KEGG   Phocoena sinus (vaquita): 116740988
Entry
116740988         CDS       T07759                                 
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
psiu  Phocoena sinus (vaquita)
Pathway
psiu01522  Endocrine resistance
psiu04015  Rap1 signaling pathway
psiu04020  Calcium signaling pathway
psiu04024  cAMP signaling pathway
psiu04072  Phospholipase D signaling pathway
psiu04081  Hormone signaling
psiu04082  Neuroactive ligand signaling
psiu04261  Adrenergic signaling in cardiomyocytes
psiu04270  Vascular smooth muscle contraction
psiu04540  Gap junction
psiu04611  Platelet activation
psiu04713  Circadian entrainment
psiu04714  Thermogenesis
psiu04724  Glutamatergic synapse
psiu04726  Serotonergic synapse
psiu04728  Dopaminergic synapse
psiu04730  Long-term depression
psiu04750  Inflammatory mediator regulation of TRP channels
psiu04911  Insulin secretion
psiu04912  GnRH signaling pathway
psiu04913  Ovarian steroidogenesis
psiu04915  Estrogen signaling pathway
psiu04916  Melanogenesis
psiu04918  Thyroid hormone synthesis
psiu04921  Oxytocin signaling pathway
psiu04922  Glucagon signaling pathway
psiu04923  Regulation of lipolysis in adipocytes
psiu04924  Renin secretion
psiu04925  Aldosterone synthesis and secretion
psiu04926  Relaxin signaling pathway
psiu04927  Cortisol synthesis and secretion
psiu04928  Parathyroid hormone synthesis, secretion and action
psiu04934  Cushing syndrome
psiu04935  Growth hormone synthesis, secretion and action
psiu04961  Endocrine and other factor-regulated calcium reabsorption
psiu04962  Vasopressin-regulated water reabsorption
psiu04970  Salivary secretion
psiu04971  Gastric acid secretion
psiu04972  Pancreatic secretion
psiu04976  Bile secretion
psiu05012  Parkinson disease
psiu05030  Cocaine addiction
psiu05031  Amphetamine addiction
psiu05032  Morphine addiction
psiu05034  Alcoholism
psiu05142  Chagas disease
psiu05146  Amoebiasis
psiu05163  Human cytomegalovirus infection
psiu05165  Human papillomavirus infection
psiu05200  Pathways in cancer
psiu05207  Chemical carcinogenesis - receptor activation
psiu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:psiu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    116740988 (GNAS)
   04020 Calcium signaling pathway
    116740988 (GNAS)
   04072 Phospholipase D signaling pathway
    116740988 (GNAS)
   04024 cAMP signaling pathway
    116740988 (GNAS)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    116740988 (GNAS)
   04081 Hormone signaling
    116740988 (GNAS)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    116740988 (GNAS)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    116740988 (GNAS)
  09152 Endocrine system
   04911 Insulin secretion
    116740988 (GNAS)
   04922 Glucagon signaling pathway
    116740988 (GNAS)
   04923 Regulation of lipolysis in adipocytes
    116740988 (GNAS)
   04912 GnRH signaling pathway
    116740988 (GNAS)
   04913 Ovarian steroidogenesis
    116740988 (GNAS)
   04915 Estrogen signaling pathway
    116740988 (GNAS)
   04921 Oxytocin signaling pathway
    116740988 (GNAS)
   04926 Relaxin signaling pathway
    116740988 (GNAS)
   04935 Growth hormone synthesis, secretion and action
    116740988 (GNAS)
   04918 Thyroid hormone synthesis
    116740988 (GNAS)
   04928 Parathyroid hormone synthesis, secretion and action
    116740988 (GNAS)
   04916 Melanogenesis
    116740988 (GNAS)
   04924 Renin secretion
    116740988 (GNAS)
   04925 Aldosterone synthesis and secretion
