Phocoena sinus (vaquita): 116763238 Help Entry 116763238         CDS       T07759                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism psiu  Phocoena sinus (vaquita) Pathway psiu04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:psiu00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     116763238 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:psiu03036]     116763238 (SYNE1) Chromosome and associated proteins [BR:psiu03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     116763238 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH SYNE1 KASH Motif Other DBs NCBI-GeneID:  116763238 NCBI-ProteinID:  XP_032506615 Ensembl:  ENSPSNG00000022337 LinkDB All DBs Position 12:13537455..13994523 Genome browser AA seq 8808 aa AA seqDB search MAASRTASRSSRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPS IVLGLMWTIILYFQIEELTSNLPQLQPLSSSTSSVDSVVSSETTSPPSKRKVATKIQGNA KKALLKWVQYTVAKQSGIEVKDFGRSWRSGVAFHSVIHAIQPELVDLEKVKGRSNRENLE EAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDVHSTGTDGQEIDREDM LILKETKAWIEQFERDLTRAQMTESNLQDKYQSFKHFRVQYEMKRTQIEHLIQPLHRDGK LSLDQALVKQSWDRVSSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITIQQVHEE TANTIQRKREQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPSDQLEDMAERFHFVSSTSE LHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRGSVELLLQNYMSFIENSKFFEQYE VTYQILKQTAEMYVKADGSVEEAENVMKFMNETTVQWRNLSVEVRSVRSMLEEVIANWDR YDNTVASLQAWLEDAEKMLNQSEHAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSR DLKQQLLLLNGRWRELFMEVKQYARADELDRMKKEYTDCVTTLSDFAAEALRKLSEPLEV SFINVKLLIQDLEDIEQRVPVMDAQYKMITKTAHLISKEISQEEANEMFATMSGLKEQLT KVKDCYSPLLYESQQLLLPLEELEKQMTVFYDSLGKIDEIMTVLEHEAQSSALFKQKRQE LLACQESCKKAMTQVEKGSHSVQKFVTLSNVLKHFDQTKLQRKIADGHVAFQNMVKRIGD WKKHVETNSRLMKKFEESRAELEKVLRIAQEGMEEKGNPEDLLKRHTEFFSQLDQRVLNA FLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIEVEKNMFLASVEE CRAELDRETKLVPQEGSEKIIKEHRIFFSDKGPHHLCEKRLQLIEDLCLKLPVRDAVRNT SETCHVTLKELRAAIDSTYAKLVEDPDKWKDYASRISEFSSWISAKETQLKGIKNKAIDT ANNGEVKCAVEEIRNGVTKKGETLSWLKSRLKILIEVSSENEAQKQGDELAKLSSSFKAL GTLLSEVEKMLSNFGDCVRYKEIVKSSLEGLMTGSKEVQEEAEKILDTENLFEAQQLLFH HQQKTKMINAKKRDVQRQIAQARQGEGGLPGRVQEELQKLESTLDNVEHSREKQERRIQV TLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTEGIAVQAE NLVKEASEIPLGPKNKQLFQRQAKSIQEQVKRLEDTLEEDIKTMEMVKNKWNHFGTNFET LSVWITEKEKELNDLETSSSAMDTQINQIKVTIQEIESKIGSITGLEEAAQSFAQFITTG ESARIKAKLTQIIRYWEELREHAQSLEGTILGHLSQQQKFEENLKKIQQTLSEFEDKLAD PIKICSSATETYKVLQEHMDLCQALESLTSTVAALSASARKVSHRDSSIQEAAALKQNYE CLLRQTKERQIVLEKLLTHWQRLEKELSTFLTWLERCEAIASPPEANISADRVKVENELQ LVQGLQNEIVSQASNYSNLLQLKESLFSVASKDDVKMMKLHLEHLDERWRDLPQIISKRI NFLQSVVAEHQQFDELLLSFSVWIKLFLSELQMTSEISIMDHQAARRRHKDHAAEVESKK GELQSLQGHLAKLGALGRAEDLHLLQGKAEDCYQLFEEASQVVERRQLALSHLAEFLQGH ASLSEVLHRLRQTVEATHSMNKKQSDLLERDLKAAIRDVKTLEATAISLDGLLTKAQYHL KSGSSEPRTSCRTTADHLCFELERIQNLLGTKQSEADALAVLKKAFQEQKEELLKSIEDI EERTDREQLKELTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVVFAPEVD REINRLEVTWDDTKKLIHENQGLCCGLIDLMREYQNLKSAVTKVLENASNVIVTRTTVKD QEDLKWALAKHATAKHEMCNKQKELDDFTSKGKQLLSELKKIHSGDFILVKTDMESTVDK