Phocoena sinus (vaquita): 116755295
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Entry
116755295 CDS
T07759
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu00790
Folate biosynthesis
psiu01100
Metabolic pathways
psiu01240
Biosynthesis of cofactors
psiu01523
Antifolate resistance
psiu04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
116755295 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
116755295 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
116755295 (FPGS)
Enzymes [BR:
psiu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
116755295 (FPGS)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
116755295
NCBI-ProteinID:
XP_032490423
Ensembl:
ENSPSNG00000010370
UniProt:
A0A8C9E326
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Position
6:complement(7939611..7958077)
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AA seq
580 aa
AA seq
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MSRARCHLRAALFLAAVSSRGATTGVAARRVLSAWPAPQEPGMEYQDAVRTLNTLQTNAN
YLEQVKRQRGDPQTQLEAMRLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWRLYHRLEETKDDSSCVSMPGYFR
FLTLMAFHVFLQEKVDLAVMEVGIGGAYDCTNIVKKPVVCGVSSLGIDHTGLLGDTMEKI
AWQKGGIFKSGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPLLTLGLEG
EHQQANAALALQLARCWLQQKGYRDTGELKASRPSLPGQLPLAPVFQPTSHMQHGLRDTE
WPGRTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALQSRERLGGGSEVLVLLFNSTGDR
DSAALLKLLQPCQFDYTVFCPNLTEVSSTDNADQQNFTVTLDQVLLRCLAHQQHWSRLHE
DQASPEPGGPAPLLLAPRPAHTHSASSLVFSCISHALQWISQGRDPVFQPPSPPRVLFAH
PVAGSGAVVLQEAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcacgctgccacctgcgcgcggctctcttcctggcagcggtttcttcgcgt
ggtgcaacaaccggggtcgcagcgaggcgagtattgagcgcgtggcctgcgccgcaggag
cccggcatggagtatcaggatgccgtgcgcacactcaacaccctgcagaccaatgccaac
tacttggagcaggtgaagcgccagcggggtgacccccagacacaactggaagccatgagg
ctgtacttggcacggagtgggctgcaggtggaggacttggaccaactgaacatcattcac
atcactgggaccaaggggaagggctccacctgtgccttcactgaacgtatcctccgaagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggtgcgtgagcggatc
cgaatcaatgggcagcccataagccccgagctcttcaccaagcacttctggcgcctctac
caccggctggaggagaccaaggatgacagcagctgtgtctccatgcctggctacttccgc
ttcctcacactcatggccttccacgtcttcctccaagagaaggtggacctggcagtgatg
gaagtgggcatcggcggggcttacgactgcaccaacatcgtcaagaagcctgtggtgtgt
ggggtctcctctcttggcatcgaccacactggccttctgggggacacgatggagaagatc
gcatggcagaaagggggcatttttaagagtggcgtccccgccttcactgtgctccagcct
gacgggcccctggcagtgctgagggaccgcgctcagcagatctcatgtcccctctacctg
tgcccaccactagaagccctggaggaaggggggccgctgctgaccctgggcctggagggg
gaacaccagcaggccaatgccgccttggccttgcagctggctcgctgctggctgcagcag
aagggctaccgggatactggagagctgaaggcgtccaggccaagcctcccggggcagctg
cccctggcacctgtgttccagcccacgtcccacatgcagcatgggcttcgggatacggag
tggccgggccggacgcagttgctgcggcggggcccccttacttggtacctggacggcgcg
cacaccaccagcagcatgcaggcctgcgtgcgctggttccgccaggcgctgcaaagccgc
gagaggctgggcggcgggtctgaggtccttgtcttgctcttcaactccactggggaccgg
gattccgcggccctgctgaagctgctgcagccctgccagtttgactataccgttttctgc
cctaacctgacagaggtgtcatccacagacaacgcagaccaacagaacttcacagtgacc
ctggaccaggtgctgctccgctgcctggcgcaccagcagcactggagccgcctgcacgag
gaccaggccagcccggagcctggtgggcctgcacccctgctgctggcaccccgcccagcc
cacacccacagcgccagctccctcgtcttcagctgcatttcccacgccttgcagtggatc
agtcaaggccgggaccctgtctttcagccacccagtcccccacgggtcctctttgcccac
cctgtggcaggcagtggggccgtcgtcctccaggaggctgctgccatccacgtgctggtc
acaggcagcctgcacctggtgggcggcgtgctgaagctgctggagccctccctgtcccag
tag
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