Papaver somniferum (opium poppy): 113298453 Help Entry 113298453         CDS       T05758                                  Name (RefSeq) auxin transport protein BIG-like   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism psom  Papaver somniferum (opium poppy) Brite KEGG Orthology (KO) [BR:psom00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:psom04121]     113298453 Enzymes [BR:psom01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      113298453 Ubiquitin system [BR:psom04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     113298453 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 UBR4 ZZ KAP_NTPase Motif Other DBs NCBI-GeneID:  113298453 NCBI-ProteinID:  XP_026402992 LinkDB All DBs Position 7:132724256..132743802 Genome browser AA seq 5093 aa AA seqDB search MAEISELLEVLHGEKTIKDLSQRLCNDSIKVGLEKFYFVLEKGVEEIEDGKLGLEYWNQL QIHSFISIATSIVSATRSLSLEKVEPIIVAILKQLLEFSTCFLEKSMFKCDDLSLQNNVL HLLEVALVGGTVEGTKPFNVNSLVDSLPIVPVKCTGVEFENHIKCTMQGISCARENPVDW VLMSLASEYQPPDSSVTSSTEFGFHQDWDNVISVSQNWAVVNGKCIQRLVKLCKELFQPP ESFDELTEGINFGARLSFSSRVLKLLGNLSRSIPCVAYDTDLLHEVACCADALPSLFRPR YEFVNCSSFAGENEYESLILSVLDEFLQFVELLFRDGNISLNIRTCIIASIFCILDADVW RYNKSDPDLKPPLAYFPRSVVNLLKRIGDVKKCASHSLSWLAKINKDVFVCRSGSEVNSP SCLVRSETVSLLKRYTSDELLKIVFPSSNQWVESLMHLVFFLHSEGVKLKPKVERSYSSC TKASGMSDLDNQVCHEDEALFGDLFSEAGRSVGSTDGIDQPPIPVTCIPSRSCMPIQAAT ELLTFLKCCIYSPEWSPSVYEDACQKLNVNHIDFLLSVLNCQACSIEEKSSETGSALPSK RKPGHINEVCFELLHSLLMQRAFSDSLEEHLVDQILMVENDTFMYNDHTLALVAHTLFGR VGSTRNQLRTKIYQGYANFIVEKAKSVSLTCPSLKEVLASLPSIFHIQILIMAFHLSPDE EKASLANLMFGSLRGADAPSAGFSSTQLSCWALVLSRLIVMLRYMIFYPSTCPSWLLQDL GSKLREAPFAGSCLPSYVNNHLLSWTSVSMQNMMGHLVKDESVVSSLLDQLIDVVTHPSS VCRDDQALRQLGLSWDEMCASFSWILELWKGKKAEAFEDLVLERYIFVLCWDIPTTSSTS SHLLPFGSSFQVAETFNVEYFFRFSHLLLSNSALVAKEAYFPEVIVSMLQHLETLVVSDN VKELGWDFMRDGSWLSLIVSLLQVGIFQYSVKKAIPGVDPLWSEGTIRDTEFMTVAECIV VAVLEGNSAALVFKLLSSLLKRYLVTYQEAFLSTFEEDNRFSTDKFSPLLLYKHTEFYNC SEENLPEKIGSSPYQLGSVYGLLSTLDSIVTRRGSGSVVPTFLCCLLHGFPMHPRSHSGH LLSCILTIKGIVCTLDGMMKLKDAGENICLETETVHQLLDSIMTVKSDRVFECTHGKCES ICYILNTSLQGPDYSYLFVMKHIEGFMKDINSKEANNSTSHEQLITRAIDFVEGVMKDPS KVDVFKFYMGTEEDISMEIKQLYCGQRGNLLVFIDALDRCHSESVNVKVLSFLADLLSGE TCPALKLDVQKKFLGMDLRCLSKWLEIRLLGCTTEVSAEVKGSSNALRESTMNFVKQVVS SPVEMQLRELHDHFVEALLMSLDTAFMLFDMHSAKSYFHFIVQLSNGESSMKHLLRSTMM LMEKLAGDECMLQGMAFLLGFLGSVLSSCGANNTILDDYSGKNLFSSNLAAGSIVSRSVS SRKESEALVLSASQQRGSTSIDCDGTSMDEDEDDGTSDGELGSIDKDEEEDSNSERALAS KVCTFTSSGSNFMEQHWYFCYTCDLTVSKGCCSVCAKVCHRGHRVVYSRLSRFFCDCGAG GVRGSSCQCLKPRKFTGSSSEQIQSASAFPSFPSFSEDGDQVPDSDTDLDDDVYVGIDSS FKLPISREVQDEISDLLEQLDMEGRVLKLCSSLLPLVISRRDCNLSKDKKVILGENKVLS YSADLLQLKKAYKSGSLDLKIKSDYSNARELKGHLSSGSLVKSLLSVSTRGRLAAGEGEK VSIFDVGQLIGQATVTPVTADKTNVKPLSKNIVRFEIVHLVFNTVVDNYLAVAGYEECQV