WLDIAEKIEENMDRLRVGLSIWDDVLTSKDEIDGWTNNSVPQLTKSVSNLNNSLKAEEFL KEFESEVRKRALRLEELHSKVNDLKELTKNPETPPDLQFIEADLRQKLEHAKEIAEEAKG TLKEFTSQSAQVEKFINDIATWLTKLEESLINCAQTETCEGLKKVKEIQKELQSQKSNIS ATQENLNSLCRKYHSVELERLGSEVTGLMKRHEAVSQSCCKTQASLQDSLEEHFSESMQE FQEWFSGIKAAAKESSDRTGDSKVLEAKLHDLQNLLDSVSDGQSKLDAVTREGQTLYAHL PKQIVGSIQEQITKANEEFQAFLKQCLKDKQALQDCALELGSFEDQHRKLNVWIHEMDER LSTEDLGESKQHIPEKKNEVHKIEMFLGELLAARESLDKLSQRGQLLSEEGHGAGKEARL CSQLLTNYQNLLRRTKEKLRSCQMALQEHEALEEALQSMWSCVKDMQDRLACAESTVGGR DALERQLSQVQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQKVIETQLQTLKDVWADI MSSSVRAQSTLESVISQWNDYLERKNQLEQWMESVDQKAEHPLQPQPGLKEKFSLLDHFQ SVVSEAEDHAAVLQRLTAKARELYQKTEDESFKEAAQEELKTQFNDIMTISKEKMRKVEE IVKDHLMYLDAVQEFTDWLHSAKEDLHRWSDMSGDSSATQKKLSKIKELLDSREIGATRL SRVESLAPAVKQNTSASGCELLDTEMQALRADWKQWEDSVFQTQTSLENLVSQMALSEQE FSGQVAQLEEALGQFGALLTSWAQQLALLEGRNTDQELVECWQKGREILDALQKAEPQTE DLKSQLNELCRFSRDLSTYSRKVSGLIKEYNCLCLQASKGCQNKEQILQQRFRRAFKDFQ QWLVHAKITTAKCFDIPQNISEVSASLQKIQEFLSESENGQHKLNTMLSKGELLSTLLTK EKASGIQAKIATAKEDWKDFHSNLHQKVSALENLKTQMKDFEVSAEPVQDWLSKTEKMVH ESSKRLYDLPAKRREQQKLQSVLEEINCYEPQLHRLKEKAQQLWEGHAASRSFTHRVSQL SSQYLALSNFTKEKVSRLDRIVAEHNQFSLGIKDLHDWMTDAVHMLDSYCHPTSDKSVLD SRVLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPAIQQQLRTVKAMWASLLSAV IRCKSQLEGALSKWTSYQDDVRQFSSWMDSVEASLNESERQYAEVREKTAALGKVKLLNE EVLSHSSLLETIEVKGAGMTEHYVTQLEFQDLQERYRDIRERTKEAVTKSEKLVRLHQEY QRDLKAFEAWLQQEQEKLDRYSVLEGDAHTHETMLRDLQELQVHCTEGQALLNSVLHARE EVIPSGIPQTEDRALESLRQDWQAYQQRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKAM EDKVSLRSGRQSNRAAKEIQLHQMKKRHEEITAYRDEVEEVGARAQEILDESHVSSQMGF QATQLTSRYQALLLQVLEQIKFLEEEIQSLEESELSLSSYSDWYSSTHKNFNNVAAKIDK VDKVTMGKKMKTLEGLLKDMEKGQSLLKSAREKGERALTYLEDGEAETLRKEIHDHVEQL KELTSAVRKEHMTLEKGLHLTKEFSDKYKALTQWIAEYREILYIPEEPKMELYEKKAQLS KYKSLQQTVLSHEPTVKSVREKGEALLELVQDVTLKDKIDQLQSDYQNLCSAGKEHVCRL EVKVRDHEDYNSELQEVEKWLLQMSGRLVAPDLMETSSLETVTQQLARHKAMMEEIAGFE DRLNNLKIKGDSLISQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRVYESLEQELQK HVSRQDTLQQCQAWLSAVQPDLKPSAHPPVSRAEAVKQVKHFRALQEQARTYLDLLCTMC DLSNSSVKTTAKDIQQTEQMIEQRLAQAQNLTQGWEEIKHMKAELWIYLQDASQQLQNMK RSHSELELNIAQNMVSQVKDFVKKLQCKQSSVTTITEKVDELTKKQESPEHKEISHLNDQ WLDLCLQSNNLCLQREEDFQRTRDYHNCMSVVEVFLEKFTTEWDNLARSDTESTAIHLEA LKKLALALQERKQAIDDLKEKKQNVIEHLNVDDKELVKEQTSHLEQRWFQLEDLVERKIQ VSVTNLEELSVVRSRFQELMDWAEEQRPSIAEALKQSPPPDMAQNLLMDHLAICSELEAK QMLLKSLTKDADRVMADLGLNERQIIQKVLSDAQRHVNSLSDLVGQRRKYLNKALSEKTQ FLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVRTCKSAQASLKTYQNEVTGLWAQG RELMKGVTEQEKSEVLGKLQELQSVYDTVLQKCSHRLQELEKNLVSRKHFKEDFDKACHW LKQADIVTFPEINLMNESAELHTQLAKYQHILEQSPEYENLLLTLQRTGQAILPTLNEVD HSYLNEKLNALPLQFNVIVDLAKDKFYKVQEAILARKEYDSLIELTTQSLCDLEDQFSKV SQVPSDLSVEEALCLQDGCRALGGEVAALAEAVDELNQKKESFRSTGQPWQPDRMLHLVT LYHRLKRQTEQRVSLLEDTTSAYQEHEKMCHQLEKQLEVVRTEQAKVNEETLPAEEKLKV YHSLAGSLQDSGILLKRVTVHLEDLVPHLDPSAYEKAKHQIQAWQEELKLLTSAIGVTVT ECESRMVQSRDFQTELSRSLDWLRSVETALSGPLCLDLNLRDVQEEIRKVQIHQEEVQSS LRIMNALSNKEKENFTRAKELISADLQHTLAELSELDGALQEALRTRQATLTQMYSQCQR YYQVFQAANDWLDDAHEILQLTGNGLDVESAEESLKNHMEFFSTEDQFHSNLEELQGLVA NLDPLIKPSGKEDLAQKMASLEEKSQGTIQESHIQLDLLQRCATQWQDYQKAREEVIDLM NDAEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEGKASELERTGNGAS KATMSRSMTAVWQRWNRLRAVAQDQEKILEDAVDEWKSFNNKVKKATEMINKLQDKLPGS SAEKASKAELLTLLEYHDTFILELEQQQSGLRMLEQQALSMLQDGAELSPGEEPPTVQEI TAMQDRCLNIQEKVKKNRKVLRQELKEREVVETQINSVKSWVQETKEYLGNPTIGIDAQL EELKILLTEATNHRQNIEKMAEEQKNKYLGLYTILPSELSLQLAEVALDLGTIHDQIQDK IKEVEQSKAMSQEFSQQIQKIAKDLTTILTKLRAKTDNLVQAKTDQKVLGKELDVCNLKL MDLGEAVQKFSEQNGQLGKPLAKKIGKLTELHQQAIRQADNRLSKLSQAASHLEEYNEML ETILKWIEKAKVSVHGKIAWNSASQLREQYISHQTMLEESEEIYNNLEAMTGKLQYLSSV YHTEKMSQQVADLGRETEGLRQRIRIRLQNLHDAAKDMKKFETELRNLQIALEQAQTALT SPEVGRLSLKEQLSHRQHLLSAMESLKPKVHAVQMSQSALRIPEDVVTSLPLCHAALRLQ EGASRLQHTAIQQCNIMQEAVVQYEQYEQEMQHLQELIEGAHREIEDKPVATSDIQELQA QISRHEELAQKIKGYQEQIASLNSKCKMLTVKAKHATMLLTVTDVDRLAEGMENLDGELL PATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASINQDI AYYQALSAESLQTDASRIPPSILPPQELCEPSLEPSATAKLDDLQRSWETLKNVISEKQR TLYEALERQQKYQDCLQSVSTKMEAIEMKLSESPEHGRSTESQMAEHQSSPQALMDEILM LQEEISELQSALAEELVSDPPESDPSEQLPLQSTLAVLAERMSTIKMKASGKRQLLEEKL NDQLEEQRQEQALQRYRCEADELDHWLSSTKATLDVALGSPKEPMDMEAQLVDCQNMLVE IEQKVMALSELSVHNENLLLEGKAHTKDEAEQLSVKLRTLKESLLELQRALHDKQLHIQG TAQEKEESDADLAATQSPGVQEWLAQARTAWTQQRQSSLQQQKELEQELAEQKSLLQSVA SLGEEILTQHSAAEASGGVGEKPDVLSQELGMEGQKSPAEDQMRMKWESLHQEFSTKQKL LQNVLQHEPEQVLYSRPNRLLSGVPLYKGDGQPQDKSAVTSLLDGLNQAFEEVSAQGGGT KRQNTDLEQKLYDGVSATSTWLDDVEDRLFAATALLPAEAETCLFNQETLAKDIKEMSEE MDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQND LKVLFASLADHKYIILQKLANVFEQPVAEQIEAIQQAEDGLKELDAGITELKRRGDKLQI EQPWVQELSKLQDMYDELMMTTGSRRGGLNQNLALKGQYERALQDLADLLETGREKMAGD QKIIVSSKEDIQQLLDKHKEYFQGLESHMILTETLFRKVISFAVLRETQFHTDLMEQASA VLKGAHKRGVELEYILETWSHLDENQRELSRQLEVVETSIPTVGLVEESEDRLIDRITLY QHLKSSLNEYQPKLYQVLDDGKRLLISVSCSDLESQLNQLGEHWLNDTNKVSKELHRLET ILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAK STLKSSVLSTGNQLLRLKKVNTAALRSELSHIDGQWTDLLTNIPTVQEKLHQLQMDKLPS RRAISEVMAWISLMENVIQMDEESIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQ SVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQ GLKTWFETQEKRLKQQERIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNK KEEASGIVTSTLQDLNHTWANLDHMVGQLKILLKSVLDQWSRHKVAFDEINSYLMEARYS LSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQEKSLQKFGSITNQLLKESHPPVTETLTDT LKEVNMRWNHLLEEIAEQLHASKALLQLWQRYKDYSKQCAATVQQQEGRTNELLKAATDK DIADDEVATWIQDCNDLLKGLRTVKDSLFVLHELGEQLKQQVDASAASAIQSDQLCLSQH LCALEQALCKQQAMLQAGVLDYETFTKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQER MEELKGQMLKFSSMVPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISTQTTERFSKLQ SFLLQHQTFLEKCETWMDFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILH SIIVDGQHLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYQEMA EKLRKWLVEVSYLPVSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLL LSADGAAEAALQAELAEIQERWRSASVHLEEQKKKLAFLLQDWEKCENGIADSLEKLRTF KKRLSPPLPDHHDGLHAEQMRGKELENAVGSWTDDLARLTMLKDAVCAYISADDISILNE RMELLQRQWEELCHQLSLRQQQVSERLNEWAVFSEKNKELCEWLTQMESKISQNGDILIE EMIEKLRKDYQEEIAIAQENKIQLQQMGERLARASHESKASEIEYKLGKINDRWQHLLDL MAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCDSEEIQKKLNKQQEL