Polypterus senegalus (gray bichir): 120533956
Help
Entry
120533956 CDS
T08668
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
psex
Polypterus senegalus (gray bichir)
Brite
KEGG Orthology (KO) [BR:
psex00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
psex01001
]
120533956 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
psex04131
]
120533956 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
psex04147
]
120533956 (lrrk2)
Enzymes [BR:
psex01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
120533956 (lrrk2)
Protein kinases [BR:
psex01001
]
Serine/threonine kinases: TKL group
LRRK family
120533956 (lrrk2)
Membrane trafficking [BR:
psex04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
120533956 (lrrk2)
Exosome [BR:
psex04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
120533956 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
WD40_2
Arf
Beta-prop_RSE1_2nd
Gtr1_RagA
WD40_CDC20-Fz
Kdo
MMR_HSR1
Septin
T2SSE
PduV-EutP
AAA_22
TrwB_AAD_bind
ABC_tran
Ank_2
MobB
DLIC
GTP_EFTU
Beta-prop_EML_2
Beta-prop_WDR90_POC16_2nd
AAA_33
NACHT
AAA_16
AAA_7
AAA_29
Motif
Other DBs
NCBI-GeneID:
120533956
NCBI-ProteinID:
XP_039617043
LinkDB
All DBs
Position
8:57189450..57437154
Genome browser
AA seq
2511 aa
AA seq
DB search
MKRMACKDNREEQLKKLIVRLKNTQEDKPIETLIQILEDLLFLTFAEDRVEEHFADKQLH
DPLSTVLKTFIDNAGVQQVGWSLLCRLIEICPSTLDKLSASKNVSSIHMQILRILAVHSG
HVKLMMIGLRALSLLLYSDAIVLLTLDDEVDVFYLIVSAMNTFCFNEEVQLYGCKSLQLL
LERVADEHLIEFVETGDHMAILNTIKQFQNNEDTVLQALKALLPLAGPISNVEVLMSGNE
RCYSLIMSAMESFSKNEKVQEIGCCLFQKFTSESFHNILVLNGVHKFIIKAAMMYQTNAK
LQASALMCLASLTETIVLNKDLNEYKEEDDLCWIDVCCRALDLHIGSKEVQAATCWALNN
LLVYESKLHEMFGDEDGRYPVHLQVMAAMLLHSSSKEVFQATANTLATMAGQNVKIRSVL
LSSGIHINIFELMKKHIGFPEVAESACRLLYNLFQVNVACLDVATMAMAEILNAMKVHKC
SPSVQLEALRAALLFVSSDKSGKTKMSLQCDIEESDMINVTLKVIKNQCVLEGAHTLVLD
TLNKFIGSPVIQDCGLRVLCSLVDCSGALELMSQQGAIDTILHTLQMYPDEKEINWLGLN
LLCCLFPKKKLSLGTIAILCSVLVKSLLRFREVLEVQLWGFRAVLALLETSPASAEQLER
ESFDLFIFQQVNFSPLEERFNQMQKLYCMCLSILATDGEIRHRMLEKACAEDNFVMAECL
IHLGADVNKKTKNESLIYKVCEKECSSELVELLLNSGTHEQDIRKALFISVKKRNNLIIS
LILRKLGLDQANSAICLGGFRLGHLESSWLNPLFSERKTLNFRQQTSKGMSLVRVIMKYQ
KQRNLSKSVTSNLDTFGSGYMSDEADDSGFVTEGSSVFMNEDIESDESSGIFYRLKKIQS
DSVTESSSLRHRRSRRPSSEVEIAESEPNPLFQMKYLKASTSQRSKYTSPSRSPELSSLL
GIEKECIKLLDLSGNDLDNVNAFCGKTTLNCYLEQVQRLELHHNNLLEFPEKICEVMKHL
THLDLHSNRFTIFPFYMMKMPCLIYLNISRNEIASLTLDSKIRSSSLKQLVLSFNSISFL
PDNLGRVLESLEELQLEGNNLTDLNIHLFLSELKLLDISKNNISVISDNVLSDCLRLEML
NASRNTLCSSPRLPLKLTTLNLSYNKFTCVPDVVLHLPYLRSVDMRNNDISLLPGPSQWE
SVNLRELIFSYNQISVLNLEEGVFKWSRLEKLHLCKNKLKEIPPQIGLLENLSSFDVSNN
SDLKCFPDEMGKLERLWDLPLDGLQLDLDLKHIGSKTKDIIRFLQQRLKKAVPYYRMKLM
LVGNTGSGKTTLLHRLMKLKRLRSRSERTTVGIDVKDWKIQDKGKTNIVLNVWDFSGREE
FYSSHPHFMTQRALYLVVYDVSKGVTEVDAIKPWLFNIKARAPSSPVILIGTHADVSDEK
HQEACTWKISSELLNNFGFPIIREHHLINAKDESDSIGKLRKAIVKEIMNFKIRDQPVMG
QLIPYSYLELEKRILQERKKVAAEFPVICHSRLLDIVVENQILLEENELSHAVHFLNESG
VLLHFEDPALQFRDLYFVDPQWLCNIISQILTIKGGSNSKFPKGIIQRSDVEKCILQHKN
FPKNYISQYFKLLERFQIALPLGEEQLLIPSSLSDQKPVIELPHCENSEIIVRLYEMPYF
PMGFWSRLINRLLEVSSFFFAGREKALRLNRMYWRQGIYLNWSPEAYCLVESDILDNETE
SFLRITVPSAQRGRILLGQIVDHIDSLLEEWFPGLLATDICREGGTLLKKWAVYSFGDDQ
RCQKILLDDLLDCADKDCLLVNPEDSRSTIPISQIAPDLILADLPENIMLISDQLEMDLT
AEYLLGDGGFGSVYHAVYKNEDVAVKIFNKHASEMYLHRLLRQELAVLSHLHHPSLISLL
AVGYQPRMLVMELAPKGSLDTLFNQKKSNLNKTLQHRIALHVADGLRYLHSSMIIYRDLK
PHNILLFNFKTNSEIIAKISDYGISQYCCSMGIKTSEGTPGFRAPEVARGNVIYNKQADV
YSFGLLLYDILTCGERILDGLRFPSEFDEIAVQGNLPDPVKHYNCSPWPQFESLINDCMK
ENPDERPTSAQIFNILNSAELLCLIKEVKVPTEALNENDVASCLICSGETAWIGSGNKHK
GRILRLDMETGKYDTKPAPDCLITCLTLVHLPDEESDWLVSGTESGRLLVFSAANSAAKH
ELQEMSSAITSLLFYSQPKHSKEMNFLLAGIADGSLAVFNDAAIKCTEGRPQKIFHIGNV
NTPVVCLSEFAYSQDKNTIWAGCGSKIVSLTSDFEIWKTVDTKPNYQLQHRSFSEANITT
MVIDKYIYLSKQGSHIVEIWDKKTEKMSGLINCSGIIKDESKRTPKLFLAADDQVSRVTS
LHLQQNVTLWIGTERGHIILIDLATRQHIKVISGFWTSVISITVSQMERYGPKNVVVILG
NHCHRLHEQERNFLLSAWNCALPLEVQNLKKHVETREQIAIKMKLGSIEQI
NT seq
7536 nt
NT seq
+upstream
nt +downstream
nt
atgaagaggatggcttgtaaggataatcgagaggaacagttaaaaaagctcatcgtaaga
cttaaaaacacacaggaagataaaccgatagaaactctcattcagatccttgaagacttg
ctttttctcacttttgccgaggaccgtgttgaagaacattttgcagacaaacaactccac
gatcctctatcaacagtgctgaagaccttcatcgataatgcgggagttcaacaggttgga
tggtctttactttgcagactgattgaaatttgtccatcaactcttgacaaattgagtgcc
tcaaagaatgtatccagtatacacatgcagattctcaggatattagctgtgcacagtggc
catgttaaactgatgatgattggcctaagagcgttatctcttcttctgtattcagatgct
attgttttactgactttagatgatgaggtggatgttttctatctgattgtgagtgcaatg
aacactttctgcttcaatgaagaagttcagttatatggatgtaagtctttgcagcttctt
ttagaaagagttgcagatgagcatttaattgaatttgttgaaacgggggatcatatggca
attctgaatactataaaacagttccaaaataatgaagacactgtgctgcaagcattgaaa
gccttacttcctctggctggtccaattagcaatgtagaagttctgatgtccggaaatgaa
agatgctacagcttgataatgagcgcaatggaatctttctcaaaaaatgaaaaagtacag
