTPSRRRSPRGK CSLSQPGSSVSSPHSRPHRSDGSGSSHSETQHSQSFFLRVLRAALPLQLLLLLLIGLACL VPMTEEDYSCALSNNFARSFHPMLRYTNGPPPI NT seq 26202 nt NT seq  +upstreamnt  +downstreamnt atgcttcttgccttgcttgaggttctttctggacagaaattgccatgtgagcaaggccgg cagctgaaacgaatccactgggtctccaacattggtactgccctgaaatttctggaggga agacggatcaaattagtcaacattaatgcaactgacattgttgatggacggccttccatt gtactcggcttgatttggaccataattctgtatttccagattgaggagttgacaagtaat ctacctttacttcagtcattatccagcagtacgtcatctgtggacagcttggctagctca gagacagctagtcctccaatgaaaagaaaagttctcacaaaattccaaggaaatgctaaa aaggctctgttaaaatgggtgcagtataccgcagcaaagcgcctcggaattgaggtgaaa gattttgggcccagctggaggagcggagttgcctttcatgctgtgatttatgcaattcgt cctgacttggtagatatggataaagtaaggaggcgttcaaatagagaaaacttggaagag gccttttccattgcagaaactgagctaggaatcccccgactgcttgatccagaagatgtg gacgttgacaaaccggatgaaaagtccattatgacatatgtggcccaattccttaaacat tatccggacccacacaacacagagacagatggccatgacgaagagagagaggaaagacgt tccctgcgagaaatgaaggcttggctggagcaatatgaaagggatctctgcagagctcaa gcatctgaggggagcctgcaggaaaaataccagcaatttaaaggttttcgagtacagtat gaaatgaaaaaaaagcagattgagtccttaattcagcctgtacaaaaagatgggaagttg tcagttgatcaagcagttgtcaagcaggcgctggagaaagtatattccgtgttgctggaa tggcatattcagcttgataatttgctgcctggagttttgggaacaattggtgcctggcta catcgggctgaaatttccttaagggaagaaatatctgtgcagcaggcccatgaagaaacc gcaaataatatccacagaaaactggaacagtacaaggaggtactaaaaagtcttgaaggc caaagacaggtatttcagcagatccacaagacaggaagtgtgaatggagtaccagtccca aaagaacaattggatgatatggctgaaagattcaattttgtttcaacaacatcacaaatc catataattaaactggaatatttggagctaaaatataggctcttggcttttctgatggtg gcagaatccaagctgaagtcatggatcatcaagtatggtagaagagaatcagtagaactt ttgcttcagaattatactgcattcattgaaggaaataaattctttgaacagtatgaggat acatatcaaacaatgaaacagaaagctgatgtctatatgaaatatgacagatcagctgaa gaaattgaaggtgtgagcaaatttctatgtgatactgctgcacaatggaagaatttgtca ttggagattcggagtgtgcgtagcatgttggaggaggtgatttccaactgggacaagtac agcagcactgttgccaatttacaagcatggcttgaggatgcagaaaaaatgttgaaccaa ccagagaatgccaaacgggaattcttcagaaatttgcctcattggattcaacaacacaca gcgatgaatgatgctggaaattttcttattgaaacatgtgatgaaactgtgtcacgagac ttgaaacagcaattgcttttacttaatggaagatggagagagctatttgtgaaagttaag cattacgcacgcgctgatgaagttgataaaataaggaaggaactgcaagatggagtggct gctttaaaagaatttgtcgataaggcaaatgaaaaaatgacctctcctttggaagtatcg tttctaaatgtacggacctttacacaagatgctgaggatattaaacagaaacttcccata atggaagcccagtttaaaaatgtcactagaaatgctcagatacttacaaaagatacacct gaagaggagatcacccttgtgcaatcaacaatgacaggaattaaggatcagctgagcaag ctaagggaaagatacttgccattgctgcgtgaatctcagtcacttctttctcctctggag gaaatggagaaacagataacaattttttaccagtctctagagaaggctagttgcatcact gcaggcagagatggtgaaattcaggcccctggagacttcaaacagaaatgtcaggacttg attaattgtcaggaggactgtaaaaaatgtatgacagttattgacagatgcaaccagact gtgcaacgcattgttacaagcagtaagacacttgaacactttgaccgttccctactgcag aaaaggatggctgatctgcagagttcattaaagactatggcagtagaagccacagaatgg agaaaaaatattgaagctaacagcagtctaatgaaaagatttgaagagtctagaatagaa ttggaaaaagtgttgaacattgcacaagcatctttaaaggaaaagggaaaccctgaggag