QRDIEKHSTGVASVLNLCEVLLHDCDACATDAECGSIQQATRNLDRRWRNICAVSMERRL KIEETWRLWQKFLDDFSRFEDWLKCSERVAAFPSSSGVLYTVAKDELKKFEGFQRQVHET LTQLELINKQYRRLARENRTDSACSLKHMIHEGNQRWDNLQKRVTSILRRLKHFIGQREE FETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQ LIEKSEPLDATFIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEEA AALSDLHWRDTSADSALSPQPASNPSLSLAQPLQGERSGRDTPASVDSIPLEWDHDYDLS RDLESAVSRTLPSEDEEGQEDKDFYLRGAVGLSDVTIPESPEAYVKLTESAIRNPSGDPS TLESQIQQLGQALDDSHFQMQQMENIIHSKTPAGPELDSSYRGYMKLLGECSGSIDSVKR LEHKLTEEEEHFPGFVNLNSTETQTAGVIDRWELLQAQALSKELRMKQNPQRRQRFHSDL GRVLTWLQETEDDLEQLQRRQRSTDIQPIALQIKKLKELQKAVDHHKAIILSINLCSSEF TQPGSEESQDLQGRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQDFHEMSHGLLLMLENI DRRKNEIVPVDSNLDAEILQDHLKQLTQIRHELLESQLKVASLQDMSRQLLVNAEGTDCL EAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDMSSSQQDLSSWSSADELDTSGSVSPTSG RSSPNRQKTPRGKCSLSQPGPSVNSPHSRSIKGGSDSSLSEPRPARSGRAFLFRVLRAAL PLQLLLLFLIGLACLVPMSQEDYSCALSNNFARSFHPMLRYTNGPPPL NT seq 26427 nt NT seq  +upstreamnt  +downstreamnt atggcagcctccaggacagcctcgcggtcttctcgggacatcgccaacgtgatgcaaagg ctgcaagatgagcaagagatagtacaaaaacgtacttttacaaaatggatcaactctcat ctggccaagcggaaacccccaatggtggtagatgatctttttgaagacatgaaagatggt gtgaagctgctcgctctgctggaggtcctctctgggcagaaactgccgtgtgaacaagga cgccggatgaagcgaatccatgctgtggcgaacattggcacggcactcaagttcctggaa ggaaggaagattaaattagtcaacattaactccactgatatagctgatggccgaccctcg atagttctcggactgatgtggaccattattctgtatttccagattgaggagttgaccagc aacttaccacagctgcagcctctgtccagcagcacatcctccgtggacagcgtggtcagc tctgagaccaccagccccccaagcaaacggaaggtggccaccaagatccaaggaaatgct aagaaggctttattaaagtgggtccagtacacagtcgccaagcagagcggaatagaagta aaagacttcgggaggagttggagaagtggagtggcctttcattcagtcatccatgctatt caaccggaactagtggacttggagaaggtgaaaggaagatctaaccgggaaaacctggag gaggctttcactattgctgaaacggagctgggaatcccgagactcctagatcccgaagat gttgatgtggataaaccagatgagaagtctattatgacctacgtagcccagtttctgaaa cattatcccgacgttcacagtacaggcactgatgggcaagagattgatagagaagacatg ctaattttgaaggaaacgaaagcttggatagaacaatttgaaagagatttgacaagggca cagatgacagaatcaaatttgcaggataaatatcagtcctttaagcacttcagagttcaa tatgaaatgaaaaggacacagattgaacacttgatacaaccattacacagagatggtaaa ttgtcacttgaccaggcgttggtaaaacagtcctgggatagagtgtcctctaggctgttt gattggcatatacaacttgataagtctcttcctgcacctctgggcaccataggggcctgg ttatatagagcagaggtggccttgagagaggaaataaccattcagcaggttcatgaagaa acggccaacacaatacaacggaaacgtgagcaacacaaggatctgcttcaaaacacagat gcccacaaaagagcattccatgaaatctaccgaaccaggtctgttaacgggatcccagta ccatctgatcaattagaggacatggctgagaggtttcattttgtttcctccacatcagag ctacacttaatgaaaatggaatttctagaattaaagtaccgtctgctctcactgctggtt cttgcagagtcaaagctgaagtcttggatcatcaagtatgggaggagaggctcagtggag ctgcttctgcagaactacatgtcttttatagaaaatagcaagttctttgaacaatatgaa gtgacataccagatcttgaagcagacagctgagatgtacgtcaaagctgatggttcagtg gaagaggctgagaacgtgatgaaattcatgaatgaaaccactgtccagtggaggaacctc tcagtggaagtcagaagcgtgcgcagcatgctggaagaagtcattgccaactgggaccga tatgacaataccgtggctagtcttcaggcttggctagaggatgctgagaaaatgctaaat cagtcagaacatgccaaaaaggatttttttcgaaatctgcctcattggatacagcagcac acggccatgaacgatgctggcaattttctgattgaaacatgtgatgagatggtgtcccgt gatctcaaacagcagttactgttgctaaatggacgatggagagagttgtttatggaagtc