Phocoena sinus (vaquita): 116755091
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Entry
116755091 CDS
T07759
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
116755091 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
psiu03021
]
116755091 (SETX)
Enzymes [BR:
psiu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
116755091 (SETX)
5.6.2.5 RNA 5'-3' helicase
116755091 (SETX)
Transcription machinery [BR:
psiu03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
116755091 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
UvrD-helicase
AAA_19
AAA_30
AAA_22
SLFN-g3_helicase
ResIII
AAA_16
nSTAND3
NAT10_TcmA_helicase
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
116755091
NCBI-ProteinID:
XP_032489831
Ensembl:
ENSPSNG00000010504
LinkDB
All DBs
Position
6:4243170..4319565
Genome browser
AA seq
2684 aa
AA seq
DB search
MSTCCWCTPGGISTIDFLQHYASETHSSEFRTADEDLCYCLECVAEYHKARDELPFLHKV
LWELETSRLINHFEKAMKAEIGDDDELYIVDNNGEAQPFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDAANYKNYWLG
ICMLLTILEEQAMDSLLLGSNKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNKEIQNIRNSSMRTRFEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDTVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTMISSLSLHSVPSNSVQLACVQLIRS
LLKEGCQLGQQTLCKRFRDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKFKVPQ
CSTSVDLTSPGKMPPASYNKEESEQTRKKSKKDRHCLENSSPTFSKEPMKADACQVQESI
FSKANNAIEEDNEQTYIKDLKLKAHLSAELCLKPSSERLVNERTRGQVKISTGKHKSVKE
NSSYTPQNCTSRNGPEKVFDRGIITSTRLLTDSSNESLEKVSTSNEDFSLKGDALGKTSK
AKTKAHKDEICAKLSHVIKKQHRKSITLEENLTVSSIESFYSKKDTGGQKGDGFMYNLSL
GPNGILDDKNGEQKSENSLLLKKKQVQEEELGIFSTRELSCQILECHVGNKDLVSFTEMT
NIFVEKTPPFKDPVTGLESRDTEIIKSTAQFSSDLREQVLSISPKSDTLTDSQIDRDLHK
LSLVAQASVIKFPSDSTQKSLSQLQRKVKDDRRCFTANQNSVRETCSEQVIIISDSDEED
DEERIVGFKKHITQDKTCIEKECPEQHASIANTNVEQKVIREENAGSLLQFEESDSQFFE
FESPCEVFSVWQDRKPGNKNSVQENEENSCLTHAGDTTNDWGYGTDDVPEEVIKKAAEGI
EEHAEPHSSSISVEKFCEIEVKKPKRRRYQKAAMAEDPLRPSSPVKSEDQSDILNEGDVT
ENDFKSMDVRTTTPSSSVQRTTTVSLKRSPPKLRSYSKRVRRVSLSKTPKKTRSDTKTGQ
SKSSNYLSCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAPRRAFELSQRSLECLAQLRDH
GKTVGAVDTRKKTKLISPQTLSVRNNKKLLTSQDLQLRRQLRPKSQRNRQRCFDYQSTDT
TRAGPRGAQNSDKCVPESDTSDYSYKGGVEVTAKSKEKELIKCVSSETEPMKAKYVSQGA
DDTCLLNQCTSVVLNGEIPTNEIVVSTSGDPLGGGDLTVHHLDVAALREGDPESSSDIEE
DNIFLTQRDPEDMDLCSQMEKENDKLTEVVHGKDTVQVEEDSVSRPQLESLSSTKCKYKD
CVETLKNQGEYCSKHSEAKAADEDIFRKPGLPLSASKPSRPPTAKIFSSSSTSRIAGLSK
SLENTASLLPTLKNKSSGVQSVLKVPPVSLVSKKPVAEVKGLCNVLHSHTPNNSNRQGYK
VPFCENRSFSASPPVNVLLSAQSISDTFVKEVLKWKYEMFVNFDQCGPPSTLCQSISRPV
PVRFQDGGDYFNVFFPLMMLNTFETVAQEWISSPNKEKFHQLHLRKFPSEYKKHWEFVVY
LEECELAKQLHPKENDLVFLIPERLNGEEEDIEGNRMQDPYEYYCGYVHKFRRTSVMHNG
KSECSVSIQTQHNLPVNLNEFVKCLVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMD
FCTKDLLTTASEKIIAHLRDFNEDQKKAIETAYAMVKHSPAVAKICLIHGPPGTGKSKTI
VGLLYRLLTERRGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILQFKEKCKDKKNPL
GNCGDINLLRLGPEKSINAEVLKFSLDSQVNHRMKKELPSHIQEMHRRKEFLDHQLDELS
