Phocoena sinus (vaquita): 116748753
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Entry
116748753 CDS
T07759
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu01521
EGFR tyrosine kinase inhibitor resistance
psiu01522
Endocrine resistance
psiu04010
MAPK signaling pathway
psiu04014
Ras signaling pathway
psiu04015
Rap1 signaling pathway
psiu04066
HIF-1 signaling pathway
psiu04068
FoxO signaling pathway
psiu04081
Hormone signaling
psiu04114
Oocyte meiosis
psiu04140
Autophagy - animal
psiu04144
Endocytosis
psiu04150
mTOR signaling pathway
psiu04151
PI3K-Akt signaling pathway
psiu04152
AMPK signaling pathway
psiu04211
Longevity regulating pathway
psiu04213
Longevity regulating pathway - multiple species
psiu04510
Focal adhesion
psiu04520
Adherens junction
psiu04550
Signaling pathways regulating pluripotency of stem cells
psiu04730
Long-term depression
psiu04913
Ovarian steroidogenesis
psiu04914
Progesterone-mediated oocyte maturation
psiu05200
Pathways in cancer
psiu05202
Transcriptional misregulation in cancer
psiu05205
Proteoglycans in cancer
psiu05214
Glioma
psiu05215
Prostate cancer
psiu05218
Melanoma
psiu05224
Breast cancer
psiu05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
116748753 (IGF1R)
04014 Ras signaling pathway
116748753 (IGF1R)
04015 Rap1 signaling pathway
116748753 (IGF1R)
04066 HIF-1 signaling pathway
116748753 (IGF1R)
04068 FoxO signaling pathway
116748753 (IGF1R)
04151 PI3K-Akt signaling pathway
116748753 (IGF1R)
04152 AMPK signaling pathway
116748753 (IGF1R)
04150 mTOR signaling pathway
116748753 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
116748753 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
116748753 (IGF1R)
04140 Autophagy - animal
116748753 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
116748753 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
116748753 (IGF1R)
04520 Adherens junction
116748753 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
116748753 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
116748753 (IGF1R)
04914 Progesterone-mediated oocyte maturation
116748753 (IGF1R)
09156 Nervous system
04730 Long-term depression
116748753 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
116748753 (IGF1R)
04213 Longevity regulating pathway - multiple species
116748753 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116748753 (IGF1R)
05202 Transcriptional misregulation in cancer
116748753 (IGF1R)
05205 Proteoglycans in cancer
116748753 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
116748753 (IGF1R)
05214 Glioma
116748753 (IGF1R)
05218 Melanoma
116748753 (IGF1R)
05215 Prostate cancer
116748753 (IGF1R)
05224 Breast cancer
116748753 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116748753 (IGF1R)
01522 Endocrine resistance
116748753 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
psiu01001
]
116748753 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
psiu04090
]
116748753 (IGF1R)
Enzymes [BR:
psiu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
116748753 (IGF1R)
Protein kinases [BR:
psiu01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
116748753 (IGF1R)
CD molecules [BR:
psiu04090
]
Proteins
116748753 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
116748753
NCBI-ProteinID:
XP_032477982
Ensembl:
ENSPSNG00000006634
LinkDB
All DBs
Position
2:complement(49886080..50196320)
Genome browser
AA seq
1368 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENHECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHD
GECMQDCPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEIVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKADKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNAIFVPRPERKRREVMQVANTTMSSRNRNTTVVDTYNITDPEELETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLIIALPIAVLLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAAR
NCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFG
VVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF
LEIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDR
HSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKKERALPLPQSSTC
NT seq
4107 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctatttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aacgactaccagcagctgaagcggctggagaactgcacggtgatcgagggctacctccac