LTVNPRGEVTDRLAVELALQGAYIRRIDWVPGSQVQLMVVTNMFVKIFDLSQDNISPVHY FTLPEDSIMDASLVVAPQGKMFLLVLSELGCLFRLELSIGGDVGAKPLKEIIKVQGKDIQ SKGLSLCYSSTYRLLFLSYQDGSSMIGRLDANATSIIEVSAVYEAKQDGKLRGAGLRHWK ELLSGAGLFTCFSSVKSNAVLTISMDPQEFFAQNMRHTAGSTLPIVGITAYRPLSKDKSH CLVLHEDGSLQIYSHLPVGVDATASSNLDQAKKLGSGILNNKTFAGLNPEFPLDFFEKTV CVTADVKLSSDAIRNSDSEGTKQSLASDDGFLESPSPSGLKITVSNSNPDMVMVGFRLHV GNTSSNHIPSEITIFQRVIKLEEGMRSWYDIPMSIAESLLADEEFTISVGPTFNASTLPR IDSLEVYGRPKDEFGWKEKMEAVLGMESHVLGSNSRAAGAGEKCRLIQSAPVQERVVADL LKLLSRFYSLCRPHGCCEIEEVKVEMSKLKCKQLVETIFESDREQLLQSSACHVLQSIFP KRETYYHVKDTMRLFGIVKSSPVLASRLGVGGATAGCVIEEFTTQMRAVSKIALHRRSNL AMFLETNGSGVVDGLMQVLWGILDIEQPDTQTINNIVIPSVELIYSYAECLALHGNDGGK HSVAPAVSLLKKLLFAPYEAVQTSSSLAISSRLLQVPFPKQTMLVTDDVVDNVVSVTLPS DIVRATGGNSQVMIEEDNITSSVQYCCDGCSTVPILRRRWHCTVCPDFDLCEACYEVLDA DRLPPPHSRDHPMSAIAIEMESIGGDSNEIHFSMNDTSESSVLPVTADVGVQNSPLPIHM LETNESGDFPDSVLDQRIVSISASKRAVNSLLLCELVEQLKGWMETTSGVRAIPVMQLFY RLSSAVGGPFMKSSKPENLDLEKFVKWFLDEINLNKSLVAKSRSSFGEVVILVFMFFTLM LRNWHQPGSDGSLLKSSGITETQDKTVTQVPLPASGNVVSVDSGEKNEFASQLLHACCSL RQQAFVNYLMDILQQSVSFFKSFSGNSEAAGSGCGSLLTVRRELPAGNYSPFFSDSYAKA HRADIFVDYHRLLLENTFRLVYSLVRPEKQEKSSEKDKVHKSSSSKDLKLDGYQDVLCSY ISNPNTSFVRRYARRLFLHLCGSKTHYYNVRDSWQMSNEVKKLYKLKNKSDGFRNPVPYE RSVKLVKCLSVLSEVAAARPRNWQKYCSRHGDVLPFLINGIFYFGEESVIQTLKLLNLAF YTGKDMGHCNQKVEVGDAGTGSVKSSSHSVDSKKKKKNEDGNDPSSEKPYLDMEQAVDTF SDRNDTTLRQFIDCFLLEWNSTSVRVEAKCVLYGIWHHGKQPFRETMLTVLLQKVKCLPM YGQNIIEYTELVTWILGKLPESNSSKQLETELVTRCLTPDVIRCIFETLHSQNELLANHP NSRIYNTLSGLVEFDGYFLESEPCVACSCPEVPCSRMKLESLKSETKFTDNRIIVKCTGS YTIQTVTMNVHDARKSKSVKVLNLYYNNRPVADLSELKNTWSLWKRAKSCHLAFNQTELK VEFPIPITACNFMIELDSFYENLQASSLESLQCPRCSRSVTDKHGICSNCHENAYQCRQC RNINYENLDSFLCNECGYSKYGRFEFNFMAKPSFVFDNMENDEDMKKGLSAIESESENAH RRYQQLLGFKKPLLKLVSSIGENEMDSQQKDSVQQMMVSLPGPSCKINRKIALLGVLYGE KCKAAFDSVSKSIQTLQGLRRVLMNYLHLKHSKNTPDSSRFAVPRSPNNCYGCATTFVTQ CLELLQVLSKHPSCKKQLVAAGILSELFENNIHQGPKTARIQARAVLCAFSEGDMNAVVE VNSLIQKKVMYCLEHHRSMDIALATCEELLLLSETCSVVDELWESRLRVAFQLLFSSIKL GAKHPAISEHVILPCLRIISQACTPPKPDGEKDQQTGKAGPTSVKEGNSVNPSGIMSSLG SVGKSTSDFSEKHWDTTQKTQDIQLLSYPEWEKGASYIDFVRRRYKVSQAVKSSGQRSRP QKFDYLALKYALRWRRLACKRTTKSDLSAFELGSWVSELALSACSQSIRSEMCTLISLLC AQSPSRRFRLLNLLMALLPATLSAGESAAEYFELLYKMIDSKDARLFLTARRCLPTICRL ITEEVVNVESQERSLHIDISQGFILHKLIELLSKFLEVQNIRSRFMGDDLLSDILEALLV IRGLVVQKTKLISDCNRLLKDLLDSLLLESSDNKRKFIRACISGLQTHGREKKGRTSLFI LEQLCNMICPSKPEPVYLLVLNKAHTQEEFIRGSMTKNPYSSAEIGPLMRDVKNKICHQL DMVGLIEDDFGMELLVAGNIISLDLSISQVYEQVWKKSHHHSQNTMGGSALVSANAFSTG KDCPPMTVTYRLQGLDGEATEPMIKELEEEREESQDPEVEFAIAGAVREYGGLEIILSMI QNLHDDELKLNQEELVSVLNLLMYCCKIRDNRRALLRLGALGLLLETARRAFSVDAMEPA EGILLIVESLTMETNESDISITQSVLTVTNEETGTAEQAKKMVLMFLDRLCHPSSLKKSN KQQRNTEMVARILPYLTYGEPAAMEALIQHFNSYLQDWVEFDQLQKQHEDNPKDESVAQQ AAKQRFALENFVRVSESLKTSSCGDSLKDIILEKGITAVAVRHLSDCFPFAGQAGFKSTA EWSLGLRLPSVPLILSMLRGLSRGHLATQRCIDDGGILPLLHALEGVPGENEIGARAENL LDTLADMERKGDGFLEEKIRDLRHATRDEMRRLALRKREELLQGLGMRQELTSDGGERIV VNHPIIEGLEDVEEEDGLACMVCREGYSLRPNDMLGIYSYSKRVNLGIGISGSTRGECVY TTVSHFNIIHFQCHQEAKRADAALKNPKKEWDGATLRNNETLCNCLFPLRGPAVPIAQYV RYVDQYWDNLNSLGRADGSRLRLLTYDIVLMLARFATGASFSTDCKGGGKESNSRFLPFM VQMARYLLDQGSSSSQQRRANAKSILAYLSDSKPSVPSGTRTQSATEETVQFMMVNSLLS ESYELWLSHRRAFLQRGIYHAYMQHAHGRSMLRISYDPTTIVKPEVGSSTESGGNNLFTV VLPMLVYVGLIEQLQHFFKLNKSGSATTSKKEGRPAEAEGELEAWEVVMKEKLLNVREMV GFSKEMLSWLDEMTSATDFQEAFDIMGVLPDVLSGGFSRCEDFVQASLHDGKS NT seq 15282 nt NT seq  +upstreamnt  +downstreamnt atggcagaaatctcagaacttttagaagttcttcatggagaaaaaacgataaaagatctt tcacaaagactttgtaatgattcgattaaagtaggcttagagaaattttatttcgttctt gaaaaaggagtcgaagagatcgaagatggaaaattagggcttgagtattggaatcagttg cagattcactcatttatatcgatcgctacatcaattgtttctgcaactcgatctctttca cttgagaaagtggaacctataattgtggcgatattgaaacagttgttggagttctcgaca tgttttctggagaaatcaatgtttaaatgcgacgatttgagtcttcagaataatgtgcta catttacttgaagtagcattagtcggtggcacggttgaagggacaaagccttttaacgta aatagtcttgtagactcactgcctattgttccagtcaagtgcactggtgttgaatttgag aatcacattaaatgcactatgcaaggtattagctgcgcaagagaaaaccccgttgactgg gttttgatgagtctggcttctgagtaccagccacctgatagcagtgtcacgagttcgaca gaatttggtttccatcaggattgggataatgttatctctgtatctcagaattgggccgtt gtcaatgggaagtgcatacagcgtctagttaagctgtgcaaagaactctttcagccacct gagtcatttgatgagctaacagagggtataaattttggtgcacgattgtcattcagttca cgggttctcaagttacttggaaatctttcaaggagcataccatgtgttgcttatgatact gatttgctacacgaagttgcttgctgtgctgatgcattaccgagcttatttaggcccaga tatgagtttgtgaactgcagttcttttgctggtgagaatgagtatgaaagcctcatacta tcagtcttggatgaatttcttcagtttgttgagcttcttttccgtgatggcaacatctcg ttgaatattcgaacttgtatcattgcttctatattttgcattttggatgctgatgtttgg aggtataataagtcagatccagacctaaagcccccattggcttattttcctcgcagcgtt gtcaacctactgaagcgcataggggatgttaagaagtgtgcctctcattctctcagttgg ctggcaaaaattaacaaggacgtattcgtttgtaggtctggttctgaggttaatagtcct tcatgtcttgttcgttcggagactgtttccttgctcaaaagatacacatctgatgaattg ttaaagatagtattcccttcttcaaatcaatgggtggagagtctaatgcatcttgttttt ttccttcactcagaaggagtgaagttaaagccaaaagttgagaggtcatattctagttgt acaaaagctagtggcatgtctgatttggacaatcaagtttgtcacgaggatgaagccctt tttggagatcttttctcggaagctggtcgttcagtaggttcaacagatggaattgaccaa cctcccattcctgttacttgtatcccaagccgtagctgtatgccgattcaagcagcaaca gagttgttaacctttctaaaatgttgcatctactcacctgaatggagtccttctgtttat gaagatgcatgtcaaaagcttaatgtgaaccatatcgatttcctgctttccgtgctaaac tgtcaagcctgttctatcgaagagaaaagctcagaaactggttcagctttaccttcaaaa agaaagcccgggcatattaatgaggtctgttttgagcttttgcatagccttctcatgcag cgtgctttttctgattcactggaagagcaccttgttgaccaaatccttatggtggaaaat gatacctttatgtacaacgatcacacccttgccttggttgcccataccctttttggcagg gtaggttcaactcgtaatcagttgaggaccaaaatctatcaagggtatgcgaatttcatt