KEGG   Phocoena sinus (vaquita): 116760326
Entry
116760326         CDS       T07759                                 
Symbol
KRAS
Name
(RefSeq) GTPase KRas isoform X1
  KO
K07827  GTPase KRas
Organism
psiu  Phocoena sinus (vaquita)
Pathway
psiu01521  EGFR tyrosine kinase inhibitor resistance
psiu01522  Endocrine resistance
psiu04010  MAPK signaling pathway
psiu04012  ErbB signaling pathway
psiu04014  Ras signaling pathway
psiu04015  Rap1 signaling pathway
psiu04062  Chemokine signaling pathway
psiu04068  FoxO signaling pathway
psiu04071  Sphingolipid signaling pathway
psiu04072  Phospholipase D signaling pathway
psiu04137  Mitophagy - animal
psiu04140  Autophagy - animal
psiu04150  mTOR signaling pathway
psiu04151  PI3K-Akt signaling pathway
psiu04210  Apoptosis
psiu04211  Longevity regulating pathway
psiu04213  Longevity regulating pathway - multiple species
psiu04218  Cellular senescence
psiu04360  Axon guidance
psiu04370  VEGF signaling pathway
psiu04371  Apelin signaling pathway
psiu04540  Gap junction
psiu04550  Signaling pathways regulating pluripotency of stem cells
psiu04625  C-type lectin receptor signaling pathway
psiu04650  Natural killer cell mediated cytotoxicity
psiu04660  T cell receptor signaling pathway
psiu04662  B cell receptor signaling pathway
psiu04664  Fc epsilon RI signaling pathway
psiu04714  Thermogenesis
psiu04720  Long-term potentiation
psiu04722  Neurotrophin signaling pathway
psiu04725  Cholinergic synapse
psiu04726  Serotonergic synapse
psiu04730  Long-term depression
psiu04810  Regulation of actin cytoskeleton
psiu04910  Insulin signaling pathway
psiu04912  GnRH signaling pathway
psiu04914  Progesterone-mediated oocyte maturation
psiu04915  Estrogen signaling pathway
psiu04916  Melanogenesis
psiu04917  Prolactin signaling pathway
psiu04919  Thyroid hormone signaling pathway
psiu04921  Oxytocin signaling pathway
psiu04926  Relaxin signaling pathway
psiu04929  GnRH secretion
psiu04933  AGE-RAGE signaling pathway in diabetic complications
psiu04935  Growth hormone synthesis, secretion and action
psiu04960  Aldosterone-regulated sodium reabsorption
psiu05010  Alzheimer disease
psiu05022  Pathways of neurodegeneration - multiple diseases
psiu05034  Alcoholism
psiu05160  Hepatitis C
psiu05161  Hepatitis B
psiu05163  Human cytomegalovirus infection
psiu05165  Human papillomavirus infection
psiu05166  Human T-cell leukemia virus 1 infection
psiu05167  Kaposi sarcoma-associated herpesvirus infection
psiu05170  Human immunodeficiency virus 1 infection
psiu05200  Pathways in cancer
psiu05203  Viral carcinogenesis
psiu05205  Proteoglycans in cancer
psiu05206  MicroRNAs in cancer
psiu05207  Chemical carcinogenesis - receptor activation
psiu05208  Chemical carcinogenesis - reactive oxygen species
psiu05210  Colorectal cancer
psiu05211  Renal cell carcinoma
psiu05212  Pancreatic cancer
psiu05213  Endometrial cancer
psiu05214  Glioma
psiu05215  Prostate cancer
psiu05216  Thyroid cancer
psiu05218  Melanoma
psiu05219  Bladder cancer
psiu05220  Chronic myeloid leukemia
psiu05221  Acute myeloid leukemia
psiu05223  Non-small cell lung cancer
psiu05224  Breast cancer
psiu05225  Hepatocellular carcinoma
psiu05226  Gastric cancer
psiu05230  Central carbon metabolism in cancer
psiu05231  Choline metabolism in cancer
psiu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
psiu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:psiu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116760326 (KRAS)
   04012 ErbB signaling pathway
    116760326 (KRAS)
   04014 Ras signaling pathway
    116760326 (KRAS)
   04015 Rap1 signaling pathway
    116760326 (KRAS)
   04370 VEGF signaling pathway
    116760326 (KRAS)
   04371 Apelin signaling pathway
    116760326 (KRAS)
   04068 FoxO signaling pathway
    116760326 (KRAS)
   04072 Phospholipase D signaling pathway
    116760326 (KRAS)
   04071 Sphingolipid signaling pathway
    116760326 (KRAS)
   04151 PI3K-Akt signaling pathway
    116760326 (KRAS)
   04150 mTOR signaling pathway
    116760326 (KRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116760326 (KRAS)
   04137 Mitophagy - animal
    116760326 (KRAS)
  09143 Cell growth and death
   04210 Apoptosis
    116760326 (KRAS)
   04218 Cellular senescence
    116760326 (KRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    116760326 (KRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    116760326 (KRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116760326 (KRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    116760326 (KRAS)
   04650 Natural killer cell mediated cytotoxicity
    116760326 (KRAS)
   04660 T cell receptor signaling pathway
    116760326 (KRAS)
   04662 B cell receptor signaling pathway
    116760326 (KRAS)
   04664 Fc epsilon RI signaling pathway
    116760326 (KRAS)
   04062 Chemokine signaling pathway