gaaattggttgctgtttgttccagaaatttacatcagaaagttttcacaacattcttgta
cttaatggagttcataaatttattatcaaagcggccatgatgtaccagactaatgcaaaa
ctgcaagcatcagctctcatgtgcctggcttctctcactgaaacaatagttttaaacaaa
gatttgaatgagtacaaagaggaggatgacttgtgctggattgatgtatgttgcagagca
ttggatttacacattggcagtaaagaggtccaggctgctacttgctgggcactgaataac
cttcttgtttatgaaagtaagcttcatgaaatgtttggagatgaagatggaaggtatcct
gtgcatctgcaggtgatggctgctatgcttttacattcatcttcaaaagaagtgtttcag
gctacagcaaacactctggcgaccatggcaggacaaaatgttaaaatcagatcagtactt
ttatccagtgggatacacattaacatttttgaactaatgaagaagcacattggctttcca
gaagtggcagagagtgcgtgtcggcttttgtacaatctgttccaagtgaatgtggcatgc
cttgatgtggctaccatggccatggctgagattctgaatgctatgaaagtccataagtgt
tctccttcagttcagcttgaagcccttcgtgctgccttgctctttgtcagttctgacaaa
agtggaaaaacaaagatgtcattgcagtgtgacatagaagaatctgatatgatcaatgtt
accttaaaagtgattaaaaaccaatgtgttttagaaggagcacatacccttgtccttgat
actcttaacaagtttattgggagcccagtcattcaggactgtgggttgcgtgttctttgt
tcattagttgattgttctggagcactggagctaatgtctcagcagggggcaatagacacc
attctacatactttgcagatgtacccagatgaaaaagaaatcaactggttaggtcttaat
ctcctctgttgtctttttccgaagaagaagctctccctgggaacgattgctatcttgtgt
tcagttttggttaagtcattacttcgattcagagaagtattagaggtgcagctatgggga
tttagagcagtactagctttgcttgaaacatcaccagcatctgctgagcagctagaaaga
gaatcatttgatttgtttatctttcaacaagtgaacttcagtcccttagaagaaagattt
aaccagatgcagaagttgtattgtatgtgtctttcaatattagcaactgatggagagatt
agacatcgcatgcttgaaaaggcttgtgcagaagataactttgttatggctgaatgttta
atacatctgggtgctgacgtcaataagaaaacaaagaatgaatcattaatttataaggtt
tgtgaaaaagagtgtagttcagaattagtagagttacttttaaacagtgggacacatgaa
caggacattcgaaaggctctattcatcagtgttaagaagcgcaataatctaattattagc
ttaatactgaggaaacttggccttgatcaagcaaacagtgcaatttgtttaggtggcttt
cgactgggacatctcgagtcatcctggctaaatcccttattttctgagcgcaagacactt
aatttcagacagcaaacaagcaaaggaatgtctttagttcgtgtaattatgaaatatcaa
aaacagagaaacttgtctaagtctgtgacaagcaatcttgatacctttggctccggatac
atgtcagatgaagctgatgacagtggctttgtgacagagggcagcagtgtatttatgaat
gaagatattgaaagtgatgagagtagtggaatattctatcgcctcaaaaaaatccagtct
gactctgtaactgaatcatcctccctgcggcatcggaggagtaggcggccttcttctgag
gtcgaaattgcagagtctgaaccgaatccattgtttcagatgaaatacttaaaggcctca
accagccaaagaagcaagtatacttcaccatctagatcgcctgaactgtcatcgttatta
ggaatagagaaggagtgtataaaattgcttgacctttctggaaatgacttggacaacgtg
aatgctttttgtgggaagacaaccttgaattgctatcttgaacaagtacaaagactggag
