Pseudoliparis swirei (Mariana hadal snailfish): 130207366
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Entry
130207366 CDS
T09868
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pswi
Pseudoliparis swirei (Mariana hadal snailfish)
Pathway
pswi00270
Cysteine and methionine metabolism
pswi00480
Glutathione metabolism
pswi01100
Metabolic pathways
pswi01240
Biosynthesis of cofactors
pswi04216
Ferroptosis
Module
pswi_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pswi00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
130207366 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
130207366 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
130207366 (gclc)
Enzymes [BR:
pswi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
130207366 (gclc)
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
130207366
NCBI-ProteinID:
XP_056291917
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Position
17:11999004..12007541
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AA seq
630 aa
AA seq
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MGLLSQGSPLNWEETKKYADHIRKHGVIQFLNIYNKLKERQKDVLKWGDEVEYMLLELDD
KDETVRLVLTGNEVLETLQDQGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMGKRRREASAVLNPNETLCTITAFPRLGCPGFTKPEHRPTPVEEGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGGKVVINVPIFKDKCTPSPFVEEFPEDDGEAASAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAAAPFYRGFVSDNDCRWGV
ISDSVDDRTMEERGLKPLKNNKYRIFKSRYDSIDSYLSSCSEKYNDIDLTIDEEINKQLL
DAGIDKLLAQHIAHLFIRDPLSVFEEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNSV
HEGMFYFRKDIFKGCNPGLDGAASAENGVETDDAKEEYTLMSIDTIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVAQHPQYKQDSVLTEKI
NYDLFKKCDRIAKGEEQCPELIGNPVNRFK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtttactgtcgcaggggtctccgctgaactgggaggaaaccaagaagtatgcggac
cacatcagaaagcacggcgtcatccagttcctcaacatctacaacaagttgaaggagcgt
cagaaagatgtgttgaagtggggcgacgaggtcgagtacatgttgctggaattggatgac
aaggatgaaaccgttcgactcgtcctcaccggtaatgaggttctggaaaccctccaagac
cagggtgaaaagataaaccccaatcaccccacgctttggaggccagagtacggcagctac
atgatcgaaggaacgccggggcagccgtacggcgggacgatgtcagagttcaacaccgtg
gagggcaacatgggcaagaggcggcgagaggcctcggctgtcctgaaccccaatgaaacc
ctctgcaccatcaccgcatttccaaggttaggctgtccaggtttcaccaaaccagaacac
cggccgacccctgttgaagagggagtgtcgaagtcactgttttttccagatgaagcgatc
aacagacatccaagattcagcacccttaccagaaacatacgtcacagaagaggagggaaa
gttgtgattaatgtgccaatcttcaaagacaagtgcactccatctccatttgtggaggag
tttcctgaggatgacggtgaggcggcgagcgcggcgctgccagatcacatctacatggac
gccatgggcttcgggatgggcaactgctgtctgcaggtgacgttccaagcctgtagcatt
gatgaggcgagatatctttatgaccaactagcaacattctgccccatagtgatggcgctg
agtgcagccgctcccttctacagaggctttgtgtcagataatgattgtcgttggggagtt
atttctgactctgtggatgaccggacgatggaagaacgcgggctcaagcctttgaaaaac
aataaatacaggatcttcaagtccagatatgattccattgacagctacctgtctagctgc
agtgagaagtacaacgacatcgacttgacgatagacgaggagatcaacaagcagctgctc
gacgcaggaattgacaagctgctggcccaacacatagcacacctcttcatccgagatccg
ctctccgtctttgaggagaaaatccacttggatgatgaaaacgagtcggatcactttgag
aacctccagtcgaccaactggcagacgatgaggttcaaacctccaccgccaaactctgac
attggctggagagttgagttccgccccatggaggtgcagctcactgactttgaaaacgct
gcatacgtggtgtttgtcgtcctgctcaccagagtgatcttgtcttataaactggacttt
ctgatccctttgtcaaaggttgatgaaaatatgaaggtcgcacagaagagaaactctgtc
cacgagggcatgttttacttccgcaaggacatcttcaaaggctgcaacccgggccttgat
ggcgcagcctcggcggagaacggcgtggagactgatgacgctaaggaggagtacacgctg
atgagtatcgacacaatcatcaacggaaaggagggagtgtttcaagggcttatcccgatc
cttaactgctacctggagaacatggaagtggatgtggataccaggtgcaccattttgaat
tatctgaagctcatcaagaaacgtgcctcaggtgaactgatgactatggccaagtggatg
agggaatttgttgcccagcacccgcagtacaagcaggacagcgtcctgactgagaagata
aactacgacctgttcaagaagtgcgacaggatagccaaaggtgaagagcaatgccctgag
ctcattggaaacccagtcaaccggttcaaatga
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