atcctgctcatttccaaggctgaggactaccgcagctaccgcttccccaagctcacggtc
atcactgagtacctgctgctgttccgcgtggccggcctcgagagcctcggcgacctcttc
cccaacctcacagtcatccgtggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggatattgggctctacaacctgcgaaacattacccgtggggcc
atccggatcgagaagaatgctgacctctgctacctctccacggtggactggtccctaatc
ctggatgctgtgtccaataactacatcgtggggaataagcccccaaaggagtgcggggac
ctgtgcccggggacgatggaggagaagccgctgtgcgagaagacgaccatcaacaacgag
tacaactaccgctgctggaccacgaaccgctgtcagaaaatgtgcccgagcacgtgcggg
aagcgggcgtgcacggagaaccacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcccgacaacgacacggcctgcgtggcctgccgccactactactacgccggtgtctgt
gtgcccagctgcccgcccaacacctaccgcttcgagggctggcgttgtgtggaccgtgac
ttctgcgccaacatccccaacgctgagagcagcgattccgagggcttcgtgatccacgac
ggcgagtgcatgcaggactgcccatcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgcgaaggcccttgtcccaaagtgtgtgaggaagagaaaaagacaaagacc
attgattctgtcacttctgctcagatgctccaaggatgcaccatcttcaagggcaatcta
ctcattaatatcagacgtggcaacaacatcgcttcagaactggagaacttcatgggactc
attgagatcgtgacgggctacgtgaagatccgccactcccatgccttggtctccttgtcc
ttcctgaagaaccttcgccagatcctaggagaggagcaactagaggggaattactccttc
tacgtcctcgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagccgggaaaatgtactttgctttcaatcccaaattgtgtgtctccgagatctac
cgcatggaggaagtgacggggactaaagggcgccagagcaaaggggacataaacaccagg
aacaacggagagagagcctcctgtgaaagtgacgtcctgcacttcacctccaccaccacg
tggaagaaccgcatcatcatcacctggcaccggtaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaggaagcaccctttaaaaacgtcacagagtatgacggg
caggatgcctgtggctccaacagctggaacatggtagatgtggacctcccacccaacaag
gacgtggagcccggcattttactgcatggactgaagccctggacacagtatgccgtttac
gtcaaggctgtgaccctcaccatggtggagaatgaccacatccgtggagccaagagcgaa
atcttgtacattcgcaccaatgcttcagttccttccatccccctggacgtactctcagca
tcaaactcctcttctcagctgatcgtgaagtggaaccctccttccctgcccaacggcaac
ctgagctactacatcgtaaggtggcagcgccagccccaggacagctacctttaccggcac
aattactgctccaaagcagacaaaatccccatcaggaagtacgccgatggcaccatcgac
gttgaggaggtgacggagaatcccaagaccgaagtgtgtggtggggagaaagggccgtgc
tgcgcttgccccaagaccgaagccgagaagcaggccgagaaggaggaggccgagtaccgc
aaggtcttcgagaatttcctgcacaacgccatcttcgtgcccagacctgaacggaagcgg
agggaggtcatgcaggtcgccaacaccaccatgtccagccggaacaggaacaccacggtg
gtggacacctacaacatcacagacccagaggagctcgagaccgagtaccctttcttcgag
agcagagtggataataaggagagaactgtcatctccaacctccggccttttactctgtac
cgaatcgatatccacagctgtaaccacgaagctgagaagcttggctgcagcgcctccaac
tttgtctttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtgacc
tgggagccaaggcctgagaactccatctttttaaaatggccagaacctgagaatcccaat
ggattgattttaatgtatgaaataaaatatggatcacaagtcgaggatcagcgggaatgt
gtgtccagacaggagtacaggaagtatggaggggccaagctaaaccggctcaacccgggg
aactacacggcccggatccaggccacctctctctctgggaacgggtcgtggactgatcct
gtgttcttctatgtccaggccaaaacaacgtatgaaaacttcatccatctgatcattgct
ctgcccattgccgtcctgctgatagtaggagggttggttataatgctgtacgtcttccat
agaaaaagaaataacagcaggctggggaatggagtgctgtatgcctctgtgaacccggag
tacttcagtgcagccgatgtgtacgtgcctgacgagtgggaggtcgcccgggagaagatc
accatgagccgggagctggggcagggctcgttcgggatggtttatgaaggtgtcgccaag
ggcgtggtcaaggatgagcctgagaccagggtggccattaagacggtgaacgaagccgcc
agcatgcgcgagaggattgagtttctcaacgaggcctcggtgatgaaggagttcaactgt
caccatgtggtgcgcttgctgggcgtggtgtcccagggccagccgacgctggtcatcatg
gaactgatgacccggggggacctcaaaagttatctccggtctctgaggccagaaatggag
aataatccagtcctagcacctcccagcctaagcaaaatgatccagatggctggagagatt
gcagatggcatggcatacctcaacgccaataagtttgtccacagagacctcgctgcccgg
aactgcatggtggccgaagatttcacagtcaaaatcggagattttgggatgacgagagac
atctatgagaccgactattaccggaagggagggaaggggctgctgcccgtgcgctggatg
tcccccgagtccctcaaggatggagtcttcaccacgcactctgacgtctggtcctttggg
gtcgtcctctgggagatcgccacgctggccgagcagccataccagggcctgtccaatgag
caagtccttcgcttcgtcatggagggcggccttctggacaagccggacaactgtcctgac
atgctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttc
ctggaaatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttc
tactacagcgaggagaacaagccacctgagccagaggagctggacctagagccggagaac
atggagagtgtccccttggacccctcggcatcctcgtcctccctgccactgcccgacaga
cactcaggacacaaggccgagaacggtccgggccctggcgtgctggtccttcgagccagc
ttcgacgagagacagccttatgcgcacatgaacgggggccgcaagaaggagcgggccttg
cctctgccccagtcctcgacctgctga
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integrated database retrieval system