ctacaccataacaacttattagagtttccagaaaagatttgtgaagttatgaagcatttg
acacatcttgatcttcacagcaacagatttacaatatttccattttacatgatgaaaatg
ccatgccttatctatttgaatatttcaagaaatgaaattgcgtctttgaccctggattct
aagataagatcttcaagtttaaaacagctggttctgtcatttaacagtatttcatttttg
cctgacaatcttggcagagttttggaaagcctcgaagagctacaactggaagggaacaac
ttgacagacctaaacattcacctgttcttgtcagagctcaaactcctggatattagtaaa
aataatatttctgtgatttctgataatgtgctttccgattgcctcagactggaaatgctc
aacgcttccagaaacacactgtgttcttccccaaggttaccactaaaactaacaacttta
aatctgtcttacaacaagttcacatgtgttccagatgttgttcttcatcttccctacctg
agatcagtggatatgagaaacaacgatataagtttacttcctggaccttcacaatgggag
tcagtcaacttaagagaactgattttcagttataaccaaattagtgttctgaatcttgaa
gaaggtgtattcaaatggtcaagacttgaaaaactgcatctgtgtaaaaataaactgaag
gagattcctccgcaaattggacttttagaaaatttatcatcttttgatgtcagcaacaac
tctgatttaaaatgtttcccagatgaaatgggaaagctagaacgtctttgggacttacct
cttgatggtttacagcttgatttggacttgaagcacattggaagtaaaacaaaagatata
ataaggttccttcagcagcgtctgaagaaggctgtaccctactatcgcatgaagttaatg
ctagtgggaaacacaggaagtggaaaaacaaccctattacatcgattaatgaagctaaaa
cgcttgcgttctcgctcagaaaggactacagttgggattgatgtaaaggactggaaaatt
caagacaaaggaaaaacgaatattgttttaaatgtctgggatttttcaggtcgagaagag
ttttacagttctcatcctcacttcatgacacagcgtgctttgtatcttgttgtttatgat
gtgagtaaaggtgtaactgaagtggatgcaattaagccctggctgtttaacattaaggct
agagccccatcatctccagttatactaattggcactcacgcagatgtgagtgatgaaaag
catcaggaagcatgtacatggaaaatatcaagtgagctactgaataattttggttttccc
attatccgagagcatcatcttataaatgcgaaagatgagtccgactccatagggaagctt
cggaaggccatagttaaagagatcatgaactttaagattcgagaccaaccagtaatgggc
cagctgatcccatatagttatttggaacttgaaaaaagaattctgcaggaacggaagaaa
gtggctgccgagtttccagtcatttgccacagtcgcttactggacatagttgtggagaac
cagattttactagaggagaatgaactttctcatgctgttcacttcctgaatgagtctggt
gttctcctccactttgaagacccagcactgcagtttagggatctttattttgtggatccc
cagtggttatgtaacataatttcacagatactaaccattaaaggtggttcaaattctaag
ttccccaaaggaattattcagcgttcagatgtggaaaaatgtattcttcaacacaagaac
tttccaaaaaattacatatcacaatatttcaagctgcttgaaaggtttcagattgcattg
cctttgggagaagaacagcttcttattcccagcagcttgtctgaccagaagccagtaata
gagcttccccattgtgaaaattcagagatcatagtgaggctttatgagatgccctacttt
cctatgggattctggtccaggctaatcaaccgtctgcttgaagtttcttctttcttcttt
gcaggaagagaaaaagctcttcgcctcaataggatgtactggagacaaggcatataccta
aactggtcaccagaagcatattgcctagttgagtcagatatactggataatgaaactgag
agtttcctcagaatcacagtgccttcagcccaaagaggtcgaattttgctggggcagatt