gttgaaaaggctaagtctgttagtttgacatgccccagcctgaaggaagttcttgctagt cttccttctatatttcacattcaaattcttattatggcatttcatttgtctcctgatgaa gaaaaggcatctcttgcaaacctcatgtttggttccctaagaggagctgatgctccctca gctggatttagcagcacccaactgtcttgctgggctttagtactttcaaggctcattgtg atgctacggtatatgatcttttatccatctacttgcccttcgtggttgctccaggatctt ggatcaaagttaagggaagctccgtttgctggatcatgccttcctagttatgtaaataat catctgttgtcatggacgtcagtatcaatgcagaacatgatggggcatttggttaaagac gaatcagttgttagtagcttgcttgatcaacttattgatgttgttactcacccttcttca gtctgcagagatgatcaggccttgcggcagttgggtttaagttgggatgagatgtgtgcc tctttttcatggattctggaattatggaaaggaaagaaggctgaagcatttgaagacctc gtgctagaaaggtacatttttgtactttgttgggatattcccaccacaagctcaacgtct tcacatctgcttccttttggaagtagcttccaggttgctgagaccttcaatgtggaatat ttcttccgctttagtcatctgctacttagcaactccgcccttgtggccaaggaagcttac tttcccgaagtcatagttagtatgcttcagcacttggaaacgctggttgtttcagataat gttaaggaactagggtgggatttcatgagggatggatcatggttgtcattaatagtttct ctactccaagttgggatctttcagtactccgtaaaaaaagcaatccctggtgtggatcct ctctggagcgaaggtacaattagggacactgagtttatgactgttgctgagtgcatcgtt gtcgctgtacttgaaggtaatagtgctgctttggttttcaagttgctgtcgtccttgtta aagaggtatttggtgacatatcaggaggctttcctcagtacattcgaggaggataacagg ttcagcacagataaattttctcctctacttctttacaagcacacagaattttataattgc tcggaagaaaaccttcccgagaaaattggatccagtccttatcagctgggctctgtttat ggcctcttgtcgacgttggacagcattgttaccagaagaggttcagggagtgtagttcct actttcctatgttgtttacttcatggtttcccgatgcatcctagaagtcatagtgggcat ctactttcttgtattcttaccataaagggtattgtctgcactctagatggcatgatgaag ctaaaagatgctggtgagaacatttgcttagagacggagactgtccaccagcttcttgat tccataatgactgtcaagtccgacagggtttttgagtgcactcatgggaagtgtgaatct atttgttacatactgaatacttctcttcagggtcccgactacagttatcttttcgtgatg aagcacattgaaggcttcatgaaagatatcaattcaaaagaagcaaataacagcacttcc catgaacagttaatcaccagggcgattgatttcgtggagggtgtcatgaaagacccttca aaagttgatgtttttaagttctatatggggactgaagaagacatatctatggaaatcaaa cagctttactgcgggcaacgtggaaatctactggttttcattgatgcattggatagatgt cattcagagtcagtaaatgtgaaggttctcagcttccttgctgatctgctgtctggagag acctgtcctgctcttaaattggatgttcagaagaagttccttggaatggatttgcgttgc ctatccaagtggctggaaattaggcttttaggttgcacaacagaagtttcagctgaggtt aaaggaagctcaaatgcactgagagagtcaaccatgaattttgttaaacaggttgtttcc tcgcctgtcgagatgcaactgcgagaactccatgatcattttgttgaagccttgctgatg tcgttggatactgcatttatgttatttgatatgcattctgcaaagtcatattttcatttt atagtccaactttcaaatggagaatcttcaatgaagcatcttttgagaagtactatgatg ctaatggagaagctggctggtgatgagtgtatgcttcaagggatggcatttctattgggc tttcttgggtctgtattgagtagttgtggagctaataatactatcctggacgattattct gggaagaatttgtttagcagcaatcttgcggcaggatctatagtttctagatcagtgagc tcaagaaaagaatctgaggcattggttctttctgcaagtcagcaaaggggttcgacatcg attgattgtgatggaacttctatggacgaagatgaagatgatggtacatctgatggggag ttgggtagcatagataaagatgaagaagaagacagtaacagcgaaagggcacttgcttct