KEGG   Pelodiscus sinensis (Chinese soft-shelled turtle): 102443595
Entry
102443595         CDS       T02980                                 
Symbol
MAP2K1
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 1 isoform X1
  KO
K04368  mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
Organism
pss  Pelodiscus sinensis (Chinese soft-shelled turtle)
Pathway
pss04010  MAPK signaling pathway
pss04012  ErbB signaling pathway
pss04068  FoxO signaling pathway
pss04114  Oocyte meiosis
pss04140  Autophagy - animal
pss04148  Efferocytosis
pss04150  mTOR signaling pathway
pss04210  Apoptosis
pss04218  Cellular senescence
pss04270  Vascular smooth muscle contraction
pss04370  VEGF signaling pathway
pss04371  Apelin signaling pathway
pss04510  Focal adhesion
pss04540  Gap junction
pss04620  Toll-like receptor signaling pathway
pss04810  Regulation of actin cytoskeleton
pss04910  Insulin signaling pathway
pss04912  GnRH signaling pathway
pss04914  Progesterone-mediated oocyte maturation
pss04916  Melanogenesis
pss05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:pss00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102443595 (MAP2K1)
   04012 ErbB signaling pathway
    102443595 (MAP2K1)
   04370 VEGF signaling pathway
    102443595 (MAP2K1)
   04371 Apelin signaling pathway
    102443595 (MAP2K1)
   04068 FoxO signaling pathway
    102443595 (MAP2K1)
   04150 mTOR signaling pathway
    102443595 (MAP2K1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102443595 (MAP2K1)
   04148 Efferocytosis
    102443595 (MAP2K1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    102443595 (MAP2K1)
   04210 Apoptosis
    102443595 (MAP2K1)
   04218 Cellular senescence
    102443595 (MAP2K1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102443595 (MAP2K1)
   04540 Gap junction
    102443595 (MAP2K1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102443595 (MAP2K1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102443595 (MAP2K1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102443595 (MAP2K1)
   04912 GnRH signaling pathway
    102443595 (MAP2K1)
   04914 Progesterone-mediated oocyte maturation
    102443595 (MAP2K1)
   04916 Melanogenesis
    102443595 (MAP2K1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    102443595 (MAP2K1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102443595 (MAP2K1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pss01001]
    102443595 (MAP2K1)
Enzymes [BR:pss01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     102443595 (MAP2K1)
Protein kinases [BR:pss01001]
 Serine/threonine kinases: STE group
  STE7 family
   102443595 (MAP2K1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7
Other DBs
NCBI-GeneID: 102443595
NCBI-ProteinID: XP_006129228
Ensembl: ENSPSIG00000011457
LinkDB
Position
Unknown
AA seq 404 aa
MPKKKPMPIQLNPAPDSSTINGTSTAEFFFGGSSQLTNLEALQKKLEELELDEQQRKRLE
AFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLIMARKLIHLEIKPAIRNQI
IRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSI
AVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMS
PERLQGTHYSVQSDIWSMGLSLVEMAIGRYPIPPPDSKELELMFGCPVEGDSSVSETSPR
QRTPGRPMSSYGPDSRPPMAIFELLDYIVNEPPPKLPNGVFSPEFQDFVNKCLIKNPAER
ADLKQLMIHVFIKRSEAEEVDFAGWLCSTIGLNQPSTPTHAAGI
NT seq 1215 nt   +upstreamnt  +downstreamnt
atgcctaaaaagaagccgatgccaattcagctgaacccggctccagatagctccaccatc
aatgggaccagcactgcagagtttttctttggagggagcagtcagctgacaaatttagag
gcactgcagaagaagctggaggagttagaattggatgagcagcaacgtaaacgtcttgaa
gctttccttacgcagaagcaaaaagttggggagctgaaggatgacgacttcgagaaaatc
agtgagctgggagcagggaacggcggcgtggtcttcaaagtctctcacaaaccttctggc
ctcattatggcaagaaagttaattcacttagagatcaagccggctattcgaaaccagatc
attcgtgagctacaagtgctacatgaatgtaactcgccatatatagtaggcttttacggg
gctttttacagtgatggagagatcagcatttgcatggaacacatggatggtgggtccttg
gatcaagtcctgaaaaaagctggaagaattccagagcagattttgggcaaagttagcatt
gctgtaatcaaaggtctcacatatttgagagaaaagcataagataatgcacagagatgtt
aaaccatcgaacattttggtaaactctagaggtgaaatcaagctttgtgattttggtgtc
agcggacagctgatagattcaatggcaaactcatttgttgggacgaggtcctacatgtct
ccggagagacttcaaggtacccattattcagtgcagtcagacatctggagcatgggattg
tcactggtagaaatggccattggcagataccccattcccccgcctgattccaaggagctg
gagctgatgtttggctgccctgtggagggagactcttccgtttctgagacttcacctaga
caaagaacacctggccgtccaatgagctcttacggaccagacagcaggccaccaatggca
atctttgaacttctggactacatcgtcaatgagccacctccaaaattgcccaatggtgtt
ttctctcctgaatttcaagattttgtgaacaaatgcttaataaaaaatccagcagagaga
gcagatttgaagcaactcatgattcatgttttcattaaaagatctgaagccgaggaagtg
gattttgcaggatggctttgttcgactataggcctcaaccagcctagtacgcctacacac
gcggctggaatctga

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