    116760326 (KRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116760326 (KRAS)
   04929 GnRH secretion
    116760326 (KRAS)
   04912 GnRH signaling pathway
    116760326 (KRAS)
   04915 Estrogen signaling pathway
    116760326 (KRAS)
   04914 Progesterone-mediated oocyte maturation
    116760326 (KRAS)
   04917 Prolactin signaling pathway
    116760326 (KRAS)
   04921 Oxytocin signaling pathway
    116760326 (KRAS)
   04926 Relaxin signaling pathway
    116760326 (KRAS)
   04935 Growth hormone synthesis, secretion and action
    116760326 (KRAS)
   04919 Thyroid hormone signaling pathway
    116760326 (KRAS)
   04916 Melanogenesis
    116760326 (KRAS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    116760326 (KRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    116760326 (KRAS)
   04726 Serotonergic synapse
    116760326 (KRAS)
   04720 Long-term potentiation
    116760326 (KRAS)
   04730 Long-term depression
    116760326 (KRAS)
   04722 Neurotrophin signaling pathway
    116760326 (KRAS)
  09158 Development and regeneration
   04360 Axon guidance
    116760326 (KRAS)
  09149 Aging
   04211 Longevity regulating pathway
    116760326 (KRAS)
   04213 Longevity regulating pathway - multiple species
    116760326 (KRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    116760326 (KRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116760326 (KRAS)
   05206 MicroRNAs in cancer
    116760326 (KRAS)
   05205 Proteoglycans in cancer
    116760326 (KRAS)
   05207 Chemical carcinogenesis - receptor activation
    116760326 (KRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    116760326 (KRAS)
   05203 Viral carcinogenesis
    116760326 (KRAS)
   05230 Central carbon metabolism in cancer
    116760326 (KRAS)
   05231 Choline metabolism in cancer
    116760326 (KRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116760326 (KRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    116760326 (KRAS)
   05212 Pancreatic cancer
    116760326 (KRAS)
   05225 Hepatocellular carcinoma
    116760326 (KRAS)
   05226 Gastric cancer
    116760326 (KRAS)
   05214 Glioma
    116760326 (KRAS)
   05216 Thyroid cancer
    116760326 (KRAS)
   05221 Acute myeloid leukemia
    116760326 (KRAS)
   05220 Chronic myeloid leukemia
    116760326 (KRAS)
   05218 Melanoma
    116760326 (KRAS)
   05211 Renal cell carcinoma
    116760326 (KRAS)
   05219 Bladder cancer
    116760326 (KRAS)
   05215 Prostate cancer
    116760326 (KRAS)
   05213 Endometrial cancer
    116760326 (KRAS)
   05224 Breast cancer
    116760326 (KRAS)
   05223 Non-small cell lung cancer
    116760326 (KRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    116760326 (KRAS)
   05170 Human immunodeficiency virus 1 infection
    116760326 (KRAS)
   05161 Hepatitis B
    116760326 (KRAS)
   05160 Hepatitis C
    116760326 (KRAS)
   05163 Human cytomegalovirus infection
    116760326 (KRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116760326 (KRAS)
   05165 Human papillomavirus infection
    116760326 (KRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    116760326 (KRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    116760326 (KRAS)
  09165 Substance dependence
   05034 Alcoholism
    116760326 (KRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116760326 (KRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    116760326 (KRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    116760326 (KRAS)
   01522 Endocrine resistance
    116760326 (KRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:psiu04131]
    116760326 (KRAS)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:psiu04031]
    116760326 (KRAS)
Membrane trafficking [BR:psiu04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    116760326 (KRAS)
GTP-binding proteins [BR:psiu04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    116760326 (KRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase ATP_bind_1 FeoB_N Septin
Other DBs
NCBI-GeneID: 116760326
NCBI-ProteinID: XP_032500957
Ensembl: ENSPSNG00000007396
UniProt: A0A8C9BJY4
LinkDB
Position
10:82690723..82729413
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGC
VKIKKCIVM
NT seq 570 nt   +upstreamnt  +downstreamnt
atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg
atacagctaattcagaatcactttgtggatgaatatgatcctacgatagaggattcctac
agaaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt
caagaggagtacagtgcgatgagggatcagtacatgaggactggggagggctttctttgt
gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaata
aaaagagttaaagactctgaagatgtacctatggttctagtaggaaataaatgtgatttg
ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct
tttattgaaacatctgcaaagacaagacagagagtggaggatgctttttatacattggtg
agagagatccgacaatacagattgaaaaaaatcagcaaagaagaaaagactcctggctgt
gtgaaaattaaaaaatgcattgtaatgtaa

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