aaagtttgtacatttacatcaagtggtagcaactttatggagcaacactggtacttctgc tatacttgcgacttgacagtttctaaaggctgttgttctgtctgtgccaaggtttgccat cgtggtcatcgagtcgtttattctcgtttgagtcgttttttttgtgattgcggtgctgga ggtgtcagaggaagcagttgccagtgcctgaagcctcggaagttcactggaagcagcagc gaacagattcaatctgccagtgcttttccatcttttccctccttttctgaagatggagat caggtacccgatagtgatacagatctggatgatgatgtttatgttggtatagatagttcc ttcaagttgcccatatccagggaggttcaagatgaaatctctgatctattggaacaactt gatatggagggccgggtgcttaagttgtgtagctcgttgttgcccttggtaataagcaga agggactgtaacctttcgaaagacaaaaaagtaatactgggtgaaaataaagtcttatct tacagtgctgatcttctgcagctgaagaaggcatacaaaagtgggtcacttgacctgaag ataaaatctgattattcaaatgccagggagctcaagggtcatctgtctagtggttccctc gtaaaatccttgctgagtgtgagcactcggggaagacttgcagctggagagggagaaaaa gtttcaatatttgatgttggccagcttattgggcaggctactgttactcctgtgacagca gacaaaaccaatgtcaagcccctttctaagaatattgtacgttttgaaattgtacatcta gtgttcaatacagttgtagataactatctggctgtagcaggctatgaggaatgccaagtt ctcacagtgaaccctcgaggtgaagtgactgatcgtcttgcagttgaacttgctctgcaa ggtgcctatatccggcgaatagattgggtcccaggttcacaagtgcagttgatggtggtc acaaacatgtttgtcaagatatttgacttatcacaagataacattagtcctgttcactat tttacgctgcctgaggattcaatcatggatgcatcacttgttgtggctcctcaagggaag atgtttctgcttgttttgtcggagcttggatgcttatttaggctggagttgtctataggg ggtgatgttggggccaagccactgaaggaaattatcaaggttcagggtaaggacattcag tcgaaaggtttgtcgttgtgctattcatcaacatatagattactgttcttatcgtatcaa gatggaagtagcatgattgggagattagatgccaatgcaacatcaataattgaggtgtct gctgtatacgaggccaaacaagatggtaagctgagaggtgctggattgcgtcattggaaa gaattactgtctggtgctgggttatttacttgtttctcaagtgttaaatcaaatgctgtg cttactatttcaatggaccctcaggagttttttgcacagaacatgcgccatactgctggc tctaccttgcctattgttggaataactgcctacaggccgttatctaaagataaatcccat tgccttgttttgcatgaagatggcagtcttcagatttactcacatcttcctgtgggggtt gatgccactgcaagttcgaacttggatcaggcaaagaaattgggatctggtattcttaac aataaaacatttgctggtttaaatccagaatttccacttgatttttttgagaaaacagtt tgcgtcacagcagatgtgaaactaagtagtgatgctatcagaaacagtgattctgaagga actaagcaaagcttggcatctgatgatggtttcctagaaagtcccagtccttcaggatta aagattactgtttctaattcaaacccggatatggtcatggttggtttccgcctacacgtt ggtaatacgtcatcaaaccatattccatctgaaataactattttccagagagtaattaaa ctggaagaagggatgcgttcttggtatgatattccaatgtcgattgctgaatcactcctc gccgatgaagaatttactatctctgtgggcccaacattcaatgcatccacactgcctaga atagattcattagaagtatatggtcgaccaaaagatgaattcggttggaaagaaaaaatg gaggctgtgctgggtatggaatcccatgtgcttggttccaattctcgggcagctggagct ggggaaaagtgccgtttgattcaatctgctccagttcaagaacgggttgtcgcagatcta cttaaacttttatctaggttttattcattgtgcaggccacatgggtgttgtgagattgag gaagttaaagtggagatgagtaaactcaaatgcaagcagttggtagaaacaatatttgag agtgaccgagaacagttgttgcagtcttctgcttgccatgttcttcaatctatcttcccc aaaagggaaacatactatcatgtaaaggacacaatgcgcctttttgggattgtcaagtct tcgcctgtgcttgcttcaaggctgggtgttggtggtgcaacagcgggctgtgtaattgaa gagtttacaacgcagatgcgtgcagtgtcaaagattgcattacaccggagatcgaacttg