RQRALCRGGRELQRQELDEKIVKVSKERQELASKVKEVQGRPQKTQNTIILESHIICCTL
STSGGLLLEAAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTV
ISVKAQEYGYDQSMMARFYKLLEENVEHNVIGRLPVLQLTVQYRMHPDICLFPSNYVYNR
NLKTNRMTEAIRCSSDWPFQPYLVFDVGDGSEKRDNDSYVNVQEIKLVMELVKLMKDKKR
DFSYRNVGIITHYKAQKMMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANAM
QGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENYHWNQLIQDAQKRGAIVKTWDKNY
RQDAVKILKLKPVLQRSLTHPPAIAPEVSRPQGGVPSNKLDSEFAQMSVASSLYPSPSDS
KEGTVTVTANDPERPPIQDWLRDPRLLRRMGLGCEAKGKCLSELQPSSPQYPGATPPSGE
PGSPGRHQDPTSIGQQPPAKGAAVNNHRPHAQRDPPAASTDACTSKRKCAQEGEAVSHRR
ETRAFPEGDQETCGSLSHHTKRNSGWDERGLEEEDSSLKKRKLL
NT seq
8055 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacaccaggtggtatttccaccattgacttcctgcaacac
tatgcatccgagacccactccagtgaatttcgaacagctgatgaagacctctgctactgc
ttagagtgtgtggctgaataccacaaagcaagggatgaattgccattcttacataaggtt
ttatgggaattagaaacctcacgtctcataaatcactttgaaaaggccatgaaggcagaa
attggagacgatgacgagttatatatagtagacaacaatggagaggcacagccgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatttgcttttacatgagcgtgttaatgaactatgcgttgaagcactttgccggatg
gaacaagctaactgctcctttcaggtttttgacaaacatccagggatctatttgtttttg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaacttgggaaaa
gtggacagagatgattattatgacttacaggaggttttgacttgcctttttaaagtcatt
gagttggggcttttagaaagtccagacatttatacttcttctgtccttgagaagggtaaa
ctgattcttctgccttcacacatgtatgatgctgccaactacaaaaactattggttaggt
atttgcatgttgctgaccattcttgaggagcaagccatggattcactgttgttgggctca
aacaaacagaatgattttatgcaatcaatacttcacaccatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctt
ggatccaaggtctggggtcaacttattgatcctattgaggcatttcaaaccattatcaac
aatgtgagctacaataaagagattcagaatatacggaacagctctatgaggaccaggttc
gaaccagagtcatatttggatgatatggtgacttgcagccagattgtatacaattataac
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagctaatgtgcttcagtcagatatcggtcaagac
atgcgtgttcataacagcacgtttctgtggttcatcccttttgtgcagtccctcatggat
cttaaggatctgggtgtggcttatatagtggaggttattcatcatctgcattctgaagtc
aaagacgtcctcaaccagacagacgccgtgtgtgacacagtcactgagtttttccttctg
attttggtgtcagtgattgaactgcatagaaataaaaagtgtttgcatttgctgtgggtt
agttcccagcagtgggtggaagccgtcgtaaaatgtgccaagcttcccaccaccgcgttt
gcacggagttctgagaagtcatctggaaactgctccaaaggcacaatgatatcatctctg
tcattgcattcagtgccatctaactctgtacaacttgcttgtgtgcagctgatcagaagt
ctccttaaagaaggctgtcagcttgggcagcagactctttgtaagcgattccgggataag
ctcaacttattcctgcgaggaaatttatctttaggttggcagttgactagtcaggaaacc
catgagttacaaacttgtttaaagcaaattattagaaacataaaattcaaagtacctcaa
tgtagcacttctgtggatctgacttctccaggtaaaatgcctcctgcatcatataataaa
gaagaaagtgaacaaacaaggaagaagtctaaaaaagacaggcactgtctggaaaactcc
agcccaacattctctaaagaaccgatgaaagctgatgcatgtcaagtgcaagagagtatt
ttcagcaaagcaaataatgccatagaagaggataatgagcaaacttatataaaagatttg
aaactcaaagcccatctctcagctgagttgtgcttgaagccgagtagtgaaaggcttgtt
aatgaaagaactcgaggccaagttaaaataagtacagggaagcataagtctgtaaaagag
aattcctcatataccccacagaattgtacttcaaggaatggtccagaaaaggtatttgac
agaggaataataacatcaacacgtttgttgactgattctagcaatgagtctctggaaaag
gtgtctacatcaaatgaggatttctctttaaagggtgatgctcttggcaaaacctcaaaa
