Phocoena sinus (vaquita): 116741248
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Entry
116741248 CDS
T07759
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu00562
Inositol phosphate metabolism
psiu01100
Metabolic pathways
psiu04014
Ras signaling pathway
psiu04015
Rap1 signaling pathway
psiu04020
Calcium signaling pathway
psiu04024
cAMP signaling pathway
psiu04070
Phosphatidylinositol signaling system
psiu04919
Thyroid hormone signaling pathway
psiu04933
AGE-RAGE signaling pathway in diabetic complications
psiu05205
Proteoglycans in cancer
Module
psiu_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
116741248 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
116741248 (PLCE1)
04015 Rap1 signaling pathway
116741248 (PLCE1)
04020 Calcium signaling pathway
116741248 (PLCE1)
04070 Phosphatidylinositol signaling system
116741248 (PLCE1)
04024 cAMP signaling pathway
116741248 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
116741248 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
116741248 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
116741248 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
psiu04131
]
116741248 (PLCE1)
Enzymes [BR:
psiu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
116741248 (PLCE1)
Membrane trafficking [BR:
psiu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
116741248 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
116741248 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
EGF_Pikachurin
Motif
Other DBs
NCBI-GeneID:
116741248
NCBI-ProteinID:
XP_032463330
Ensembl:
ENSPSNG00000013785
LinkDB
All DBs
Position
16:52145530..52458287
Genome browser
AA seq
2303 aa
AA seq
DB search
MTSEEMAASVLRPVTQRKVISAQSAVDESNDKVSDISVPKTHPVRQSGETSHTISQLTKL
TEESSGSNLPQILSVAREKITSDENSNEECWEKSIPDSVKNLNINCNNILKIHQCGLPQS
QFYETCDSTTEEGLCLETGIPSSLERKVFPGIQLEIDRPPAGIISPLGTQSTIIETGRAH
PDSNMAVFHFQYEVDRRMSDTFCPLSDNLILDDCGNCVLPAVGGEQKNNYMAYTCNLMEL
ASNCDSKNRQLQYDHCDPLNDKYLCFEGSCPKADVVCSSDSFCGEDFTDSPPAKTFLSHF
EDFPDNCEDAEEDLFKSKKERSTWLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLGA
WSYVDRKRNGLLLPCGRVMERLSTVVTRQDGGQCPSEAQWYPIYSAVRRGEETEETIRSL
LHFFTKLPASETAHERISIGPCLKQCVQDTVCEYRATLQRTSISQYITGSLLEATTSLGA
RSSLLSSFGGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASIL
MEQEQNIYRRVLPVDYLCFLTRDLGTTECQRSLPCLKASISASILTSQNGEHNALEDLVM
RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKM
WQFMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDG
ASGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSR
SLETEEEDSPSEGSSARKNSLKDKARWQFIIGDLLDSENDIFEEPQECDPHGTEEPQKAF
DHGTELIPWYVLSIQADVHQFLLQGATVIHYDQDMHLSARCFLQLQPDNSTLTWIKPTTA
SPASAKAKLGVLSNTSEPGKFPLLGNAGLSGLAEGVLDMFSAKAVYMGHPSIDIHTVCVQ
NKLSNMSLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQR
QQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNMQRNNTL
GISTTKKKKKILMRGESGEATDDEMATRKAKTHKECRSRSGSDPQDVNEQEESEANAITS
PPNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGG
MKGFQSFMVSDSSMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCDRAGSTAAPLYTNLT
IDENTSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSL
GVFGVGILQLNDFLVNCQGEHYTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDN
FASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELD
CWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAE
IFKTVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQL
ASMQAQAYNGGSANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEY
NEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPG
LSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASPNKTSGKSSCEGIRQAWEDSPSSV
NPATSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNP
SPLLFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPL
ERDLDNMEPAIYSLTIVSGQNVCPSNGTGSPCIEVDVLGMALDSCHFRTKPIHRNTLNPM
WNEQFLFRVHFEDLLFLRFAVVENNSSVVTAQRIIPLKALKRGYRHLQLRNLHNELLEIS
SLFINSRRMEENSSGNTMPASLMFNTEERKCLRIHRVTVHGVPGPEPFAVFSINGGTKAK
QLLQQSLTIDQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFP
EEGYVGRIVLKTQQENLEEKSIVQDDKEMILSSEEESFFVQVHDVSPEQPRTVIKAPRVS
TAQDVIQQTLCKAKYSYSILSNPNPGDYVLLEEVVKDTANRKSSTPKSSQRVLLDQECVF
QAQSRWKGAGKFILKLKEQVQASREDKRKGISFASELKKLTKSTKQPRGLTSPSQVLASE
NVQNKEEKSVGGLSSSDTIDYRQ
NT seq
6912 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgttctcagacctgtgactcagcgaaaagtgata
tctgctcagtcggctgtagatgaaagtaatgataaggtctcggacatcagtgttccaaag
acgcatcctgtcaggcagagcggggagacttctcataccatctcacaactgaccaaactt
acagaagaatcttctggaagcaacttgccccagattctctcagtagcaagggagaaaata
acgagtgatgagaacagtaatgaagagtgctgggagaaaagcataccagactctgtgaaa
aaccttaacattaactgcaacaacatactgaaaatccatcagtgtggccttcctcagagc
cagttttatgaaacgtgtgattctaccacagaggaaggcctgtgtttggaaactggaatc
ccttcttcactggaaagaaaggtgttccctggaattcaactggaaatagacagacctccc
gcaggcattattagtccattaggaactcaatcaaccatcatagagacgggcagggcacac
cctgacagcaacatggcggtatttcactttcagtatgaagttgacagaagaatgtcagac
actttctgtcctctgtcagataacttgattttggatgattgtggaaactgtgtactacct
gctgttggtggggaacaaaagaacaattacatggcgtatacttgtaacctgatggaattg
gcaagtaactgtgacagtaagaataggcagctgcagtatgatcattgtgaccccttgaat
gacaaatacttgtgctttgaaggctcttgcccgaaggccgatgtagtatgttcaagtgac
agcttttgtggggaggattttacggacagtccacctgccaagacctttctgagccatttt
gaggacttccctgataattgtgaagatgcagaagaagatttattcaaaagcaagaaggag
cggtccacttggctagtgaggagattttgtaaaaatgacagggaagtaaagaaatctgtg
tacactgggacaagggcaattgtgagaactctgccttccggtcacattgggctgggggct
tggagttacgttgatcggaagagaaacggtctcttactgccttgtgggagagtcatggaa
cggctgtcaacagtggtgacgaggcaagatgggggccaatgtccgtcagaagcccagtgg
tatccgatctacagtgcagtgagaaggggagaagaaacagaagagacaattagatctctt
ctccatttcttcacaaagctcccagcctccgagacagcccatgaaaggattagcattggt
ccgtgcttaaagcaatgtgtccaagacactgtttgtgagtatcgtgccaccctccaaagg
acttccatatctcagtacatcaccggctctctgctagaagccaccacatctttaggagca