gccatgtttttggaaactaatggttctggagtagttgacggactgatgcaagttctctgg ggaattttggatatagagcaaccagacacacagacaataaacaatattgtaataccctca gtggaactcatttacagttatgctgaatgtctggctttgcatggaaatgatggtggaaag cactctgtcgcgcctgctgtttcattactaaagaaacttctttttgccccttatgaggct gttcagacttctagcagcttggctatatcttcaagattgctccaggttccatttccaaag cagaccatgttggttacagatgatgtggtggataatgttgtgtctgtaactctcccttct gatattgtgcgtgcaacgggtggaaattcccaagtcatgattgaagaagacaatataaca tcatcggtccagtactgctgcgatggttgctccactgttcccatacttcgacgccgttgg cactgtactgtgtgccctgattttgatctatgtgaggcatgctatgaagtacttgatgct gatcgtcttcctcctccacattccagagatcatcctatgtcagcaatagcaatcgaaatg gagtccataggcggagatagcaacgaaattcatttctcgatgaatgatacaagtgagtcg agtgtgttgccagttactgctgatgttggtgtccaaaattctccactgccaattcatatg ctggagaccaatgaatctggtgatttccctgattctgttcttgatcaaagaatagtatcc atctcagcatcaaaacgagctgttaattctcttcttctctgtgagctagtagaacaactg aagggttggatggagacaacttctggtgtcagggctattcctgtaatgcaattattctac agattatcatctgctgtgggcggtccttttatgaagagctcaaaacctgaaaatttggat ttggagaaatttgtcaagtggtttttggatgagatcaatctgaataaatctcttgtagct aaaagccgttcttcttttggtgaagttgtaatccttgtcttcatgttcttcaccttgatg cttagaaactggcatcagcctggcagtgacggttctctactaaaatcaagtggaattact gagacacaagacaaaactgtgacccaagttccactgccggcttcaggcaatgttgtttct gtagacagtggggagaaaaatgagtttgcgtctcagttgcttcatgcttgctgctctctc agacaacaagcttttgttaattatctgatggatattttgcaacaatcggtaagttttttt aagtctttcagtggaaattctgaagctgctggttctggatgtgggtctcttctgacagtt cggagagagttacctgctggaaactactcgcctttcttttctgattcgtatgccaaagcc catcgtgcagatatttttgtggactaccacaggttactcttagagaacacatttcgactg gtttatagtttggttaggccagaaaaacaagaaaagtccagtgaaaaggataaggttcac aaaagttcttcctccaaggatttgaagctagatggttatcaggatgttctttgcagctat atcagcaaccctaatacgtcgtttgtcaggcgatatgcaagaaggctatttctgcatcta tgtgggagtaaaacacattattacaacgtgagagactcttggcagatgtcaaatgaagtt aagaagctttataaacttaaaaataaatctgatggttttcggaatcctgtgccatatgag agaagtgttaaacttgtcaagtgcctgtctgttttgtccgaggtagcagctgcgaggcct cgtaattggcaaaaatattgttctagacatggggatgttctaccgtttttgataaatgga atcttttattttggggaagaatctgttattcaaactcttaaactcttgaatttggctttc tacacagggaaggatatgggccattgtaatcagaaagttgaggtaggagatgcaggtaca ggttctgtaaaatccagttcacattctgtggattcaaagaaaaagaagaaaaatgaggat ggaaatgaccctagttcggagaaaccttatctagacatggaacaggctgttgatactttc agtgacagaaatgacactactttgaggcagtttattgattgctttttactcgagtggaac tccacatctgtacgtgttgaagctaagtgtgttctatatgggatatggcatcatggaaaa cagccattcagggagaccatgttgacagttcttttacagaaagtgaagtgcttgccaatg tatggtcagaacattatcgagtacacagagctagttacttggatactggggaaactgcct gagagtaatagttcaaagcaactggagacagagcttgtcacacggtgtttgactcctgat gtgataaggtgcatctttgagactcttcactcacaaaacgagcttttggccaatcatcca aattcacgcatttataacactttgagtggtttggtcgaatttgatgggtactttctcgaa agcgagccttgtgttgcctgtagttgtccagaggtgccttgcagcaggatgaagctagag