gcaaaaactaaggcacataaagatgaaatctgtgctaagttatcacatgtaataaaaaag
caacacaggaaaagtatcactttagaggaaaacctgactgtatctagcattgaaagtttc
tattcaaagaaggatacaggaggtcagaaaggagatggcttcatgtacaatctctcttta
ggccctaatggtattctggatgataaaaatggagaacaaaaatctgaaaacagtttattg
ctgaaaaagaaacaagtacaggaagaagagttaggcattttctctacccgtgaactcagt
tgtcaaatactagaatgtcatgttggtaataaagatttggtttcatttacagaaatgacc
aatatttttgtggagaaaacacctccctttaaagatcctgtgactggacttgaatcaaga
gatacggaaattatcaagagtactgctcagttttcttctgatttaagagagcaagtcctt
agcatcagtcctaagtctgacaccttaacagattctcagatagacagagacctccacaaa
ttatctttagtagctcaagccagtgttattaagttcccatcagattcaactcaaaaaagt
ttatcccagctacaaagaaaagttaaagatgatagaagatgtttcacagccaaccaaaat
agtgttagggaaacctgctctgaacaggtcattattatttcagattctgacgaagaagat
gatgaggaaagaattgtgggttttaagaaacacattacacaggataaaacatgcattgag
aaagaatgtccagagcagcacgcttcaatagctaacacaaacgtggaacagaaggtaata
agggaagaaaatgccgggtcccttttgcagtttgaggaatctgattctcagttttttgag
tttgaaagtccatgtgaagtgttttcagtttggcaagatcggaaaccaggcaacaagaat
tcagttcaagagaatgaagaaaattcgtgcttgactcatgcaggtgataccacaaatgat
tggggttatggtacagatgatgtacctgaagaggtcattaaaaaagcagcagagggcatt
gaggaacacgcagaaccacacagtagtagtatttctgttgagaagttttgtgagattgaa
gtaaaaaaacccaagagaaggcgatatcagaaagctgctatggctgaagatcctctaagg
ccttcatctcctgtcaaaagtgaggaccagtctgatattcttaatgagggagatgtgact
gaaaatgattttaaaagtatggacgtaaggactacaactcccagttcaagcgttcagaga
accactacggtttccctgaagaggtctccaccaaagcttcgctcttattccaaacgtgtt
aggagagtctcactttctaaaactcctaaaaaaacacgttcggataccaaaacagggcag
agtaaaagttcaaattacctaagttgtagaacaactcctgctatagtgccaccaaagaaa
tttcgccagtgtcctgaaccaacttcaacggttgagaaacttggtctgaaaaaggctcct
cgtagggcatttgagttgtcccagcgatctttggagtgtttagctcagttacgtgaccat
ggcaaaactgttggagcagttgatacccggaaaaagactaaattaatttctcctcagact
ctctctgtcagaaataataagaaactgctgacaagtcaagaccttcagctgcgaaggcag
ctgagacccaaatcacagcgtaacagacaaagatgttttgattatcagagtacagataca
acacgagcaggcccacgtggagcacagaattctgacaaatgtgtgccagaatcagatacg
tcagattatagctataaaggaggagttgaggtaactgctaaaagtaaggaaaaagagtta
ataaaatgtgtgtcttctgaaacagaacccatgaaagcaaaatacgtttctcagggagct
gatgacacttgtcttttgaaccagtgtacttctgtagtattaaatggagaaataccaaca
aatgaaatagttgtttctacctcaggggaccctttaggtggaggtgacctaacagtacat
catttagatgtggcagccttgagagagggagatcctgaatccagcagtgacatagaggaa
gataatatatttttaacacaacgtgatcctgaagatatggatttatgttcacaaatggag
aaagagaatgataaactcactgaagtagttcatggaaaagatacagtccaggtagaagaa
gattctgtgagtcggcctcagttggaatctttgagtagcacaaaatgtaaatacaaagat
tgtgttgaaacactgaaaaaccagggtgaatactgttcaaaacactctgaagctaaagca
gcagatgaagatatatttcgtaaacctggcttgcctctctctgcatctaaaccttcgaga
cctcccactgctaagatttttagctccagtagtacttcgcgaattgctggtctttccaag
tctttggaaaatacggcatcgctcttaccaactctgaaaaataagtcaagtggggtacag
tctgttttgaaagtaccgccagtctctctggtgtccaagaagccagtggctgaagtgaag
ggtttgtgcaacgttctccattctcatactccaaataattccaacaggcaaggctacaaa
gttccattttgtgaaaacagatctttttcggcttcccctccagtaaacgttctcttgtca
gcacagtccatctctgacaccttcgttaaagaggtcttaaaatggaaatacgaaatgttt
gtgaactttgatcagtgcggacccccgtcaactctgtgtcagtccatctcaagacctgtg