gtggatcacattgattctcttctagaagaatggtttcctggacttctagctacagacata
tgtagggaaggagggacacttttgaagaaatgggctgtatatagttttggggatgaccag
agatgtcagaaaattcttcttgatgatctccttgactgtgctgataaagattgcctttta
gttaatccagaagattcaagatccacaattcccatatctcagatagctccagatttaatt
cttgcggatttacctgaaaacattatgctcatcagtgaccagctagaaatggacctaact
gcagaatacctccttggtgatggaggatttggatcagtgtaccatgctgtgtataaaaat
gaagatgttgcggtgaaaatatttaacaaacatgcatcagaaatgtatctacacagactg
ctaagacaggagttggcagttctaagtcatctgcaccatcctagccttatttctctttta
gcagttggttatcaaccacgtatgctcgtcatggaattggcacctaaaggctcccttgat
acacttttcaaccagaaaaaaagcaacttaaataaaacccttcaacacagaatagcactg
catgtagctgatggactaaggtatcttcattcatcaatgataatatacagagatctaaaa
cctcacaatatcctcctttttaactttaagaccaattctgagatcattgcaaaaatttct
gattatggtatttctcagtactgctgcagcatgggcattaagacatcagagggcacacca
ggcttccgtgcacctgaggttgctcgtggaaatgttatctacaacaagcaggcagatgtg
tattcctttgggcttcttttatatgatatcttaacatgtggtgaaaggattttggatggt
ttgagattccccagcgagtttgatgagatagcagtgcaaggaaacttaccagatcccgtg
aagcattataactgttctccgtggcctcaatttgaaagtctaattaatgattgtatgaaa
gaaaaccctgatgaaagacctacctctgctcagatatttaatattcttaactcagcagag
ctgctttgtcttataaaggaagtcaaagttcctactgaagcacttaatgaaaatgatgta
gcctcctgtctaatatgcagtggagaaacagcatggataggaagtggcaataaacataaa
ggaagaattttgcggttggacatggaaactggcaaatatgatacaaagcctgctcctgac
tgtctgattacatgcctcacacttgtccatcttcctgatgaggaatcagactggcttgtc
tctggtacagagtctgggaggctcctggtcttcagtgcagctaactctgcggctaaacat
gaattgcaagaaatgtcgagtgccatcacttctctgcttttttactctcaaccaaaacac
agcaaagagatgaattttcttttagctggcatagcagatggaagtctagctgtttttaat
gacgctgcaatcaagtgcactgaaggaagaccacaaaagattttccatataggaaacgtc
aacacacctgtggtgtgtctgagtgaatttgcttattctcaagataaaaataccatctgg
gctggctgtggatcaaagattgtttcacttactagtgattttgaaatctggaaaactgtt
gatacgaaaccaaattaccagcttcagcatagatcttttagtgaagcaaatataaccaca
atggtgattgataaatacatctacttaagcaaacaaggaagtcacattgtggaaatatgg
gacaagaaaacagaaaaaatgtctggacttatcaactgttctggtataataaaagatgag
tcaaaaagaacccccaaactttttctggcggctgatgaccaagtttccagagttacatca
ctacaccttcagcaaaacgttactctttggattgggacagaaagaggacatataatattg
atagatttagctactcgccagcatatcaaagtcatttctggcttttggacttcagtcatc
tccatcacagtttcacagatggagcgatatggcccgaaaaatgttgtggtcatactaggt
aatcattgtcatcgtctacatgaacaggaaagaaattttcttttgtctgcctggaactgt
gcccttccacttgaagtgcaaaacttgaagaagcatgttgaaacaagagagcaaattgca
attaaaatgaagctaggttccattgaacaaatttaa
DBGET
integrated database retrieval system