cttctcaaaaaacatactgagttttttggccacttggatcagagagttctgaatgcattt cttaaagcctgtgatgagatgactgacattcttcctgaaaatgaacaacaaagtctgcaa gaaacagttagaaagctgcacaagcagtggaaggatcttcaaactgaagcaccttatcat ttactacatttgaagattgaggtggaggccaaccgtcttaaaactagtctggaggactgc aagttagagttatctcgagaaaacaagttactccctactgttgggagtgagcagcttata aaggagcataaggccttctttggagagaaagggccacagaacctgtgtgaaaaaagactc agtttaatggaagaactttgtaaaaagcttcctgaaaaggaccctgcctacaaaaatata gagctcagccggaaagctttaacagatatcacagcacagattgaaaagacctaccagaaa ctaatgcagcatccagataagtggaaggagtttaacaccaggttttctgagttatctgcc tggctgtcttcgaaagaaagtcaattacgggtgttaaggaacagagcaaatgatccaggc aaatatggacaagtcagcacaactattgagggactgcgaggagatgtagaacagcaggag attaacctaaactggctgaaatcaaggctttcaatgctgatagaagtttcctctgagagt gaagggaaaagacaagatggcgctctaaagaaattgtcaaatgactttaaggaatttctg tcttcacttagtgagactgagaagaaggtctcggctgtaggtcagtgtgttcatcttcag gaagaggtaaaaggcattctggaagaacttgttcaaggacaaaaagaagccgaggctgag tctgtcaggattcttgattcagaaagtgttcaagaggctcagcagcttcttattattcac cagcaaaacctaaaaagactgagatcaagacggagagatgtccaacagcaagcaacacga aatcagcaactctgtgctgatgaaggagttgccacttctctgcaaccagatcttcaagag ttggaaagtactttaagtaaaatggaacaaaagatggaaactcaggagaaggagctacag gttgcagtgaccgattggcatcagtttgaaacagataaagaaaaaatggttcagttccta gcaaaagcaaactccagtttagtaaaagacctaatattcaacagcctggaaagccttaat gcagatctggaggaatccaagaatcttctggaagttagtgaagggcaagcaacttatgtg gatgttcttgtcaagaaatctaaagaaattaaacttgggccaaaaaatacagttctttta caacaacaggcaacctctgttcaagatcaggttaatgcattggaaaaacatttacataag gacattaaacaaatggaaaagattaaaaaagagtgggaagagtttggtcaggagtatgaa gatctttcgctgtggattgctgcaaaggaaaaagacttagagcctgtaaatatttctact gtgccacttgatgaacaaattgggaaagttcaggacatcagtaaagaacttgaggccaag gctaaagtaatcccgtctttggaagataagtctgtgtccctggggcagtgtgtatcttct ggagaagctgcacgcataaaagccagattgacgcaaatcggcagacactgggaagagctg aaagagcaagtgcaacatctgaatggagttttacaagaaaattcctcacacttacagaaa tttcaaggcagccttatagaggttgaaaagactttggaaaatttagaagataaattattt tcctcagttacgtcttgttcttctgccacagaaacacacaaagagcttcagaaacatggg gacctcacactctccttagagccactgaggaccacaatcacatcgctactggcaggagct cgtaaagtcaccgataaagacaaagctgagcagaatgtcatttccttgcagcaacgctat gagaaagatatgcagcaagcaaaacaaaaacaaactaaactggaaaacctccttgcaatg tggcaacgatttgaaaaagaatggagtacctttgagtcctggctcgagagatgtgaagca gtaattggcacacaggcacatctcatgtctattgatcaagcaaagcttcaaagcgatctt gacactttaaaggatttacaacatgaagtgacatcccatgagtcagcatatcagacactt tcaaatcttgcagcttccctttaccccacagccagggaaaacatagtgaatgagataaaa cgcaacatgaagcacactgaagagagactgtataccctggcaaatgctataccagataga atccagcaagttcagtctcacattacaaaaatccaggaatatgatgatagccttcttcag ctgtcaaactggattgaacaattcctgaacagtctccagtccacttgtgaagttaacata acagatctccagccaacatataatgaaattaaaaacaacttggctgaacttgagaaacag aatgcaaagaaagaaagcctacaggcccaagttgatatcctatgctctgtctgcagtcct gaagaccaagatgtcttacagagtaggaaagaggattattttcagctcttccgtgaagca gatcagacattggaaaggagaaatgaagtactgaaacaactagaaatatttgtacaaaca cataagagagcatctggtatattacatcatttaaggaagattgttgagtctgcaaacaat