agaagtagccttctcagttcttttggaggatccaccggacgaatgatgctgaaagaacgc
caaccaggcacctctatggccaattccagtgccctcccttcaagttcagctgggatcagc
aaggagctgattgatctgcagcccctcatccagttcccagaggaagttgccagcatccta
atggagcaggaacagaatatttaccgaagggtcttgccggttgactatctttgcttcttg
acccgggacttgggcactacggaatgccagaggtccctgccctgcctcaaagcgtccatc
tcagcatccattcttacctcccagaacggagagcataatgcccttgaagatcttgtgatg
agatttaatgaggtgagctcctgggtgacgtggctgatcctcacggcgggctccatggag
gagaagcgggaagtcttctcatatttggtgcatgtggccaaatgctgctggaacatgggc
aactacaacaccgtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatg
tggcagtttatggaccagtctgacctggagacgatgagaagcctgaaggacgccatggcc
cagcatgaatcttcctgcgagtacaggaaggtggtgactcgggcgctgcacatccctggc
tgtaaggtggttccattctgcggggtgtttctgaaggagctctgtgaggtgcttgatgga
gcctccggcctcatgaagctttgcccgaggtacaattcccaagaagaaactctagagttt
gtagccgattatagtggacaagataatttcttacaacgagtgggacagaatggcttaaag
aattcagagaaggagtccaccgtcaacagcatctttcagatcatcagaagctgcagtcga
agtctggagacagaagaggaggacagccccagtgaggggagcagcgctaggaaaaattcc
ctgaaggataaagcccgatggcagtttataattggagatttgttggattctgaaaatgac
atctttgaggagccccaagaatgcgaccctcatggaacagaagagccacagaaggccttt
gaccatgggacagagctcatcccgtggtacgtgctgtccatccaagctgatgtgcaccag
ttcctgctgcagggggccacggtcatccactatgaccaggacatgcacctctctgcccgc
tgcttcctccagcttcagcctgacaatagcaccttgacctggataaagcccaccactgct
tccccagccagtgctaaagcaaaacttggtgtgcttagtaacacatccgagcctggcaaa
ttcccattgctgggcaatgctggattaagtggcctggcagagggggtcttggatatgttt
tcagcaaaggctgtgtacatgggacaccctagcattgatatacacactgtgtgtgtccag
aacaaactgagtaacatgtctctctcagagactggtgtgacactgctctacgggcttcag
accacggacaataggttattgcactttgtggcaccaaagcacacagctaaaatgctcttc
agtggattgttggaactcacgagagctgtgagaaagatgaggaagttccctgaccaaaga
cagcagtggctgcggaaacaatacgtcagcctctaccaggaggatggacgatatgaaggc
ccaactttggctcacgctgtggagttgtttggcggcagacgatggagtactcgaaacccc
agtcccgggacatcagcaaagagtgctgagaagcccaacatgcagagaaacaacaccttg
ggtataagcaccaccaagaaaaagaagaaaatccttatgaggggtgagagtggagaggcc
accgatgatgagatggccacccgcaaagccaaaacgcacaaagagtgtcggagccggagt
ggttctgaccctcaagacgttaatgaacaagaagaatcagaggcgaacgccatcacgagc
cctcctaaccctctcccttccagaagagcccactctttgaccacggctgggtcccctaac
ttggctgccgggacgtcatctcccatcaggccagtgtcctcccctgtgctgtcttcttca
aacaagagcccgtccagtgcttggagcagcagcagctggcatgggcggatcaaaggagga
atgaagggctttcagagcttcatggtttcagacagcagcatgagttttgtggagtttgtt
gagctgttcaaatcattcagtgtgaggagccgcaaggacctgaaggatctctttgacatc
tatgccgtaccctgcgaccgagccggctccacagcggcccccctctacaccaacctgacc
attgacgaaaacaccagtggtcttcagcctgacctagatttgttgaccagaaatgtctcc
gatttggggttattcattaagagtaaacagcagctgtctgacaaccagaggcagatatct
gatgccattgctgctgcaagtatcgtgacaaatggcactggggtggagagcacatccctg
ggcgtatttggagttggcatcctccagctcaatgacttcctagtgaattgccaaggagaa
cactacacttatgatgaaatcctcagcatcatccagaagttcgagcctagtgttagtatg
tgtcatcagggcctaatgtcgtttgaaggatttgcaaggtttctgatggataaagataat
tttgcctcgaaaaatgatgaatcgcaggagaacattaaagaattgcaactgcccctctcc
