| Entry |
|
|---|
| Symbol |
ABCC1
|
|---|
| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
|
|---|
| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
|
|---|
| Organism |
psiu Phocoena sinus (vaquita)
|
|---|
| Pathway |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:psiu00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
116739899 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
116739899 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
116739899 (ABCC1)
04981 Folate transport and metabolism
116739899 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
116739899 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
116739899 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:psiu02000]
116739899 (ABCC1)
Enzymes [BR:psiu01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
116739899 (ABCC1)
Transporters [BR:psiu02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
116739899 (ABCC1)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
15:62711936..62843329
|
|---|
| AA seq |
1530 aa
MALRGFCSVDGSDPFWEWNVTWNTSSPDFTKCFQNTVLVWVPCSYLWACFPFYFLYLSRH
DRGYIQMTHLNKAKTALGFLLWIVCWADLFYSFWERSLGKLLAPVFLVSPTLLGITMLLA
TFLIQIERRRGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDAQVDVFRDVTFYIYFS
LVLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGMMVQGYRQPLESTD
LWSLNKEDTSEQVVPVLVKNWKKECAKSRKQPVKVVYSSKDPAKPKGSSKVDVNEEAEAL
IIKSPQKDWNPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFTGPEILKLLISFVNDRKAPD
WQGYFYTALLFVSACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTV
GEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMIFMVPLN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLK
KSAYLAAVGTFTWVCTPFLVALCTFAVYVTIDKNNILDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRIFLSHEELEPDSIQRWPIKDAGATNSITVKNATFTWARSEPPT
LHGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNV
SLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLAR
AVYCDSDIYLFDDPLSAVDAHVGKHIFENVVGPKGMLKNKTRILVTHGISYLPQVDVIIV
MSGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQGEPDDGLAGVGRPGKEMKQVENGM
LVTDAVGKQLQRQLSSSSYGGDVSRHHTSTAELQKPRPVEEDTWKLMEADKAQTGQVKLS
VYWDYMKAIGLFISFLSIFLFLCNHVASLASNYWLSLWTDDPIVNGTQEHTKVRLSVYGA
LGISQGITVFGYSMVVSVGGIFASRRLHLDLLHNVLRSPMSFFERTPSGNLVNRFSKELD
TVDSMIPQVIKMFMGSLFNVIGACIIILLATPMVAVIIPPLGLIYFFVQRFYVASSRQLK
RLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAV
RLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAV
ERLKEYSETEKEAPWRVQEMAPPSNWPQVGRVEFRDYGLRYREDLDLVLKHINVTIDGGE
KVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDVNIAKIGLHDLRFKITIIPQDPVLFS
GSLRMNLDPFSQYSDEEVWTSLELAHLKGFVSALPHKLNHECAEGGENLSVGQRQLVCLA
RALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLD
KGEIRECGPPSGLLQQRSLFYSMAKDAGLV |
|---|
| NT seq |
4593 nt +upstreamnt +downstreamnt
atggcgctccgcggcttctgcagcgtcgatggctcagaccccttctgggagtggaatgtc
acgtggaacaccagcagccccgacttcaccaagtgctttcagaacaccgtcctcgtgtgg
gtgccttgctcttacctttgggcctgcttccccttctacttcctctatctctcccgccat
gaccggggctacattcagatgacacatctcaacaaagccaaaactgccttgggatttttg
ctatggattgtctgctgggcagacctcttctactctttctgggaaagaagtttgggcaag
ctcctggccccagtgtttctggtcagcccaaccctcttgggcatcaccatgctgcttgct
acctttttaattcagattgagagaaggaggggagttcagtcctcagggatcatgctcact
ttctggcttatagccctactgtgtgccctggccatcctgagatccaaaatcatgactgcc
ttaaaagaggatgcccaagtcgacgtctttcgcgatgtcactttctacatttacttctcc
ctcgtgctgatccagcttgtgttgtcctgcttctcagaccgctcacccctgttctccgaa
accatccacgatcccaatccttgcccagaatccagcgcctccttcctttccaggatcacc
ttctggtggatcacagggatgatggtccagggctaccgccaacccctggagagcactgac
ctctggtccctgaataaggaggatacgtcagaacaagttgtgcccgttttggtaaagaac
tggaagaaggaatgtgcaaagtccagaaaacagccggtgaaggtcgtgtactcctccaag
gatcccgccaagccgaaagggagttccaaggtggatgtgaacgaggaggccgaggctttg
atcatcaagtccccccagaaggattggaacccgtccctgttcaaggtgttatacaagaca