aagcaatatgctcgagctgatgagttggacagaatgaagaaagaatacacagattgtgtt actaccctgtctgactttgcagctgaagcccttaggaaactttcagagcccttagaagtc tcttttattaatgtcaagttattaattcaagacttagaggatattgagcagagggtgcct gtgatggatgctcagtataagatgattacaaagacagcacacctcattagcaaagagatc tcccaagaagaagctaacgaaatgtttgcaaccatgtctgggctcaaagagcagctaacc aaggtcaaagactgttactctccactcctttatgagtctcagcagctgctgttaccgttg gaagaattagaaaagcagatgacggtcttttatgactcacttgggaaaatcgatgaaatt atgacagttcttgagcacgaggcacaatcaagtgctctttttaaacagaaacgtcaggaa ctgttagcttgtcaagaaagctgtaagaaagccatgacccaagttgagaaaggcagtcat agtgttcagaagtttgtgactttgagcaacgtgctaaagcattttgatcagacaaagcta cagagaaagattgcagatgggcacgttgcttttcagaatatggtaaagagaattggagat tggaagaaacatgtggaaaccaacagccgcttgatgaagaagtttgaggagtctcgagca gagttggagaaggtgctgaggatcgctcaggagggcatggaggaaaaggggaatccagaa gacctcctgaagagacacaccgagtttttcagtcagctggatcagagggtgctcaatgct ttcctgaaagcttgtgatgagctcaccgacattctcccggagcaggagcaacagggcctg caggaagccgttagaaagctccacaaacagtggaaggatcttcaaggagaagctccatat catttgcttcacctgaagatcgaggtggagaagaacatgttcttagcgtctgtagaagaa tgcagagctgagctggaccgagagaccaagctggtgccccaggaaggcagcgaaaagatc atcaaagagcacaggatcttcttcagtgacaagggtcctcatcatctctgtgagaaaagg ttacagcttattgaagacctgtgtctgaaactcccagtccgggacgctgtacggaacacg tctgagacctgtcacgtgaccctcaaggagctcagagccgccattgacagcacctacgcg aagctggtggaagacccagacaagtggaaggactacgccagcagaatttctgagttctcc tcttggatatctgcaaaggagacccagttgaaggggattaagaacaaggccatcgatact gccaacaacggagaggttaaatgtgctgtagaggagatcagaaatggtgttaccaaaaaa ggcgagactctcagctggctgaaatccaggcttaaaattttgattgaagtctcttctgag aatgaagcccaaaagcaaggagatgagctggcaaaattatctagttccttcaaggccctt gggactttgttgtcagaggttgaaaagatgttaagcaactttggagactgtgtccggtac aaagaaatagtcaaaagttcccttgaagggttaatgactggctctaaggaagtccaggaa gaagccgagaagatcttggacactgaaaatttgtttgaagcacagcaactactctttcat caccagcaaaagacaaagatgatcaatgcaaagaagagggatgtgcagcggcagatcgca caggctcggcagggagaaggtgggctgcctggccgagtccaagaggagctgcagaagcta gagagcaccctggacaacgtggagcacagccgggagaagcaggagcgccgcatccaggtc acattaagaaaatgggagagatttgaaacaaacaaagagacagtggtcagataccttttt caaacaggttccagccacgagcgcttcttgagttttagcagtttggaaagcttatcttca gaattggaacagacaaaggagttttctaaacgaacagaaggtattgcagtccaggctgag aatcttgtgaaggaagcttcagagatcccacttgggcccaagaataagcagctgtttcaa cggcaggccaagtcaatccaagagcaagtcaaaagattagaagacacacttgaagaagat attaaaaccatggaaatggtgaaaaacaagtggaatcattttggcactaattttgagacc ctgtccgtctggataactgagaaagaaaaagaactcaatgacttggaaacttcgtcatct gccatggacacacaaatcaaccaaattaaggtcacgattcaggaaatagaaagtaagatc ggcagcattacaggactagaagaagcagctcagtcttttgctcagtttattaccactgga gaatctgctcgaatcaaagccaagttaacacagataataagatactgggaagaactccga 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cggatccccgaggacgtcgtcaccagcttgccgctgtgccacgcagctctgcgcctgcag gagggggccagccggctccagcacacagccatccagcagtgcaacatcatgcaggaggct gtggtgcagtatgaacaatacgagcaagaaatgcagcacctccaggagctcatagaagga gctcacagagagattgaggacaagcctgtggccaccagcgacatccaggagctgcaagcc cagatttcccggcacgaggagctggctcagaaaatcaagggctaccaggagcagatcgct tctttgaactccaagtgcaagatgctgaccgtgaaagccaagcacgccaccatgctgctg acggtgaccgacgtggaccggctggcggaggggatggagaacctggacggggagctcctc