tattattacattgaatcttcacacaatacctacctcacaggccatcaactcaaaggagaa
tcctcagtagaactctacagccaggtcctcctgcaaggctgtaggagtgtagagttggac
tgctgggacggagatgatgggatgcccatcatttatcatggacacaccctgacaaccaag
atccccttcaaggaagtggttgaagccatcgatcgcagtgcctttatcaactctgacctc
cccatcatcatatccattgagaaccactgttcattgcctcagcaacgaaaaatggcagaa
attttcaagactgtgtttggagaaaagctggtggctaaattcttatttgagagtgatttc
tcagatgatccaatgcttccctcacctgaccaactcaggaggaaagtacttctcaaaaat
aagaagttaaaagcccatcagacaccggtggatatattaaagcaaaaggctcatcagcta
gcatccatgcaagctcaggcttataatggtggcagtgccaaccctccacctgctaataac
gaagaagaggaagatgaagaggacgaatatgattatgactatgaatccctctctgacgac
aacattctagaagacagacctgaaaataaatcatgtaatgacaaacttcagtttgagtat
aatgaagaaatccccaagaggataaagaaagcagataactctgcttgcaacaaaggaaag
gtttatgacatggaactgggagaagaattttatcttcctcagaataaaaaggaaagcaga
cagattgcaccagagctttctgaccttgtcatctattgccaagcagtaaagtttccaggc
ctgtcaactctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtcc
atttttggcaacaatccgggcagaatgagccccggggagacagcatcacctaacaaaaca
tctggaaaaagttcctgtgaaggaatccgacaggcctgggaggactcgccttcctctgtc
aacccagccacgtccctcagcgctatcattagaactcccaaatgctaccacatctcctcg
ctgaatgaaaatgctgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcac
actgcctgccagctgctgaggacgtatccggccgccacccgcatcgactcatccaacccc
agccccctcctcttctggctccatgggatacagctcgtggcgctcaactaccagacagat
gatctccctttacatttaaatgctgccatgtttgaggccaacggtggctgtggttatgtt
ctgaaacccccagttctgtgggacaagaactgtcccatgtatcagaagttttctcccttg
gaaagagacctggacaacatggagcctgccatctattctttaactatcgtctctgggcag
aacgtgtgcccgagtaacggcacgggaagcccgtgtatagaggtcgacgtcctgggcatg
gccctggatagctgccacttccgcacgaagcccatccaccgcaatactctgaaccccatg
tggaatgaacagttcctcttccgggttcactttgaagatctcctatttcttcgttttgcc
gttgtggagaacaacagctcggtggtaactgcgcagagaatcatccccctcaaggctcta
aagcgaggatatcgacatcttcagctgcggaacctccacaatgaactcttggaaatctct
agtttattcataaacagcaggaggatggaagaaaattcctctggcaatactatgccggcc
tctttgatgtttaatacagaagaaagaaaatgtctgcggattcacagagtcacagtacat
ggggtcccaggtccagagccctttgctgttttctccataaatggaggcaccaaggcaaag
cagcttctccaacaaagtctgaccattgatcaagacaccaaacctattgccacagactat
tttttaatggaagaaaaatattttatatctaaagaaaagaatgaatgtaggaaacaaccg
ttccagagggccattggtccagaagaagagatcatgcagattttaagcagctggtttccc
gaagagggatacgttggcaggattgtcttaaaaacccagcaggaaaacctggaagagaag
agcatcgttcaagatgacaaggagatgatcctgagctcagaggaggagagtttctttgtc
caagtgcatgacgtttctcctgagcaaccgcgaacagtcatcaaggcgccccgcgtcagc
actgcacaggacgtcattcagcagaccttatgcaaagccaaatattcctatagcatcttg
agcaacccgaacccaggtgattacgtgcttttggaagaggtggtgaaagacactgccaac
aggaagtcttctaccccgaagtcctcccagcgtgtccttttggatcaggagtgtgttttt
caagctcaaagcaggtggaaaggtgcaggaaaattcatccttaagctaaaggaacaagtg
caggcatcccgagaagacaaaagaaaaggcatctcttttgcaagcgaactcaagaagctc
accaagtcgactaaacagccccgaggactcacatcaccttctcaggtcctggcctccgaa
aatgtccaaaacaaggaggagaaatctgtgggcggcttgtcctccagtgacacgatagac
tatcgacagtga
DBGET
integrated database retrieval system