agccttaaatctgaaacaaagtttaccgacaaccgaataattgtgaaatgtactgggagc tataccattcagactgtgacaatgaatgttcacgatgctcgcaaatcaaaatctgtgaag gtgttgaatctatactacaacaataggccagtggctgatttgtcggagttgaagaatact tggtccttatggaaacgcgcaaaaagttgtcatcttgctttcaaccaaacggagttaaag gtagaatttcctattccaatcactgcttgcaatttcatgattgagctcgactccttctat gagaatctccaagcttcctcccttgagtcgttgcagtgccctcggtgcagcaggtccgtt actgataaacatggcatttgcagcaattgccatgaaaatgcatatcaatgcagacaatgt cgcaacataaattatgagaatttggattctttcctttgcaatgagtgtgggtatagcaaa tatggacgttttgaatttaatttcatggcaaagcctagtttcgtgtttgataacatggaa aatgacgaggatatgaaaaaaggattgtcggctattgaatctgagtcggaaaatgcccat aggagatatcagcaactgctgggtttcaaaaaacccttgcttaaacttgtgtcgagcatc ggtgagaatgaaatggactcgcaacagaaagattctgtccagcaaatgatggtctctttg ccagggccgtcttgtaaaataaatcgcaaaattgctcttcttggtgtactgtatggtgag aagtgcaaagcagcgtttgactctgttagtaaaagtatccaaactcttcaaggtcttcgc cgtgttttaatgaactatctgcatctgaaacattctaaaaacacaccggattcgtcaagg tttgctgttcccaggtctccgaataactgttatggttgtgccacaacatttgtcacccag tgcttggagttgctgcaagtcttatctaaacacccaagttgtaagaagcagcttgttgca gctggcatcttgtcggagttgtttgaaaataacatccaccagggtccaaaaacagcacgc atccaggctagggcggtgctctgtgcattctcagaaggtgatatgaatgcagtggttgag gtgaacagtttgatacaaaaaaaggtcatgtattgtctcgagcaccatcgctccatggac attgcattggctacatgcgaggagttactattgctatctgagacctgttctgtggtagat gaattgtgggaatcaaggttacgtgttgctttccagttattattttcttccatcaagctg ggcgctaaacatcctgctatatctgagcatgttattcttccgtgtctgagaattatttct caggcatgcactcctccaaaacctgatggagagaaggaccaacaaaccggaaaggctggt cccacttctgtaaaagaaggaaacagtgtaaacccatctggtattatgagcagtcttgga agtgtgggcaagtccacatcagatttttccgaaaaacattgggatacaactcaaaaaacc caagatatccaactgcttagctaccccgagtgggaaaagggggcttcatatattgatttt gtcagaaggcgatataaagtgtctcaggcagttaaaagttctggccagaggtctcgacct caaaagttcgactatctggctctgaagtatgcacttagatggagaaggctcgcttgtaaa agaacaacgaagagcgacttatcagcatttgagcttggttcatgggtctctgagttggca ttgagtgcttgttcacaatctataaggtcagagatgtgcaccttgatcagtttactttgc gcacagagtccatcgaggcgattccgacttttaaacttgctcatggcattgcttccggct actctgtctgctggagaaagtgcagcagaatattttgagttgctctacaaaatgatagat tccaaagatgcccgcttatttctcactgctaggaggtgtttacctacaatttgtcggtta ataactgaagaggtggtcaacgttgaatctcaggagagaagtcttcatattgatatatcg cagggattcatccttcataagcttattgagctcctcagcaaatttcttgaggtccagaat atccgttctaggtttatgggagatgacttgttgtccgatatccttgaggctcttcttgtc attcggggcctggtagtgcagaagacgaagctgattagtgattgcaatcgtcttttaaaa gatctcctggacagtctgcttcttgagagtagtgataacaaaagaaaattcatacgggcc tgcatatctggtttacagacacatggacgggagaagaaaggtcgaacttctctgttcatt ttggaacaactatgcaatatgatatgtccatcaaagccagagcctgtttatcttttggtt ttgaacaaggcgcatacccaagaagagttcatcaggggatcaatgaccaaaaatccgtat tcaagtgctgagattggtcccttgatgcgagatgttaaaaacaaaatttgtcaccagttg gatatggtagggcttattgaggatgacttcggcatggagttgctagtagctggaaatata