Phocoena sinus (vaquita): 116755422
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Entry
116755422 CDS
T07759
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
psiu
Phocoena sinus (vaquita)
Pathway
psiu01521
EGFR tyrosine kinase inhibitor resistance
psiu04062
Chemokine signaling pathway
psiu04081
Hormone signaling
psiu04148
Efferocytosis
psiu04151
PI3K-Akt signaling pathway
psiu04217
Necroptosis
psiu04550
Signaling pathways regulating pluripotency of stem cells
psiu04630
JAK-STAT signaling pathway
psiu04658
Th1 and Th2 cell differentiation
psiu04659
Th17 cell differentiation
psiu04725
Cholinergic synapse
psiu04917
Prolactin signaling pathway
psiu04920
Adipocytokine signaling pathway
psiu04933
AGE-RAGE signaling pathway in diabetic complications
psiu04935
Growth hormone synthesis, secretion and action
psiu05140
Leishmaniasis
psiu05145
Toxoplasmosis
psiu05152
Tuberculosis
psiu05161
Hepatitis B
psiu05164
Influenza A
psiu05167
Kaposi sarcoma-associated herpesvirus infection
psiu05168
Herpes simplex virus 1 infection
psiu05200
Pathways in cancer
psiu05207
Chemical carcinogenesis - receptor activation
psiu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
psiu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
psiu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
116755422 (JAK2)
04151 PI3K-Akt signaling pathway
116755422 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
116755422 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
116755422 (JAK2)
09143 Cell growth and death
04217 Necroptosis
116755422 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
116755422 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
116755422 (JAK2)
04659 Th17 cell differentiation
116755422 (JAK2)
04062 Chemokine signaling pathway
116755422 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
116755422 (JAK2)
04917 Prolactin signaling pathway
116755422 (JAK2)
04935 Growth hormone synthesis, secretion and action
116755422 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
116755422 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116755422 (JAK2)
05207 Chemical carcinogenesis - receptor activation
116755422 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
116755422 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
116755422 (JAK2)
05164 Influenza A
116755422 (JAK2)
05168 Herpes simplex virus 1 infection
116755422 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
116755422 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
116755422 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
116755422 (JAK2)
05140 Leishmaniasis
116755422 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
116755422 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
116755422 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116755422 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
psiu01001
]
116755422 (JAK2)
Enzymes [BR:
psiu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
116755422 (JAK2)
Protein kinases [BR:
psiu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
116755422 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
116755422
NCBI-ProteinID:
XP_032490755
Ensembl:
ENSPSNG00000020398
UniProt:
A0A8C9CUH0
LinkDB
All DBs
Position
6:55922641..56041545
Genome browser
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSSSPVHQNGDIPGNANSVKQIDPVLQVYLYHSLGKAEGDYLKFPTG
EYVAEEICVAASKACGVTPVYHSMFALMNETERIWYPPNHVFHIDESTRHNVLYRVRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLDIYSSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKSLEIELRSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKTGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKDENGEYNLTGTKKNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKI
RNEDLIFHESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDIYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKTLIHGNVCTKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYENRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQGKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRDLALRVDQIRDSMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcatgccttacaatgacagaaatggaaggaacatcctcatctcctgtacat
cagaatggtgatattcctggaaatgctaattctgtgaagcaaatagatccagtcctacag
gtctatctttatcattcccttggaaaagctgagggggattatctgaagtttccaactggg
gagtatgttgcagaagagatttgtgttgctgcttctaaagcttgtggagtcacacctgtg
tatcatagtatgtttgctttaatgaatgaaacagaaaggatctggtatccacccaaccac
gtcttccatatagatgaatcaaccaggcacaatgtactctacagagtcagattttacttt
ccttactggtattgtaatggcagcaacagaacctataggcatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggaggcatgat
tttttgcatggatggataaaagtacctgttactcatgaaacacaggaagaatgtcttggg
atggcggtgttagatatgatgagaatagccaaagaaaaggatcagacccccctggacatc
tatagctctgtcagctacaagacatttttaccaaaatgtgttcgagcaaagatccaagac
tatcatattttgacaaggaagcgaatacggtacagatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgatttt
cctgatattattgatgtcagtattaaacaagcaaaccaagaaggctcaaatgaaagcaga
attgtaactattcataagcaagatggtaaaagtctagaaattgaacttaggtcattaaga
gaagctttgtcttttgtgtcattaattgatggatattacaggttaactgcagacgcacat
cattatctttgtaaagaagtagcacctccaatggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgccatcagtaaactgaagaaaactggtaatcagact
ggactctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gttgagagagaaaacgtcattgaatataagcactgtttgattacaaaagatgagaatgga
gaatacaacctcactggtactaagaagaacttcagtaatcttaaagatcttttaaattgc
tatcagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgtccc
ccaaagccaaaagataaatcaaaccttctagtcttcagaaccaatggtatttctgatgta
ccaacctcaccaacattacagaggcataataatgtgaaccaaatggtgttccacaaaatc
agaaatgaagatttgatatttcatgaaagccttggccaaggaacttttaccaaaattttt
aaaggtgtaagaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaaacatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtaaaatttggatcactagatatatatctgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagctggcatgggcc
atgcattttctagaagaaaaaacccttattcatgggaatgtgtgcaccaaaaatattctt
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattctgcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaatttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataagcccctgagtgctttggattctcaa
agaaaactacagttttatgaaaataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattacgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac
atgttacctaatatgagaataggtgccctagggttttctggtgcttttgaagaccgagac
cctacacaatttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt
ggcagtgtggagatgtgccggtatgaccctctacaagacaacactggagaggtggtggct
gtgaagaagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaa
atccttaaatccttgcaacatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactat
ctccaaaaacataaagaacggatagatcataaaaaacttcttcagtacacatctcagata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacgagg
aatatattggtggagaatgaaaacagagttaaaataggagattttggcttaaccaaagtg
ttgccacaaggcaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctgg
tatgcaccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagcttt
ggagtggttctgtatgaacttttcacatatattgagaagagtaaaagcccaccagcggaa
tttatgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaa
ctcctgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatgta
atcatgacagaatgctggaacaataatgtaaaccaacgcccctctttcagagacctagct
cttcgagttgatcaaataagagacagcatggctggatga
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