KEGG   Phocoena sinus (vaquita): 116753887
Entry
116753887         CDS       T07759                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
psiu  Phocoena sinus (vaquita)
Pathway
psiu04010  MAPK signaling pathway
psiu04020  Calcium signaling pathway
psiu04022  cGMP-PKG signaling pathway
psiu04114  Oocyte meiosis
psiu04218  Cellular senescence
psiu04310  Wnt signaling pathway
psiu04360  Axon guidance
psiu04370  VEGF signaling pathway
psiu04380  Osteoclast differentiation
psiu04625  C-type lectin receptor signaling pathway
psiu04650  Natural killer cell mediated cytotoxicity
psiu04658  Th1 and Th2 cell differentiation
psiu04659  Th17 cell differentiation
psiu04660  T cell receptor signaling pathway
psiu04662  B cell receptor signaling pathway
psiu04720  Long-term potentiation
psiu04724  Glutamatergic synapse
psiu04728  Dopaminergic synapse
psiu04921  Oxytocin signaling pathway
psiu04922  Glucagon signaling pathway
psiu04924  Renin secretion
psiu05010  Alzheimer disease
psiu05014  Amyotrophic lateral sclerosis
psiu05020  Prion disease
psiu05022  Pathways of neurodegeneration - multiple diseases
psiu05031  Amphetamine addiction
psiu05152  Tuberculosis
psiu05163  Human cytomegalovirus infection
psiu05166  Human T-cell leukemia virus 1 infection
psiu05167  Kaposi sarcoma-associated herpesvirus infection
psiu05170  Human immunodeficiency virus 1 infection
psiu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
psiu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:psiu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116753887 (PPP3CA)
   04310 Wnt signaling pathway
    116753887 (PPP3CA)
   04370 VEGF signaling pathway
    116753887 (PPP3CA)
   04020 Calcium signaling pathway
    116753887 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    116753887 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    116753887 (PPP3CA)
   04218 Cellular senescence
    116753887 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    116753887 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    116753887 (PPP3CA)
   04660 T cell receptor signaling pathway
    116753887 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    116753887 (PPP3CA)
   04659 Th17 cell differentiation
    116753887 (PPP3CA)
   04662 B cell receptor signaling pathway
    116753887 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    116753887 (PPP3CA)
   04921 Oxytocin signaling pathway
    116753887 (PPP3CA)
   04924 Renin secretion
    116753887 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    116753887 (PPP3CA)
   04728 Dopaminergic synapse
    116753887 (PPP3CA)
   04720 Long-term potentiation
    116753887 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    116753887 (PPP3CA)
   04380 Osteoclast differentiation
    116753887 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116753887 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    116753887 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    116753887 (PPP3CA)
   05163 Human cytomegalovirus infection
    116753887 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116753887 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    116753887 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    116753887 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    116753887 (PPP3CA)
   05020 Prion disease
    116753887 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    116753887 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    116753887 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116753887 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:psiu01009]
    116753887 (PPP3CA)
Enzymes [BR:psiu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     116753887 (PPP3CA)
Protein phosphatases and associated proteins [BR:psiu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     116753887 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 116753887
NCBI-ProteinID: XP_032487742
Ensembl: ENSPSNG00000017541
UniProt: A0A8C9CL83
LinkDB
Position
5:120864712..121165132
AA seq 511 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAM
PSDTNLNSINKTLASETNGTDSNGSNNSNIQ
NT seq 1536 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccgtttcctccaagtcaccggcttacggcaaaagaagtgtttgataacgatgggaaa
cctcgtgtggatatcttaaaggcacatctcatgaaggagggcaggctggaagagagtgtt
gcattgagaataatcacagagggggcttcaattcttcgacaggaaaaaaatttgctggat
attgatgcaccagtcacagtttgcggggacatccatggacaattctttgacttgatgaag
ctctttgaagtgggcggatctcctgccaacactcgctacctcttcttaggggactatgta
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggctttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgcatggat
gcctttgactgcctgcccctggctgccctgatgaaccaacagttcctatgtgtacatggc
ggtttgtctccagagattaacaccttagatgatatcagaaaattagaccgattcaaagaa
ccacccgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcatacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatactccgagcc
catgaagcgcaagacgcagggtaccgcatgtacaggaaaagccaaacaacaggcttccct
tctctcattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgttttcacttggtccctgccatttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactggggtcagag
gaagatggatttgatggtgcaacggctgcagcccgcaaggaagtgatacggaacaagatc
cgagcgatcggcaagatggccagagtgttctccgtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcctgacacccacgggcatgctccccagtggagtgctctctggaggg
aagcaaaccctgcaaagcgctatcaaaggattttcaccacaacataagatcactagcttc
gaggaggccaagggcttagatcgaattaacgagaggatgccacctcgcagagatgccatg
ccctctgacaccaaccttaactccatcaacaagactctcgcatcagagactaacggcacg
gacagcaatggcagtaataacagcaatatccagtga

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