cccgcgacctcggcccacccctctgtggtcatgatgactgcaggtcgctgtcacactttg ctgtcaccggtcactgaggagtctggggaggagggaaccaacagtgagatttcctctcca cctgcctgtcgctccccttcacctgtggctaatacagatgcttccattaaccaggacatc gcttattaccaagccttgtctgccgagtcgttgcagacggatgcctccaggattcccccc agcattctgccaccccaagagctctgtgaaccaagtctggagccatctgccactgctaaa ctggatgatttacaacgctcttgggaaaccttaaagaatgtgatcagcgaaaagcagcgc acactctacgaagcgttggaacgccaacagaagtaccaggactgcctccagtccgtctcc acgaaaatggaggctatcgagatgaaactcagtgaaagtccggagcacggcaggagtacc gagagccagatggccgaacaccagtcttccccgcaggcactgatggatgagattctcatg cttcaagaggaaatcagtgagctgcagtcggccctcgcggaggagctggtgtctgacccc ccagagtccgacccttcggagcagctgcccttgcagtccacgctcgctgtcttagcggag cgaatgtccaccatcaagatgaaggcatcagggaaacgacagcttttggaggagaagtta aatgatcagctggaggaacagagacaggagcaggccctgcagaggtatcgctgtgaagcc gatgagctggaccactggctctctagcactaaggccactctggacgttgcactggggtca cccaaggagcccatggacatggaggcccagctggtggactgccagaacatgctggtggaa atagaacagaaggtgatggccttatcggagctctcagtccacaatgaaaacctgctgctg gagggcaaggctcacacaaaggacgaggcggagcagctgtcggtgaagctgagaaccctc aaggagagcctcctggagctgcagagagcgctgcacgacaagcagctgcacatccagggg acagcccaggagaaggaggagagcgatgctgacctggctgccactcagagccccggcgtt caggaatggctggctcaagctcggactgcgtggacccaacagcgacagagcagcctccag caacaaaaagagttggaacaggaattagcagagcagaagagcctcctccagtcagtagcc agtcttggagaggaaattctaacccagcactcagctgcagaggcctctggtggtgttggc gaaaaacctgatgtgttatcccaggagttggggatggaagggcagaaatcacctgctgaa gaccagatgagaatgaaatgggaaagcctccatcaggaatttagcaccaagcagaaactg cttcagaatgttctacaacacgaaccagagcaagtgctttacagcaggccaaatcggctc ctgtctggcgtgccactgtacaaaggggacggacagccccaggataaatccgcggtgacg tctttgctggatggattgaaccaggccttcgaggaggtttcagcccagggtggagggaca aagaggcagaacactgacttggaacagaagttatacgatggggtctcagctacctctact tggctggatgacgtggaggatcgtttatttgctgccacagcacttttaccagcagaggcg gaaacttgcctctttaaccaagagactcttgccaaagatattaaggaaatgtctgaagaa atggataagaacaagaacttgttttcccaagcctttccagagaatggtgataaccgagat gttattgaagacactttgggttgtcttttgggcaggttatctttgctagactcagtagta aatcagcgatgtcatcagatgaaggaaagacttcagcaaatactaaatttccagaatgat ctgaaggtgctgtttgcatcactggctgaccacaagtacatcattctgcagaaactggca aatgtgtttgaacagcctgtggcagagcaaatagaggcaatacagcaggctgaagatggg ctaaaggaattggatgcgggaatcactgagttgaaaaggcgtggtgacaagctgcagatt gagcagccctgggtgcaagaactctccaaactccaggacatgtacgatgagctgatgatg accactggctcccggcggggcggtctgaaccagaatcttgcactgaagggtcagtatgaa agggccctgcaagatctggctgacctgctggagaccggacgcgagaagatggcaggagac cagaaaattatcgtgtcttccaaagaagacatccaacaactacttgacaaacataaggag tactttcagggcctggaatctcatatgatcttgactgaaacactcttcaggaaggttatc agctttgcggtcctacgggaaactcagttccacacagacctgatggagcaggcttcggct gtgctcaaaggggctcacaagaggggtgtggagttggagtacattctcgagacatggtcc catctggatgagaaccagcgggagcttagcaggcagctggaggtggtggagaccagcatc ccgactgtgggtttggtggaggagagcgaagacaggcttatcgaccggataacactctac cagcatttgaaatccagccttaatgaataccagcccaaattatatcaggtactagatgat gggaaacgacttctgatatctgttagctgctcagatctagaaagccagctaaatcaactt ggagaacactggttaaatgacaccaacaaagtgtctaaggaacttcacagattggaaaca atattgaaacactggaccagatatcaaagtgaatctgcagatctcatccactggttacag tctgcaaaagacaggctagaattttggactcaacaatctgtgacagttcctcaagaactg