cctgtgagatttcaagatggtggagattattttaatgtgtttttccctttgatgatgctg
aatacttttgaaacagtggcacaggaatggatcagctctccaaacaaagagaaattccat
cagttgcatttacgaaaatttccttctgagtataaaaaacactgggagtttgtggtttat
cttgaggaatgtgaactagctaaacagcttcatccaaaggaaaatgatttggtgtttttg
attcctgaaagactaaatggagaggaggaggacatagagggaaatcgcatgcaagatccc
tatgaatattattgtggttatgttcataaattccgccgcacttcagtcatgcataatggg
aaatctgagtgttccgtttccatccagactcaacataatttaccagtcaatttaaatgaa
ttcgtgaaatgtcttgtaatcagctctctggtgactacacaaaggaagttgaaagccatg
tctttgctgagtggtcggaaccaactggccagagccgttctgaatccaaaccccatggac
ttctgtacaaaagatttactaactacagcatctgagaaaattattgcccacctaagagat
ttcaatgaagaccaaaagaaagcaatagaaactgcatatgccatggtgaaacactcccca
gcagttgccaagatctgtctgattcatggaccacccgggacaggaaaatcaaaaaccatt
gtgggcctcctgtaccgcctactgacagagaggaggggacattcagatgagaactccaat
gccaaaatcaaacaaaaccgtgtccttgtgtgtgcgccttccaatgcagctgttgatgaa
cttatgaaaaaaattatccttcaattcaaagagaagtgtaaagacaagaagaatcctttg
ggaaactgtggagatataaatttactacgtctaggtccagaaaagtctattaatgctgag
gtcctaaaattcagtttggacagccaagttaaccacagaatgaaaaaagaattaccttct
catattcaggagatgcatagaagaaaggaatttctagatcatcaactagatgaactttcc
cgccagcgtgctttatgccgaggtggaagggagctacagaggcaagaattagatgaaaaa
attgtcaaagtttcaaaagaaaggcaggagcttgcttctaaagttaaagaggttcaagga
cgcccacaaaagacacagaacaccatcatcttagagtcccacatcatctgctgcacactg
agcacgagtggtggtttgctgctcgaggctgctttccgtgggcaagggggtgtccccttt
agttgcgtcattgttgatgaggccggacagtcttgtgaagttgaaactcttactccgctc
atccatcgttgcaacaagctcatcctcgtaggagatcctaagcagctccctcccacagtc
atttctgtgaaggcccaggagtatggctacgaccagtcgatgatggcccgcttctacaaa
cttctggaagagaacgtggagcacaacgtgattggcaggctgcctgtcttacagctcacc
gttcagtacaggatgcacccagacatatgtctcttcccttctaattacgtttataacagg
aacttgaaaacaaatagaatgacagaggccattcggtgttcatctgactggccatttcaa
ccctacctcgtgtttgatgttggagatggttcagaaaagcgggataatgactcatacgta
aatgttcaagaaataaaactggtaatggaactagttaaacttatgaaagacaaaaaaagg
gatttttcttaccgaaacgttgggataataacccattacaaggcccagaagatgatgatt
cagaaggatttggacaaagagtttgatagaaaagggccagcagaagtagataccgtggat
gccttccagggtcgtcagaaagattgtgttattgttacatgtgtcagagcaaatgccatg
caaggttcaattgggtttctggcaagtttgcagagattgaatgtcaccatcacacgagcc
aagtacagcctcttcatcctgggacatttgaggaccctgatggaaaactatcattggaat
cagctgattcaggatgcgcagaagcgtggtgccattgttaagacttgggacaaaaactat
agacaagatgcagtgaagattctgaaactcaagcccgtactgcagagaagtctgactcac
cctcctgctatcgccccagaggtgtccagaccccagggcggagtgcccagcaacaagcta
gacagtgaatttgcccagatgtctgttgcttcttccctgtacccctcaccctctgactcc
aaagaaggcactgtcactgttactgcaaatgaccctgaaaggccacccattcaggactgg
cttcgggacccacgactacttaggaggatgggcttgggctgtgaagccaaagggaaatgc
ctcagtgagctgcagccctcgagcccccagtatcccggagcaacgcctccctctggagag
ccaggctcccccggaaggcaccaggatccgaccagtatcgggcagcagccccccgccaag
ggagctgctgtgaacaaccacagacctcacgcgcagcgcgaccctccagctgctagtacc
gatgcttgcacgagtaagagaaaatgtgcccaggaaggggaggcagtcagccacaggagg
gagaccagggccttccctgagggggatcaggagacgtgtggctctctgagccaccacaca
aagaggaactcaggctgggacgagagggggctggaggaggaggacagtagcttgaagaag
aggaagcttttatag
DBGET
integrated database retrieval system