atctctcttgatttgagcatctctcaagtttatgagcaggtttggaagaagtcgcatcat cattctcaaaataccatgggaggttctgctttagtatctgctaatgcattttcaactggc aaagactgtccaccaatgacagtcacctacaggcttcagggacttgatggtgaagctact gaacccatgatcaaagagttagaagaagaaagggaggagtcacaggatcctgaggttgaa tttgcaatagcaggtgctgttcgggagtatggggggcttgaaataattttgagcatgatc cagaatttgcatgatgacgagttgaaactgaaccaagaagagttggtttctgtgcttaat cttctcatgtattgttgcaaaattagagacaacagacgggccttgttacggctaggagct ttagggttgcttcttgaaactgcaaggcgtgctttttctgtggatgcaatggagccagct gaaggcattcttttaattgtggagagcctgacaatggagacaaatgagagtgatattagc atcactcagagtgtgctcacagttactaatgaagagactggtactgctgaacaggcaaag aaaatggtcctcatgttcttagatagattatgccatccttcaagccttaaaaagtcgaac aagcagcaaagaaatactgaaatggtggcaaggatcttgccttacttgacttacggagag cccgcggcaatggaagcactaatccagcattttaattcttatctccaggactgggttgaa tttgatcagctgcaaaaacagcatgaggataaccctaaggatgagagtgtggctcaacaa gctgccaaacagaggtttgctttggaaaactttgttagggtttccgagtcactgaagaca agttcctgtggggacagcctgaaggacatcatattagaaaagggtattactgcggttgct gtcagacatttgagtgattgttttccatttgctgggcaagctggatttaaatcaactgct gaatggtcacttgggctaaggttaccatctgtcccgctaatcttatctatgctccgtgga ctttctagggggcatttggcaacacaaagatgtattgatgatggggggatcttaccattg ctccatgctctggagggggttcctggggaaaatgagataggtgcaagggctgagaactta ttagacacacttgctgatatggagaggaaaggtgatgggttcctggaagagaagatccgt gatttgcggcatgcgacgagagatgagatgcgtcgtctagcactgaggaagagagaagag ttgctccagggtctcgggatgcgtcaagaattaacttcagatggtggtgaacgaattgtg gtgaaccacccaattattgagggcttggaagatgtggaagaggaagatgggctggcgtgc atggtgtgccgagagggttacagtttgaggccgaatgatatgttgggaatatattcttac agcaagcgagtaaaccttggaatcgggatatcggggagtacaagaggtgagtgtgtttac acgacagttagccatttcaacatcatacatttccagtgtcatcaagaagccaaacgagct gatgctgctctgaaaaatccaaagaaagagtgggatggagctacccttagaaacaatgag actctttgcaactgcctatttccattgagaggccctgctgttcccattgcacaatatgtc cgttatgttgatcaatactgggacaacctcaattcccttgggcgtgctgatggaagccgt ctccgtttgttgacttacgatatcgttctgatgctggcacgatttgcaactggtgcttca ttcagtactgactgtaaaggtggaggtaaagagagcaattcacggttccttcctttcatg gttcagatggcacgttaccttcttgatcaaggaagctcatccagtcagcaacgtcgagcc aatgcgaagtctatattggcctacttatcagattccaagccttccgttccatctgggacc cgtactcaatcagcaactgaagagactgttcagttcatgatggttaactcactcctctca gaatcttatgaactgtggctgagccaccgccgtgcattcttacaacgtgggatataccat gcatacatgcagcacgcacatggtcgatcaatgctccgtatttcctatgatccaaccact atcgttaaacccgaagttgggtctagcactgaaagtggaggcaacaacctatttactgtt gtcttgccaatgctcgtttatgttggtttaattgaacagttgcagcattttttcaagctg aacaaatctggaagtgcaacaacctctaagaaagaaggaagacccgcagaagcggaggga gaattagaagcttgggaagtggtgatgaaagagaaactactgaatgtaagagaaatggtg gggttctctaaagagatgctttcatggctggacgagatgacttctgcaacagacttccaa gaagcgtttgatataatgggagttttacctgatgtactctctggtggattttcacggtgc gaagattttgttcaagcttcattgcacgacgggaaaagctaa

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