gaaatggtccgtgatcatctgaacgcttttctggagttttccaaagaggtggatgccaaa tctaccttgaaatcgtctgttctgagcactggaaatcagcttcttagactaaagaaagtg aacacagctgccctgcgttctgagctgtcacacattgatggccagtggactgacctgctg acaaatattccaaccgtacaggaaaagctccaccagctgcaaatggataagctgccttct cgccgtgccatttctgaagtcatggcttggatttctctcatggaaaatgttattcaaatg gatgaagagagtattaaaaactccatcggttacaaggcaattcatgaataccttcagaaa tataagggttttaagatcgacattaactgtaaacagctgactgtcgattttgtgaaccag tctgtgctacagatcagtagtcaggacgtggaaagtaaacgcagcgataagactgatttt gctgagcaacttggagcaatgaataaaagctggcaaatcctgcagggtctcgtcactgag aagattcagctgttggaaggcttattggaatcttggtcagaatatgaaaataacgtacaa ggtctgaaaacttggtttgaaacccaggaaaagagactaaagcaacaagagcgaattgga gatcaggcttcagttcagaacgcgctgaaagactgtcaggatctggaagatttgattaaa gcaaaagaaaaagaggtagagaaaattgagcagaatggacttgctttgattcagaacaag aaagaagaagcctctggcattgtcacgagcacacttcaggatctcaaccacacctgggca aatttagaccacatggttgggcagttaaagatcctgctgaagtctgtgcttgaccagtgg agccgccacaaagtggcctttgatgagataaacagttacctcatggaggccagatactct ctctcccgattccgtctgctgactggatctttagaagctgtgcaggttcaggtggacaat cttcagaatcttcaagatgatctagaaaaacaggaaaagagcttacagaaatttggctct atcaccaaccaactgttaaaagagagtcacccgcctgtgacagaaactcttaccgataca ctaaaagaagtcaatatgagatggaatcacttgctggaagagattgcagagcagctgcac gccagcaaggccctacttcagctttggcagagatacaaggactactccaaacagtgtgct gctacagttcaacagcaggagggtcgaaccaatgagctcttgaaggcagccactgacaag gacatcgcggacgacgaagttgccacatggattcaagattgcaatgacctcctcaaagga ctgaggacggttaaggattccctttttgttctccatgagctgggagagcaactcaagcaa caagtagatgcgtcggcagcatcagccattcaatctgatcaactctgtttgagtcaacac ttatgtgccctagaacaggctctttgcaaacagcaggctatgttacaggctggagttctt gactatgaaacctttaccaagagtttagaagctttggaagcctggatagtagaagctgaa gaaatactacaagggcaggaccctagccactcgtctgacctctcgaccatccaggaaagg atggaggaacttaagggacagatgctaaaattcagcagcatggtcccagatttagaccgg ctaaatgagcttggatacaggttgccgctaaatgataaagaaatcaaaaggatgcagaat ctgaaccggcactggtctctgatctccacccagactacagaaagattcagtaagttacag tcatttttgctacaacatcaaactttcttggaaaaatgtgaaacatggatggatttccta gttcaaacagaacagaagttagcagtagagatttcaggcaattatcagcatcttttggag cagcagagagcacatgagttgtttcaagcagagatgttcagtcgtcagcagattttacac tcgatcattgttgatggacagcatcttctagaacaaggtcaagttgatgacagggatgag ttcaacctcaaattgacccttctcagtaatcagtggcagggagtgatacgcagagcccag cagaggcggggcatcattgacagccagatccgccagtggcagcgctatcaggagatggcg gaaaagcttcgtaaatggttggttgaagtgtcctatctccccgtgagtggtctcggaagt gtcccaataccactgcagcaagcaaggaccctctttgatgaagtgcagttcaaagaaaaa gtgttcctgcgacagcaaggcagctacatcctcaccgtggaggctggcaagcagctcctg ctttctgccgacggtgcagctgaggctgccttgcaggctgaactcgctgaaatccaagag agatggagatcagccagtgtgcatctggaggagcagaagaaaaaactggccttcttgttg caggactgggaaaaatgtgagaacggaatagctgattctctggagaaactacgaaccttc aaaaagaggctctccccacctctgccagatcaccacgatgggctccacgcggagcagatg cgtggcaaggaattggaaaatgcagttgggagctggacagatgacctggcacggctgacg atgctgaaggatgcggtctgtgcctacatcagtgcagacgatatctccatccttaacgaa cgcatggagcttctgcaaaggcagtgggaagaactatgccaccagctctctttaaggcag cagcaagtaagtgagagactgaatgaatgggccgtcttcagtgaaaagaacaaggagctt tgcgaatggttgactcagatggaaagcaaaatttctcagaatggagacattctcattgaa gaaatgattgagaagctcaggaaggattatcaagaggaaattgctattgcccaagagaac