tttgggccctacttcctcatgagcttcttgttcaaggctgtgcacgacctgatgatgttt
accggcccagagatcttaaagttgctcatcagcttcgtgaacgacaggaaggccccagac
tggcagggctacttctacacggcgctgctgttcgtcagcgcctgcctgcagaccctcgtg
ctgcaccagtacttccacatctgcttcgtcagcggcatgcggatcaagaccgccgtcatc
ggggctgtgtaccggaaggccctggtgatcactaattcagccagaaaatcgtccaccgtc
ggggagatcgtcaacctcatgtctgtggatgcccagaggttcatggacctggccacgtac
attaacatgatctggtcagctcctctgcaagtcatccttgccctctacctcctgtggctg
aacctgggcccctccgttctggctggagtggctgtgatgatcttcatggttcccctcaat
gcagtgatggccatgaagaccaagacctaccaggtggcccacatgaagagcaaagacaat
cggattaagctgatgaatgaaattctgaatgggatcaaagtgctaaagctttacgcctgg
gagctggcattcaaagataaggtgctggccatcaggcaggaggagctgaaggtgctgaag
aaatctgcctacctggccgccgtggggaccttcacctgggtctgcacacctttcctggtg
gccttgtgcacgtttgccgtctacgtgaccatcgacaagaacaacatcctggatgcccag
aaggccttcgtgtccttggccttgttcaacatccttcgcttccccctgaatattctcccc
atggtcatcagcagcatcgtgcaggcgagtgtctccctcaagcgcctcaggatcttcctc
tcccacgaggagctggaacccgacagcatccagcgatggcccatcaaagacgctggggcc
acaaacagcatcactgtgaagaatgccacgttcacttgggccaggagcgagcctcccacg
ctgcatggcatcactttctccattccggaaggttccctggtggccgtggtgggccaggtg
ggctgtgggaagtcgtctctgctctcagcgctcttggctgagatggacaaggtggaggga
cacgtggctatcaagggttcagtggcctacgtcccccagcaggcctggattcagaatgtt
tctctccgagaaaacatcctttttggacgccagctacaggaacggtattataaggctgtg
atagaagcctgtgccctcctcccagacctggaaatcctgcccagtggggaccggacagag
attggtgagaagggcgtgaacctgtctggcggccagaagcaacgcgtgagcctggcccgg
gccgtgtattgcgactccgacatctacctctttgacgatcccctctcggcggtggacgcc
cacgtggggaagcacatatttgaaaacgtggttggccccaaggggatgctgaagaacaag
acgcggatcctggtcacgcacggcatcagctacctgccccaggtggatgtcatcatcgtc
atgagtggtggcaagatctccgagatgggctcctaccaggagctgctggcccgggacggg
gcctttgccgagttcctgcgcacgtacgccagcgccgagcaggagcaaggggagcccgac
gacggcttagcaggtgttggcaggccagggaaggagatgaagcaggtggagaacggcatg
ctggtgacggacgctgtggggaagcaactgcagagacagctcagcagctcctcctatggc
ggggatgtcagccggcaccacaccagcaccgcggagctgcagaagcccaggcccgtggag
gaggacacctggaagctgatggaggcagacaaggctcagactgggcaggtcaagctctcc
gtgtactgggactacatgaaggcgataggacttttcatctcctttctgagcatcttcctt
ttcctgtgtaaccacgttgcttctctggcctctaactattggctcagtctctggactgat
gaccccatcgtcaatgggacccaggagcacacgaaagtccggctgagcgtctatggagcc
ctgggcatttctcaaggtatcacagtgttcggctactccatggtggtgtccgtcgggggc
atcttcgcctcgcgccgcctgcacctggacctgctgcataacgtcctcaggtcgcccatg
agcttcttcgagcggacccccagcgggaacctggtgaaccgcttctccaaggagctggac
acagtggactcgatgatccctcaggtcatcaagatgttcatgggctccctgttcaacgtc
attggcgcctgcatcatcatcctgctggccactcccatggtggccgtcatcatcccgccc
ctgggcctcatctacttctttgtccagaggttctacgtggcctcctcccggcagctgaag
cgcctcgagtcagtcagccgctccccggtttattcccacttcaacgagaccctgctgggg
gtcagcgtcatccgcgccttcgaggaacaggagcgcttcatccgccagagcgacctgaag
gtggacgagaaccagaaggcctattaccccagcatcgtggccaacaggtggctggctgtg
cggctggagtgtgtaggcaactgcattgtcctgtttgccgccctgtttgcagtgatctcc
cggcacagtctcagtgctggcttggtgggcctctcggtgtcttactcactgcaggtcacc
acatacttgaactggcttgttcggatgtcgtccgagatggagaccaacattgtggccgtg
gagagactcaaggagtattcagagactgagaaggaggctccctggcgagtccaggagatg
gcaccccccagcaactggccccaggtgggccgagtggagttccgagactacggcctgcgt
taccgagaggacctggacctggttctcaagcacatcaacgtcaccatcgatggaggggag
aaggttggcatcgtggggcggacaggagctgggaagtcatccctgaccctgggcttgttt
cgtatcaacgagtctgccgagggagagatcatcattgacgatgtcaacattgccaagatc
ggcctgcacgacctccgcttcaagatcaccatcatcccccaggaccccgttttgttttcg
ggttccctccgcatgaacctggacccattcagccagtattcagatgaagaggtctggacg
tctctggagctggcccacctgaagggcttcgtgtcggcccttccccataagctgaaccac
gagtgcgcagaaggcggggagaacctcagcgtcgggcagcgccagcttgtctgcctggcc
cgggccctgctgaggaagacgaagatccttgtgttggatgaggccacggcggctgtggac
ctggaaacggatgacctcattcagtccaccatccggacacagtttgacgactgtaccgtc
ctcaccattgctcaccggctcaacaccatcatggactacacgagggtgattgtcctggac
aaaggggagatccgggagtgtggtcccccctccggcctcctgcaacagagaagtctcttc
tacagcatggccaaagatgctggcttggtgtga |
|---|
