KEGG   Phocoena sinus (vaquita): 116745009
Entry
116745009         CDS       T07759                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
psiu  Phocoena sinus (vaquita)
Pathway
psiu01521  EGFR tyrosine kinase inhibitor resistance
psiu01522  Endocrine resistance
psiu04012  ErbB signaling pathway
psiu04066  HIF-1 signaling pathway
psiu04140  Autophagy - animal
psiu04150  mTOR signaling pathway
psiu04151  PI3K-Akt signaling pathway
psiu04152  AMPK signaling pathway
psiu04211  Longevity regulating pathway
psiu04213  Longevity regulating pathway - multiple species
psiu04350  TGF-beta signaling pathway
psiu04371  Apelin signaling pathway
psiu04666  Fc gamma R-mediated phagocytosis
psiu04714  Thermogenesis
psiu04910  Insulin signaling pathway
psiu04931  Insulin resistance
psiu05163  Human cytomegalovirus infection
psiu05165  Human papillomavirus infection
psiu05170  Human immunodeficiency virus 1 infection
psiu05200  Pathways in cancer
psiu05205  Proteoglycans in cancer
psiu05207  Chemical carcinogenesis - receptor activation
psiu05210  Colorectal cancer
psiu05212  Pancreatic cancer
psiu05221  Acute myeloid leukemia
psiu05224  Breast cancer
psiu05225  Hepatocellular carcinoma
psiu05226  Gastric cancer
psiu05231  Choline metabolism in cancer
psiu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:psiu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    116745009 (RPS6KB1)
   04350 TGF-beta signaling pathway
    116745009 (RPS6KB1)
   04371 Apelin signaling pathway
    116745009 (RPS6KB1)
   04066 HIF-1 signaling pathway
    116745009 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    116745009 (RPS6KB1)
   04152 AMPK signaling pathway
    116745009 (RPS6KB1)
   04150 mTOR signaling pathway
    116745009 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116745009 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    116745009 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116745009 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    116745009 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    116745009 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    116745009 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116745009 (RPS6KB1)
   05205 Proteoglycans in cancer
    116745009 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    116745009 (RPS6KB1)
   05231 Choline metabolism in cancer
    116745009 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116745009 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    116745009 (RPS6KB1)
   05212 Pancreatic cancer
    116745009 (RPS6KB1)
   05225 Hepatocellular carcinoma
    116745009 (RPS6KB1)
   05226 Gastric cancer
    116745009 (RPS6KB1)
   05221 Acute myeloid leukemia
    116745009 (RPS6KB1)
   05224 Breast cancer
    116745009 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    116745009 (RPS6KB1)
   05163 Human cytomegalovirus infection
    116745009 (RPS6KB1)
   05165 Human papillomavirus infection
    116745009 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    116745009 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    116745009 (RPS6KB1)
   01522 Endocrine resistance
    116745009 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:psiu01001]
    116745009 (RPS6KB1)
Enzymes [BR:psiu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     116745009 (RPS6KB1)
Protein kinases [BR:psiu01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   116745009 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 116745009
NCBI-ProteinID: XP_032471123
Ensembl: ENSPSNG00000014972
UniProt: A0A8C9E635
LinkDB
Position
20:29795695..29834794
AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQAPVEYPMETSG
IEQMDVTTSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgaggcgacgacggaggcgggacggcttttacccagcgccggacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagtcgga
ccatatgaacttggcatggagcattgtgagaaatttgaaatctcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgagtacttggtaaaggg
ggctatggaaaggtttttcaagtacgaaaagtaacaggagcaaataccgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagactggtggaaaactctacctcatccttgagtatctcagcggaggagaatta
tttatgcagttagaaagagaaggaatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgcttaatcaccaaggtcatgtgaaactaacagattttggactatgc
aaagaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtctggga
gcattaatgtatgacatgctgactggagcacccccgttcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtcttggagctggtcct
ggggacgctggagaagttcaagctcatccattcttcagacatattaactgggaagaactg
ctggctcggaaggtagagcccccctttaaacctctgttgcaatctgaagaggatgtgagt
cagtttgattcaaagtttacacgtcagacacctgttgacagcccagatgactcaactctc
agtgaaagtgccaaccaggtctttctgggttttacatatgtggctccatctgtacttgaa
agcgtgaaagaaaagttttcctttgaaccaaaaatccggtcacctcgaagatttattggc
agcccacgaacacctgtcagccctgtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacggcaaatcctcaggcgcctgtggagtacccaatggaaacaagtgga
atagagcagatggatgtgacgacgagtggggaagcttcagcaccacttccaatacgacag
ccgaactccgggccatacaaaaaacaagcttttcccatgatctccaaacgaccagaacac
ctgcgtatgaatctatga

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