aaaatacagctccagcaaatgggagaacgacttgcccgagccagccatgaaagcaaagca tctgagattgaatacaagctcgggaagatcaatgaccgatggcagcacctcctggacctc atggcagccagggtaaagaagctgaaggagaccctggtcgctgtacagcagctggataaa aacatgagcagcctgagaacgtggctggcccacatagagtcagagctggccaagccgatc gtctacgattcctgtgactcagaagaaatacagaaaaagcttaacaagcagcaggagctt cagagagacatagagaaacacagcacgggtgtggcctctgtcctcaacctgtgcgaggtt ctcctgcatgactgtgatgcctgtgccacagatgccgagtgcggttccatccagcaggct acgcgtaacctggaccggcgatggagaaatatctgtgctgtgtccatggaaagaaggcta aaaattgaagagacgtggagattgtggcagaagtttctggatgacttttctcgttttgaa gattggctgaaatgctcggaaagggtagctgccttccccagctcttctggggtgctctat acagttgccaaggacgaactaaagaaatttgagggtttccagcgacaggtccatgagacc ctgacccagctggaactgatcaacaagcagtaccgccgcctggccagagagaaccgcacc gactcggcgtgcagcctgaaacatatgatccacgaaggcaaccagagatgggacaacctg cagaagcgcgtcacctccatcttgcgcagactcaagcatttcattggccagcgggaggag tttgagactgcacgggacagcatcctggtgtggctgacagagatggatttgcagctcact aacattgagcatttttccgagtgtgatgttcaagctaaaataaagcaactcaaggccttc cagcaggaaatctcattgaaccacaataagattgagcagataattgcccaaggagaacag ctgatagaaaagagtgaacccctggatgccacgttcattgaagaagagttggatgaactc cgacgttactgtcaggaggtcttcgggcgcgtggaaagataccataagaaactgattcgc ctgcctctcccagatgacgagcacgacctctctgaccgggagctggagctggaggaggct gcagctctgtcggacctccactggcgcgacacctccgcggacagcgcgctctccccgcag cccgcctccaacccctccctctcactcgcccagcctctccagggcgagaggtccgggcga gacacccccgccagtgtggactccatccctctggagtgggaccatgactatgacctcagt cgtgacctggagtctgctgtgtccagaactctgccctctgaggatgaagagggtcaggaa gataaagatttctacctcaggggagctgttggtctgtcagatgtaacgatccccgaaagt cccgaggcctatgttaaactcacagaaagtgcaatcagaaatccctctggggatcctagc accttggagtcacagatccaacaactgggccaagccctggatgacagccactttcagatg cagcaaatggagaatattatccacagcaaaactcccgcaggaccagagctagactccagc tacagaggctatatgaaactgctgggtgaatgcagcggcagtatagactcagtgaaaaga ctggaacacaaactgacagaggaagaggagcattttccaggctttgttaacctgaacagc accgaaacccaaacagctggtgtgattgaccgctgggagctcctccaggcgcaggccctg agcaaggagctgaggatgaaacagaatccccagaggcggcagcggtttcactcggacctg ggccgcgttctgacctggctgcaggagacggaggacgacctggaacagctgcagcggcgg cagcgcagcactgatatccagcccatcgcgcttcagatcaaaaaactcaaggagctccag aaagctgtggaccaccacaaggccatcatcctctccatcaatctttgcagctccgagttc actcagcctggcagtgaggagagccaggacctgcagggccgcttgtcccagatgaatggc cgctgggaccgcgtgtgctccctgctggaggaatggcggggcctgctccaggacgcactg atgcagtgtcaggatttccatgaaatgagtcatggtttgcttctcatgcttgagaacatt gacagaaggaaaaatgaaattgtgccggttgattctaaccttgatgcagagatacttcag gaccatctcaaacagcttacgcaaataaggcatgagctcttggaatcccagctcaaagtg gcctcactgcaagacatgtctcgccaactattggtgaacgctgaaggcacagactgttta gaagccaaagaaaaagtgcatgtgattggaaatcggctcaaacttctcctgaaggaggtc agtcgtcatatcaaggagctggagaagttattagacatgtcaagcagtcagcaggatttg tcttcctggtcttctgctgatgaactggacacctcaggatctgtgagtcctacatcagga agaagtagcccaaacaggcagaaaacgccacgaggcaaatgtagtctctcacagcctgga ccctctgtcaacagtccacatagcaggtccataaaaggtggctccgattcctccctttct gagcctcggccagcccggtccggccgagccttcctgttcagagtcctccgagcggctctt cctcttcagcttctcctgctgttcctcattgggctcgcctgcctagtaccaatgtcacag gaagactacagttgcgccctctccaacaatttcgcccgatcattccaccccatgctcaga tacaccaatggccctcctccactctga

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