KEGG   Phocoena sinus (vaquita): 116741257
Entry
116741257         CDS       T07759                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
psiu  Phocoena sinus (vaquita)
Pathway
psiu01522  Endocrine resistance
psiu04010  MAPK signaling pathway
psiu04012  ErbB signaling pathway
psiu04014  Ras signaling pathway
psiu04024  cAMP signaling pathway
psiu04068  FoxO signaling pathway
psiu04071  Sphingolipid signaling pathway
psiu04137  Mitophagy - animal
psiu04140  Autophagy - animal
psiu04141  Protein processing in endoplasmic reticulum
psiu04210  Apoptosis
psiu04215  Apoptosis - multiple species
psiu04217  Necroptosis
psiu04310  Wnt signaling pathway
psiu04380  Osteoclast differentiation
psiu04510  Focal adhesion
psiu04530  Tight junction
psiu04620  Toll-like receptor signaling pathway
psiu04621  NOD-like receptor signaling pathway
psiu04622  RIG-I-like receptor signaling pathway
psiu04625  C-type lectin receptor signaling pathway
psiu04657  IL-17 signaling pathway
psiu04658  Th1 and Th2 cell differentiation
psiu04659  Th17 cell differentiation
psiu04660  T cell receptor signaling pathway
psiu04664  Fc epsilon RI signaling pathway
psiu04668  TNF signaling pathway
psiu04722  Neurotrophin signaling pathway
psiu04723  Retrograde endocannabinoid signaling
psiu04728  Dopaminergic synapse
psiu04750  Inflammatory mediator regulation of TRP channels
psiu04910  Insulin signaling pathway
psiu04912  GnRH signaling pathway
psiu04914  Progesterone-mediated oocyte maturation
psiu04917  Prolactin signaling pathway
psiu04920  Adipocytokine signaling pathway
psiu04926  Relaxin signaling pathway
psiu04930  Type II diabetes mellitus
psiu04931  Insulin resistance
psiu04932  Non-alcoholic fatty liver disease
psiu04933  AGE-RAGE signaling pathway in diabetic complications
psiu04935  Growth hormone synthesis, secretion and action
psiu04936  Alcoholic liver disease
psiu05010  Alzheimer disease
psiu05012  Parkinson disease
psiu05016  Huntington disease
psiu05017  Spinocerebellar ataxia
psiu05020  Prion disease
psiu05022  Pathways of neurodegeneration - multiple diseases
psiu05132  Salmonella infection
psiu05133  Pertussis
psiu05135  Yersinia infection
psiu05142  Chagas disease
psiu05145  Toxoplasmosis
psiu05152  Tuberculosis
psiu05161  Hepatitis B
psiu05162  Measles
psiu05166  Human T-cell leukemia virus 1 infection
psiu05167  Kaposi sarcoma-associated herpesvirus infection
psiu05169  Epstein-Barr virus infection
psiu05170  Human immunodeficiency virus 1 infection
psiu05171  Coronavirus disease - COVID-19
psiu05200  Pathways in cancer
psiu05208  Chemical carcinogenesis - reactive oxygen species
psiu05210  Colorectal cancer
psiu05212  Pancreatic cancer
psiu05231  Choline metabolism in cancer
psiu05415  Diabetic cardiomyopathy
psiu05417  Lipid and atherosclerosis
psiu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:psiu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    116741257 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116741257 (MAPK8)
   04012 ErbB signaling pathway
    116741257 (MAPK8)
   04014 Ras signaling pathway
    116741257 (MAPK8)
   04310 Wnt signaling pathway
    116741257 (MAPK8)
   04668 TNF signaling pathway
    116741257 (MAPK8)
   04068 FoxO signaling pathway
    116741257 (MAPK8)
   04071 Sphingolipid signaling pathway
    116741257 (MAPK8)
   04024 cAMP signaling pathway
    116741257 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116741257 (MAPK8)
   04137 Mitophagy - animal
    116741257 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    116741257 (MAPK8)
   04215 Apoptosis - multiple species
    116741257 (MAPK8)
   04217 Necroptosis
    116741257 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    116741257 (MAPK8)
   04530 Tight junction
    116741257 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    116741257 (MAPK8)
   04621 NOD-like receptor signaling pathway
    116741257 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    116741257 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    116741257 (MAPK8)
   04660 T cell receptor signaling pathway
    116741257 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    116741257 (MAPK8)
   04659 Th17 cell differentiation
    116741257 (MAPK8)
   04657 IL-17 signaling pathway
    116741257 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    116741257 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116741257 (MAPK8)
   04920 Adipocytokine signaling pathway
    116741257 (MAPK8)
   04912 GnRH signaling pathway
    116741257 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    116741257 (MAPK8)
   04917 Prolactin signaling pathway
    116741257 (MAPK8)
   04926 Relaxin signaling pathway
    116741257 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    116741257 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    116741257 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    116741257 (MAPK8)
   04722 Neurotrophin signaling pathway
    116741257 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    116741257 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    116741257 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116741257 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    116741257 (MAPK8)
   05231 Choline metabolism in cancer
    116741257 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    116741257 (MAPK8)
   05212 Pancreatic cancer
    116741257 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    116741257 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    116741257 (MAPK8)
   05161 Hepatitis B
    116741257 (MAPK8)
   05171 Coronavirus disease - COVID-19
    116741257 (MAPK8)
   05162 Measles
    116741257 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116741257 (MAPK8)
   05169 Epstein-Barr virus infection
    116741257 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116741257 (MAPK8)
   05135 Yersinia infection
    116741257 (MAPK8)
   05133 Pertussis
    116741257 (MAPK8)
   05152 Tuberculosis
    116741257 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    116741257 (MAPK8)
   05142 Chagas disease
    116741257 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    116741257 (MAPK8)
   05012 Parkinson disease
    116741257 (MAPK8)
   05016 Huntington disease
    116741257 (MAPK8)
   05017 Spinocerebellar ataxia
    116741257 (MAPK8)
   05020 Prion disease
    116741257 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    116741257 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116741257 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    116741257 (MAPK8)
   05415 Diabetic cardiomyopathy
    116741257 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    116741257 (MAPK8)
   04936 Alcoholic liver disease
    116741257 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    116741257 (MAPK8)
   04931 Insulin resistance
    116741257 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    116741257 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    116741257 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:psiu01001]
    116741257 (MAPK8)
Enzymes [BR:psiu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     116741257 (MAPK8)
Protein kinases [BR:psiu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   116741257 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 116741257
NCBI-ProteinID: XP_032463356
Ensembl: ENSPSNG00000013858
LinkDB
Position
16:37573375..37693249
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattc
acagtcctgaaacggtatcagaatttaaaacctataggttcaggagcccaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcagaatcaaactcatgctaagcgtgcttacagagagctagttcttatgaaatgtgta
aatcacaaaaatataattggccttttgaatgtttttacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgtcaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaaa
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgacacgctactacagagcacctgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtactgatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtacttttc
ccagctgactcggaacacaataaacttaaagccagtcaggcaagggatttgttatctaaa
atgctggtaattgatgcatctaaaaggatttctgtagatgaagctctccagcacccatat
atcaacgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatacaaagaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcatcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
ggacctctgggctgctgtagatga

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