    116740988 (GNAS)
   04927 Cortisol synthesis and secretion
    116740988 (GNAS)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    116740988 (GNAS)
   04270 Vascular smooth muscle contraction
    116740988 (GNAS)
  09154 Digestive system
   04970 Salivary secretion
    116740988 (GNAS)
   04971 Gastric acid secretion
    116740988 (GNAS)
   04972 Pancreatic secretion
    116740988 (GNAS)
   04976 Bile secretion
    116740988 (GNAS)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    116740988 (GNAS)
   04961 Endocrine and other factor-regulated calcium reabsorption
    116740988 (GNAS)
  09156 Nervous system
   04724 Glutamatergic synapse
    116740988 (GNAS)
   04728 Dopaminergic synapse
    116740988 (GNAS)
   04726 Serotonergic synapse
    116740988 (GNAS)
   04730 Long-term depression
    116740988 (GNAS)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    116740988 (GNAS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    116740988 (GNAS)
   04714 Thermogenesis
    116740988 (GNAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116740988 (GNAS)
   05207 Chemical carcinogenesis - receptor activation
    116740988 (GNAS)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    116740988 (GNAS)
   05165 Human papillomavirus infection
    116740988 (GNAS)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    116740988 (GNAS)
   05142 Chagas disease
    116740988 (GNAS)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    116740988 (GNAS)
  09165 Substance dependence
   05030 Cocaine addiction
    116740988 (GNAS)
   05031 Amphetamine addiction
    116740988 (GNAS)
   05032 Morphine addiction
    116740988 (GNAS)
   05034 Alcoholism
    116740988 (GNAS)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    116740988 (GNAS)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    116740988 (GNAS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    116740988 (GNAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:psiu04147]
    116740988 (GNAS)
   04031 GTP-binding proteins [BR:psiu04031]
    116740988 (GNAS)
Exosome [BR:psiu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   116740988 (GNAS)
  Exosomal proteins of other body fluids (saliva and urine)
   116740988 (GNAS)
  Exosomal proteins of colorectal cancer cells
   116740988 (GNAS)
  Exosomal proteins of bladder cancer cells
   116740988 (GNAS)
GTP-binding proteins [BR:psiu04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    116740988 (GNAS)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA GTP_EFTU
Other DBs
NCBI-GeneID: 116740988
NCBI-ProteinID: XP_032463068
Ensembl: ENSPSNG00000016734
LinkDB
Position
15:complement(4299771..4366577)
AA seq 1032 aa
MGMRNCLDGNNMSGQRNIPLELGEQPEQPPLEAPGAAAPGAGPGAAEEMETPPPHSEPIP
VEIEGEACGPPEVSRPKFQDLSQAIKEAGAHGDYSPPPEEAMPFEVEQSSLGAFWPTLEH
PGDTTGAHAGLEAFSPPIVEPRAFGEARPSLGSYSPPPEEAMPFEFEQPAQGGCNQPLLQ
VSDLAPGGPGAGVSRAPPEEPRALRPEKAGFGGGCSPPREEDVPFEFDGAAFGDDSPPPG
LPQAIPQIDGLGGNQIAAVAAPSAVLLAPAANEPPLWVPSIIGSPSREAVRPPPHFAGNS
PPMEISGPPREIGSAPVGVDDAPVNVDSPPIALDGPPIEVSRAPVKREQAEGERPPVEGE
AAEMEGGSADAAAERGKVPDPGDGAPAAGAAPDAPAAGAAPDAPAAGAAPDAPAAGAAPD
APAAGAAPAGPDTPAAGAAPAARAAPVARAAPVARAAPVARATPVPRAAPAAWATPASGA
RPKISFLRPPSPEIQAADPPTPQPPRAYAWRGRSERSCYRGHDDEISVSSDSGDESDDGT
FGCHRWFQSRRNRRHRKTQRNLLRNFLVQAFGGCFCRSESPQSRGSLSPKVKKVALAEKR
RQTHKESVEKRAQKCAEKKRSKLIDKQLKNEKMGYMCTHRLLLLGRKVVPYNTEGRFQLD
KPAPATVRRRRVVGWGTARKAGASGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARS
NSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDF
PPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRV
LTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQ
TNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPE
DATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDI
IQRMHLRQYELL
NT seq 3099 nt   +upstreamnt  +downstreamnt
atgggcatgcgcaactgcctcgacggcaataatatgtcaggacaacgcaatatccccctt
gaactcggcgaacagcccgagcaaccacctttggaggccccaggggcagctgcccccggt
gctgggcctggcgcagccgaagagatggagaccccaccgcctcacagcgagcccatcccc
gtcgagattgaaggcgaggcctgtggacccccagaagtctccagacccaagttccaggac
ctcagccaggccatcaaggaagccggagcccatggagactacagcccacctcctgaagaa
gccatgcccttcgaggtcgagcagtccagcttgggagccttctggcctaccctggagcac
cctggagacaccactggggcccatgcaggccttgaagccttcagcccaccgatcgtggag
cccagagccttcggtgaggccaggccaagcctgggaagctacagccctcctcccgaagaa
gctatgccctttgagtttgagcagcctgcccagggaggctgcaaccaacctctcttgcag
gtctcagacctcgctccaggaggtccgggtgcgggggtctctagggctcctcccgaggag
ccccgggctctcagacctgagaaagcaggcttcggaggaggatgcagccctccccgtgag
gaggatgtgccatttgagtttgatggagcagcctttggggacgacagcccaccccctggg
ctcccccaagctatcccacaaatcgacggccttggcggcaaccagatcgcggcagtcgcg
gccccgagtgcggtcctcctcgctcccgccgcgaacgagccccccctctgggtcccaagc
atcatcggcagcccatctcgagaggctgtcagacctcctccacacttcgcgggcaacagc
cccccgatggagatctccggacccccgcgcgagattggcagcgcccccgttggggtcgac
gacgctcccgtcaacgtggacagccccccaatcgcgcttgacggcccgcccatcgaggtc
tcccgagccccagttaagagagagcaagcagagggagagagacccccagttgagggagaa
gcagccgagatggaaggaggctcagccgacgctgccgcggagagaggcaaagtccccgat
cccggagacggagcccctgccgccggagcagcccctgacgcgccagccgccggggcagcc
cctgacgcgccagccgccggggcagcccctgacgcgccagccgccggggcagcccctgat
gctcctgccgccggggcagcccctgccggccctgacacgccagccgccggggcagcccct
gccgcccgggcagctcctgtcgcccgggccgcccctgtcgcccgggccgcccctgtcgcc
cgggccacccctgtcccccgggccgctcccgccgcctgggcaaccccagcctctggagcc
cgacccaagatcagtttccttagaccccccagccccgagatccaggctgccgatccgcct
actccgcagcctcctcgcgcatatgcctggcggggcaggtctgagcgcagctgctaccgc
ggccacgacgacgaaatatcggtcagcagcgacagcggagacgaatccgacgatgggacc
ttcggatgccaccgctggtttcagtccaggcgaaaccgccgccaccgaaagacccagcgc
aacttgctccgcaacttcctcgttcaggccttcggaggctgcttctgcagatccgagagc
ccccagtccagaggctccctcagccccaaggtcaagaaggttgccctggcggagaagcgc
agacagacccacaaggaaagcgtggagaagcgcgcccagaagtgcgcagagaagaaacgc
agcaaactcatcgacaagcagctcaagaacgagaagatgggctacatgtgtacgcaccgc
ctgctgcttctagggagaaaagtggtgccgtacaacactgagggtcgtttccagctggac
aaaccagcgccagcgaccgtaagacgtcgccgagtcgtggggtgggggacggcaagaaag
gcgggggcttcaggtgctggagaatctggtaaaagcaccatcgtgaagcagatgaggatc
ctgcatgttaatgggtttaatggagagggcggcgaagaggacccgcaggccgcaaggagc
aacagcgatggtgagaaggcaaccaaagtgcaggacatcaaaaacaacctgaaagaggcc
attgaaaccatcgtggccgccatgagcaacctggtgccccccgtggagctggccaacccc
gagaaccagttcagagtggactacattctgagcgtgatgaacgtgccagactttgacttc
cctcccgaattctacgagcacgccaaggctctgtgggaggacgagggggtgcgtgcctgc
tacgagcgctccaacgagtaccagctcatcgactgtgcccagtacttcctggacaagatt
gacgtcatcaagcaggctgactatgtgcccagcgaccaggacctgctgcgctgccgtgtc
ctgacctctggaatctttgagaccaagttccaggtggataaagtcaacttccacatgttc
gatgtgggcggccagcgtgatgaacgccgcaaatggatccagtgcttcaatgatgtgact
gccatcatcttcgtggttgccagcagcagctacaacatggtcatccgggaggacaaccag
accaaccgcctgcaggaggcgctgaacctcttcaagagcatctggaacaacagatggctg
cgcaccatctctgtgattctgttcctcaacaagcaagatctgctcgctgagaaagtcctt
gctggaaaatcgaagattgaggactactttccagaatttgctcgctacactactcctgag
gatgcgactcctgagcccggagaggacccacgcgtgacccgggccaagtactttattcga
gatgaatttctgagaatcagcactgctagtggagacgggcgccactattgctaccctcac
ttcacctgcgctgtggacacagagaacattcgccgtgtgttcaacgactgccgtgacatc
atccagcgcatgcacctccgtcagtatgagctgctctaa

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