tgggataaaagtaaaagtgaatccctacagcaagaattgaaagatacagttccccaagta agcagtttggaactattggcagtcagtgtggatgggagtcttagcaaggctctttatcac attaaagaaggtgattctgagcagaggacctcttgcagagctttagctgatcaactgggc 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tgtcagaacatgctgatggagattgagcacaaggtggcctccctgtcagagctgtcggtg catagcgagaacctgctgatggaggggaagttgcattccaggcaagaggcagagcagctt tcccacaagcttcgcaccctcaagggcagccttttggaactacagaggatgctgcaagac aagcaaatcaacatccaacagggtccacggctagaaaaagaagaaagtgaacgcaactca tccctgtctcagagccccagtgtccaggaatggctagttcaagcaaggacatcaaggtct cagaaacatcaggacagtctgaaaagacagagggaactggagcagcagctggcacaacag aaggagctcctgcagtcagttgcaagccgaggggaacagattctgactcaacaaagtaac aagagtgacaaacctaagtccttatcagaagaatttgatttggaggaggaaaagccttct gcacaggaacagatgagaatgaggtgggagagtctaaatagagaacttgataccaagcag aaatttttggaaaacactttggaacaagaccagaaccaaccggtttatagtcgacctagt ttggtgtcttcttccacaccaatgttcaaaggagatgctccagcacaagacaaatcatct gtaaaatctttattcagtcgttttacccaggcctgtgatgatgtccaattccagatggga ggtgctgataaacaaagtcttcacttggagcaaaagctttacaaagctgtatctgctaca tccaattggttggatggtgttgaaaacagtcttttcaccggaccagttctccttgctgaa gatacagagacacaactttgtaatcaagagggattaggcaaagatatcaaggaagtaaca gaagatgtagacaagaataaagagctcttccttcaggagctggcacggtgtggagaaaac caggatgtgattgaagaaactttgggccatcttcaagtacgtcttggtgccctagactca gctgtgagtcagaaatgtaatgatatgaaaatacgcctccagcagctaacagagtttcaa acagagatgaaactgttattctctgcattggctgatagtaaatatcagatccttcagaaa ctagcagctgcaatggagagaccagctacaaatctgatggaggcaatctcacaagctgaa gagagcatgaaggagtttgagcaaagaattattgagcttaaagtacaaggagagaagcta caattggaccagccttccgttcaggaacttttaaaacttcaggatacttatgaagagctt gtcatgactgttggctctcgcagaagtggactaaaccaaagcctggctctgaaagaccag tatgcacaggccttgcaagacctctctgacctggtggatacggctcaagaaaaaattgct tccagtcaaaaaattatagccaactccaaagtggatattgtgaatctccttgaaaagcat aaggatttttttcagggtttggaatctcacatgatcttgacagaaacgttccacagaaaa atcagtggttttcttctaccaagggaatctcagtcttatgaggaaacaatgaatcatgcc tctgtagttttaaaacaagcccataagagaggcatagagctggaatacattcttgagacc tggatccaccttgaagatgattaccagtctttgttcagacaactggagcttgtagaaagt aatgtccccagtgttggtctagtggaagagacagaagaaagacttttggaaaggataaca atttatcagcatttgaagagcagtttgactgagcatcaacatcagctctatcaggttttg gatgacgggaagaggctaatgatgtctgtctgttgttcggatttggatattattttgact cagctgggggaacgctggcttaataatacatccaaagtaaacaaggagctcaacagactg gacacaatattgaaacattggcaaaggtaccaacgagagtctacagaacttggacaatgg ctgcaaaatgcacttgatcagctagagtattggaacacacagtcagtaactgtaccacag gagctagaaactgtgcgagaccatctcagtacattcctggagttctcaaaaatagtggat gccaaatcttctttgaagtcttcagtattgagtactggtaatcagttgctgcgtttgaaa aaggtggacacagcaggactgcgggctgaactttctcagattgaaactcgctgggctgaa cttcttacaagcattcctgcagtgcaagagaaactacaccagctccagatggagaaactt ccttctcgtcatgccattactgagttgatgagctggatttctctcatggagcatgtcata aaagaagatgaagaaaaaatcaaaggtgtagttggatctgaagctataaaaggatacctt cagaaatacaagggtttcaagattgatattaactgcaaacagcttacagtggattttgtt aatcagtctgtccttcaaatcagtggtcaagatgtggaaagtaagcgcagtgacaaaact gattttgcagagcggcttggagcgatgaataggcaatggcagatattacaaggtctaata acagaaaagatccaaatgttggaaaatctgcttgattcctggctagaatatgagagcaac gttcagagtttacagacttggtttggtgtgcaagaagacagagttaagaagcattacagg atcgaagacctggcatctgttcagaatacattgaaggactgccaggagcttgaggagatg attagagtgaaggagcgagatgtggagaaagtggaagagagaggctacacactgatacaa aacaagaaagaaggtgcctgtaccgttgtaatggaaacattacaaggggtcaatcatagc tgggctaacctggaccacttgattggacagctaaagataagtttaaaatcagtcttggac caatggaacatttataaaaagacacttgaagaaatcaatggttacttaatggaaggaagg tactccttgtctcgattccgcctgctgactggttctttggaagctgtccagattcaagtg ggcaacttacagaatctactggatgatcttgaaaaaaaggaaaacatcaaaaggaagttt gggtctgtgactcatcagctgctcaaagagtgtcacatatctgttgctgactccttaaac aatgcactcaaggatgttgaattgaggtggacatgcctgcttgtggacatttcagagcag cttcatacaagcaaagccttacttaagctgtggcaacgatacaaggaatattataaccaa agctcttcatcagtcctacagcaggaagaacttgctaatgagctgttgaaaaaagccacc ggcaaagacatttctgatgaagagatttccagttggatccaggattgtaatgatttcctg agatcccagaatgcagtgcaggaatccctcggtgttctccatgaacttggtgaacagctg aaacagcaggttgactcatctgctgttgctgccattcagtctgatcccctctccttaaca cagcgcttaacagtactggagcaggctctgatccggcagaagggaattctccaggctggt gttctggactatgagacatttaacaaacagctgcaagaacttgagaattggataacagag gctcaagatattctgaaagaccaggatcccaactgttcatctgatctgtctattatagag gacagaatggaggaactcaagaggcaaatgcttaagtttagcagcatggcaccagatttg gaacgcttgaatgagcttggctacaggttgccactgaacgacaaggagattaaaagaatg cagaccttaaacaggagctggtcagtgacctccgcacaaaccactgaacgatttagtaaa ctgcaggcttttctattgcaacaccaaacattcctggagaaatgtgagacttggatgcag ttccttatgcagacagaagagaaactggctgtggaaatatccggaaactttcaaagtctt ctagagcagcagcgtgcacatgagttgtttcaagctgagatgttcagtcggcaacagatt ctgcattctatcatcagtgatggacaccgccttctagaacaagggcaagtagatgacaga gatgaatttaacctgaaattggctctgctgagtaaccagtggcaaggagtaattcgcaga gctcagcagaggaggggaatcattgacagcttaattcgccaatggcagcgatatagggag atggcagaaaaactccggaagtggctgctcgaagtgtcacaccagagtgagaacaaacaa gatggtacaccagtgcctctgcagcaggccagagcgatgcttgatgaaattcagctgaaa gaaagggttttacaacgtcaccagggaagctacatcttgactgtggaggcaggaagacag ctcctgttgtcagcagacacagaagcagaaatgactctccaagcagaactaactgatatg caagaacgctggaagtgtgcaaacgtccgccttgatgagcgcaagagggagctgtccgtt ttgctaaagaactgggatcgctgtgagaaggggattagtgattcactggagaaattacga gccttcaagaaaaagctttcccagcccttgcctgaccatcatgatgaactgcatgctgag cagatccgctgcaaggaattagagaacacatttgatggttggacagatgacctggctcat ctctctgtactgaaggagtctctatcaagctatattagtgctgatgacctgacagtgctc caggagcgcattgagcttttgcagaagcaatgggaagagctcagtcatcagctttccttg cggtggcagcaggtgaatgagaagctgaatgaatgggccgtattcaatgaaaagaacaaa gaactctgcgagtggcttacacaaatggaaagcaaggtttctcaaaatggtgacattagt attgaagaaatgattgaaaaacttagaaaggactatcaggaagaaataacaatgtctcaa gaaaataagatacagcttgaggaaatgggagaaaggcttgcaaaggtcagccatgagagt aaagcttcggaaatagattataaactgggcaaggtcagagatcgctggcaacacctttta gacctcattggagccagggtaaagaagctcagagaaacgcttgtggctgtacagcagttg gataagaatatgggcagcctaagatcatggcttgctcacatcgaaacagaactttcaaag ccaatagtctataacacatgcaatctcagtgaaatagagaagaagctcaatgagcaacag gaactacaaagagatatagagaagcacagcacaggggtagcctcagttcttaacctttgt gaggtccttctgcatgattgtgatgcttgtgctactgaaactgaatgtgactccatccag caagccactcgtagcctggacagaaggtggagaaacatctgtgccatgtccatggagcgg agactcaagattgaagaaacctggaggttatggcaaaagttccttgatgacttttctcgt tttgaagactggcttaaaatgtcagagaagactgcagccatccccaactcttctggagta atttatactgtagccaaagaagagatgaagaagtttgaggcatttcaacgacaggttcat gagagcttgacacagctagagcttatcaacaagcagtatcgccgtctggctcgagagaat cgcacagactcttcttgcaagctcaaacagatggtgcatgatggcaatcaaagatgggac aatcttcagaaaagagtagcctctattttgcgaaggctaaagcactttataagccaaagg gaagagtttgagacagccagagacagcatactggtgtggctcacagaaatggaccttcag ttaacaaatattgagcatttctcagaatgtgatgtccaagccaaaataaaacagctcagg gcattccaagaggagattgcactaaacagaggtaaaatagaccatatattccaacaaggt gagctgctgattgagaaaaatgagcctttagatgctgctgtcattgaggaagagttggag gaagtacagcgatactgtgatgaggtgtttggacgcgtagaacgctactacaagaagctt atgcgacttccactgacagacgatgaacatgatgtctcagatcgagaactggacctggat gaggccacagaattgtccagcctgcactggaatgacaagcccacagatagtatcctctct ccacaagcaggttccagtcgttcaacttctatggcccctccaactcgtacagaacgttca ggtagagacaccccagctagtgtcgactcaatcccacttgaatgggaccacgattatgac ttgagtcgtactctggaacctctgagcccactacaagcagcaggtatttcagatgatggc gaagatggccaagataagggtgaaaaagagctcttcctccatggtgcttctagcctgtca gatgtagtgatccctgaaaacccagaggcatatgttaaactgacagaaaatacattgcga tcaatctctggtgcctgtggctctttggaaactcatatcagacagctggataaagcgttg gacgcaagtcgtttccacctgcagcagactgaaaacatcatccgaagccggacaccaaca gggccggagcttgactccacgtataaaggatatatgaagctgctgtctgaatgcagagag agcattgacacagtcaaaagggttggatgtaatctaaaggaagatgaagaccatttttca ggatttatcaacctgaacggcacagagacacagacctcaggtgtgatagagcgttgggag ttgatccaggcacaggctctcaacaaagagctcagaatgaagcagaatcttcagcattgg caacagttcaactctgacctgaacaacatctgggattggctgggccagactgaggaggag cttgagcaactgcgaggcctgaaactcagcactgacattggcaccattgagcagcatatc aagaagctgaaggaactacaaaaagctgttgacaatcgaaaagccatcatcctctcaatc aacttgtgcagctctgaatttgtgcagtcgaacactgaggaggctcaagagctgcagacc cgattgggacaaatgaataagaagtgggaccgtgtgggagtgttaattgaggagtggcgc gtctcactgcaggatgcccttatgcaatgccaagattttcatgaaatgagtcatggactg ctgctatggttagaaaatattgaccggcgaagaaatgaaattgttcccattcagccaaat ctagactcagatacccttcatgaccaccacaaaattctcatgcaaatcagacaggagtta cttgaatctcagatgaaggtggtctccctacaaagcatgtccagtcaattgctggttaat gctgtgggagcagattgcttggaagccaatgaaaaggtacatgtcattgggaaccgactc aagcttcttctgaaggaagtcacacaagacctgagagacctggaaaagttgttagacatc agaagcagccaattggatctatcttcttggtcatcaactgatgaactggacacttctggt tccctgagccccgcatctggcaggaccactccaagtcgacgtcgatcgccacggggcaaa tgtagtctctcacagcctggatcctctgtcagcagtccacacagcaggcctcacagaagc gatggatccggttcttcccattctgagacccagcactcccagtccttcttccttcgtgtg ctacgagctgcgctgcctcttcagctgctgctactcctacttattgggttagcctgtctt gtgcccatgacggaagaagactacagctgtgcactgtccaacaactttgcaagatctttt caccccatgctgcgatacactaatggaccaccaccgatatga

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